8SWB

RNase H complex with streopure ASO and RNA

Summary for 8SWB

• Entry DOI: 10.2210/pdb8swb/pdb
• Related: 6VRD
• Descriptor: Ribonuclease H1, RNA (5'-R(*UP*GP*GP*CP*GP*AP*GP*UP*GP*GP*GP*UP*GP*AP*GP*UP*GP*AP*GP*G)-3'), DNA (5'-R(*(OMC)P*(N7X)P*(T39)P*(C5L)P*(A2M))-D(P*(SC)P*(PST)P*(SC)P*AP*(SC)P*(SC)P*(RC)P*(AS)P*(SC)P*(PST))-R(P*(6OO)P*(RFJ)P*(6OO)P*(6OO)P*(6NW))-3'), ... (7 entities in total)
• Functional Keywords: complex of dna(aso) and rna oss stereochemistry (ps-backbone) rnase h, hydrolase-rna complex, hydrolase/rna
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 30105.17

Authors

Cho, Y.-J.,Iwamoto, N. (deposition date: 2023-05-18, release date: 2024-05-22)

• Primary citation: Iwamoto, N.,Cho, Y.-J.; Crystal structure of RNase H/RNA/PS-ASO complex at an atomic level; To Be Published,

Experimental method

X-RAY DIFFRACTION (2 Å)