2DX5
 
 | | The complex structure between the mouse EAP45-GLUE domain and ubiquitin | | Descriptor: | Ubiquitin, Vacuolar protein sorting protein 36 | | Authors: | Hirano, S, Suzuki, N, Slagsvold, T, Kawasaki, M, Trambaiolo, D, Kato, R, Stenmark, H, Wakatsuki, S. | | Deposit date: | 2006-08-24 | | Release date: | 2006-10-10 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (3.35 Å) | | Cite: | Structural basis of ubiquitin recognition by mammalian Eap45 GLUE domain
Nat.Struct.Mol.Biol., 13, 2006
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2D3G
 | | Double sided ubiquitin binding of Hrs-UIM | | Descriptor: | ubiquitin, ubiquitin interacting motif from hepatocyte growth factor-regulated tyrosine kinase substrate | | Authors: | Hirano, S, Kawasaki, M, Kato, R, Wakatsuki, S. | | Deposit date: | 2005-09-28 | | Release date: | 2005-12-20 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Double-sided ubiquitin binding of Hrs-UIM in endosomal protein sorting
Nat.Struct.Mol.Biol., 13, 2006
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2ZF4
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2ZF3
 | | Crystal Structure of VioE | | Descriptor: | Hypothetical protein VioE | | Authors: | Hirano, S, Shiro, Y, Nagano, S. | | Deposit date: | 2007-12-20 | | Release date: | 2008-01-01 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal structure of VioE, a key player in the construction of the molecular skeleton of violacein
To be Published
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5B2T
 | | Crystal structure of the Streptococcus pyogenes Cas9 VRER variant in complex with sgRNA and target DNA (TGCG PAM) | | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, CRISPR-associated endonuclease Cas9, ... | | Authors: | Hirano, S, Nishimasu, H, Ishitani, R, Nureki, O. | | Deposit date: | 2016-02-02 | | Release date: | 2016-03-23 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structural Basis for the Altered PAM Specificities of Engineered CRISPR-Cas9
Mol.Cell, 61, 2016
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5B2S
 | | Crystal structure of the Streptococcus pyogenes Cas9 EQR variant in complex with sgRNA and target DNA (TGAG PAM) | | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, CRISPR-associated endonuclease Cas9, ... | | Authors: | Hirano, S, Nishimasu, H, Ishitani, R, Nureki, O. | | Deposit date: | 2016-02-02 | | Release date: | 2016-03-23 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structural Basis for the Altered PAM Specificities of Engineered CRISPR-Cas9
Mol.Cell, 61, 2016
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5B2R
 | | Crystal structure of the Streptococcus pyogenes Cas9 VQR variant in complex with sgRNA and target DNA (TGA PAM) | | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, CRISPR-associated endonuclease Cas9, ... | | Authors: | Hirano, S, Nishimasu, H, Ishitani, R, Nureki, O. | | Deposit date: | 2016-02-02 | | Release date: | 2016-03-23 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural Basis for the Altered PAM Specificities of Engineered CRISPR-Cas9
Mol.Cell, 61, 2016
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6IRZ
 | | Crystal structure of the zebrafish cap-specific adenosine methyltransferase bound to SAH and m7G-capped RNA | | Descriptor: | 1,2-ETHANEDIOL, 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE, PDX1 C-terminal-inhibiting factor 1, ... | | Authors: | Hirano, S, Nishimasu, H, Ishitani, R, Nureki, O. | | Deposit date: | 2018-11-15 | | Release date: | 2018-12-05 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Cap-specific terminal N 6 -methylation of RNA by an RNA polymerase II-associated methyltransferase.
Science, 363, 2019
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6IS0
 | | Crystal structure of the zebrafish cap-specific adenosine methyltransferase bound to SAH and m7G-capped RNA | | Descriptor: | 1,2-ETHANEDIOL, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE, ... | | Authors: | Hirano, S, Nishimasu, H, Ishitani, R, Nureki, O. | | Deposit date: | 2018-11-15 | | Release date: | 2018-12-05 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Cap-specific terminal N 6 -methylation of RNA by an RNA polymerase II-associated methyltransferase.
Science, 363, 2019
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6IRW
 | | Crystal structure of the human cap-specific adenosine methyltransferase bound to SAH | | Descriptor: | Phosphorylated CTD-interacting factor 1, S-ADENOSYL-L-HOMOCYSTEINE | | Authors: | Hirano, S, Nishimasu, H, Ishitani, R, Nureki, O. | | Deposit date: | 2018-11-14 | | Release date: | 2018-12-05 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Cap-specific terminal N 6 -methylation of RNA by an RNA polymerase II-associated methyltransferase.
Science, 363, 2019
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6IRY
 | | Crystal structure of the zebrafish cap-specific adenosine methyltransferase bound to SAH | | Descriptor: | 1,2-ETHANEDIOL, PDX1 C-terminal-inhibiting factor 1, S-ADENOSYL-L-HOMOCYSTEINE | | Authors: | Hirano, S, Nishimasu, H, Ishitani, R, Nureki, O. | | Deposit date: | 2018-11-14 | | Release date: | 2018-12-05 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Cap-specific terminal N 6 -methylation of RNA by an RNA polymerase II-associated methyltransferase.
Science, 363, 2019
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6IRV
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6IRX
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6JOO
 | | Crystal structure of Corynebacterium diphtheriae Cas9 in complex with sgRNA and target DNA | | Descriptor: | 1,2-ETHANEDIOL, CRISPR-associated protein,CRISPR-associated endonuclease Cas9, Guide RNA, ... | | Authors: | Hirano, S, Ishitani, R, Nishimasu, H, Nureki, O. | | Deposit date: | 2019-03-22 | | Release date: | 2019-04-17 | | Last modified: | 2019-05-15 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Structural basis for the promiscuous PAM recognition by Corynebacterium diphtheriae Cas9.
Nat Commun, 10, 2019
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6AI6
 | | Crystal structure of SpCas9-NG | | Descriptor: | 1,2-ETHANEDIOL, CRISPR-associated endonuclease Cas9/Csn1, DNA (28-MER), ... | | Authors: | Nishimasu, H, Hirano, S, Ishitani, R, Nureki, O. | | Deposit date: | 2018-08-21 | | Release date: | 2018-10-31 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Engineered CRISPR-Cas9 nuclease with expanded targeting space
Science, 361, 2018
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6AEL
 | | Crystal structure of ENPP1 in complex with 3'3'-cGAMP | | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-amino-9-[(2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-9-(6-amino-9H-purin-9-yl)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecin-2-yl]-1,9-dihydro-6H-purin-6-one, ... | | Authors: | Kato, K, Nishimasu, H, Hirano, S, Hirano, H, Ishitani, R, Nureki, O. | | Deposit date: | 2018-08-05 | | Release date: | 2019-03-06 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural insights into cGAMP degradation by Ecto-nucleotide pyrophosphatase phosphodiesterase 1.
Nat Commun, 9, 2018
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6AEK
 | | Crystal structure of ENPP1 in complex with pApG | | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-MONOPHOSPHATE, ... | | Authors: | Kato, K, Nishimasu, H, Hirano, S, Hirano, H, Ishitani, R, Nureki, O. | | Deposit date: | 2018-08-05 | | Release date: | 2019-03-06 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structural insights into cGAMP degradation by Ecto-nucleotide pyrophosphatase phosphodiesterase 1.
Nat Commun, 9, 2018
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6KR6
 | | Crystal structure of Drosophila Piwi | | Descriptor: | MERCURY (II) ION, Protein piwi, ZINC ION, ... | | Authors: | Yamaguchi, S, Oe, A, Yamashita, K, Hirano, S, Mastumoto, N, Ishitani, R, Nishimasu, H, Nureki, O. | | Deposit date: | 2019-08-21 | | Release date: | 2020-02-19 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Crystal structure of Drosophila Piwi.
Nat Commun, 11, 2020
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