6LDK
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8SWB
| RNase H complex with streopure ASO and RNA | Descriptor: | DI(HYDROXYETHYL)ETHER, DNA (5'-R(*(OMC)P*(N7X)P*(T39)P*(C5L)P*(A2M))-D(P*(SC)P*(PST)P*(SC)P*AP*(SC)P*(SC)P*(RC)P*(AS)P*(SC)P*(PST))-R(P*(6OO)P*(RFJ)P*(6OO)P*(6OO)P*(6NW))-3'), GLYCEROL, ... | Authors: | Cho, Y.-J, Iwamoto, N. | Deposit date: | 2023-05-18 | Release date: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of RNase H/RNA/PS-ASO complex at an atomic level To Be Published
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4WFQ
| Crystal structure of TFIIH subunit | Descriptor: | GLYCEROL, SULFATE ION, Suppressor of stem-loop protein 1 | Authors: | Cho, Y, Kim, J.S, Lim, H.S. | Deposit date: | 2014-09-17 | Release date: | 2015-02-18 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure of the Rad3/XPD regulatory domain of Ssl1/p44 J.Biol.Chem., 290, 2015
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3JRW
| Phosphorylated BC domain of ACC2 | Descriptor: | Acetyl-CoA carboxylase 2 | Authors: | Cho, Y.S, Lee, J.I, Shin, D, Kim, H.T, Lee, T.G, Heo, Y.S. | Deposit date: | 2009-09-09 | Release date: | 2010-01-12 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Molecular mechanism for the regulation of human ACC2 through phosphorylation by AMPK Biochem.Biophys.Res.Commun., 391, 2010
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3JRX
| Crystal structure of the BC domain of ACC2 in complex with soraphen A | Descriptor: | Acetyl-CoA carboxylase 2, SORAPHEN A | Authors: | Cho, Y.S, Lee, J.I, Shin, D, Kim, H.T, Lee, T.G, Heo, Y.S. | Deposit date: | 2009-09-09 | Release date: | 2010-01-12 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Molecular mechanism for the regulation of human ACC2 through phosphorylation by AMPK. Biochem.Biophys.Res.Commun., 391, 2010
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2HJW
| Crystal Structure of the BC domain of ACC2 | Descriptor: | Acetyl-CoA carboxylase 2 | Authors: | Cho, Y.S, Lee, J.I, Shin, D, Kim, H.T, Lee, T.G, Heo, Y.S. | Deposit date: | 2006-07-02 | Release date: | 2007-07-03 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of the biotin carboxylase domain of human acetyl-CoA carboxylase 2. Proteins, 70, 2008
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4CQG
| The crystal structure of MPK38 in complex with OTSSP167, an orally- administrative MELK selective inhibitor | Descriptor: | 1-[6-(3,5-dichloro-4-hydroxyphenyl)-4-({trans-4-[(dimethylamino)methyl]cyclohexyl}amino)-1,5-naphthyridin-3-yl]ethanone, Maternal embryonic leucine zipper kinase, SULFATE ION | Authors: | Cho, Y.S, Kang, Y.J, Cho, H.S. | Deposit date: | 2014-02-17 | Release date: | 2014-07-09 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.57 Å) | Cite: | The crystal structure of MPK38 in complex with OTSSP167, an orally administrative MELK selective inhibitor. Biochem.Biophys.Res.Commun., 447, 2014
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4IKE
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6VRD
| Crystal structure of RNase H/RNA/PS-ASO complex at an atomic level | Descriptor: | DI(HYDROXYETHYL)ETHER, GLYCEROL, RNA (5'-R(*(OMC)P*(N7X)P*(T39)P*(C5L)P*(A2M))-D(P*(SC)P*(PST)P*(SC)P*(AS)P*(SC)P*(SC)P*(SC)P*(AS)P*(SC)P*(PST))-R(P*(6OO)P*(RFJ)P*(6OO)P*(6OO)P*(6NW))-3'), ... | Authors: | Cho, Y.-J, Butler, D. | Deposit date: | 2020-02-07 | Release date: | 2021-02-10 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.299 Å) | Cite: | Crystal structure of RNase H/RNA/PS-ASO complex at an atomic level To Be Published
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2ZU6
| crystal structure of the eIF4A-PDCD4 complex | Descriptor: | 1,2-ETHANEDIOL, ACETIC ACID, Eukaryotic initiation factor 4A-I, ... | Authors: | Cho, Y, Chang, J.H, Sohn, S.Y. | Deposit date: | 2008-10-13 | Release date: | 2009-02-24 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structure of the eIF4A-PDCD4 complex Proc.Natl.Acad.Sci.Usa, 106, 2009
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7F4U
| Cryo-EM structure of TELO2-TTI1-TTI2 complex | Descriptor: | TELO2-interacting protein 1 homolog, TELO2-interacting protein 2, Telomere length regulation protein TEL2 homolog | Authors: | Cho, Y, Kim, Y. | Deposit date: | 2021-06-21 | Release date: | 2022-06-22 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Structure of the Human TELO2-TTI1-TTI2 Complex. J.Mol.Biol., 434, 2022
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4JL5
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4JLD
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4JLA
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4JKY
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4JLB
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4JLP
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4JLO
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4JL6
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4JL8
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4R89
| Crystal structure of paFAN1 - 5' flap DNA complex with Manganase | Descriptor: | DNA (5'-D(P*AP*CP*CP*AP*GP*AP*CP*AP*CP*AP*CP*AP*TP*TP*C)-3'), DNA (5'-D(P*GP*AP*AP*TP*GP*TP*GP*TP*GP*TP*CP*TP*CP*AP*AP*TP*CP*CP*CP*AP*AP*C)-3'), DNA (5'-D(P*GP*TP*TP*GP*GP*GP*AP*TP*TP*G)-3'), ... | Authors: | Cho, Y, Gwon, G.H, Kim, Y.R. | Deposit date: | 2014-08-30 | Release date: | 2014-10-29 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (4.002 Å) | Cite: | Crystal structure of a Fanconi anemia-associated nuclease homolog bound to 5' flap DNA: basis of interstrand cross-link repair by FAN1 Genes Dev., 28, 2014
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4R8A
| Crystal structure of paFAN1 - 5' flap DNA complex | Descriptor: | DNA (5'-D(P*AP*CP*CP*AP*GP*AP*CP*AP*CP*AP*CP*AP*TP*TP*C)-3'), DNA (5'-D(P*GP*AP*AP*TP*GP*TP*GP*TP*GP*TP*CP*TP*CP*AP*AP*TP*CP*CP*CP*AP*A)-3'), DNA (5'-D(P*GP*TP*TP*GP*GP*GP*AP*TP*TP*G)-3'), ... | Authors: | Cho, Y, Gwon, G.H, Kim, Y.R. | Deposit date: | 2014-08-30 | Release date: | 2014-10-29 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Crystal structure of a Fanconi anemia-associated nuclease homolog bound to 5' flap DNA: basis of interstrand cross-link repair by FAN1 Genes Dev., 28, 2014
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3SR0
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3RF5
| Ancylostoma ceylanicum mif in complex with n-(2,3,4,5,6-pentafluoro-benzyl)-4-sulfamoyl-benzamide | Descriptor: | 2-[(furan-2-ylmethyl)amino]benzoic acid, ACETATE ION, IMIDAZOLE, ... | Authors: | Cho, Y, Lolis, E. | Deposit date: | 2011-04-05 | Release date: | 2011-10-12 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Drug Repositioning and Pharmacophore Identification in the Discovery of Hookworm MIF Inhibitors. Chem.Biol., 18, 2011
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5Y7G
| Crystal structure of paFAN1 bound to 1nt 5'flap DNA with gap | Descriptor: | CALCIUM ION, DNA (5'-D(P*GP*AP*AP*TP*GP*TP*GP*TP*GP*TP*CP*TP*CP*AP*AP*TP*CP*CP*CP*AP*AP*CP*TP*T)-3'), DNA (5'-D(P*GP*TP*TP*GP*GP*GP*AP*TP*TP*G)-3'), ... | Authors: | Cho, Y, Jin, H. | Deposit date: | 2017-08-17 | Release date: | 2018-03-14 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Structural mechanism of DNA interstrand cross-link unhooking by the bacterial FAN1 nuclease. J. Biol. Chem., 293, 2018
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