Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 15 results

1MUP
DownloadVisualize
BU of 1mup by Molmil
PHEROMONE BINDING TO TWO RODENT URINARY PROTEINS REVEALED BY X-RAY CRYSTALLOGRAPHY
Descriptor: 2-(SEC-BUTYL)THIAZOLE, CADMIUM ION, MAJOR URINARY PROTEIN
Authors:Bocskei, Z, Flower, D.R, Groom, C.R, Phillips, S.E.V, North, A.C.T.
Deposit date:1992-09-21
Release date:1994-01-31
Last modified:2019-08-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Pheromone binding to two rodent urinary proteins revealed by X-ray crystallography.
Nature, 360, 1992
3OQK
DownloadVisualize
BU of 3oqk by Molmil
Crystal Structure Analysis of Renin-indole-piperazin inhibitor complexes
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-phenoxy-1-phenyl-3-(piperazin-1-ylcarbonyl)-1H-indole, GLYCEROL, ...
Authors:Bocskei, Z.
Deposit date:2010-09-03
Release date:2010-10-27
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Discovery and optimization of a new class of potent and non-chiral indole-3-carboxamide-based renin inhibitors.
Bioorg.Med.Chem.Lett., 20, 2010
3OOT
DownloadVisualize
BU of 3oot by Molmil
Crystal Structure Analysis of Renin-indole-piperazin inhibitor complexes
Descriptor: 2-(3-fluoro-2-methylbenzyl)-4-methyl-1-phenyl-3-(piperazin-1-ylcarbonyl)-1H-indol-5-ol, 2-acetamido-2-deoxy-beta-D-glucopyranose, Renin
Authors:Bocskei, Z.
Deposit date:2010-08-31
Release date:2010-10-27
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Discovery and optimization of a new class of potent and non-chiral indole-3-carboxamide-based renin inhibitors.
Bioorg.Med.Chem.Lett., 20, 2010
3OQF
DownloadVisualize
BU of 3oqf by Molmil
Crystal Structure Analysis of Renin-indole-piperazine inhibitor complexes
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-benzyl-1-phenyl-3-(piperazin-1-ylcarbonyl)-1H-indole, Renin
Authors:Bocskei, Z.
Deposit date:2010-09-03
Release date:2010-10-13
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.78 Å)
Cite:Discovery and optimization of a new class of potent and non-chiral indole-3-carboxamide-based renin inhibitors.
Bioorg.Med.Chem.Lett., 20, 2010
3SFC
DownloadVisualize
BU of 3sfc by Molmil
Structure-Based Optimization of Potent 4- and 6-Azaindole-3-Carboxamides as Renin Inhibitors
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Renin, ...
Authors:Scheiper, B, Matter, H, Steinhagen, H, Bocskei, Z, Fleury, V, McCort, G.
Deposit date:2011-06-13
Release date:2011-08-31
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure-based optimization of potent 4- and 6-azaindole-3-carboxamides as renin inhibitors.
Bioorg.Med.Chem.Lett., 21, 2011
1KDQ
DownloadVisualize
BU of 1kdq by Molmil
Crystal Structure Analysis of the Mutant S189D Rat Chymotrypsin
Descriptor: CALCIUM ION, CHYMOTRYPSIN B, B CHAIN, ...
Authors:Szabo, E, Bocskei, Z, Naray-Szabo, G, Graf, L, Venekei, I.
Deposit date:2001-11-13
Release date:2003-06-10
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Three Dimensional Structures of S189D Chymotrypsin and D189S Trypsin Mutants: The Effect of Polarity at Site 189 on a Protease-specific Stabilization of the Substrate-binding Site
J.Mol.Biol., 331, 2003
3VCM
DownloadVisualize
BU of 3vcm by Molmil
Crystal structure of human prorenin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, prorenin
Authors:Morales, R, Watier, Y, Bocskei, Z.
Deposit date:2012-01-04
Release date:2012-05-23
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.93 Å)
Cite:Human Prorenin Structure Sheds Light on a Novel Mechanism of Its Autoinhibition and on Its Non-Proteolytic Activation by the (Pro)renin Receptor.
J.Mol.Biol., 421, 2012
4BTU
DownloadVisualize
BU of 4btu by Molmil
Factor Xa in complex with the dual thrombin-FXa inhibitor 57.
Descriptor: 5-Chloro-thiophene-2-carboxylic acid [(S)-2-[2-chloro-5-fluoro-3-(2-oxo-piperidin-1-yl)-benzenesulfonylamino]-3-(4-methyl-piperazin-1-yl)-3-oxo-propyl]-amide, CALCIUM ION, COAGULATION FACTOR X HEAVY CHAIN, ...
Authors:Meneyrol, J, Follmann, M, Lassalle, G, Wehner, V, Barre, G, Rousseaux, T, Altenburger, J.M, Petit, F, Bocskei, Z, Stehlin-Gaon, C, Schreuder, H, Alet, N, Herault, J.-P, Millet, L, Dol, F, Hasbrand, C, Schaeffer, P, Sadoun, F, Klieber, S, Briot, C, Bono, F, Herbert, J.-M.
Deposit date:2013-06-19
Release date:2013-12-18
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.37 Å)
Cite:5-Chlorothiophene-2-Carboxylic Acid [(S)-2-[2-Methyl-3-(2-Oxopyrrolidin-1-Yl)Benzenesulfonylamino]-3-(4-Methylpiperazin-1-Yl)-3-Oxopropyl]Amide (Sar107375), a Selective and Potent Orally Active Dual Thrombin and Factor Xa Inhibitor.
J.Med.Chem., 56, 2013
4BTI
DownloadVisualize
BU of 4bti by Molmil
factor Xa in complex with the dual thrombin-FXa inhibitor 58.
Descriptor: 5-Chloro-thiophene-2-carboxylic acid [(S)-2-[2-difluoromethoxy-3-(2-oxo-piperidin-1-yl)-benzenesulfonylamino]-3-((S)-3-dimethylamino-pyrrolidin-1-yl)-3-oxo-propyl]-amide, CALCIUM ION, COAGULATION FACTOR X HEAVY CHAIN, ...
Authors:Meneyrol, J, Follmann, M, Lassalle, G, Wehner, V, Barre, G, Rousseaux, T, Altenburger, J.M, Petit, F, Bocskei, Z, Stehlin-Gaon, C, Schreuder, H, Alet, N, Herault, J.-P, Millet, L, Dol, F, Hasbrand, C, Schaeffer, P, Sadoun, F, Klieber, S, Briot, C, Bono, F, Herbert, J.-M.
Deposit date:2013-06-18
Release date:2013-12-25
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:5-Chlorothiophene-2-Carboxylic Acid [(S)-2-[2-Methyl-3-(2-Oxopyrrolidin-1-Yl)Benzenesulfonylamino]-3-(4-Methylpiperazin-1-Yl)-3-Oxopropyl]Amide (Sar107375), a Selective and Potent Orally Active Dual Thrombin and Factor Xa Inhibitor.
J.Med.Chem., 56, 2013
4BTT
DownloadVisualize
BU of 4btt by Molmil
factor Xa in complex with the dual thrombin-FXa inhibitor 31.
Descriptor: CALCIUM ION, COAGULATION FACTOR X, COAGULATION FACTOR X LIGHT CHAIN, ...
Authors:Meneyrol, J, Follmann, M, Lassalle, G, Wehner, V, Barre, G, Rousseaux, T, Altenburger, J.M, Petit, F, Bocskei, Z, Stehlin-Gaon, C, Schreuder, H, Alet, N, Herault, J.-P, Millet, L, Dol, F, Hasbrand, C, Schaeffer, P, Sadoun, F, Klieber, S, Briot, C, Bono, F, Herbert, J.-M.
Deposit date:2013-06-19
Release date:2013-12-18
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:5-Chlorothiophene-2-Carboxylic Acid [(S)-2-[2-Methyl-3-(2-Oxopyrrolidin-1-Yl)Benzenesulfonylamino]-3-(4-Methylpiperazin-1-Yl)-3-Oxopropyl]Amide (Sar107375), a Selective and Potent Orally Active Dual Thrombin and Factor Xa Inhibitor.
J.Med.Chem., 56, 2013
3EQ8
DownloadVisualize
BU of 3eq8 by Molmil
Prolyl oligopeptidase complexed with R-Pro-(decarboxy-Pro)-Type inhibitors
Descriptor: 1-{3-oxo-3-[(2S)-2-(pyrrolidin-1-ylcarbonyl)pyrrolidin-1-yl]propyl}-3-phenylquinoxalin-2(1H)-one, Prolyl endopeptidase
Authors:Kanai, K, Aranyi, P, Bocskei, Z, Ferenczy, G, Harmat, V, Simon, K, Naray-Szabo, G, Hermecz, I.
Deposit date:2008-09-30
Release date:2009-08-25
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.73 Å)
Cite:Prolyl oligopeptidase inhibition by N-acyl-pro-pyrrolidine-type molecules
J.Med.Chem., 51, 2008
4LOY
DownloadVisualize
BU of 4loy by Molmil
Crystal Structure Analysis of thrombin in complex with compound D57, 5-Chlorothiophene-2-carboxylic acid [(S)-2-[2-methyl-3-(2- oxopyrrolidin-1-yl)benzenesulfonylamino]-3-(4-methylpiperazin-1- yl)-3-oxopropyl]amide (SAR107375)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 5-Chloro-thiophene-2-carboxylic acid [(S)-2-[2-chloro-5-fluoro-3-(2-oxo-piperidin-1-yl)-benzenesulfonylamino]-3-(4-methyl-piperazin-1-yl)-3-oxo-propyl]-amide, Hirudin variant-2, ...
Authors:Stehlin-Gaon, C, Bocskei, Z.
Deposit date:2013-07-14
Release date:2014-06-04
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:5-Chlorothiophene-2-carboxylic acid [(S)-2-[2-methyl-3-(2-oxopyrrolidin-1-yl)benzenesulfonylamino]-3-(4-methylpiperazin-1-yl)-3-oxopropyl]amide (SAR107375), a selective and potent orally active dual thrombin and factor Xa inhibitor.
J.Med.Chem., 56, 2013
3EQ7
DownloadVisualize
BU of 3eq7 by Molmil
Prolyl oligopeptidase complexed with R-Pro-(decarboxy-Pro)-Type inhibitors
Descriptor: 2-{3-[(2S)-4,4-difluoro-2-(pyrrolidin-1-ylcarbonyl)pyrrolidin-1-yl]-3-oxopropyl}-isoindole-1,3(2H)-dione, Prolyl endopeptidase
Authors:Kanai, K, Aranyi, P, Bocskei, Z, Ferenczy, G, Harmat, V, Simon, K, Naray-Szabo, G, Hermecz, I.
Deposit date:2008-09-30
Release date:2009-08-25
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.89 Å)
Cite:Prolyl oligopeptidase inhibition by N-acyl-pro-pyrrolidine-type molecules
J.Med.Chem., 51, 2008
4LXB
DownloadVisualize
BU of 4lxb by Molmil
Crystal Structure Analysis of thrombin in complex with compound D58
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 5-Chloro-thiophene-2-carboxylic acid [(S)-2-[2-difluoromethoxy-3-(2-oxo-piperidin-1-yl)-benzenesulfonylamino]-3-((S)-3-dimethylamino-pyrrolidin-1-yl)-3-oxo-propyl]-amide, Hirudin variant-1, ...
Authors:Stehlin-Gaon, C, Bocskei, Z.
Deposit date:2013-07-29
Release date:2014-06-11
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.61 Å)
Cite:5-Chlorothiophene-2-carboxylic acid [(S)-2-[2-methyl-3-(2-oxopyrrolidin-1-yl)benzenesulfonylamino]-3-(4-methylpiperazin-1-yl)-3-oxopropyl]amide (SAR107375), a selective and potent orally active dual thrombin and factor Xa inhibitor.
J.Med.Chem., 56, 2013
3EQ9
DownloadVisualize
BU of 3eq9 by Molmil
Prolyl oligopeptidase complexed with R-Pro-(decarboxy-Pro)-Type inhibitors
Descriptor: 3-{4-oxo-4-[(2S)-2-(pyrrolidin-1-ylcarbonyl)pyrrolidin-1-yl]butyl}-5,5-diphenylimidazolidine-2,4-dione, Prolyl endopeptidase
Authors:Kanai, K, Aranyi, P, Bocskei, Z, Ferenczy, G, Harmat, V, Simon, K, Naray-Szabo, G, Hermecz, I.
Deposit date:2008-09-30
Release date:2009-08-25
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.47 Å)
Cite:Prolyl oligopeptidase inhibition by N-acyl-pro-pyrrolidine-type molecules
J.Med.Chem., 51, 2008

221051

PDB entries from 2024-06-12

PDB statisticsPDBj update infoContact PDBjnumon