6DUQ
 
 | | Structure of a Rho-NusG KOW domain complex | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ... | | Authors: | Berger, J.M, Lawson, M.R. | | Deposit date: | 2018-06-21 | | Release date: | 2018-09-05 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (3.7 Å) | | Cite: | Mechanism for the Regulated Control of Bacterial Transcription Termination by a Universal Adaptor Protein.
Mol. Cell, 71, 2018
|
|
1BGW
 | | TOPOISOMERASE RESIDUES 410-1202, | | Descriptor: | TOPOISOMERASE | | Authors: | Berger, J.M, Gamblin, S.J, Harrison, S.C, Wang, J.C. | | Deposit date: | 1996-02-20 | | Release date: | 1996-07-11 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structure and mechanism of DNA topoisomerase II.
Nature, 379, 1996
|
|
3C4P
 | | Crystal Structure of the SHV-1 Beta-lactamase/Beta-lactamase inhibitor protein (BLIP) E73M complex | | Descriptor: | Beta-lactamase SHV-1, Beta-lactamase inhibitory protein, SULFATE ION | | Authors: | Reynolds, K.A, Hanes, M.S, Thomson, J.M, Antczak, A.J, Berger, J.M, Bonomo, R.A, Kirsch, J.F, Handel, T.M. | | Deposit date: | 2008-01-30 | | Release date: | 2008-05-27 | | Last modified: | 2021-10-20 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Computational redesign of the SHV-1 beta-lactamase/beta-lactamase inhibitor protein interface.
J.Mol.Biol., 382, 2008
|
|
2G2W
 | | Crystal Structure of the SHV D104K Beta-lactamase/Beta-lactamase inhibitor protein (BLIP) complex | | Descriptor: | Beta-lactamase SHV-1, Beta-lactamase inhibitory protein | | Authors: | Reynolds, K.A, Thomson, J.M, Corbett, K.D, Bethel, C.R, Berger, J.M, Kirsch, J.F, Bonomo, R.A, Handel, T.M. | | Deposit date: | 2006-02-16 | | Release date: | 2006-07-04 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structural and Computational Characterization of the SHV-1 beta-Lactamase-beta-Lactamase Inhibitor Protein Interface.
J.Biol.Chem., 281, 2006
|
|
2G2U
 | | Crystal Structure of the SHV-1 Beta-lactamase/Beta-lactamase inhibitor protein (BLIP) complex | | Descriptor: | Beta-lactamase SHV-1, Beta-lactamase inhibitory protein | | Authors: | Reynolds, K.A, Thomson, J.M, Corbett, K.D, Bethel, C.R, Berger, J.M, Kirsch, J.F, Bonomo, R.A, Handel, T.M. | | Deposit date: | 2006-02-16 | | Release date: | 2006-07-04 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Structural and Computational Characterization of the SHV-1 beta-Lactamase-beta-Lactamase Inhibitor Protein Interface.
J.Biol.Chem., 281, 2006
|
|
1FNN
 | | CRYSTAL STRUCTURE OF CDC6P FROM PYROBACULUM AEROPHILUM | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, CELL DIVISION CONTROL PROTEIN 6, MAGNESIUM ION | | Authors: | Liu, J, Smith, C.L, DeRyckere, D, DeAngelis, K, Martin, G.S, Berger, J.M. | | Deposit date: | 2000-08-22 | | Release date: | 2000-10-04 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structure and function of Cdc6/Cdc18: implications for origin recognition and checkpoint control.
Mol.Cell, 6, 2000
|
|
4NMN
 | | Aquifex aeolicus replicative helicase (DnaB) complexed with ADP, at 3.3 resolution | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Replicative DNA helicase, ... | | Authors: | Lyubimov, A.Y, Strycharska, M.S, Erzberger, J.P, Berger, J.M. | | Deposit date: | 2013-11-15 | | Release date: | 2014-01-29 | | Method: | X-RAY DIFFRACTION (3.301 Å) | | Cite: | Nucleotide and partner-protein control of bacterial replicative helicase structure and function.
Mol.Cell, 52, 2013
|
|
2QBY
 | | Crystal structure of a heterodimer of Cdc6/Orc1 initiators bound to origin DNA (from S. solfataricus) | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Cell division control protein 6 homolog 1, Cell division control protein 6 homolog 3, ... | | Authors: | Cunningham Dueber, E.L, Corn, J.E, Bell, S.D, Berger, J.M. | | Deposit date: | 2007-06-18 | | Release date: | 2007-09-11 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (3.35 Å) | | Cite: | Replication origin recognition and deformation by a heterodimeric archaeal Orc1 complex.
Science, 317, 2007
|
|
7UGW
 | | M. tuberculosis DNA gyrase cleavage core bound to DNA and evybactin | | Descriptor: | DNA (46-MER), DNA gyrase subunit A, DNA gyrase subunit B, ... | | Authors: | Hauk, G, Imai, Y, Lewis, K, Berger, J.M. | | Deposit date: | 2022-03-25 | | Release date: | 2022-08-17 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Evybactin is a DNA gyrase inhibitor that selectively kills Mycobacterium tuberculosis.
Nat.Chem.Biol., 18, 2022
|
|
1MU5
 | | Structure of topoisomerase subunit | | Descriptor: | CALCIUM ION, Type II DNA topoisomerase VI Subunit B | | Authors: | Corbett, K.D, Berger, J.M. | | Deposit date: | 2002-09-23 | | Release date: | 2003-01-07 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structure of the topoisomerase VI-B subunit: implications for type II topoisomerase mechanism and evolution
Embo J., 22, 2003
|
|
1MX0
 | | Structure of topoisomerase subunit | | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, SODIUM ION, ... | | Authors: | Corbett, K.D, Berger, J.M. | | Deposit date: | 2002-10-01 | | Release date: | 2003-01-07 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structure of the topoisomerase VI-B subunit: implications for type II topoisomerase mechanism and evolution
Embo J., 22, 2003
|
|
4XGC
 | | Crystal structure of the eukaryotic origin recognition complex | | Descriptor: | CHLORIDE ION, Origin recognition complex subunit 1, Origin recognition complex subunit 2, ... | | Authors: | Bleichert, F, Botchan, M.R, Berger, J.M. | | Deposit date: | 2014-12-30 | | Release date: | 2015-04-01 | | Last modified: | 2019-12-04 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Crystal structure of the eukaryotic origin recognition complex.
Nature, 519, 2015
|
|
3KML
 | |
3L4J
 | | Topoisomerase II-DNA cleavage complex, apo | | Descriptor: | 3'-THIO-THYMIDINE-5'-PHOSPHATE, DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*CP*GP*TP*CP*AP*TP*CP*C)-3'), DNA (5'-D(*CP*GP*CP*GP*GP*TP*AP*GP*CP*AP*GP*TP*AP*GP*G)-3'), ... | | Authors: | Schmidt, B.H, Burgin, A.B, Deweese, J.E, Osheroff, N, Berger, J.M. | | Deposit date: | 2009-12-20 | | Release date: | 2010-05-26 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.48 Å) | | Cite: | A novel and unified two-metal mechanism for DNA cleavage by type II and IA topoisomerases.
Nature, 465, 2010
|
|
3L4K
 | | Topoisomerase II-DNA cleavage complex, metal-bound | | Descriptor: | 3'-THIO-THYMIDINE-5'-PHOSPHATE, DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*CP*GP*TP*CP*AP*TP*CP*C)-3'), DNA (5'-D(*CP*GP*CP*GP*GP*TP*AP*GP*CP*AP*GP*TP*AP*GP*G)-3'), ... | | Authors: | Schmidt, B.H, Burgin, A.B, Deweese, J.E, Osheroff, N, Berger, J.M. | | Deposit date: | 2009-12-20 | | Release date: | 2010-05-26 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.98 Å) | | Cite: | A novel and unified two-metal mechanism for DNA cleavage by type II and IA topoisomerases.
Nature, 465, 2010
|
|
3TO1
 | | Two surfaces on Rtt106 mediate histone binding and chaperone activity | | Descriptor: | Histone chaperone RTT106 | | Authors: | Zunder, R.M, Antczak, A.J, Berger, J.M, Rine, J. | | Deposit date: | 2011-09-02 | | Release date: | 2011-12-21 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Two surfaces on the histone chaperone Rtt106 mediate histone binding, replication, and silencing.
Proc.Natl.Acad.Sci.USA, 109, 2012
|
|
4WMG
 | | Structure of hen egg-white lysozyme from a microfludic harvesting device using synchrotron radiation (2.5A) | | Descriptor: | Lysozyme C | | Authors: | Lyubimov, A.Y, Murray, T.D, Koehl, A, Uervirojnangkoorn, M, Zeldin, O.B, Cohen, A.E, Soltis, S.M, Baxter, E.M, Brewster, A.S, Sauter, N.K, Brunger, A.T, Berger, J.M. | | Deposit date: | 2014-10-08 | | Release date: | 2015-04-22 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Capture and X-ray diffraction studies of protein microcrystals in a microfluidic trap array.
Acta Crystallogr.,Sect.D, 71, 2015
|
|
8TXR
 | | E. coli ExoVII(H238A) | | Descriptor: | Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease 7 small subunit | | Authors: | Liu, C, Berger, J.M. | | Deposit date: | 2023-08-24 | | Release date: | 2024-01-31 | | Last modified: | 2024-02-07 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Structure of Escherichia coli exonuclease VII.
Proc.Natl.Acad.Sci.USA, 121, 2024
|
|
3UC1
 | | Mycobacterium tuberculosis gyrase type IIA topoisomerase C-terminal domain | | Descriptor: | ACETATE ION, CALCIUM ION, DNA gyrase subunit A, ... | | Authors: | Tretter, E.M, Berger, J.M. | | Deposit date: | 2011-10-25 | | Release date: | 2012-03-28 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Mechanisms for Defining Supercoiling Set Point of DNA Gyrase Orthologs: II. THE SHAPE OF THE GyrA SUBUNIT C-TERMINAL DOMAIN (CTD) IS NOT A SOLE DETERMINANT FOR CONTROLLING SUPERCOILING EFFICIENCY.
J.Biol.Chem., 287, 2012
|
|
4FM9
 | | Human topoisomerase II alpha bound to DNA | | Descriptor: | DNA (5'-D(*CP*GP*CP*GP*CP*AP*TP*CP*GP*TP*CP*AP*TP*CP*CP*TP*C)-3'), DNA (5'-D(P*GP*AP*GP*GP*AP*TP*GP*AP*CP*GP*AP*TP*G)-3'), DNA topoisomerase 2-alpha, ... | | Authors: | Wendorff, T.J, Schmidt, B.H, Heslop, P, Austin, C.A, Berger, J.M. | | Deposit date: | 2012-06-15 | | Release date: | 2012-08-08 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.901 Å) | | Cite: | The Structure of DNA-Bound Human Topoisomerase II Alpha: Conformational Mechanisms for Coordinating Inter-Subunit Interactions with DNA Cleavage.
J.Mol.Biol., 424, 2012
|
|
4GFH
 | | Topoisomerase II-DNA-AMPPNP complex | | Descriptor: | DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*CP*GP*TP*CP*AP*TP*CP*C)-3'), DNA (5'-D(*CP*GP*CP*GP*GP*TP*AP*GP*CP*AP*GP*TP*AP*GP*G)-3'), DNA (5'-D(P*CP*CP*TP*AP*CP*TP*GP*CP*TP*AP*C)-3'), ... | | Authors: | Schmidt, B.H, Osheroff, N, Berger, J.M. | | Deposit date: | 2012-08-03 | | Release date: | 2012-10-03 | | Last modified: | 2019-07-31 | | Method: | X-RAY DIFFRACTION (4.408 Å) | | Cite: | Structure of a topoisomerase II-DNA-nucleotide complex reveals a new control mechanism for ATPase activity.
Nat.Struct.Mol.Biol., 19, 2012
|
|
3C4O
 | | Crystal Structure of the SHV-1 Beta-lactamase/Beta-lactamase inhibitor protein (BLIP) E73M/S130K/S146M complex | | Descriptor: | Beta-lactamase SHV-1, Beta-lactamase inhibitory protein, SULFATE ION | | Authors: | Reynolds, K.A, Hanes, M.S, Thomson, J.M, Antczak, A.J, Berger, J.M, Bonomo, R.A, Kirsch, J.F, Handel, T.M. | | Deposit date: | 2008-01-30 | | Release date: | 2008-05-27 | | Last modified: | 2021-10-20 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Computational redesign of the SHV-1 beta-lactamase/beta-lactamase inhibitor protein interface.
J.Mol.Biol., 382, 2008
|
|
5JJI
 | | Rho transcription termination factor bound to rU7 and 6 ADP-BeF3 molecules | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, ... | | Authors: | Thomsen, N.D, Lawson, M.R, Witkowsky, L.B, Qu, S, Berger, J.M. | | Deposit date: | 2016-04-24 | | Release date: | 2016-11-16 | | Last modified: | 2019-12-25 | | Method: | X-RAY DIFFRACTION (2.601 Å) | | Cite: | Molecular mechanisms of substrate-controlled ring dynamics and substepping in a nucleic acid-dependent hexameric motor.
Proc. Natl. Acad. Sci. U.S.A., 113, 2016
|
|
5JJL
 | | Rho transcription termination factor bound to rU8 and 5 ADP-BeF3 molecules | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ... | | Authors: | Thomsen, N.D, Lawson, M.R, Witkowsky, L.B, Qu, S, Berger, J.M. | | Deposit date: | 2016-04-24 | | Release date: | 2016-11-16 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Molecular mechanisms of substrate-controlled ring dynamics and substepping in a nucleic acid-dependent hexameric motor.
Proc. Natl. Acad. Sci. U.S.A., 113, 2016
|
|
6QEM
 | | E. coli DnaBC complex bound to ssDNA | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, DNA replication protein DnaC, MAGNESIUM ION, ... | | Authors: | Arias-Palomo, E, Puri, N, O'Shea Murray, V.L, Yan, Q, Berger, J.M. | | Deposit date: | 2019-01-08 | | Release date: | 2019-03-06 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Physical Basis for the Loading of a Bacterial Replicative Helicase onto DNA.
Mol.Cell, 74, 2019
|
|
