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PDB: 51 results

2BUD
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BU of 2bud by Molmil
The solution structure of the chromo barrel domain from the males- absent on the first (MOF) protein
Descriptor: MALES-ABSENT ON THE FIRST PROTEIN
Authors:Nielsen, P.R, Nietlispach, D, Buscaino, A, Warner, R.J, Akhtar, A, Murzin, A.G, Murzina, N.V, Laue, E.D.
Deposit date:2005-06-09
Release date:2005-06-24
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structure of the Chromo Barrel Domain from the Mof Acetyltransferase
J.Biol.Chem., 280, 2005
6VPS
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Cryo-EM structure of the amyloid core of Drosophila Orb2 isolated from head
Descriptor: Translational regulator orb2
Authors:Hervas, R, Rau, M.J, Park, Y, Zhang, W, Murzin, A.G, Fitzpatrick, J.A.J, Scheres, S.H.W, Si, K.
Deposit date:2020-02-04
Release date:2020-03-18
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Cryo-EM structure of a neuronal functional amyloid implicated in memory persistence in Drosophila
Science, 367, 2020
8A9L
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Cryo-EM structure of alpha-synuclein filaments from Parkinson's disease and dementia with Lewy bodies
Descriptor: Alpha-synuclein, Unknown fragment
Authors:Yang, Y, Shi, Y, Schweighauser, M, Zhang, X.J, Kotecha, A, Murzin, A.G, Garringer, H.J, Cullinane, P, Saito, Y, Foroud, T, Warner, T.T, Hasegawa, K, Vidal, R, Murayama, S, Revesz, T, Ghetti, B, Hasegawa, M, Lashley, T, Scheres, H.W.S, Goedert, M.
Deposit date:2022-06-28
Release date:2022-08-31
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (2.2 Å)
Cite:Structures of alpha-synuclein filaments from human brains with Lewy pathology.
Nature, 610, 2022
6GX5
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Narrow Pick Filament from Pick's disease brain
Descriptor: Microtubule-associated protein tau
Authors:Falcon, B, Zhang, W, Murzin, A.G, Murshudov, G, Garringer, H.J, Vidal, R, Crowther, R.A, Ghetti, B, Scheres, S.H.W, Goedert, M.
Deposit date:2018-06-26
Release date:2018-09-12
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structures of filaments from Pick's disease reveal a novel tau protein fold.
Nature, 561, 2018
1Z0R
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BU of 1z0r by Molmil
Solution Structure of the N-terminal DNA Recognition Domain of the Bacillus subtilis Transcription-State Regulator AbrB
Descriptor: Transition state regulatory protein abrB
Authors:Bobay, B.G, Andreeva, A, Mueller, G.A, Cavanagh, J, Murzin, A.G.
Deposit date:2005-03-02
Release date:2005-03-15
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Revised structure of the AbrB N-terminal domain unifies a diverse superfamily of putative DNA-binding proteins.
Febs Lett., 579, 2005
1GUW
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BU of 1guw by Molmil
STRUCTURE OF THE CHROMODOMAIN FROM MOUSE HP1beta IN COMPLEX WITH THE LYSINE 9-METHYL HISTONE H3 N-TERMINAL PEPTIDE, NMR, 25 STRUCTURES
Descriptor: CHROMOBOX PROTEIN HOMOLOG 1, HISTONE H3.1
Authors:Nielsen, P.R, Nietlispach, D, Mott, H.R, Callaghan, J.M, Bannister, A, Kouzarides, T, Murzin, A.G, Murzina, N.V, Laue, E.D.
Deposit date:2002-02-01
Release date:2002-03-12
Last modified:2018-01-17
Method:SOLUTION NMR
Cite:Structure of the Hp1 Chromodomain Bound to Histone H3 Methylated at Lysine 9
Nature, 416, 2002
6NWP
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Chronic traumatic encephalopathy Type I Tau filament
Descriptor: Microtubule-associated protein tau
Authors:Falcon, B, Zivanov, J, Zhang, W, Murzin, A.G, Garringer, H.J, Vidal, R, Crowther, R.A, Newell, K.L, Ghetti, B, Goedert, M, Scheres, H.W.
Deposit date:2019-02-07
Release date:2019-03-27
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (2.3 Å)
Cite:Novel tau filament fold in chronic traumatic encephalopathy encloses hydrophobic molecules.
Nature, 568, 2019
6NWQ
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Chronic traumatic encephalopathy Type II Tau filament
Descriptor: Microtubule-associated protein tau
Authors:Falcon, B, Zivanov, J, Zhang, W, Murzin, A.G, Garringer, H.J, Vidal, R, Crowther, R.A, Newell, K.L, Ghetti, B, Goedert, M, Scheres, H.W.
Deposit date:2019-02-07
Release date:2019-03-27
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Novel tau filament fold in chronic traumatic encephalopathy encloses hydrophobic molecules.
Nature, 568, 2019
6HRE
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Paired helical filament from sporadic Alzheimer's disease brain
Descriptor: Microtubule-associated protein tau
Authors:Falcon, B, Zhang, W, Schweighauser, M, Murzin, A.G, Vidal, R, Garringer, H.J, Ghetti, B, Scheres, S.H.W, Goedert, M.
Deposit date:2018-09-26
Release date:2018-10-10
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Tau filaments from multiple cases of sporadic and inherited Alzheimer's disease adopt a common fold.
Acta Neuropathol., 136, 2018
6HRF
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Straight filament from sporadic Alzheimer's disease brain
Descriptor: Microtubule-associated protein tau
Authors:Falcon, B, Zhang, W, Schweighauser, M, Murzin, A.G, Vidal, R, Garringer, H.J, Ghetti, B, Scheres, S.H.W, Goedert, M.
Deposit date:2018-09-26
Release date:2018-10-10
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Tau filaments from multiple cases of sporadic and inherited Alzheimer's disease adopt a common fold.
Acta Neuropathol., 136, 2018
5O3L
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Paired helical filament in Alzheimer's disease brain
Descriptor: Microtubule-associated protein tau
Authors:Fitzpatrick, A.W.P, Falcon, B, He, S, Murzin, A.G, Murshudov, G, Garringer, H.G, Crowther, R.A, Ghetti, B, Goedert, M, Scheres, S.H.W.
Deposit date:2017-05-24
Release date:2017-07-26
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Cryo-EM structures of tau filaments from Alzheimer's disease.
Nature, 547, 2017
5O3O
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Pronase-treated paired helical filament in Alzheimer's disease brain
Descriptor: Microtubule-associated protein tau
Authors:Fitzpatrick, A.W.P, Falcon, B, He, S, Murzin, A.G, Murshudov, G, Garringer, H.G, Crowther, R.A, Ghetti, B, Goedert, M, Scheres, S.H.W.
Deposit date:2017-05-24
Release date:2017-07-26
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Cryo-EM structures of tau filaments from Alzheimer's disease.
Nature, 547, 2017
5O3T
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Straight filament in Alzheimer's disease brain
Descriptor: Microtubule-associated protein tau
Authors:Fitzpatrick, A.W.P, Falcon, B, He, S, Murzin, A.G, Murshudov, G, Garringer, H.G, Crowther, R.A, Ghetti, B, Goedert, M, Scheres, S.H.W.
Deposit date:2017-05-24
Release date:2017-07-26
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Cryo-EM structures of tau filaments from Alzheimer's disease.
Nature, 547, 2017
1AP0
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BU of 1ap0 by Molmil
STRUCTURE OF THE CHROMATIN BINDING (CHROMO) DOMAIN FROM MOUSE MODIFIER PROTEIN 1, NMR, 26 STRUCTURES
Descriptor: MODIFIER PROTEIN 1
Authors:Ball, L.J, Murzina, N.V, Broadhurst, R.W, Raine, A.R.C, Archer, S.J, Stott, F.J, Murzin, A.G, Singh, P.B, Domaille, P.J, Laue, E.D.
Deposit date:1997-07-22
Release date:1998-07-22
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structure of the chromatin binding (chromo) domain from mouse modifier protein 1.
EMBO J., 16, 1997
1OI1
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BU of 1oi1 by Molmil
Crystal Structure of the MBT domains of Human SCML2
Descriptor: DI(HYDROXYETHYL)ETHER, SCML2 PROTEIN
Authors:Sathyamurthy, A, Allen, M.D, Murzin, A.G, Bycroft, M.
Deposit date:2003-06-04
Release date:2003-06-15
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Crystal Structure of the Malignant Brain Tumor (Mbt) Repeats in Sex Comb on Midleg-Like 2 (Scml2).
J.Biol.Chem., 278, 2003
6TJO
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BU of 6tjo by Molmil
Cryo-EM structure of TypeI tau filaments extracted from the brains of individuals with Corticobasal degeneration
Descriptor: Microtubule-associated protein tau
Authors:Zhang, W, Murzin, A.G, Falcon, B, Shi, Y, Goedert, M, Scheres, S.H.W.
Deposit date:2019-11-26
Release date:2020-02-05
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Novel tau filament fold in corticobasal degeneration.
Nature, 580, 2020
6TJX
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BU of 6tjx by Molmil
Cryo-EM structure of TypeII tau filaments extracted from the brains of individuals with Corticobasal degeneration
Descriptor: Microtubule-associated protein tau
Authors:Zhang, W, Murzin, A.G, Falcon, B, Shi, Y, Goedert, M, Scheres, S.H.W.
Deposit date:2019-11-27
Release date:2020-02-05
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Novel tau filament fold in corticobasal degeneration.
Nature, 580, 2020
2W6K
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The crystal structure at 1.7 A resolution of CobE, a protein from the cobalamin (vitamin B12) biosynthetic pathway
Descriptor: COBE, GLYCEROL, SULFATE ION
Authors:Vevodova, J, Smith, D, McGoldrick, H, Deery, E, Murzin, A.G, Warren, M.J, Wilson, K.S.
Deposit date:2008-12-18
Release date:2008-12-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The Crystal Structure at 1.7 A Resolution of Cobe, a Protein from the Cobalamin (Vitamin B12) Biosynthetic Pathway
To be Published
2W6L
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BU of 2w6l by Molmil
The crystal structure at 1.7 A resolution of CobE, a protein from the cobalamin (vitamin B12) biosynthetic pathway
Descriptor: COBE, GLYCEROL, SULFATE ION
Authors:Vevodova, J, Smith, D, McGoldrick, H, Deery, E, Murzin, A.G, Warren, M.J, Wilson, K.S.
Deposit date:2008-12-18
Release date:2008-12-30
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:The Crystal Structure at 1.7 A Resolution of Cobe, a Protein from the Cobalamin (Vitamin B12) Biosynthetic Pathway
To be Published
6XYP
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BU of 6xyp by Molmil
Multiple system atrophy Type II-1 alpha-synuclein filament
Descriptor: Alpha-synuclein
Authors:Schweighauser, M, Shi, Y, Tarutani, A, Kametani, F, Murzin, A.G, Ghetti, B, Matsubara, T, Tomita, T, Ando, T, Hasegawa, K, Murayama, S, Yoshida, M, Hasegawa, M, Scheres, S.H.W, Goedert, M.
Deposit date:2020-01-30
Release date:2020-02-12
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.29 Å)
Cite:Structures of alpha-synuclein filaments from multiple system atrophy.
Nature, 585, 2020
6XYQ
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Multiple system atrophy Type II-2 alpha-synuclein filament
Descriptor: Alpha-synuclein
Authors:Schweighauser, M, Shi, Y, Tarutani, A, Kametani, F, Murzin, A.G, Ghetti, B, Matsubara, T, Tomita, T, Ando, T, Hasegawa, K, Murayama, S, Yoshida, M, Hasegawa, M, Scheres, S.H.W, Goedert, M.
Deposit date:2020-01-30
Release date:2020-02-12
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.09 Å)
Cite:Structures of alpha-synuclein filaments from multiple system atrophy.
Nature, 585, 2020
6XYO
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BU of 6xyo by Molmil
Multiple system atrophy Type I alpha-synuclein filament
Descriptor: Alpha-synuclein
Authors:Schweighauser, M, Shi, Y, Tarutani, A, Kametani, F, Murzin, A.G, Ghetti, B, Matsubara, T, Tomita, T, Ando, T, Hasegawa, K, Murayama, S, Yoshida, M, Hasegawa, M, Scheres, S.H.W, Goedert, M.
Deposit date:2020-01-30
Release date:2020-02-12
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Structures of alpha-synuclein filaments from multiple system atrophy.
Nature, 585, 2020
9GG0
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P301L tau filaments from human brain
Descriptor: Isoform Tau-D of Microtubule-associated protein tau
Authors:Schweighauser, M, Shi, Y, Murzin, A.G, Garringer, H.J, Vidal, R, Murrell, J.R, Erro, M.E, Seelaar, H, Ferrer, I, van Swieten, J.C, Ghetti, B, Scheres, S.H.W, Goedert, M.
Deposit date:2024-08-12
Release date:2024-09-11
Method:ELECTRON MICROSCOPY (2.81 Å)
Cite:Novel tau filament folds in individuals with MAPT mutations P301L and P301T.
Biorxiv, 2024
9GG1
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P301T type I tau filaments from human brain
Descriptor: Isoform Tau-D of Microtubule-associated protein tau
Authors:Schweighauser, M, Shi, Y, Murzin, A.G, Garringer, H.J, Vidal, R, Murrell, J.R, Erro, M.E, Seelaar, H, Ferrer, I, van Swieten, J.C, Ghetti, B, Scheres, S.H.W, Goedert, M.
Deposit date:2024-08-12
Release date:2024-09-11
Method:ELECTRON MICROSCOPY (2.26 Å)
Cite:Novel tau filament folds in individuals with MAPT mutations P301L and P301T.
Biorxiv, 2024
9GG6
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P301T type II tau filaments from human brain
Descriptor: Isoform Tau-F of Microtubule-associated protein tau
Authors:Schweighauser, M, Shi, Y, Murzin, A.G, Garringer, H.J, Vidal, R, Murrell, J.R, Erro, M.E, Seelaar, H, Ferrer, I, van Swieten, J.C, Ghetti, B, Scheres, S.H.W, Goedert, M.
Deposit date:2024-08-13
Release date:2024-09-11
Method:ELECTRON MICROSCOPY (3.36 Å)
Cite:Novel tau filament folds in individuals with MAPT mutations P301L and P301T.
Biorxiv, 2024

 

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