4S0F
 
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4RY2
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8FD9
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3BIK
 | | Crystal Structure of the PD-1/PD-L1 Complex | | Descriptor: | GLYCEROL, Programmed cell death 1 ligand 1, Programmed cell death protein 1 | | Authors: | Lin, D.Y, Tanaka, Y, Iwasaki, M, Gittis, A.G, Su, H.P, Mikami, B, Okazaki, T, Honjo, T, Minato, N, Garboczi, D.N. | | Deposit date: | 2007-11-30 | | Release date: | 2008-02-26 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | The PD-1/PD-L1 complex resembles the antigen-binding Fv domains of antibodies and T cell receptors.
Proc.Natl.Acad.Sci.Usa, 105, 2008
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3BIS
 | | Crystal Structure of the PD-L1 | | Descriptor: | Programmed cell death 1 ligand 1 | | Authors: | Lin, D.Y, Tanaka, Y, Iwasaki, M, Gittis, A.G, Su, H.P, Mikami, B, Okazaki, T, Honjo, T, Minato, N, Garboczi, D.N. | | Deposit date: | 2007-11-30 | | Release date: | 2008-02-26 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.64 Å) | | Cite: | The PD-1/PD-L1 complex resembles the antigen-binding Fv domains of antibodies and T cell receptors.
Proc.Natl.Acad.Sci.Usa, 105, 2008
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8S93
 | | Crystal structure of the PH-TH/kinase complex of Bruton's tyrosine kinase | | Descriptor: | 2-[3'-(hydroxymethyl)-1-methyl-5-({5-[(2S)-2-methyl-4-(oxetan-3-yl)piperazin-1-yl]pyridin-2-yl}amino)-6-oxo[1,6-dihydro[3,4'-bipyridine]]-2'-yl]-7,7-dimethyl-3,4,7,8-tetrahydro-2H-cyclopenta[4,5]pyrrolo[1,2-a]pyrazin-1(6H)-one, GLYCEROL, Tyrosine-protein kinase BTK, ... | | Authors: | Lin, D.Y, Andreotti, A.H. | | Deposit date: | 2023-03-27 | | Release date: | 2023-08-16 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Conformational heterogeneity of the BTK PHTH domain drives multiple regulatory states.
Elife, 12, 2024
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8S9F
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1IG6
 | | HUMAN MRF-2 DOMAIN, NMR, 11 STRUCTURES | | Descriptor: | MODULATOR RECOGNITION FACTOR 2 | | Authors: | Lin, D, Tsui, V, Case, D, Yuan, Y.C, Chen, Y. | | Deposit date: | 2001-04-17 | | Release date: | 2001-04-25 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | HUMAN MRF-2 DOMAIN, NMR, 11 STRUCTURES
To be Published
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3NB2
 | | Crystal structure of E. coli O157:H7 effector protein NleL | | Descriptor: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, ... | | Authors: | Lin, D.Y, Chen, J. | | Deposit date: | 2010-06-02 | | Release date: | 2010-10-27 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Biochemical and Structural Studies of a HECT-like Ubiquitin Ligase from Escherichia coli O157:H7.
J.Biol.Chem., 286, 2011
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3SQV
 | | Crystal Structure of E. coli O157:H7 E3 ubiquitin ligase, NleL, with a human E2, UbcH7 | | Descriptor: | GLYCEROL, SULFATE ION, Ubiquitin-conjugating enzyme E2 L3, ... | | Authors: | Lin, D.Y, Chen, J. | | Deposit date: | 2011-07-06 | | Release date: | 2012-01-25 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Crystal structures of two bacterial HECT-like E3 ligases in complex with a human E2 reveal atomic details of pathogen-host interactions.
Proc.Natl.Acad.Sci.USA, 109, 2012
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3NAW
 | | Crystal structure of E. coli O157:H7 effector protein NleL | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, SULFATE ION, ... | | Authors: | Lin, D.Y, Chen, J. | | Deposit date: | 2010-06-02 | | Release date: | 2010-10-27 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Biochemical and Structural Studies of a HECT-like Ubiquitin Ligase from Escherichia coli O157:H7.
J.Biol.Chem., 286, 2011
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5HB0
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5HB8
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6B4I
 | | Crystal structure of human Gle1 CTD-Nup42 GBM-DDX19B(ADP) complex | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent RNA helicase DDX19B, Nucleoporin GLE1, ... | | Authors: | Lin, D.H, Correia, A.R, Cai, S.W, Huber, F.M, Jette, C.A, Hoelz, A. | | Deposit date: | 2017-09-26 | | Release date: | 2018-06-20 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (3.619 Å) | | Cite: | Structural and functional analysis of mRNA export regulation by the nuclear pore complex.
Nat Commun, 9, 2018
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6B4G
 | | Crystal structure of Chaetomium thermophilum Gle1 CTD-Nup42 GBM complex | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Nucleoporin AMO1, Nucleoporin GLE1 | | Authors: | Lin, D.H, Correia, A.R, Cai, S.W, Huber, F.M, Jette, C.A, Hoelz, A. | | Deposit date: | 2017-09-26 | | Release date: | 2018-06-20 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.648 Å) | | Cite: | Structural and functional analysis of mRNA export regulation by the nuclear pore complex.
Nat Commun, 9, 2018
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5HAX
 | | Crystal structure of Chaetomium thermophilum Nup170 NTD-Nup53 complex | | Descriptor: | 1,2-ETHANEDIOL, GLYCEROL, Nucleoporin NUP170, ... | | Authors: | Lin, D.H, Mobbs, G, Hoelz, A. | | Deposit date: | 2015-12-31 | | Release date: | 2016-04-20 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Architecture of the symmetric core of the nuclear pore.
Science, 352, 2016
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6B4F
 | | Crystal structure of human Gle1 CTD-Nup42 GBM complex | | Descriptor: | CHLORIDE ION, Nucleoporin GLE1, Nucleoporin like 2, ... | | Authors: | Lin, D.H, Correia, A.R, Cai, S.W, Huber, F.M, Jette, C.A, Hoelz, A. | | Deposit date: | 2017-09-26 | | Release date: | 2018-06-20 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.811 Å) | | Cite: | Structural and functional analysis of mRNA export regulation by the nuclear pore complex.
Nat Commun, 9, 2018
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6B4K
 | | Crystal structure of human DDX19B(AMPPNP) | | Descriptor: | ATP-dependent RNA helicase DDX19B, MAGNESIUM ION, MALONATE ION, ... | | Authors: | Lin, D.H, Correia, A.R, Cai, S.W, Huber, F.M, Jette, C.A, Hoelz, A. | | Deposit date: | 2017-09-26 | | Release date: | 2018-06-20 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structural and functional analysis of mRNA export regulation by the nuclear pore complex.
Nat Commun, 9, 2018
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6B4H
 | | Crystal structure of Chaetomium thermophilum Gle1 CTD-Nup42 GBM-IP6 complex | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, INOSITOL HEXAKISPHOSPHATE, Nucleoporin AMO1, ... | | Authors: | Lin, D.H, Correia, A.R, Cai, S.W, Huber, F.M, Jette, C.A, Hoelz, A. | | Deposit date: | 2017-09-26 | | Release date: | 2018-06-20 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.17 Å) | | Cite: | Structural and functional analysis of mRNA export regulation by the nuclear pore complex.
Nat Commun, 9, 2018
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6B4E
 | | Crystal structure of Saccharomyces cerevisiae Gle1 CTD-Nup42 GBM complex | | Descriptor: | 1,2-ETHANEDIOL, Nucleoporin GLE1, Nucleoporin NUP42, ... | | Authors: | Lin, D.H, Correia, A.R, Cai, S.W, Huber, F.M, Jette, C.A, Hoelz, A. | | Deposit date: | 2017-09-26 | | Release date: | 2018-06-20 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Structural and functional analysis of mRNA export regulation by the nuclear pore complex.
Nat Commun, 9, 2018
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6B4J
 | | Crystal structure of human Gle1 CTD-Nup42 GBM-DDX19B(AMPPNP) complex | | Descriptor: | ATP-dependent RNA helicase DDX19B, MAGNESIUM ION, Nucleoporin GLE1, ... | | Authors: | Lin, D.H, Correia, A.R, Cai, S.W, Huber, F.M, Jette, C.A, Hoelz, A. | | Deposit date: | 2017-09-26 | | Release date: | 2018-06-20 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (3.4 Å) | | Cite: | Structural and functional analysis of mRNA export regulation by the nuclear pore complex.
Nat Commun, 9, 2018
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4I9Y
 | | Structure of the C-terminal domain of Nup358 | | Descriptor: | CHLORIDE ION, E3 SUMO-protein ligase RanBP2, GLYCEROL, ... | | Authors: | Lin, D.H, Zimmermann, S, Stuwe, T, Stuwe, E, Hoelz, A. | | Deposit date: | 2012-12-05 | | Release date: | 2013-01-30 | | Last modified: | 2017-11-15 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Structural and Functional Analysis of the C-Terminal Domain of Nup358/RanBP2.
J.Mol.Biol., 425, 2013
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5HB6
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5HB7
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5HAY
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