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1AO8

DIHYDROFOLATE REDUCTASE COMPLEXED WITH METHOTREXATE, NMR, 21 STRUCTURES

Summary for 1AO8
Entry DOI10.2210/pdb1ao8/pdb
DescriptorDIHYDROFOLATE REDUCTASE, METHOTREXATE (2 entities in total)
Functional Keywordsoxidoreductase, inhibitor-enzyme complex
Biological sourceLactobacillus casei
Total number of polymer chains1
Total formula weight18786.03
Authors
Gargaro, A.R.,Soteriou, A.,Frenkiel, T.A.,Bauer, C.J.,Birdsall, B.,Polshakov, V.I.,Barsukov, I.L.,Roberts, G.C.K.,Feeney, J. (deposition date: 1997-07-22, release date: 1998-02-25, Last modification date: 2022-02-16)
Primary citationGargaro, A.R.,Soteriou, A.,Frenkiel, T.A.,Bauer, C.J.,Birdsall, B.,Polshakov, V.I.,Barsukov, I.L.,Roberts, G.C.,Feeney, J.
The solution structure of the complex of Lactobacillus casei dihydrofolate reductase with methotrexate.
J.Mol.Biol., 277:119-134, 1998
Cited by
PubMed: 9514736
DOI: 10.1006/jmbi.1997.1560
PDB entries with the same primary citation
Experimental method
SOLUTION NMR
Structure validation

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