7YPH

Open-spiral pentamer of the substrate-free Lon protease with a Y224S mutation

Summary for 7YPH

Entry DOI	10.2210/pdb7yph/pdb
EMDB information	34000
Descriptor	Lon protease, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER (2 entities in total)
Functional Keywords	lon protease, hydrolysis, aaa proteins, hydrolase
Biological source	Meiothermus taiwanensis
Total number of polymer chains	5
Total formula weight	443438.95
Authors	Li, S.,Hsieh, K.Y.,Kuo, C.I.,Lee, S.H.,Ho, M.R.,Wang, C.H.,Zhang, K.,Chang, C.I. (deposition date: 2022-08-03, release date: 2023-10-25, Last modification date: 2023-11-29)
Primary citation	Li, S.,Hsieh, K.Y.,Kuo, C.I.,Lin, T.C.,Lee, S.H.,Chen, Y.R.,Wang, C.H.,Ho, M.R.,Ting, S.Y.,Zhang, K.,Chang, C.I. A 5+1 assemble-to-activate mechanism of the Lon proteolytic machine. Nat Commun, 14:7340-7340, 2023 Cited by PubMed: 37957149 DOI: 10.1038/s41467-023-43035-2 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.68 Å)

Structure validation