7YPH
| Open-spiral pentamer of the substrate-free Lon protease with a Y224S mutation | Descriptor: | Lon protease, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER | Authors: | Li, S, Hsieh, K.Y, Kuo, C.I, Lee, S.H, Ho, M.R, Wang, C.H, Zhang, K, Chang, C.I. | Deposit date: | 2022-08-03 | Release date: | 2023-10-25 | Last modified: | 2023-11-29 | Method: | ELECTRON MICROSCOPY (3.68 Å) | Cite: | A 5+1 assemble-to-activate mechanism of the Lon proteolytic machine. Nat Commun, 14, 2023
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7YPJ
| Spiral pentamer of the substrate-free Lon protease with a S678A mutation | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Lon protease | Authors: | Li, S, Hsieh, K.Y, Kuo, C.I, Lee, S.H, Ho, M.R, Wang, C.H, Zhang, K, Chang, C.I. | Deposit date: | 2022-08-03 | Release date: | 2023-10-25 | Last modified: | 2023-11-29 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | A 5+1 assemble-to-activate mechanism of the Lon proteolytic machine. Nat Commun, 14, 2023
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7YPI
| Spiral hexamer of the substrate-free Lon protease with a Y224S mutation | Descriptor: | Lon protease, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER | Authors: | Li, S, Hsieh, K.Y, Kuo, C.I, Lee, S.H, Ho, M.R, Wang, C.H, Zhang, K, Chang, C.I. | Deposit date: | 2022-08-03 | Release date: | 2023-10-25 | Last modified: | 2023-11-29 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | A 5+1 assemble-to-activate mechanism of the Lon proteolytic machine. Nat Commun, 14, 2023
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5AFR
| N-terminal fragment of dynein heavy chain | Descriptor: | DYNEIN HEAVY CHAIN, CYTOPLASMIC | Authors: | Urnavicius, L, Zhang, K, Diamant, A.G, Motz, C, Schlager, M.A, Yu, M, Patel, N.A, Robinson, C.V, Carter, A.P. | Deposit date: | 2015-01-23 | Release date: | 2015-02-18 | Last modified: | 2018-04-25 | Method: | X-RAY DIFFRACTION (5 Å) | Cite: | The Structure of the Dynactin Complex and its Interaction with Dynein. Science, 347, 2015
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4NSW
| Crystal structure of the BAR-PH domain of ACAP1 | Descriptor: | Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 | Authors: | Pang, X, Zhang, K, Ma, J, Zhou, Q, Sun, F. | Deposit date: | 2013-11-29 | Release date: | 2014-10-15 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | A PH Domain in ACAP1 Possesses Key Features of the BAR Domain in Promoting Membrane Curvature Dev.Cell, 31, 2014
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3QQ2
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6LS4
| A novel anti-tumor agent S-40 in complex with tubulin | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 3-[(4-cyclopropylphenyl)sulfonylamino]-4-methyl-N-(pyridin-3-ylmethyl)benzamide, GLYCEROL, ... | Authors: | Du, T, Lin, S, Ji, M, Xue, N, Liu, Y, Zhang, K, Lu, D, Chen, X, Xu, H. | Deposit date: | 2020-01-17 | Release date: | 2021-01-20 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | A novel orally active microtubule destabilizing agent S-40 targets the colchicine-binding site and shows potent antitumor activity. Cancer Lett., 495, 2020
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1N4E
| Crystal Structure of a DNA Decamer Containing a Thymine-dimer | Descriptor: | 5'-D(*CP*GP*AP*AP*TP*TP*AP*AP*GP*C)-3', 5'-D(*GP*CP*TP*TP*AP*AP*TP*TP*CP*G)-3' | Authors: | Park, H, Zhang, K, Ren, Y, Nadji, S, Sinha, N, Taylor, J.-S, Kang, C. | Deposit date: | 2002-10-30 | Release date: | 2003-02-04 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of a DNA decamer containing a cis-syn thymine dimer. Proc.Natl.Acad.Sci.USA, 99, 2002
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3TK9
| Crystal structure of human granzyme H | Descriptor: | Granzyme H, SULFATE ION | Authors: | Wang, L, Zhang, K, Wu, L, Tong, L, Sun, F, Fan, Z. | Deposit date: | 2011-08-25 | Release date: | 2011-12-28 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural insights into the substrate specificity of human granzyme H: the functional roles of a novel RKR motif J.Immunol., 188, 2012
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3TJV
| Crystal structure of human granzyme H with a peptidyl substrate | Descriptor: | Granzyme H, PTSYAGDDSG, SULFATE ION | Authors: | Wang, L, Zhang, K, Wu, L, Tong, L, Sun, F, Fan, Z. | Deposit date: | 2011-08-25 | Release date: | 2011-12-28 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural insights into the substrate specificity of human granzyme H: the functional roles of a novel RKR motif J.Immunol., 188, 2012
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3TJU
| Crystal structure of human granzyme H with an inhibitor | Descriptor: | Ac-PTSY-CMK inhibitor, Granzyme H, SULFATE ION | Authors: | Wang, L, Zhang, K, Wu, L, Tong, L, Sun, F, Fan, Z. | Deposit date: | 2011-08-25 | Release date: | 2011-12-28 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural insights into the substrate specificity of human granzyme H: the functional roles of a novel RKR motif J.Immunol., 188, 2012
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4EJR
| Crystal structure of major capsid protein S domain from rabbit hemorrhagic disease virus | Descriptor: | Major capsid protein VP60 | Authors: | Xu, F, Ma, J, Zhang, K, Wang, X, Sun, F. | Deposit date: | 2012-04-07 | Release date: | 2013-01-30 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Atomic model of rabbit hemorrhagic disease virus by cryo-electron microscopy and crystallography. Plos Pathog., 9, 2013
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4EGT
| Crystal structure of major capsid protein P domain from rabbit hemorrhagic disease virus | Descriptor: | Major capsid protein VP60 | Authors: | Wang, X, Xu, F, Zhang, K, Zhai, Y, Sun, F. | Deposit date: | 2012-04-01 | Release date: | 2013-01-30 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Atomic model of rabbit hemorrhagic disease virus by cryo-electron microscopy and crystallography. Plos Pathog., 9, 2013
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8J5Y
| Structural and mechanistic insight into ribosomal ITS2 RNA processing by nuclease-kinase machinery | Descriptor: | LAS1 isoform 1, Polynucleotide 5'-hydroxyl-kinase GRC3 | Authors: | Chen, J, Chen, H, Li, S, Lin, X, Hu, R, Zhang, K, Liu, L. | Deposit date: | 2023-04-24 | Release date: | 2024-01-17 | Method: | ELECTRON MICROSCOPY (3.07 Å) | Cite: | Structural and mechanistic insights into ribosomal ITS2 RNA processing by nuclease-kinase machinery. Elife, 12, 2024
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8J60
| Structural and mechanistic insight into ribosomal ITS2 RNA processing by nuclease-kinase machinery | Descriptor: | LAS1 protein, Polynucleotide 5'-hydroxyl-kinase GRC3 | Authors: | Chen, J, Chen, H, Li, S, Lin, X, Hu, R, Zhang, K, Liu, L. | Deposit date: | 2023-04-24 | Release date: | 2024-01-17 | Method: | ELECTRON MICROSCOPY (3.39 Å) | Cite: | Structural and mechanistic insights into ribosomal ITS2 RNA processing by nuclease-kinase machinery. Elife, 12, 2024
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2I22
| Crystal structure of Escherichia coli phosphoheptose isomerase in complex with reaction substrate sedoheptulose 7-phosphate | Descriptor: | D-ALTRO-HEPT-2-ULOSE 7-PHOSPHATE, Phosphoheptose isomerase | Authors: | Blakely, K, Zhang, K, DeLeon, G, Wright, G, Junop, M. | Deposit date: | 2006-08-15 | Release date: | 2007-08-21 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure and Function of Sedoheptulose-7-phosphate Isomerase, a Critical Enzyme for Lipopolysaccharide Biosynthesis and a Target for Antibiotic Adjuvants J.Biol.Chem., 283, 2008
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2I2W
| Crystal Structure of Escherichia Coli Phosphoheptose Isomerase | Descriptor: | GLYCEROL, Phosphoheptose isomerase | Authors: | DeLeon, G, Blakely, K, Zhang, K, Wright, G, Junop, M. | Deposit date: | 2006-08-17 | Release date: | 2007-08-21 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structure and Function of Sedoheptulose-7-phosphate Isomerase, a Critical Enzyme for Lipopolysaccharide Biosynthesis and a Target for Antibiotic Adjuvants J.Biol.Chem., 283, 2008
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1SM5
| Crystal Structure of a DNA Decamer Containing a Thymine-dimer | Descriptor: | 5'-D(*CP*GP*AP*AP*TP*TP*AP*AP*GP*C)-3', 5'-D(*GP*CP*(BRU)P*TP*AP*AP*TP*(BRU)P*CP*G)-3' | Authors: | Park, H, Zhang, K, Ren, Y, Nadji, S, Sinha, N, Taylor, J.-S, Kang, C. | Deposit date: | 2004-03-08 | Release date: | 2004-05-25 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structure of a DNA Decamer Containing a Thymine-dimer Proc.Natl.Acad.Sci.USA, 99, 2002
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1T4I
| Crystal Structure of a DNA Decamer Containing a Thymine-dimer | Descriptor: | 5'-D(*CP*GP*AP*AP*TP*TP*AP*AP*GP*C)-3', 5'-D(*GP*CP*TP*TP*AP*AP*TP*TP*CP*G)-3' | Authors: | Park, H, Zhang, K, Ren, Y, Nadji, S, Sinha, N, Taylor, J.S, Kang, C. | Deposit date: | 2004-04-29 | Release date: | 2004-05-25 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal Structure of a DNA Decamer Containing a cis-syn Thymine-dimer Proc.Natl.Acad.Sci.USA, 99, 2002
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5HSI
| Crystal structure of tyrosine decarboxylase at 1.73 Angstroms resolution | Descriptor: | MAGNESIUM ION, Putative decarboxylase | Authors: | Ni, Y, Zhou, J, Zhu, H, Zhang, K. | Deposit date: | 2016-01-25 | Release date: | 2016-09-21 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.732 Å) | Cite: | Crystal structure of tyrosine decarboxylase and identification of key residues involved in conformational swing and substrate binding Sci Rep, 6, 2016
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5HSJ
| Structure of tyrosine decarboxylase complex with PLP at 1.9 Angstroms resolution | Descriptor: | PYRIDOXAL-5'-PHOSPHATE, Putative decarboxylase | Authors: | Ni, Y, Zhou, J, Zhu, H, Zhang, K. | Deposit date: | 2016-01-25 | Release date: | 2016-09-14 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of tyrosine decarboxylase and identification of key residues involved in conformational swing and substrate binding Sci Rep, 6, 2016
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6K61
| Cryo-EM structure of the tetrameric photosystem I from a heterocyst-forming cyanobacterium Anabaena sp. PCC7120 | Descriptor: | 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, ... | Authors: | Zheng, L, Li, Y, Li, X, Zhong, Q, Li, N, Zhang, K, Zhang, Y, Chu, H, Ma, C, Li, G, Zhao, J, Gao, N. | Deposit date: | 2019-05-31 | Release date: | 2019-10-09 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (2.37 Å) | Cite: | Structural and functional insights into the tetrameric photosystem I from heterocyst-forming cyanobacteria. Nat.Plants, 5, 2019
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3JUE
| Crystal Structure of ArfGAP and ANK repeat domain of ACAP1 | Descriptor: | ARFGAP with coiled-coil, ANK repeat and PH domain-containing protein 1, SULFATE ION, ... | Authors: | Pang, X, Zhang, K, Ma, J, Zhou, Q, Sun, F. | Deposit date: | 2009-09-15 | Release date: | 2010-09-22 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Mechanistic insights into regulated cargo binding by ACAP1 protein J.Biol.Chem., 287, 2012
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7KEK
| Structure of the free outer-arm dynein in pre-parallel state | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Dynein alpha heavy chain, ... | Authors: | Rao, Q, Zhang, K. | Deposit date: | 2020-10-11 | Release date: | 2021-09-29 | Last modified: | 2021-10-20 | Method: | ELECTRON MICROSCOPY (8 Å) | Cite: | Structures of outer-arm dynein array on microtubule doublet reveal a motor coordination mechanism. Nat.Struct.Mol.Biol., 28, 2021
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7K5B
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