6DU5

Crystal structure of hMettl16 catalytic domain in complex with MAT2A 3'UTR hairpin 6

Summary for 6DU5

Entry DOI	10.2210/pdb6du5/pdb
Descriptor	U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase, hp6-RNA (25-MER) (2 entities in total)
Functional Keywords	m6a methylation, methyltransferase, protein-rna structure, m6a, n6-methyladenosine, transferase-rna complex, transferase/rna
Biological source	Homo sapiens (Human) More
Total number of polymer chains	2
Total formula weight	44912.81
Authors	Doxtader, K.,Wang, P.,Nam, Y. (deposition date: 2018-06-19, release date: 2018-09-26, Last modification date: 2018-10-03)
Primary citation	Doxtader, K.A.,Wang, P.,Scarborough, A.M.,Seo, D.,Conrad, N.K.,Nam, Y. Structural Basis for Regulation of METTL16, an S-Adenosylmethionine Homeostasis Factor. Mol. Cell, 71:1001-1011.e4, 2018 Cited by PubMed: 30197297 DOI: 10.1016/j.molcel.2018.07.025 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.006 Å)

Structure validation