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PDB: 52 results

2FEC
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BU of 2fec by Molmil
Structure of the E203Q mutant of the Cl-/H+ exchanger CLC-ec1 from E.Coli
Descriptor: Fab fragment, heavy chain, light chain, ...
Authors:Accardi, A, Walden, M.P, Nguitragool, W, Jayaram, H, Williams, C, Miller, C.
Deposit date:2005-12-15
Release date:2006-01-03
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (3.967 Å)
Cite:Separate ion pathways in a Cl-/H+ exchanger
J.Gen.Physiol., 126, 2005
2FEE
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BU of 2fee by Molmil
Structure of the Cl-/H+ exchanger CLC-ec1 from E.Coli in NaBr
Descriptor: Fab fragment, heavy chain, light chain, ...
Authors:Accardi, A, Walden, M.P, Nguitragool, W, Jayaram, H, Williams, C, Miller, C.
Deposit date:2005-12-15
Release date:2006-01-03
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Separate ion pathways in a Cl-/H+ exchanger
J.Gen.Physiol., 126, 2005
2FED
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BU of 2fed by Molmil
Structure of the E203Q mutant of the Cl-/H+ exchanger CLC-ec1 from E.Coli
Descriptor: Fab fragment, heavy chain, light chain, ...
Authors:Accardi, A, Walden, M.P, Nguitragool, W, Jayaram, H, Williams, C, Miller, C.
Deposit date:2005-12-15
Release date:2006-01-03
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.317 Å)
Cite:Separate ion pathways in a Cl-/H+ exchanger
J.Gen.Physiol., 126, 2005
2HT2
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BU of 2ht2 by Molmil
Structure of the Escherichia coli ClC chloride channel Y445H mutant and Fab complex
Descriptor: BROMIDE ION, Fab fragment, heavy chain, ...
Authors:Accardi, A, Lobet, S, Williams, C, Miller, C, Dutzler, R.
Deposit date:2006-07-25
Release date:2006-09-19
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (3.32 Å)
Cite:Synergism Between Halide Binding and Proton Transport in a CLC-type Exchanger.
J.Mol.Biol., 362, 2006
2HLF
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BU of 2hlf by Molmil
Structure of the Escherichis coli ClC chloride channel Y445E mutant and Fab complex
Descriptor: BROMIDE ION, Fab Fragment, Heavy chain, ...
Authors:Accardi, A, Lobet, S, Williams, C, Miller, C, Dutzler, R.
Deposit date:2006-07-07
Release date:2006-09-19
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Synergism Between Halide Binding and Proton Transport in a CLC-type Exchanger
J.Mol.Biol., 362, 2006
2HT3
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BU of 2ht3 by Molmil
Structure of the Escherichia coli ClC chloride channel Y445L mutant and Fab complex
Descriptor: BROMIDE ION, Fab fragment, Heavy chain, ...
Authors:Accardi, A, Lobet, S, Williams, C, Miller, C, Dutzler, R.
Deposit date:2006-07-25
Release date:2006-09-19
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Synergism between halide binding and proton transport in a CLC-type exchanger
J.Mol.Biol., 362, 2006
2HT4
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BU of 2ht4 by Molmil
Structure of the Escherichia coli ClC chloride channel Y445W mutant and Fab complex
Descriptor: BROMIDE ION, Fab fragment, Heavy chain, ...
Authors:Accardi, A, Lobet, S, Williams, C, Miller, C, Dutzler, R.
Deposit date:2006-07-25
Release date:2006-09-19
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Synergism Between Halide Binding and Proton Transport in a CLC-type Exchanger.
J.Mol.Biol., 362, 2006
2HTL
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BU of 2htl by Molmil
Structure of the Escherichia coli ClC chloride channel Y445F mutant and Fab complex
Descriptor: BROMIDE ION, Fab fragment, Heavy chain, ...
Authors:Accardi, A, Lobet, S, Williams, C, Miller, C, Dutzler, R.
Deposit date:2006-07-26
Release date:2006-09-19
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Synergism Between Halide Binding and Proton Transport in a CLC-type Exchanger.
J.Mol.Biol., 362, 2006
2HTK
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BU of 2htk by Molmil
Structure of the Escherichia coli ClC chloride channel Y445A mutant and Fab complex
Descriptor: BROMIDE ION, Fab fragment, Heavy chain, ...
Authors:Accardi, A, Lobet, S, Williams, C, Miller, C, Dutzler, R.
Deposit date:2006-07-26
Release date:2006-09-19
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.41 Å)
Cite:Synergism between halide binding and proton transport in a CLC-type exchanger
J.Mol.Biol., 362, 2006
3DET
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BU of 3det by Molmil
Structure of the E148A, Y445A doubly ungated mutant of E.coli CLC_Ec1, Cl-/H+ antiporter
Descriptor: Fab fragment, Heavy chain, Light chain, ...
Authors:Jayaram, H, Accardi, A, Wu, F, Williams, C, Miller, C.
Deposit date:2008-06-10
Release date:2008-06-17
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Ion permeation through a Cl--selective channel designed from a CLC Cl-/H+ exchanger
Proc.Natl.Acad.Sci.USA, 105, 2008
8GA1
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BU of 8ga1 by Molmil
CLC-ec1 R230C/L249C/C85A at pH 4.5 100mM Cl Swap
Descriptor: CHLORIDE ION, H(+)/Cl(-) exchange transporter ClcA
Authors:Fortea, E, Lee, S, Argyos, Y, Chadda, R, Ciftci, D, Huysmans, G, Robertson, J.L, Boudker, O, Accardi, A.
Deposit date:2023-02-22
Release date:2024-02-07
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Structural basis of pH-dependent activation in a CLC transporter.
Nat.Struct.Mol.Biol., 31, 2024
8GA3
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BU of 8ga3 by Molmil
CLC-ec1 R230C/L249C/C85A at pH 4.5 100mM Cl Turn
Descriptor: CHLORIDE ION, H(+)/Cl(-) exchange transporter ClcA
Authors:Fortea, E, Lee, S, Argyos, Y, Chadda, R, Ciftci, D, Huysmans, G, Robertson, J.L, Boudker, O, Accardi, A.
Deposit date:2023-02-22
Release date:2024-02-07
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural basis of pH-dependent activation in a CLC transporter.
Nat.Struct.Mol.Biol., 31, 2024
8GAH
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BU of 8gah by Molmil
CLC-ec1 L25C/A450C/C85A at pH 4.5 100mM Cl Twist
Descriptor: CHLORIDE ION, H(+)/Cl(-) exchange transporter ClcA
Authors:Fortea, E, Lee, S, Argyos, Y, Chadda, R, Ciftci, D, Huysmans, G, Robertson, J.L, Boudker, O, Accardi, A.
Deposit date:2023-02-22
Release date:2024-02-07
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural basis of pH-dependent activation in a CLC transporter.
Nat.Struct.Mol.Biol., 31, 2024
8GA0
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BU of 8ga0 by Molmil
CLC-ec1 E202Y at pH 4.5 100mM Cl Turn
Descriptor: H(+)/Cl(-) exchange transporter ClcA
Authors:Fortea, E, Lee, S, Argyos, Y, Chadda, R, Ciftci, D, Huysmans, G, Robertson, J.L, Boudker, O, Accardi, A.
Deposit date:2023-02-22
Release date:2024-02-07
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural basis of pH-dependent activation in a CLC transporter.
Nat.Struct.Mol.Biol., 31, 2024
8GA5
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BU of 8ga5 by Molmil
CLC-ec1 L25C/A450C/C85A at pH 4.5 100mM Cl Intermediate
Descriptor: CHLORIDE ION, H(+)/Cl(-) exchange transporter ClcA
Authors:Fortea, E, Lee, S, Argyos, Y, Chadda, R, Ciftci, D, Huysmans, G, Robertson, J.L, Boudker, O, Accardi, A.
Deposit date:2023-02-22
Release date:2024-02-07
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Structural basis of pH-dependent activation in a CLC transporter.
Nat.Struct.Mol.Biol., 31, 2024
7N8P
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BU of 7n8p by Molmil
CLC-ec1 at pH 4.5 100mM Cl Swap
Descriptor: H(+)/Cl(-) exchange transporter ClcA
Authors:Fortea, E, Boudker, O, Accardi, A.
Deposit date:2021-06-15
Release date:2022-11-16
Method:ELECTRON MICROSCOPY (3.42 Å)
Cite:Structural basis of common gate activation in CLC transporters
To Be Published
7N9W
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BU of 7n9w by Molmil
CLC-ec1 pH 4.5 100mM Cl Twist1
Descriptor: H(+)/Cl(-) exchange transporter ClcA
Authors:Fortea, E, Boudker, O, Accardi, A.
Deposit date:2021-06-18
Release date:2022-11-16
Method:ELECTRON MICROSCOPY (4.16 Å)
Cite:Structural basis of common gate activation in CLC transporters
To Be Published
4MQX
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BU of 4mqx by Molmil
CLC-ec1 Fab Complex Cysless A399C-A432C mutant
Descriptor: CHLORIDE ION, ERIC, H(+)/Cl(-) exchange transporter ClcA, ...
Authors:Basilio, D, Noack, K, Picollo, A, Accardi, A.
Deposit date:2013-09-16
Release date:2014-04-16
Last modified:2014-05-28
Method:X-RAY DIFFRACTION (3.516 Å)
Cite:Conformational changes required for H(+)/Cl(-) exchange mediated by a CLC transporter.
Nat.Struct.Mol.Biol., 21, 2014
6E1O
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BU of 6e1o by Molmil
afTMEM16 reconstituted in nanodiscs in the presence of Ca2+ and ceramide 24:0
Descriptor: CALCIUM ION, DECANE, DODECANE, ...
Authors:Falzone, M.E, Accardi, A.
Deposit date:2018-07-10
Release date:2019-02-06
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.59 Å)
Cite:Structural basis of Ca2+-dependent activation and lipid transport by a TMEM16 scramblase.
Elife, 8, 2019
6E0H
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BU of 6e0h by Molmil
PDB: afTMEM16 reconstituted in nanodiscs in the presence of Ca2+
Descriptor: CALCIUM ION, Plasma membrane channel protein (Aqy1), putative
Authors:Falzone, M.E, Accardi, A.
Deposit date:2018-07-06
Release date:2019-02-06
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (4.05 Å)
Cite:Structural basis of Ca2+-dependent activation and lipid transport by a TMEM16 scramblase.
Elife, 8, 2019
6DZ7
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BU of 6dz7 by Molmil
afTMEM16 reconstituted in nanodiscs in the absence of Ca2+
Descriptor: Plasma membrane channel protein (Aqy1), putative
Authors:Falzone, M.E, Accardi, A.
Deposit date:2018-07-03
Release date:2019-02-06
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.89 Å)
Cite:Structural basis of Ca2+-dependent activation and lipid transport by a TMEM16 scramblase.
Elife, 8, 2019
8TPN
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BU of 8tpn by Molmil
nhTMEM16 lipid scramblase in lipid nanodiscs with MSP2N2 scaffold protein in the presence of Ca2+ (intermediate state)
Descriptor: CALCIUM ION, Lipid scramblase nhTMEM16
Authors:Feng, Z, Accardi, A.
Deposit date:2023-08-04
Release date:2024-05-08
Method:ELECTRON MICROSCOPY (4.07 Å)
Cite:Structural basis of closed groove scrambling by a TMEM16 protein.
Nat.Struct.Mol.Biol., 2024
8TPQ
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BU of 8tpq by Molmil
nhTMEM16 A444P mutant in lipid nanodiscs with MSP1E3 scaffold protein in the presence of Ca2+ (long TM6)
Descriptor: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, CALCIUM ION, Lipid scramblase nhTMEM16
Authors:Feng, Z, Accardi, A.
Deposit date:2023-08-04
Release date:2024-05-08
Method:ELECTRON MICROSCOPY (3.35 Å)
Cite:Structural basis of closed groove scrambling by a TMEM16 protein.
Nat.Struct.Mol.Biol., 2024
8TOK
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BU of 8tok by Molmil
nhTMEM16 lipid scramblase in lipid nanodiscs with MSP2N2 scaffold protein in the presence of Ca2+ (open state)
Descriptor: CALCIUM ION, Lipid scramblase nhTMEM16
Authors:Feng, Z, Accardi, A.
Deposit date:2023-08-03
Release date:2024-05-08
Method:ELECTRON MICROSCOPY (3.84 Å)
Cite:Structural basis of closed groove scrambling by a TMEM16 protein.
Nat.Struct.Mol.Biol., 2024
8TOL
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BU of 8tol by Molmil
nhTMEM16 lipid scramblase in lipid nanodiscs with MSP1E3 scaffold protein in the presence of Ca2+ (open state)
Descriptor: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, CALCIUM ION, Lipid scramblase nhTMEM16
Authors:Feng, Z, Accardi, A.
Deposit date:2023-08-03
Release date:2024-05-08
Method:ELECTRON MICROSCOPY (2.85 Å)
Cite:Structural basis of closed groove scrambling by a TMEM16 protein.
Nat.Struct.Mol.Biol., 2024

 

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