3LH0
Crystal structure of the 53BP1 tandem tudor domain in complex with p53K372me2
Summary for 3LH0
Entry DOI | 10.2210/pdb3lh0/pdb |
Related | 3LGF 3LGL |
Descriptor | Tumor suppressor p53-binding protein 1, DIMETHYLATED p53 LYSINE 372 PEPTIDE, TRIETHYLENE GLYCOL, ... (5 entities in total) |
Functional Keywords | tandem tudor domain, dimethylated p53 peptide, dna repair, cell cycle, dna damage, dna-binding, methylation, transcription, transcription regulation |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus: Q12888 |
Total number of polymer chains | 2 |
Total formula weight | 15657.67 |
Authors | Roy, S.,Kutateladze, T.G. (deposition date: 2010-01-21, release date: 2010-03-23, Last modification date: 2023-09-06) |
Primary citation | Roy, S.,Musselman, C.A.,Kachirskaia, I.,Hayashi, R.,Glass, K.C.,Nix, J.C.,Gozani, O.,Appella, E.,Kutateladze, T.G. Structural insight into p53 recognition by the 53BP1 tandem Tudor domain. J.Mol.Biol., 398:489-496, 2010 Cited by PubMed: 20307547DOI: 10.1016/j.jmb.2010.03.024 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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