3SQV
Crystal Structure of E. coli O157:H7 E3 ubiquitin ligase, NleL, with a human E2, UbcH7
Summary for 3SQV
Entry DOI | 10.2210/pdb3sqv/pdb |
Descriptor | secreted effector protein, Ubiquitin-conjugating enzyme E2 L3, SULFATE ION, ... (5 entities in total) |
Functional Keywords | effector protein, pentapeptide, hect domain, hect e3 ubiquitin ligase, e2 ubiquitin conjugating enzyme, protein-protein complex, ubiquitin transfer, ubiquitin, ubiquitination, ligase-signaling protein complex, ligase/signaling protein |
Biological source | Escherichia coli More |
Cellular location | Nucleus: P68036 |
Total number of polymer chains | 4 |
Total formula weight | 176608.76 |
Authors | |
Primary citation | Lin, D.Y.,Diao, J.,Chen, J. Crystal structures of two bacterial HECT-like E3 ligases in complex with a human E2 reveal atomic details of pathogen-host interactions. Proc.Natl.Acad.Sci.USA, 109:1925-1930, 2012 Cited by PubMed: 22308380DOI: 10.1073/pnas.1115025109 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.3 Å) |
Structure validation
Download full validation report