1F6A
 
 | | Structure of the human ige-fc bound to its high affinity receptor fc(epsilon)ri(alpha) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, HIGH AFFINITY IMMUNOGLOBULIN EPSILON RECEPTOR ALPHA-SUBUNIT, ... | | Authors: | Garman, S.C, Wurzburg, B.A, Tarchevskaya, S.S, Kinet, J.P, Jardetzky, T.S. | | Deposit date: | 2000-06-20 | | Release date: | 2000-07-20 | | Last modified: | 2021-11-03 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Structure of the Fc fragment of human IgE bound to its high-affinity receptor Fc (epsilon) RI (alpha).
Nature, 406, 2000
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1N1I
 | | The structure of MSP-1(19) from Plasmodium knowlesi | | Descriptor: | HISTIDINE, IMIDAZOLE, Merozoite surface protein-1 | | Authors: | Garman, S.C, Simcoke, W.N, Stowers, A.W, Garboczi, D.N. | | Deposit date: | 2002-10-17 | | Release date: | 2003-02-25 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structure of the C-terminal domains of merozoite surface protein-1 from
Plasmodium knowlesi reveals a novel histidine binding site
J.Biol.Chem., 278, 2003
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1R46
 | | Structure of human alpha-galactosidase | | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Garman, S.C, Garboczi, D.N. | | Deposit date: | 2003-10-03 | | Release date: | 2004-03-16 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (3.25 Å) | | Cite: | The molecular defect leading to Fabry disease: structure of human alpha-galactosidase
J.Mol.Biol., 337, 2004
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3G4X
 | | Crystal Structure of NiSOD Y9F mutant | | Descriptor: | CHLORIDE ION, NICKEL (II) ION, Superoxide dismutase [Ni] | | Authors: | Garman, S.C, Guce, A.I, Herbst, R.W, Bryngelson, P.A, Cabelli, D.E, Higgins, K.A, Ryan, K.C, Maroney, M.J. | | Deposit date: | 2009-02-04 | | Release date: | 2009-04-28 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.01 Å) | | Cite: | Role of conserved tyrosine residues in NiSOD catalysis: a case of convergent evolution
Biochemistry, 48, 2009
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3G4Z
 | | Crystal Structure of NiSOD Y9F mutant at 1.9 A | | Descriptor: | BROMIDE ION, NICKEL (II) ION, Superoxide dismutase [Ni] | | Authors: | Garman, S.C, Guce, A.I, Herbst, R.W, Bryngelson, P.A, Cabelli, D.E, Higgins, K.A, Ryan, K.C, Maroney, M.J. | | Deposit date: | 2009-02-04 | | Release date: | 2009-04-28 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.87 Å) | | Cite: | Role of conserved tyrosine residues in NiSOD catalysis: a case of convergent evolution
Biochemistry, 48, 2009
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3G50
 | | Crystal Structure of NiSOD D3A mutant at 1.9 A | | Descriptor: | NICKEL (II) ION, Superoxide dismutase [Ni] | | Authors: | Garman, S.C, Guce, A.I, Herbst, R.W, Bryngelson, P.A, Cabelli, D.E, Higgins, K.A, Ryan, K.C, Maroney, M.J. | | Deposit date: | 2009-02-04 | | Release date: | 2009-04-28 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Role of conserved tyrosine residues in NiSOD catalysis: a case of convergent evolution
Biochemistry, 48, 2009
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1J87
 | | HUMAN HIGH AFFINITY FC RECEPTOR FC(EPSILON)RI(ALPHA), HEXAGONAL CRYSTAL FORM 1 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, HIGH AFFINITY IMMUNOGLOBULIN EPSILON RECEPTOR ALPHA-SUBUNIT, ... | | Authors: | Garman, S.C, Sechi, S, Kinet, J.P, Jardetzky, T.S. | | Deposit date: | 2001-05-20 | | Release date: | 2001-08-29 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | The analysis of the human high affinity IgE receptor Fc epsilon Ri alpha from multiple crystal forms.
J.Mol.Biol., 311, 2001
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1J89
 | | HUMAN HIGH AFFINITY FC RECEPTOR FC(EPSILON)RI(ALPHA), TETRAGONAL CRYSTAL FORM 2 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HIGH AFFINITY IMMUNOGLOBULIN EPSILON RECEPTOR ALPHA-SUBUNIT, ... | | Authors: | Garman, S.C, Sechi, S, Kinet, J.P, Jardetzky, T.S. | | Deposit date: | 2001-05-20 | | Release date: | 2001-08-29 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (4.1 Å) | | Cite: | The analysis of the human high affinity IgE receptor Fc epsilon Ri alpha from multiple crystal forms.
J.Mol.Biol., 311, 2001
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1J88
 | | HUMAN HIGH AFFINITY FC RECEPTOR FC(EPSILON)RI(ALPHA), TETRAGONAL CRYSTAL FORM 1 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HIGH AFFINITY IMMUNOGLOBULIN EPSILON RECEPTOR ALPHA-SUBUNIT, ... | | Authors: | Garman, S.C, Sechi, S, Kinet, J.P, Jardetzky, T.S. | | Deposit date: | 2001-05-20 | | Release date: | 2001-08-29 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | The analysis of the human high affinity IgE receptor Fc epsilon Ri alpha from multiple crystal forms.
J.Mol.Biol., 311, 2001
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1J86
 | | HUMAN HIGH AFFINITY FC RECEPTOR FC(EPSILON)RI(ALPHA), MONOCLINIC CRYSTAL FORM 2 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-D-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Garman, S.C, Sechi, S, Kinet, J.P, Jardetzky, T.S. | | Deposit date: | 2001-05-20 | | Release date: | 2001-08-29 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | The analysis of the human high affinity IgE receptor Fc epsilon Ri alpha from multiple crystal forms.
J.Mol.Biol., 311, 2001
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1F2Q
 | | CRYSTAL STRUCTURE OF THE HUMAN HIGH-AFFINITY IGE RECEPTOR | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, HIGH AFFINITY IMMUNOGLOBULIN EPSILON RECEPTOR ALPHA-SUBUNIT, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | | Authors: | Garman, S.C, Kinet, J.P, Jardetzky, T.S. | | Deposit date: | 2000-05-28 | | Release date: | 2000-06-08 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystal structure of the human high-affinity IgE receptor.
Cell(Cambridge,Mass.), 95, 1998
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1KTC
 | | The Structure of alpha-N-Acetylgalactosaminidase | | Descriptor: | 2-acetamido-2-deoxy-beta-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Garman, S.C, Hannick, L, Zhu, A, Garboczi, D.N. | | Deposit date: | 2002-01-15 | | Release date: | 2002-03-15 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | The 1.9 A structure of alpha-N-acetylgalactosaminidase: molecular basis of glycosidase deficiency diseases.
Structure, 10, 2002
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1KTB
 | | The Structure of alpha-N-Acetylgalactosaminidase | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETIC ACID, ... | | Authors: | Garman, S.C, Hannick, L, Zhu, A, Garboczi, D.N. | | Deposit date: | 2002-01-15 | | Release date: | 2002-03-15 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | The 1.9 A structure of alpha-N-acetylgalactosaminidase: molecular basis of glycosidase deficiency diseases
Structure, 10, 2002
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1R47
 | | Structure of human alpha-galactosidase | | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-galactosidase A, ... | | Authors: | Garman, S.C, Garboczi, D.N. | | Deposit date: | 2003-10-03 | | Release date: | 2004-03-16 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (3.45 Å) | | Cite: | The molecular defect leading to Fabry disease: structure of human alpha-galactosidase
J.Mol.Biol., 337, 2004
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9AXG
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9AVS
 | | Human alpha-galactosidase A in complex with saposin B | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-galactosidase A, ... | | Authors: | Sawyer, T.K, Garman, S.C. | | Deposit date: | 2024-03-04 | | Release date: | 2024-04-17 | | Last modified: | 2024-04-24 | | Method: | X-RAY DIFFRACTION (3.53 Å) | | Cite: | Human Saposin B Ligand Binding and Presentation to alpha-Galactosidase A.
Biorxiv, 2024
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3TV8
 | | Pharmacological Chaperoning in Human alpha-Galactosidase | | Descriptor: | (2R,3S,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-triol, 2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-galactosidase A, ... | | Authors: | Rogich, J.J, Guce, A.I, Clark, N.E, Garman, S.C. | | Deposit date: | 2011-09-19 | | Release date: | 2012-01-04 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.639 Å) | | Cite: | The molecular basis of pharmacological chaperoning in human alpha-galactosidase
Chem.Biol., 18, 2011
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4FDJ
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4FDI
 | | The molecular basis of mucopolysaccharidosis IV A | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CITRIC ACID, ... | | Authors: | Rivera-Colon, Y, Garman, S.C. | | Deposit date: | 2012-05-28 | | Release date: | 2012-09-05 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | The Structure of Human GALNS Reveals the Molecular Basis for Mucopolysaccharidosis IV A.
J.Mol.Biol., 423, 2012
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8USO
 | | Full-length human CaMKII delta holoenzyme | | Descriptor: | MALONATE ION, calcium/calmodulin-dependent protein kinase | | Authors: | Ozden, C, Abromson, N.L, Tomchick, D.R, Stratton, M.M, Garman, S.C. | | Deposit date: | 2023-10-28 | | Release date: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Full-length human CaMKII delta holoenzyme
To be published
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6VZK
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6X5Q
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6X5G
 | | Cocrystal structure of human CaMKII-alpha (CAMK2A)kinase domain and LRRC7 inhibitory domain | | Descriptor: | BICINE, Calcium/calmodulin-dependent protein kinase type II subunit alpha, GLYCEROL, ... | | Authors: | Ozden, C, Stratton, M.M, Garman, S.C. | | Deposit date: | 2020-05-26 | | Release date: | 2020-12-23 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | CaMKII binds both substrates and activators at the active site.
Cell Rep, 40, 2022
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4NCQ
 | | Crystal structure of NiSOD H1A mutant | | Descriptor: | Superoxide dismutase [Ni] | | Authors: | Guce, A.I, Garman, S.C. | | Deposit date: | 2013-10-24 | | Release date: | 2014-12-24 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.08 Å) | | Cite: | Nickel superoxide dismutase: structural and functional roles of His1 and its H-bonding network.
Biochemistry, 54, 2015
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5JWL
 | | Factor Inhibiting HIF D201E in Complex with Zn, and Alpha-Ketoglutarate | | Descriptor: | 2-OXOGLUTARIC ACID, DI(HYDROXYETHYL)ETHER, Hypoxia-inducible factor 1-alpha inhibitor, ... | | Authors: | Taabazuing, C.Y, Garman, S.C, Eron, S, Knapp, M.J. | | Deposit date: | 2016-05-12 | | Release date: | 2017-05-17 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Factor Inhibiting HIF D201E in Complex with Zn, and Alpha-Ketoglutarate
To Be Published
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