1HQ5
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![BU of 1hq5 by Molmil](/molmil-images/mine/1hq5) | CRYSTAL STRUCTURE OF THE BINUCLEAR MANGANESE METALLOENZYME ARGINASE COMPLEXED WITH S-(2-BORONOETHYL)-L-CYSTEINE, AN L-ARGININE ANALOGUE | Descriptor: | ARGINASE 1, MANGANESE (II) ION, S-2-(BORONOETHYL)-L-CYSTEINE | Authors: | Kim, N.N, Cox, J.D, Baggio, R.F, Emig, F.A, Mistry, S.K, Harper, S.L, Speicher, D.W, Morris Jr, S.M, Ash, D.E, Traish, A, Christianson, D.W. | Deposit date: | 2000-12-14 | Release date: | 2001-04-04 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Probing erectile function: S-(2-boronoethyl)-L-cysteine binds to arginase as a transition state analogue and enhances smooth muscle relaxation in human penile corpus cavernosum. Biochemistry, 40, 2001
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2K95
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![BU of 2k95 by Molmil](/molmil-images/mine/2k95) | Solution structure of the wild-type P2B-P3 pseudoknot of human telomerase RNA | Descriptor: | Telomerase RNA P2b-P3 pseudoknot | Authors: | Kim, N.-K, Zhang, Q, Zhou, J, Theimer, C.A, Peterson, R.D, Feigon, J. | Deposit date: | 2008-09-29 | Release date: | 2008-11-25 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution Structure and Dynamics of the Wild-type Pseudoknot of Human Telomerase RNA. J.Mol.Biol., 384, 2008
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2K96
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![BU of 2k96 by Molmil](/molmil-images/mine/2k96) | Solution structure of the RDC-refined P2B-P3 pseudoknot from human telomerase RNA (delta U177) | Descriptor: | TELOMERASE RNA P2B-P3 PSEUDOKNOT | Authors: | Kim, N.-K, Zhang, Q, Zhou, J, Theimer, C.A, Peterson, R.D, Feigon, J. | Deposit date: | 2008-09-29 | Release date: | 2008-11-25 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution Structure and Dynamics of the Wild-type Pseudoknot of Human Telomerase RNA. J.Mol.Biol., 384, 2008
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2KYE
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![BU of 2kye by Molmil](/molmil-images/mine/2kye) | Solution structure of the pseudouridine modified P6.1 hairpin of human telomerase RNA | Descriptor: | RNA (5'-R(*GP*AP*GP*AP*GP*(PSU)P*(PSU)P*GP*GP*GP*CP*(PSU)P*CP*(PSU)P*C)-3') | Authors: | Kim, N.-K, Theimer, C.A, Mitchell, J.R, Collins, K, Feigon, J. | Deposit date: | 2010-05-25 | Release date: | 2010-06-30 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Effect of pseudouridylation on the structure and activity of the catalytically essential P6.1 hairpin in human telomerase RNA. Nucleic Acids Res., 38, 2010
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2MHI
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![BU of 2mhi by Molmil](/molmil-images/mine/2mhi) | |
6LAC
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![BU of 6lac by Molmil](/molmil-images/mine/6lac) | The structural basis of the beta-carbonic anhydrase CafD (C39A mutant) of the filamentous fungus Aspergillus fumigatus | Descriptor: | Carbonic anhydrase, ZINC ION | Authors: | Jiin, M.S, Kim, S, Kim, N.J, Hong, S, Kim, S, Sung, J. | Deposit date: | 2019-11-12 | Release date: | 2019-11-27 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | The structural analysis of non-catalytic zinc binding site in the minor beta-carbonic anhydrase CafD To be published
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1WZ9
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![BU of 1wz9 by Molmil](/molmil-images/mine/1wz9) | The 2.1 A structure of a tumour suppressing serpin | Descriptor: | Maspin precursor, SULFATE ION | Authors: | Law, R.H, Irving, J.A, Buckle, A.M, Ruzyla, K, Buzza, M, Bashtannyk-Puhalovich, T.A, Beddoe, T.C, Kim, N, Worrall, D.M, Bottomley, S.P, Bird, P.I, Rossjohn, J, Whisstock, J.C. | Deposit date: | 2005-03-03 | Release date: | 2005-03-15 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The high resolution crystal structure of the human tumor suppressor maspin reveals a novel conformational switch in the G-helix. J.Biol.Chem., 280, 2005
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8JZJ
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![BU of 8jzj by Molmil](/molmil-images/mine/8jzj) | E.coli Glyceraldehyde-3-phosphate dehydrogenase structure under cryoprotect condition of ammonium sulfate | Descriptor: | Glyceraldehyde-3-phosphate dehydrogenase, SULFATE ION | Authors: | Jang, K, Hlaing, S.H.S, Kim, H.G, Kim, N, Choe, H.W, Kim, Y.J. | Deposit date: | 2023-07-05 | Release date: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | E.coli Glyceraldehyde-3-phosphate dehydrogenase structure under cryoprotect condition of ammonium sulfate To Be Published
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5HKN
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![BU of 5hkn by Molmil](/molmil-images/mine/5hkn) | Crystal structure de novo designed fullerene organizing protein complex with fullerene | Descriptor: | (C_{60}-I_{h})[5,6]fullerene, fullerene organizing protein | Authors: | Paul, J, Acharya, R, Kim, K.-H, Kim, Y.H, Kim, N.H, Grigoryan, G, DeGardo, W.F. | Deposit date: | 2016-01-14 | Release date: | 2016-05-04 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.761 Å) | Cite: | Protein-directed self-assembly of a fullerene crystal. Nat Commun, 7, 2016
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5ET3
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![BU of 5et3 by Molmil](/molmil-images/mine/5et3) | Crystal Structure of De novo Designed Fullerene organizing peptide | Descriptor: | (C_{60}-I_{h})[5,6]fullerene, Fullerene Organizing Protein (C60Sol-COP-3) | Authors: | Kim, K.-H, Kim, Y.H, Acharya, R, Kim, N.H, Paul, J, Grigoryan, G, DeGrado, W.F. | Deposit date: | 2015-11-17 | Release date: | 2016-05-04 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.671 Å) | Cite: | Protein-directed self-assembly of a fullerene crystal. Nat Commun, 7, 2016
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4M6R
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![BU of 4m6r by Molmil](/molmil-images/mine/4m6r) | Structural and biochemical basis for the inhibition of cell death by APIP, a methionine salvage enzyme | Descriptor: | Methylthioribulose-1-phosphate dehydratase, ZINC ION | Authors: | Kang, W, Hong, S.H, Lee, H.M, Kim, N.Y, Lim, Y.C, Le, L.T.M, Lim, B, Kim, H.C, Kim, T.Y, Ashida, H, Yokota, A, Hah, S.S, Chun, K.H, Jung, Y.K, Yang, J.K. | Deposit date: | 2013-08-10 | Release date: | 2014-01-29 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural and biochemical basis for the inhibition of cell death by APIP, a methionine salvage enzyme. Proc.Natl.Acad.Sci.USA, 111, 2014
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6JQE
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![BU of 6jqe by Molmil](/molmil-images/mine/6jqe) | The structural basis of the beta-carbonic anhydrases CafD (wild type) of the filamentous fungus Aspergillus fumigatus | Descriptor: | Carbonic anhydrase, ZINC ION | Authors: | Jin, M.S, Kim, S, Kim, N.J, Hong, S, Kim, S, Sung, J. | Deposit date: | 2019-03-30 | Release date: | 2019-08-14 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The structural basis of the low catalytic activities of the two minor beta-carbonic anhydrases of the filamentous fungus Aspergillus fumigatus. J.Struct.Biol., 208, 2019
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6JQC
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![BU of 6jqc by Molmil](/molmil-images/mine/6jqc) | The structural basis of the beta-carbonic anhydrase CafC (wild type) of the filamentous fungus Aspergillus fumigatus | Descriptor: | Carbonic anhydrase, ZINC ION | Authors: | Jin, M.S, Kim, S, Kim, N.J, Hong, S, Kim, S, Sung, J. | Deposit date: | 2019-03-30 | Release date: | 2019-08-14 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The structural basis of the low catalytic activities of the two minor beta-carbonic anhydrases of the filamentous fungus Aspergillus fumigatus. J.Struct.Biol., 208, 2019
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6JQD
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![BU of 6jqd by Molmil](/molmil-images/mine/6jqd) | The structural basis of the beta-carbonic anhydrase CafC (L25G and L78G mutant) of the filamentous fungus Aspergillus fumigatus | Descriptor: | Carbonic anhydrase, ZINC ION | Authors: | Jin, M.S, Kim, S, Kim, N.J, Hong, S, Kim, S, Sung, J. | Deposit date: | 2019-03-30 | Release date: | 2019-08-14 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | The structural basis of the low catalytic activities of the two minor beta-carbonic anhydrases of the filamentous fungus Aspergillus fumigatus. J.Struct.Biol., 208, 2019
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7DNZ
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![BU of 7dnz by Molmil](/molmil-images/mine/7dnz) | Cryo-EM structure of the human ABCB6 (Hemin and GSH-bound) | Descriptor: | ATP-binding cassette sub-family B member 6, mitochondrial, CHOLESTEROL HEMISUCCINATE, ... | Authors: | Kim, S, Lee, S.S, Park, J.G, Kim, J.W, Kim, S, Kim, N.J, Hong, S, Kang, J.Y, Jin, M.S. | Deposit date: | 2020-12-11 | Release date: | 2022-06-22 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structural Insights into Porphyrin Recognition by the Human ATP-Binding Cassette Transporter ABCB6. Mol.Cells, 45, 2022
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7DNY
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![BU of 7dny by Molmil](/molmil-images/mine/7dny) | Cryo-EM structure of the human ABCB6 (coproporphyrin III-bound) | Descriptor: | ATP-binding cassette sub-family B member 6, mitochondrial, CHOLESTEROL HEMISUCCINATE, ... | Authors: | Kim, S, Lee, S.S, Park, J.G, Kim, J.W, Kim, S, Kim, N.J, Hong, S, Kang, J.Y, Jin, M.S. | Deposit date: | 2020-12-11 | Release date: | 2022-06-22 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural Insights into Porphyrin Recognition by the Human ATP-Binding Cassette Transporter ABCB6. Mol.Cells, 45, 2022
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6LAI
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![BU of 6lai by Molmil](/molmil-images/mine/6lai) | The structural basis of the beta-carbonic anhydrase CafD (E54A mutant) of the filamentous fungus Aspergillus fumigatus | Descriptor: | Carbonic anhydrase, ZINC ION | Authors: | Jin, M.S, Kim, S, Kim, N.J, Hong, S, Kim, S, Sung, J. | Deposit date: | 2019-11-12 | Release date: | 2019-11-27 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | The structural analysis of non-catalytic zinc binding site in the minor beta-carbonic anhydrase CafD To be published
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7CHT
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![BU of 7cht by Molmil](/molmil-images/mine/7cht) | Crystal structure of TTK kinase domain in complex with compound 30 | Descriptor: | 2-[[2-methoxy-4-(2-oxidanylidenepyrrolidin-1-yl)phenyl]amino]-4-(oxan-4-ylamino)-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile, Dual specificity protein kinase TTK, MAGNESIUM ION | Authors: | Kim, H.L, Cho, H.Y, Park, Y.W, Lee, Y.H, Ko, E.H, Choi, H.G, Son, J.B, Kim, N.D. | Deposit date: | 2020-07-06 | Release date: | 2021-05-12 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | X-ray Crystal Structure-Guided Design and Optimization of 7 H -Pyrrolo[2,3- d ]pyrimidine-5-carbonitrile Scaffold as a Potent and Orally Active Monopolar Spindle 1 Inhibitor. J.Med.Chem., 64, 2021
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7CHM
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![BU of 7chm by Molmil](/molmil-images/mine/7chm) | Crystal structure of TTK kinase domain in complex with compound 8 | Descriptor: | 4-(cyclohexylamino)-2-[(2-methoxy-4-morpholin-4-ylcarbonyl-phenyl)amino]-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile, Dual specificity protein kinase TTK | Authors: | Kim, H.L, Cho, H.Y, Park, Y.W, Lee, Y.H, Son, J.B, Ko, E.H, Choi, H.G, Kim, N.D. | Deposit date: | 2020-07-06 | Release date: | 2021-05-12 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | X-ray Crystal Structure-Guided Design and Optimization of 7 H -Pyrrolo[2,3- d ]pyrimidine-5-carbonitrile Scaffold as a Potent and Orally Active Monopolar Spindle 1 Inhibitor. J.Med.Chem., 64, 2021
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7CHN
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![BU of 7chn by Molmil](/molmil-images/mine/7chn) | Crystal structure of TTK kinase domain in complex with compound 9 | Descriptor: | 4-(cyclohexylamino)-2-[[2-methoxy-4-(2-oxidanylidenepyrrolidin-1-yl)phenyl]amino]-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile, Dual specificity protein kinase TTK | Authors: | Kim, H.L, Cho, H.Y, Park, Y.W, Lee, Y.H, Son, J.B, Ko, E.H, Choi, H.G, Kim, N.D. | Deposit date: | 2020-07-06 | Release date: | 2021-05-12 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | X-ray Crystal Structure-Guided Design and Optimization of 7 H -Pyrrolo[2,3- d ]pyrimidine-5-carbonitrile Scaffold as a Potent and Orally Active Monopolar Spindle 1 Inhibitor. J.Med.Chem., 64, 2021
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7CLH
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![BU of 7clh by Molmil](/molmil-images/mine/7clh) | Crystal structure of TTK kinase domain in complex with compound 19 | Descriptor: | 2-[[2-methoxy-4-(2-oxidanylidenepyrrolidin-1-yl)phenyl]amino]-4-(methylamino)-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile, Dual specificity protein kinase TTK | Authors: | Kim, H.L, Cho, H.Y, Park, Y.W, Lee, Y.H, Son, J.B, Ko, E.H, Choi, H.G, Kim, N.D. | Deposit date: | 2020-07-21 | Release date: | 2021-05-12 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | X-ray Crystal Structure-Guided Design and Optimization of 7 H -Pyrrolo[2,3- d ]pyrimidine-5-carbonitrile Scaffold as a Potent and Orally Active Monopolar Spindle 1 Inhibitor. J.Med.Chem., 64, 2021
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7CJA
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![BU of 7cja by Molmil](/molmil-images/mine/7cja) | Crystal structure of TTK kinase domain in complex with compound 28 | Descriptor: | 4-(cyclopentylmethylamino)-2-[[2-methoxy-4-(2-oxidanylidenepyrrolidin-1-yl)phenyl]amino]-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile, Dual specificity protein kinase TTK | Authors: | Kim, H.L, Cho, H.Y, Park, Y.W, Lee, Y.H, Son, J.B, Ko, E.H, Choi, H.G, Kim, N.D. | Deposit date: | 2020-07-09 | Release date: | 2021-05-12 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.49 Å) | Cite: | X-ray Crystal Structure-Guided Design and Optimization of 7 H -Pyrrolo[2,3- d ]pyrimidine-5-carbonitrile Scaffold as a Potent and Orally Active Monopolar Spindle 1 Inhibitor. J.Med.Chem., 64, 2021
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7CIL
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![BU of 7cil by Molmil](/molmil-images/mine/7cil) | Crystal structure of TTK kinase domain in complex with compound 7 | Descriptor: | 4-(cyclohexylamino)-2-[(1-methylpyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile, Dual specificity protein kinase TTK | Authors: | Kim, H.L, Cho, H.Y, Park, Y.W, Lee, Y.H, Son, J.B, Ko, E.H, Choi, H.G, Kim, N.D. | Deposit date: | 2020-07-07 | Release date: | 2021-05-12 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | X-ray Crystal Structure-Guided Design and Optimization of 7 H -Pyrrolo[2,3- d ]pyrimidine-5-carbonitrile Scaffold as a Potent and Orally Active Monopolar Spindle 1 Inhibitor. J.Med.Chem., 64, 2021
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1PQ3
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![BU of 1pq3 by Molmil](/molmil-images/mine/1pq3) | Human Arginase II: Crystal Structure and Physiological Role in Male and Female Sexual Arousal | Descriptor: | Arginase II, mitochondrial precursor, CHLORIDE ION, ... | Authors: | Cama, E, Colleluori, D.M, Emig, F.A, Shin, H, Kim, S.W, Kim, N.N, Traish, A.M, Ash, D.E, Christianson, D.W. | Deposit date: | 2003-06-17 | Release date: | 2003-08-12 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Human Arginase II: Crystal Structure and Physiological Role in Male and Female Sexual Arousal Biochemistry, 42, 2003
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7XX9
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![BU of 7xx9 by Molmil](/molmil-images/mine/7xx9) | |