Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

5B2T

Crystal structure of the Streptococcus pyogenes Cas9 VRER variant in complex with sgRNA and target DNA (TGCG PAM)

Summary for 5B2T
Entry DOI10.2210/pdb5b2t/pdb
Related5B2R 5B2S
DescriptorGuide RNA, CRISPR-associated endonuclease Cas9, Target DNA, ... (9 entities in total)
Functional Keywordscrispr-cas9, genome engineering, hydrolase-rna-dna complex, hydrolase/rna/dna
Biological sourceStreptococcus pyogenes serotype M1
More
Total number of polymer chains4
Total formula weight197056.21
Authors
Hirano, S.,Nishimasu, H.,Ishitani, R.,Nureki, O. (deposition date: 2016-02-02, release date: 2016-03-23, Last modification date: 2023-11-08)
Primary citationHirano, S.,Nishimasu, H.,Ishitani, R.,Nureki, O.
Structural Basis for the Altered PAM Specificities of Engineered CRISPR-Cas9
Mol.Cell, 61:886-894, 2016
Cited by
PubMed: 26990991
DOI: 10.1016/j.molcel.2016.02.018
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.2 Å)
Structure validation

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon