6EVI
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![BU of 6evi by Molmil](/molmil-images/mine/6evi) | solution NMR structure of EB1 C terminus (191-260) | Descriptor: | Microtubule-associated protein RP/EB family member 1 | Authors: | Barsukov, I.L, Almeida, T.B. | Deposit date: | 2017-11-01 | Release date: | 2018-02-07 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Targeting SxIP-EB1 interaction: An integrated approach to the discovery of small molecule modulators of dynamic binding sites. Sci Rep, 7, 2017
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6EVQ
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![BU of 6evq by Molmil](/molmil-images/mine/6evq) | |
2LNK
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![BU of 2lnk by Molmil](/molmil-images/mine/2lnk) | |
2K8G
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![BU of 2k8g by Molmil](/molmil-images/mine/2k8g) | |
7OLG
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![BU of 7olg by Molmil](/molmil-images/mine/7olg) | EB1 bound to MACF peptide | Descriptor: | 11MACF, Microtubule-associated protein RP/EB family member 1 | Authors: | Almeida, T.B, Barsukov, I.L. | Deposit date: | 2021-05-20 | Release date: | 2022-06-01 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | EB1 bound to MACF peptide To Be Published
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5G4X
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![BU of 5g4x by Molmil](/molmil-images/mine/5g4x) | The crystal structure of the SHANK3 N-terminus | Descriptor: | 1,2-ETHANEDIOL, SH3 AND MULTIPLE ANKYRIN REPEAT DOMAINS PROTEIN 3 | Authors: | Zacharchenko, T, Barsukov, I. | Deposit date: | 2016-05-17 | Release date: | 2017-01-25 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.166 Å) | Cite: | SHANK proteins limit integrin activation by directly interacting with Rap1 and R-Ras. Nat. Cell Biol., 19, 2017
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2X0C
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![BU of 2x0c by Molmil](/molmil-images/mine/2x0c) | Crystal Structure of the R7R8 domains of Talin | Descriptor: | TALIN-1 | Authors: | Gingras, A.R, Goult, B.T, Bate, N, Barsukov, I.L, Emsley, J, Critchely, D.R. | Deposit date: | 2009-12-08 | Release date: | 2010-07-07 | Last modified: | 2023-03-01 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Central Region of Talin Has a Unique Fold that Binds Vinculin and Actin. J.Biol.Chem., 285, 2010
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3C1V
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![BU of 3c1v by Molmil](/molmil-images/mine/3c1v) | |
3IVF
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![BU of 3ivf by Molmil](/molmil-images/mine/3ivf) | Crystal structure of the talin head FERM domain | Descriptor: | Talin-1 | Authors: | Elliott, P.R, Goult, B.T, Bate, N, Grossmann, J.G, Roberts, G.C.K, Critchley, D.R, Barsukov, I.L. | Deposit date: | 2009-09-01 | Release date: | 2010-08-18 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | The Structure of the talin head reveals a novel extended conformation of the FERM domain Structure, 18, 2010
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2B0H
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![BU of 2b0h by Molmil](/molmil-images/mine/2b0h) | Solution structure of VBS3 fragment of talin | Descriptor: | Talin-1 | Authors: | Gingras, A.R, Vogel, K.P, Steinhoff, H.J, Ziegler, W.H, Patel, B, Emsley, J, Critchley, D.R, Roberts, G.C, Barsukov, I.L. | Deposit date: | 2005-09-14 | Release date: | 2006-01-17 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Structural and Dynamic Characterization of a Vinculin Binding Site in the Talin Rod Biochemistry, 45, 2006
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1RE6
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![BU of 1re6 by Molmil](/molmil-images/mine/1re6) | Localisation of Dynein Light Chains 1 and 2 and their Pro-apoptotic Ligands | Descriptor: | dynein light chain 2 | Authors: | Day, C.L, Puthalakath, H, Skea, G, Strasser, A, Barsukov, I, Lian, L.Y, Huang, D.C, Hinds, M.G. | Deposit date: | 2003-11-06 | Release date: | 2004-03-23 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Localization of dynein light chains 1 and 2 and their pro-apoptotic ligands. Biochem.J., 377, 2004
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3PV1
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![BU of 3pv1 by Molmil](/molmil-images/mine/3pv1) | Crystal structure of the USP15 DUSP-UBL domains | Descriptor: | ACETATE ION, Ubiquitin carboxyl-terminal hydrolase 15 | Authors: | Elliott, P.R, Urbe, S, Clague, M.J, Barsukov, I.L. | Deposit date: | 2010-12-06 | Release date: | 2011-11-16 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural variability of the ubiquitin specific protease DUSP-UBL double domains. Febs Lett., 585, 2011
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5FZT
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![BU of 5fzt by Molmil](/molmil-images/mine/5fzt) | The crystal structure of R7R8 in complex with a DLC1 fragment. | Descriptor: | MALONATE ION, RHO GTPASE-ACTIVATING PROTEIN 7, TALIN-1 | Authors: | Zacharchenko, T, Qian, X, Goult, B.T, Jethwa, D, Almeida, T, Ballestrem, C, Critchley, D.R, Lowy, D.R, Barsukov, I.L. | Deposit date: | 2016-03-15 | Release date: | 2016-04-27 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Ld Motif Recognition by Talin: Structure of the Talin-Dlc1 Complex. Structure, 24, 2016
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2QDQ
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![BU of 2qdq by Molmil](/molmil-images/mine/2qdq) | Crystal structure of the talin dimerisation domain | Descriptor: | Talin-1 | Authors: | Gingras, A.R, Putz, N.S.M, Bate, N, Barsukov, I.L, Critchley, D.R.C. | Deposit date: | 2007-06-21 | Release date: | 2008-01-29 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The structure of the C-terminal actin-binding domain of talin. Embo J., 27, 2008
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1GRM
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![BU of 1grm by Molmil](/molmil-images/mine/1grm) | REFINEMENT OF THE SPATIAL STRUCTURE OF THE GRAMICIDIN A TRANSMEMBRANE ION-CHANNEL (RUSSIAN) | Descriptor: | GRAMICIDIN A | Authors: | Arseniev, A.S, Barsukov, I.L, Lomize, A.L, Orekhov, V.Y, Bystrov, V.F. | Deposit date: | 1993-10-18 | Release date: | 1994-01-31 | Last modified: | 2023-11-15 | Method: | SOLUTION NMR | Cite: | Refinement of the Spatial Structure of the Gramicidin a Ion Channel Biol.Membr.(Ussr), 18, 1992
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1BCT
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![BU of 1bct by Molmil](/molmil-images/mine/1bct) | |
1XWJ
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![BU of 1xwj by Molmil](/molmil-images/mine/1xwj) | Vinculin head (1-258) in complex with the talin vinculin binding site 3 (1945-1969) | Descriptor: | Talin, Vinculin | Authors: | Gingras, A.R, Papagrigoriou, E, Barsukov, I.L, Critchley, D.R, Emsley, J. | Deposit date: | 2004-11-01 | Release date: | 2005-10-11 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural and Dynamic Characterization of a Vinculin Binding Site in the Talin Rod Biochemistry, 45, 2006
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1AO8
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![BU of 1ao8 by Molmil](/molmil-images/mine/1ao8) | DIHYDROFOLATE REDUCTASE COMPLEXED WITH METHOTREXATE, NMR, 21 STRUCTURES | Descriptor: | DIHYDROFOLATE REDUCTASE, METHOTREXATE | Authors: | Gargaro, A.R, Soteriou, A, Frenkiel, T.A, Bauer, C.J, Birdsall, B, Polshakov, V.I, Barsukov, I.L, Roberts, G.C.K, Feeney, J. | Deposit date: | 1997-07-22 | Release date: | 1998-02-25 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | The solution structure of the complex of Lactobacillus casei dihydrofolate reductase with methotrexate. J.Mol.Biol., 277, 1998
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4A3P
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![BU of 4a3p by Molmil](/molmil-images/mine/4a3p) | Structure of USP15 DUSP-UBL deletion mutant | Descriptor: | ACETATE ION, IODIDE ION, UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 15 | Authors: | Elliott, P.R, Liu, H, Pastok, M.W, Grossmann, G.J, Rigden, D.J, Clague, M.J, Urbe, S, Barsukov, I.L. | Deposit date: | 2011-10-03 | Release date: | 2011-11-16 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structural Variability of the Ubiquitin Specific Protease Dusp-Ubl Double Domains. FEBS Lett., 585, 2011
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1ZW3
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![BU of 1zw3 by Molmil](/molmil-images/mine/1zw3) | Vinculin Head (0-258) in Complex with the Talin Rod residues 1630-1652 | Descriptor: | Talin 1, Vinculin | Authors: | Gingras, A.R, Ziegler, W.H, Barsukov, I.L, Roberts, G.C, Critchley, D.R, Emsley, J. | Deposit date: | 2005-06-03 | Release date: | 2005-09-20 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Mapping and consensus sequence identification for multiple vinculin binding sites within the talin rod J.Biol.Chem., 280, 2005
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1ZVZ
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![BU of 1zvz by Molmil](/molmil-images/mine/1zvz) | Vinculin Head (0-258) in Complex with the Talin Rod Residue 820-844 | Descriptor: | Talin 1, Vinculin | Authors: | Gingras, A.R, Ziegler, W.H, Barsukov, I.L, Roberts, G.C, Critchley, D.R, Emsley, J. | Deposit date: | 2005-06-03 | Release date: | 2005-09-20 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Mapping and consensus sequence identification for multiple vinculin binding sites within the talin rod J.Biol.Chem., 280, 2005
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1ZW2
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![BU of 1zw2 by Molmil](/molmil-images/mine/1zw2) | Vinculin Head (0-258) in Complex with the Talin Rod residues 2345-2369 | Descriptor: | Vinculin, talin | Authors: | Gingras, A.R, Ziegler, W.H, Barsukov, I.L, Roberts, G.C, Critchley, D.R, Emsley, J. | Deposit date: | 2005-06-03 | Release date: | 2005-09-20 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Mapping and consensus sequence identification for multiple vinculin binding sites within the talin rod J.Biol.Chem., 280, 2005
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1SJ7
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![BU of 1sj7 by Molmil](/molmil-images/mine/1sj7) | Crystal Structure of Talin Rod 482-655 | Descriptor: | PLATINUM (II) ION, Talin 1 | Authors: | Papagrigoriou, E, Gingras, A.R, Barsukov, I.L, Critchley, D.R, Emsley, J. | Deposit date: | 2004-03-03 | Release date: | 2004-08-24 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Activation of a vinculin-binding site in the talin rod involves rearrangement of a five-helix bundle EMBO J., 23, 2004
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1U89
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![BU of 1u89 by Molmil](/molmil-images/mine/1u89) | Solution structure of VBS2 fragment of talin | Descriptor: | Talin 1 | Authors: | Fillingham, I, Gingras, A.R, Papagrigoriou, E, Patel, B, Emsley, J, Roberts, G.C.K, Critchley, D.R, Barsukov, I.L. | Deposit date: | 2004-08-05 | Release date: | 2005-01-18 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | A vinculin binding domain from the talin rod unfolds to form a complex with the vinculin head. Structure, 13, 2005
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1U6H
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![BU of 1u6h by Molmil](/molmil-images/mine/1u6h) | Vinculin head (0-258) in complex with the talin vinculin binding site 2 (849-879) | Descriptor: | Talin, Vinculin | Authors: | Fillingham, I, Gingras, A.R, Papagrigoriou, E, Patel, B, Emsley, J, Roberts, G.C.K, Critchley, D.R, Barsukov, I.L. | Deposit date: | 2004-07-30 | Release date: | 2005-01-18 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.38 Å) | Cite: | A vinculin binding domain from the talin rod unfolds to form a complex with the vinculin head. Structure, 13, 2005
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