Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 72 results

1HYJ
DownloadVisualize
BU of 1hyj by Molmil
SOLUTION STRUCTURE OF THE EEA1 FYVE DOMAIN
Descriptor: ENDOSOME-ASSOCIATED PROTEIN, ZINC ION
Authors:Kutateladze, T, Overduin, M.
Deposit date:2001-01-19
Release date:2001-03-14
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Structural mechanism of endosome docking by the FYVE domain.
Science, 291, 2001
1HYI
DownloadVisualize
BU of 1hyi by Molmil
SOLUTION STRUCTURE OF THE EEA1 FYVE DOMAIN COMPLEXED WITH INOSITOL 1,3-BISPHOSPHATE
Descriptor: ENDOSOME-ASSOCIATED PROTEIN, PHOSPHORIC ACID MONO-(2,3,4,6-TETRAHYDROXY-5-PHOSPHONOOXY-CYCLOHEXYL) ESTER, ZINC ION
Authors:Kutateladze, T, Overduin, M.
Deposit date:2001-01-19
Release date:2001-03-14
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Structural mechanism of endosome docking by the FYVE domain.
Science, 291, 2001
4X34
DownloadVisualize
BU of 4x34 by Molmil
Crystal structure of the 53BP1 tandem tudor domain in complex with p53K381acK382me2
Descriptor: THR-SER-ARG-HIS-ALY-MLY-LEU-MET-PHE-LYS, Tumor suppressor p53-binding protein 1
Authors:Tong, Q, Kutateladze, T.G.
Deposit date:2014-11-27
Release date:2015-03-04
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.801 Å)
Cite:An Acetyl-Methyl Switch Drives a Conformational Change in p53.
Structure, 23, 2015
8GE0
DownloadVisualize
BU of 8ge0 by Molmil
Crystal structure of JADE1 PZP domain in complex with Histone H3
Descriptor: Histone H3.1,Protein Jade-1, ZINC ION
Authors:Klein, B.J, Liu, J, Kutateladze, T.G.
Deposit date:2023-03-06
Release date:2024-03-13
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Guiding the HBO1 complex function through the JADE subunit.
Nat.Struct.Mol.Biol., 2024
8F5Q
DownloadVisualize
BU of 8f5q by Molmil
Crystal structure of human PCNA in complex with the PIP box of FBH1
Descriptor: F-box DNA helicase 1, Proliferating cell nuclear antigen
Authors:Liu, J, Chaves-Arquero, B, Wei, P, Tencer, H, Zhang, G, Blanco, F, Kutateladze, T.
Deposit date:2022-11-15
Release date:2023-09-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Molecular insight into the PCNA-binding mode of FBH1.
Structure, 31, 2023
8GDX
DownloadVisualize
BU of 8gdx by Molmil
Crystal structure of JADE1 PZP domain
Descriptor: GLYCEROL, Protein Jade-1, ZINC ION
Authors:Klein, B.J, Liu, J, Kutateladze, T.G.
Deposit date:2023-03-06
Release date:2024-03-13
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.74 Å)
Cite:Guiding the HBO1 complex function through the JADE subunit.
Nat.Struct.Mol.Biol., 2024
7RGW
DownloadVisualize
BU of 7rgw by Molmil
Crystal structure of HERC2 DOC domain
Descriptor: DI(HYDROXYETHYL)ETHER, E3 ubiquitin-protein ligase HERC2
Authors:Liu, J, Tencer, A.H, Kutateladze, T.G.
Deposit date:2021-07-15
Release date:2022-07-20
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:The ZZ domain of HERC2 is a receptor of arginylated substrates.
Sci Rep, 12, 2022
6X7D
DownloadVisualize
BU of 6x7d by Molmil
BRD4 Bromodomain 1 in complex with multi-action inhibitor SF2523P
Descriptor: 3-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-(piperazin-1-yl)-7H-thieno[3,2-b]pyran-7-one, Bromodomain-containing protein 4
Authors:Vann, K.R, Kutateladze, T.G.
Deposit date:2020-05-29
Release date:2020-08-05
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Design of thienopyranone-based BET inhibitors that bind multiple synthetic lethality targets.
Sci Rep, 10, 2020
6U04
DownloadVisualize
BU of 6u04 by Molmil
Crystal structure of human BRPF1 PZP bound to histone H3 tail
Descriptor: Histone H3.3,BRPF1, Peregrin, PRASEODYMIUM ION, ...
Authors:Klein, B.J, Kutateladze, T.G.
Deposit date:2019-08-13
Release date:2019-11-27
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Molecular Basis for the PZP Domain of BRPF1 Association with Chromatin.
Structure, 28, 2020
7UHE
DownloadVisualize
BU of 7uhe by Molmil
Taf14 ET domain in complex with C-terminal tail of Taf2
Descriptor: C-terminal tail of Transcription initiation factor TFIID subunit 2, Transcription initiation factor TFIID subunit 14
Authors:Klein, B.J, Kutateladze, T.G.
Deposit date:2022-03-26
Release date:2022-08-17
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Taf2 mediates DNA binding of Taf14.
Nat Commun, 13, 2022
3LH0
DownloadVisualize
BU of 3lh0 by Molmil
Crystal structure of the 53BP1 tandem tudor domain in complex with p53K372me2
Descriptor: DIMETHYLATED p53 LYSINE 372 PEPTIDE, SULFATE ION, TRIETHYLENE GLYCOL, ...
Authors:Roy, S, Kutateladze, T.G.
Deposit date:2010-01-21
Release date:2010-03-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural insight into p53 recognition by the 53BP1 tandem Tudor domain.
J.Mol.Biol., 398, 2010
3C6W
DownloadVisualize
BU of 3c6w by Molmil
Crystal structure of the ING5 PHD finger in complex with H3K4me3 peptide
Descriptor: H3K4me3 histone peptide, Inhibitor of growth protein 5, ZINC ION
Authors:Champagne, K.S, Pena, P.V, Johnson, K, Kutateladze, T.G.
Deposit date:2008-02-05
Release date:2008-06-03
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:The crystal structure of the ING5 PHD finger in complex with an H3K4me3 histone peptide.
Proteins, 72, 2008
7LKY
DownloadVisualize
BU of 7lky by Molmil
Crystal Structure of PHF1 Tudor domain in complex with a peptidomimetic ligand UNC6641
Descriptor: DIMETHYL SULFOXIDE, Isoform 1 of PHD finger protein 1, Peptidomimetic inhibitor UNC6641, ...
Authors:Liu, J, Kutateladze, T.G.
Deposit date:2021-02-03
Release date:2021-12-15
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Discovery of an H3K36me3-Derived Peptidomimetic Ligand with Enhanced Affinity for Plant Homeodomain Finger Protein 1 (PHF1).
J.Med.Chem., 64, 2021
7W9V
DownloadVisualize
BU of 7w9v by Molmil
Cryo-EM structure of nucleosome in complex with p300 acetyltransferase catalytic core (complex I)
Descriptor: DNA (145-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ...
Authors:Hatazawa, S, Liu, J, Takizawa, Y, Zandian, M, Negishi, L, Kutateladze, T.G, Kurumizaka, H.
Deposit date:2021-12-10
Release date:2022-07-13
Method:ELECTRON MICROSCOPY (3.95 Å)
Cite:Structural basis for binding diversity of acetyltransferase p300 to the nucleosome.
Iscience, 25, 2022
7TRL
DownloadVisualize
BU of 7trl by Molmil
Crystal structure of human BIRC2 BIR3 domain in complex with histone H3
Descriptor: 1,2-ETHANEDIOL, Baculoviral IAP repeat-containing protein 2, Histone H3, ...
Authors:Klein, B.J, Tencer, A.H, Kutateladze, T.G.
Deposit date:2022-01-29
Release date:2023-08-02
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Molecular basis for nuclear accumulation and targeting of the inhibitor of apoptosis BIRC2.
Nat.Struct.Mol.Biol., 30, 2023
7TRM
DownloadVisualize
BU of 7trm by Molmil
Crystal structure of human BIRC2 BIR3 domain in complex with inhibitor LCL-161
Descriptor: 1,2-ETHANEDIOL, Baculoviral IAP repeat-containing protein 2, LCL-161, ...
Authors:Tencer, A.H, Klein, B.J, Kutateladze, T.G.
Deposit date:2022-01-29
Release date:2023-08-02
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Molecular basis for nuclear accumulation and targeting of the inhibitor of apoptosis BIRC2.
Nat.Struct.Mol.Biol., 30, 2023
7K7T
DownloadVisualize
BU of 7k7t by Molmil
Crystal structure of human MORC4 ATPase-CW in complex with AMPPNP
Descriptor: Isoform 3 of MORC family CW-type zinc finger protein 4, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Klein, B.J, Tencer, A.H, Kutateladze, T.G.
Deposit date:2020-09-24
Release date:2020-11-11
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.94 Å)
Cite:Molecular mechanism of the MORC4 ATPase activation.
Nat Commun, 11, 2020
4HCZ
DownloadVisualize
BU of 4hcz by Molmil
PHF1 Tudor in complex with H3K36me3
Descriptor: H3L-like histone, PHD finger protein 1
Authors:Musselman, C.A, Roy, S, Nunez, J, Kutateladze, T.G.
Deposit date:2012-10-01
Release date:2012-11-14
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Molecular basis for H3K36me3 recognition by the Tudor domain of PHF1.
Nat.Struct.Mol.Biol., 19, 2012
1R48
DownloadVisualize
BU of 1r48 by Molmil
Solution structure of the C-terminal cytoplasmic domain residues 468-497 of Escherichia coli protein ProP
Descriptor: Proline/betaine transporter
Authors:Zoetewey, D.L, Tripet, B.P, Kutateladze, T.G, Overduin, M.J, Wood, J.M, Hodges, R.S.
Deposit date:2003-10-03
Release date:2003-12-23
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Solution Structure of the C-terminal Antiparallel Coiled-coil Domain from Escherichia coli Osmosensor ProP.
J.Mol.Biol., 334, 2003
3RCP
DownloadVisualize
BU of 3rcp by Molmil
Crystal structure of the FAPP1 pleckstrin homology domain
Descriptor: GLYCEROL, Pleckstrin homology domain-containing family A member 3
Authors:Roy, S, He, J, Kutateladze, T.G.
Deposit date:2011-03-31
Release date:2011-04-20
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Molecular Basis of Phosphatidylinositol 4-Phosphate and ARF1 GTPase Recognition by the FAPP1 Pleckstrin Homology (PH) Domain.
J.Biol.Chem., 286, 2011
6AXJ
DownloadVisualize
BU of 6axj by Molmil
Crystal structure of the Yaf9 YEATS domain bound to H3K27ac
Descriptor: ALY-SER-ALA-PRO-ALA, GLYCEROL, Protein AF-9 homolog, ...
Authors:Klein, B.J, Kutateladze, T.G.
Deposit date:2017-09-06
Release date:2017-11-22
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.379 Å)
Cite:Yaf9 subunit of the NuA4 and SWR1 complexes targets histone H3K27ac through its YEATS domain.
Nucleic Acids Res., 46, 2018
7MJU
DownloadVisualize
BU of 7mju by Molmil
Crystal structure of human AF10 PZP bound to histone H3 tail
Descriptor: Histone H3.1,Protein AF-10, ZINC ION
Authors:Klein, B.J, Kutateladze, T.G.
Deposit date:2021-04-20
Release date:2021-08-04
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The role of the PZP domain of AF10 in acute leukemia driven by AF10 translocations.
Nat Commun, 12, 2021
7TV0
DownloadVisualize
BU of 7tv0 by Molmil
Crystal structure of BRD4 bromodomain 1 in complex with dual-acetylated SARS-CoV-2 E
Descriptor: Bromodomain-containing protein 4, Envelope small membrane protein
Authors:Vann, K.R, Holt, T.A, Kutateladze, T.G.
Deposit date:2022-02-03
Release date:2022-07-06
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Binding of the SARS-CoV-2 envelope E protein to human BRD4 is essential for infection.
Structure, 30, 2022
7TUQ
DownloadVisualize
BU of 7tuq by Molmil
Crystal structure of BRD4 bromodomain 1 in complex with monoacetylated SARS-CoV-2 E
Descriptor: Bromodomain-containing protein 4, Envelope small membrane protein
Authors:Vann, K.R, Kutateladze, T.G.
Deposit date:2022-02-03
Release date:2022-07-06
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.68 Å)
Cite:Binding of the SARS-CoV-2 envelope E protein to human BRD4 is essential for infection.
Structure, 30, 2022
6OIE
DownloadVisualize
BU of 6oie by Molmil
The double PHD finger (DPF) of MORF in complex with histone H3K14cr
Descriptor: Histone H3.1t peptide, Histone acetyltransferase KAT6B, ZINC ION
Authors:Klein, B.J, Kutateladze, T.G.
Deposit date:2019-04-09
Release date:2019-11-20
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.075 Å)
Cite:Histone H3K23-specific acetylation by MORF is coupled to H3K14 acylation.
Nat Commun, 10, 2019

 

123>

218853

PDB entries from 2024-04-24

PDB statisticsPDBj update infoContact PDBjnumon