1BCU
 
 | | ALPHA-THROMBIN COMPLEXED WITH HIRUGEN AND PROFLAVIN | | Descriptor: | ALPHA-THROMBIN, HIRUGEN, PROFLAVIN | | Authors: | Conti, E, Rivetti, C, Wonacott, A, Brick, P. | | Deposit date: | 1998-05-02 | | Release date: | 1998-10-14 | | Last modified: | 2023-08-02 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | X-ray and spectrophotometric studies of the binding of proflavin to the S1 specificity pocket of human alpha-thrombin.
FEBS Lett., 425, 1998
|
|
2FAL
 | | X-RAY CRYSTAL STRUCTURE OF FERRIC APLYSIA LIMACINA MYOGLOBIN IN DIFFERENT LIGANDED STATES | | Descriptor: | CYANIDE ION, MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE | | Authors: | Conti, E, Moser, C, Rizzi, M, Mattevi, A, Lionetti, C, Coda, A, Ascenzi, P, Brunori, M, Bolognesi, M. | | Deposit date: | 1993-06-14 | | Release date: | 1993-10-31 | | Last modified: | 2024-06-05 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | X-ray crystal structure of ferric Aplysia limacina myoglobin in different liganded states.
J.Mol.Biol., 233, 1993
|
|
2FAM
 | | X-RAY CRYSTAL STRUCTURE OF FERRIC APLYSIA LIMACINA MYOGLOBIN IN DIFFERENT LIGANDED STATES | | Descriptor: | MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE, THIOCYANATE ION | | Authors: | Conti, E, Moser, C, Rizzi, M, Mattevi, A, Lionetti, C, Coda, A, Ascenzi, P, Brunori, M, Bolognesi, M. | | Deposit date: | 1993-07-20 | | Release date: | 1993-10-31 | | Last modified: | 2024-06-05 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | X-ray crystal structure of ferric Aplysia limacina myoglobin in different liganded states.
J.Mol.Biol., 233, 1993
|
|
1BK6
 | | KARYOPHERIN ALPHA (YEAST) + SV40 T ANTIGEN NLS | | Descriptor: | KARYOPHERIN ALPHA, LARGE T ANTIGEN | | Authors: | Conti, E, Uy, M, Leighton, L, Blobel, G, Kuriyan, J. | | Deposit date: | 1998-07-14 | | Release date: | 1999-01-13 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Crystallographic analysis of the recognition of a nuclear localization signal by the nuclear import factor karyopherin alpha.
Cell(Cambridge,Mass.), 94, 1998
|
|
1AMU
 | | PHENYLALANINE ACTIVATING DOMAIN OF GRAMICIDIN SYNTHETASE 1 IN A COMPLEX WITH AMP AND PHENYLALANINE | | Descriptor: | ADENOSINE MONOPHOSPHATE, GRAMICIDIN SYNTHETASE 1, MAGNESIUM ION, ... | | Authors: | Conti, E, Stachelhaus, T, Marahiel, M.A, Brick, P. | | Deposit date: | 1997-06-18 | | Release date: | 1998-07-01 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural basis for the activation of phenylalanine in the non-ribosomal biosynthesis of gramicidin S.
EMBO J., 16, 1997
|
|
1BK5
 | | KARYOPHERIN ALPHA FROM SACCHAROMYCES CEREVISIAE | | Descriptor: | COBALT (II) ION, KARYOPHERIN ALPHA | | Authors: | Conti, E, Uy, M, Leighton, L, Blobel, G, Kuriyan, J. | | Deposit date: | 1998-07-14 | | Release date: | 1999-01-06 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystallographic analysis of the recognition of a nuclear localization signal by the nuclear import factor karyopherin alpha.
Cell(Cambridge,Mass.), 94, 1998
|
|
1EE4
 | |
1EE5
 | |
1LCI
 | | FIREFLY LUCIFERASE | | Descriptor: | LUCIFERASE | | Authors: | Conti, E, Franks, N.P, Brick, P. | | Deposit date: | 1996-06-01 | | Release date: | 1997-03-26 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal structure of firefly luciferase throws light on a superfamily of adenylate-forming enzymes.
Structure, 4, 1996
|
|
8RXB
 | |
8R8R
 | | Cryo-EM structure of the human mPSF with PAPOA C-terminus peptide (PAPOAc) | | Descriptor: | Cleavage and polyadenylation specificity factor subunit 1, Cleavage and polyadenylation specificity factor subunit 4, RNA (5'-R(P*AP*AP*UP*AP*AP*A)-3'), ... | | Authors: | Todesca, S, Sandmeir, F, Keidel, A, Conti, E. | | Deposit date: | 2023-11-29 | | Release date: | 2024-04-10 | | Method: | ELECTRON MICROSCOPY (2.79 Å) | | Cite: | Molecular basis of human polyA polymerase recruitment by mPSF.
Rna, 2024
|
|
8QCB
 | | CryoEM structure of a S. Cerevisiae Ski2387 complex in the open state | | Descriptor: | Antiviral helicase SKI2, Antiviral protein SKI8, Superkiller protein 3, ... | | Authors: | Keidel, A, Koegel, A, Reichelt, P, Kowalinski, E, Schaefer, I.B, Conti, E. | | Deposit date: | 2023-08-25 | | Release date: | 2023-11-08 | | Last modified: | 2023-11-29 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Concerted structural rearrangements enable RNA channeling into the cytoplasmic Ski238-Ski7-exosome assembly.
Mol.Cell, 83, 2023
|
|
8QCA
 | | CryoEM structure of a S. Cerevisiae Ski2387 complex in the closed state bound to RNA | | Descriptor: | Antiviral helicase SKI2, Antiviral protein SKI8, RNA (5'-R(P*UP*UP*UP*U)-3'), ... | | Authors: | Keidel, A, Koegel, A, Reichelt, P, Kowalinski, E, Schaefer, I.B, Conti, E. | | Deposit date: | 2023-08-25 | | Release date: | 2023-11-15 | | Last modified: | 2023-11-29 | | Method: | ELECTRON MICROSCOPY (2.84 Å) | | Cite: | Concerted structural rearrangements enable RNA channeling into the cytoplasmic Ski238-Ski7-exosome assembly.
Mol.Cell, 83, 2023
|
|
8Q9T
 | | CryoEM structure of a S. Cerevisiae Ski238 complex bound to RNA | | Descriptor: | Antiviral helicase SKI2, Antiviral protein SKI8, RNA (5'-R(P*UP*UP*UP*U)-3'), ... | | Authors: | Keidel, A, Koegel, A, Reichelt, P, Kowalinski, E, Schaefer, I.B, Conti, E. | | Deposit date: | 2023-08-21 | | Release date: | 2023-11-29 | | Method: | ELECTRON MICROSCOPY (2.84 Å) | | Cite: | Concerted structural rearrangements enable RNA channeling into the cytoplasmic Ski238-Ski7-exosome assembly.
Mol.Cell, 83, 2023
|
|
8QCF
 | | yeast cytoplasmic exosome-Ski2 complex degrading a RNA substrate | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Antiviral helicase SKI2, Exosome complex component CSL4, ... | | Authors: | Keidel, A, Koegel, A, Reichelt, P, Kowalinski, E, Schaefer, I.B, Conti, E. | | Deposit date: | 2023-08-25 | | Release date: | 2024-01-10 | | Method: | ELECTRON MICROSCOPY (2.55 Å) | | Cite: | Concerted structural rearrangements enable RNA channeling into the cytoplasmic Ski238-Ski7-exosome assembly.
Mol.Cell, 83, 2023
|
|
8BFH
 | | CNOT11 | | Descriptor: | CCR4-NOT transcription complex subunit 11 | | Authors: | Basquin, J, Ozgur, S, Conti, E. | | Deposit date: | 2022-10-26 | | Release date: | 2022-12-28 | | Last modified: | 2023-02-15 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | The human CNOT1-CNOT10-CNOT11 complex forms a structural platform for protein-protein interactions.
Cell Rep, 42, 2023
|
|
3ICQ
 | | Karyopherin nuclear state | | Descriptor: | Exportin-T, GTP-binding nuclear protein GSP1/CNR1, GUANOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Cook, A.G, Fukuhara, N, Jinek, M, Conti, E. | | Deposit date: | 2009-07-18 | | Release date: | 2009-08-25 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Structures of the tRNA export factor in the nuclear and cytosolic states
Nature, 461, 2009
|
|
4XR7
 | | Structure of the Saccharomyces cerevisiae PAN2-PAN3 core complex | | Descriptor: | PAB-dependent poly(A)-specific ribonuclease subunit PAN2, PAB-dependent poly(A)-specific ribonuclease subunit PAN3 | | Authors: | Schafer, I.B, Rode, M, Bonneau, F, Schussler, S, Conti, E. | | Deposit date: | 2015-01-20 | | Release date: | 2015-01-28 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (3.796 Å) | | Cite: | The structure of the Pan2-Pan3 core complex reveals cross-talk between deadenylase and pseudokinase.
Nat. Struct. Mol. Biol., 21, 2014
|
|
4WFD
 | | Structure of the Rrp6-Rrp47-Mtr4 interaction | | Descriptor: | ATP-dependent RNA helicase DOB1, Exosome complex exonuclease RRP6, Exosome complex protein LRP1, ... | | Authors: | Schuch, B, Conti, E. | | Deposit date: | 2014-09-14 | | Release date: | 2014-10-29 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | The exosome-binding factors Rrp6 and Rrp47 form a composite surface for recruiting the Mtr4 helicase.
Embo J., 33, 2014
|
|
4WFC
 | | Structure of the Rrp6-Rrp47 interaction | | Descriptor: | Exosome complex exonuclease RRP6, Exosome complex protein LRP1, SULFATE ION | | Authors: | Schuch, B, Conti, E. | | Deposit date: | 2014-09-14 | | Release date: | 2014-10-29 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | The exosome-binding factors Rrp6 and Rrp47 form a composite surface for recruiting the Mtr4 helicase.
Embo J., 33, 2014
|
|
4UM2
 | | Crystal structure of the TPR domain of SMG6 | | Descriptor: | GLYCEROL, TELOMERASE-BINDING PROTEIN EST1A | | Authors: | Chakrabarti, S, Bonneau, F, Schuessler, S, Eppinger, E, Conti, E. | | Deposit date: | 2014-05-14 | | Release date: | 2014-07-23 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Phospho-Dependent and Phospho-Independent Interactions of the Helicase Upf1 with the Nmd Factors Smg5-Smg7 and Smg6.
Nucleic Acids Res., 42, 2014
|
|
3N89
 | | KH domains | | Descriptor: | Defective in germ line development protein 3, isoform a | | Authors: | Nakel, K, Hartung, S.A, Bonneau, F, Eckmann, C.R, Conti, E. | | Deposit date: | 2010-05-28 | | Release date: | 2010-09-22 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.789 Å) | | Cite: | Four KH domains of the C. elegans Bicaudal-C ortholog GLD-3 form a globular structural platform.
Rna, 16, 2010
|
|
1BA3
 | | FIREFLY LUCIFERASE IN COMPLEX WITH BROMOFORM | | Descriptor: | LUCIFERASE, TRIBROMOMETHANE | | Authors: | Franks, N.P, Jenkins, A, Conti, E, Lieb, W.R, Brick, P. | | Deposit date: | 1998-04-21 | | Release date: | 1998-11-11 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structural basis for the inhibition of firefly luciferase by a general anesthetic.
Biophys.J., 75, 1998
|
|
6FT6
 | | Structure of the Nop53 pre-60S particle bound to the exosome nuclear cofactors | | Descriptor: | 25S ribosomal RNA, 5S ribosomal RNA, 60S ribosomal protein L11-A, ... | | Authors: | Schuller, J.M, Falk, S, Conti, E. | | Deposit date: | 2018-02-20 | | Release date: | 2018-03-28 | | Last modified: | 2019-12-11 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Structure of the nuclear exosome captured on a maturing preribosome.
Science, 360, 2018
|
|
6FSZ
 | | Structure of the nuclear RNA exosome | | Descriptor: | ATP-dependent RNA helicase DOB1, Exosome complex component CSL4, Exosome complex component MTR3, ... | | Authors: | Schuller, J.M, Falk, S, Conti, E. | | Deposit date: | 2018-02-20 | | Release date: | 2018-03-21 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (4.6 Å) | | Cite: | Structure of the nuclear exosome captured on a maturing preribosome.
Science, 360, 2018
|
|
