2MLB
| NMR solution structure of a computational designed protein based on template of human erythrocytic ubiquitin | Descriptor: | redesigned ubiquitin | Authors: | Xiong, P, Wang, M, Zhang, J, Chen, Q, Liu, H. | Deposit date: | 2014-02-21 | Release date: | 2014-10-29 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Protein design with a comprehensive statistical energy function and boosted by experimental selection for foldability Nat Commun, 5, 2014
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2MN4
| NMR solution structure of a computational designed protein based on structure template 1cy5 | Descriptor: | Computational designed protein based on structure template 1cy5 | Authors: | Xiong, P, Wang, M, Zhang, J, Chen, Q, Liu, H. | Deposit date: | 2014-03-28 | Release date: | 2014-10-29 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Protein design with a comprehensive statistical energy function and boosted by experimental selection for foldability Nat Commun, 5, 2014
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5V93
| Cryo-EM structure of the 70S ribosome from Mycobacterium tuberculosis bound with Capreomycin | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Yang, K, Chang, J.-Y, Cui, Z, Li, X, Meng, R, Duan, L, Thongchol, J, Jakana, J, Huwe, C, Sacchettini, J, Zhang, J. | Deposit date: | 2017-03-22 | Release date: | 2017-09-20 | Last modified: | 2020-08-12 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Structural insights into species-specific features of the ribosome from the human pathogen Mycobacterium tuberculosis. Nucleic Acids Res., 45, 2017
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6C5W
| Crystal structure of the mitochondrial calcium uniporter | Descriptor: | CALCIUM ION, calcium uniporter, nanobody | Authors: | Fan, C, Fan, M, Fastman, N, Zhang, J, Feng, L. | Deposit date: | 2018-01-17 | Release date: | 2018-07-11 | Last modified: | 2019-04-24 | Method: | X-RAY DIFFRACTION (3.10010242 Å) | Cite: | X-ray and cryo-EM structures of the mitochondrial calcium uniporter. Nature, 559, 2018
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6DU8
| Human Polycsytin 2-l1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Polycystic kidney disease 2-like 1 protein | Authors: | Hulse, R.E, Clapham, D.E, Li, Z, Huang, R.K, Zhang, J. | Deposit date: | 2018-06-20 | Release date: | 2018-07-25 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3.11 Å) | Cite: | Cryo-EM structure of the polycystin 2-l1 ion channel. Elife, 7, 2018
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6K7V
| Structure of NLRP1 CARD filament | Descriptor: | NACHT, LRR and PYD domains-containing protein 1 | Authors: | Gong, Q, Xu, C, Zhang, J, Wu, B. | Deposit date: | 2019-06-09 | Release date: | 2020-09-16 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structural basis for distinct inflammasome complex assembly by human NLRP1 and CARD8. Nat Commun, 12, 2021
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6K9F
| Structure of unknow protein 4 | Descriptor: | Caspase recruitment domain-containing protein 8 | Authors: | Gong, Q, Xu, C, Zhang, J, Boo, Z.Z, Wu, B. | Deposit date: | 2019-06-15 | Release date: | 2020-09-16 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structural basis for distinct inflammasome complex assembly by human NLRP1 and CARD8. Nat Commun, 12, 2021
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2JXW
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5XBM
| Structure of SCARB2-JL2 complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Lysosome membrane protein 2, ... | Authors: | Zhang, X, Yang, P, Wang, N, Zhang, J, Li, J, Guo, H, Yin, X, Rao, Z, Wang, X, Zhang, L. | Deposit date: | 2017-03-20 | Release date: | 2018-06-27 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.501 Å) | Cite: | The binding of a monoclonal antibody to the apical region of SCARB2 blocks EV71 infection. Protein Cell, 8, 2017
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1XK9
| Pseudomanas exotoxin A in complex with the PJ34 inhibitor | Descriptor: | Exotoxin A, N~2~,N~2~-DIMETHYL-N~1~-(6-OXO-5,6-DIHYDROPHENANTHRIDIN-2-YL)GLYCINAMIDE | Authors: | Yates, S.P, Taylor, P.J, Joergensen, R, Ferrraris, D, Zhang, J, Andersen, G.R, Merrill, A.R. | Deposit date: | 2004-09-28 | Release date: | 2005-05-17 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure-function analysis of water-soluble inhibitors of the catalytic domain of exotoxin A from Pseudomonas aeruginosa BIOCHEM.J., 385, 2005
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8HVL
| Crystal structure of SARS-Cov-2 main protease M49I mutant in complex with PF07321332 | Descriptor: | (1R,2S,5S)-N-{(1E,2S)-1-imino-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-6,6-dimethyl-3-[3-methyl-N-(trifluoroacetyl)-L-valyl]-3-azabicyclo[3.1.0]hexane-2-carboxamide, 3C-like proteinase nsp5 | Authors: | Zou, X.F, Zhang, J, Li, J. | Deposit date: | 2022-12-27 | Release date: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Crystal structure of SARS-Cov-2 main protease
M49I mutant in complex with PF07321332 To Be Published
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8HVN
| Crystal structure of SARS-Cov-2 main protease P132H mutant in complex with PF07321332 | Descriptor: | (1R,2S,5S)-N-{(1E,2S)-1-imino-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-6,6-dimethyl-3-[3-methyl-N-(trifluoroacetyl)-L-valyl]-3-azabicyclo[3.1.0]hexane-2-carboxamide, 3C-like proteinase nsp5 | Authors: | Li, W.W, Zhang, J, Li, J. | Deposit date: | 2022-12-27 | Release date: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of SARS-Cov-2 main protease
P132H mutant in complex with PF07321332 To Be Published
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8HVK
| Crystal structure of SARS-Cov-2 main protease G15S mutant in complex with PF07321332 | Descriptor: | (1R,2S,5S)-N-{(1E,2S)-1-imino-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-6,6-dimethyl-3-[3-methyl-N-(trifluoroacetyl)-L-valyl]-3-azabicyclo[3.1.0]hexane-2-carboxamide, 3C-like proteinase nsp5 | Authors: | Zeng, P, Zhang, J, Li, J. | Deposit date: | 2022-12-27 | Release date: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.63 Å) | Cite: | Crystal structure of SARS-Cov-2 main protease
G15S mutant in complex with PF07321332 To Be Published
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8HVO
| Crystal structure of SARS-Cov-2 main protease V186F mutant in complex with PF07321332 | Descriptor: | (1R,2S,5S)-N-{(1E,2S)-1-imino-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-6,6-dimethyl-3-[3-methyl-N-(trifluoroacetyl)-L-valyl]-3-azabicyclo[3.1.0]hexane-2-carboxamide, 3C-like proteinase nsp5 | Authors: | Zou, X.F, Zhang, J, Li, J. | Deposit date: | 2022-12-27 | Release date: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Crystal structure of SARS-Cov-2 main protease
V186F mutant in complex with PF07321332 To Be Published
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2KXJ
| Solution structure of UBX domain of human UBXD2 protein | Descriptor: | UBX domain-containing protein 4 | Authors: | Wu, Q, Huang, H, Zhang, J, Hu, Q, Wu, J, Shi, Y. | Deposit date: | 2010-05-06 | Release date: | 2011-05-18 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Solution strcture of UBX domain of human UBXD2 protein To be Published
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2KU3
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8HUR
| Crystal structure of SARS-Cov-2 main protease in complex with S217622 | Descriptor: | 3C-like proteinase nsp5, 6-[(6-chloranyl-2-methyl-indazol-5-yl)amino]-3-[(1-methyl-1,2,4-triazol-3-yl)methyl]-1-[[2,4,5-tris(fluoranyl)phenyl]methyl]-1,3,5-triazine-2,4-dione | Authors: | Zhou, X.L, Zhang, J, Li, J. | Deposit date: | 2022-12-24 | Release date: | 2023-06-21 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.64 Å) | Cite: | Structural basis for the inhibition of coronaviral main proteases by ensitrelvir. Structure, 31, 2023
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8HUU
| Crystal structure of HCoV-NL63 main protease with S217622 | Descriptor: | 3C-like proteinase, 6-[(6-chloranyl-2-methyl-indazol-5-yl)amino]-3-[(1-methyl-1,2,4-triazol-3-yl)methyl]-1-[[2,4,5-tris(fluoranyl)phenyl]methyl]-1,3,5-triazine-2,4-dione | Authors: | Zeng, X.Y, Zhang, J, Li, J. | Deposit date: | 2022-12-24 | Release date: | 2023-06-21 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.71 Å) | Cite: | Structural basis for the inhibition of coronaviral main proteases by ensitrelvir. Structure, 31, 2023
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8HUV
| Crystal structure of SARS-Cov-2 main protease G15S mutant in complex with S217622 | Descriptor: | 3C-like proteinase nsp5, 6-[(6-chloranyl-2-methyl-indazol-5-yl)amino]-3-[(1-methyl-1,2,4-triazol-3-yl)methyl]-1-[[2,4,5-tris(fluoranyl)phenyl]methyl]-1,3,5-triazine-2,4-dione | Authors: | Zeng, P, Zhang, J, Li, J. | Deposit date: | 2022-12-24 | Release date: | 2023-06-21 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | Structural basis for the inhibition of coronaviral main proteases by ensitrelvir. Structure, 31, 2023
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8HUS
| Crystal structure of SARS main protease in complex with S217622 | Descriptor: | 3C-like proteinase nsp5, 6-[(6-chloranyl-2-methyl-indazol-5-yl)amino]-3-[(1-methyl-1,2,4-triazol-3-yl)methyl]-1-[[2,4,5-tris(fluoranyl)phenyl]methyl]-1,3,5-triazine-2,4-dione | Authors: | Lin, C, Zhang, J, Li, J. | Deposit date: | 2022-12-24 | Release date: | 2023-06-21 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | Structural basis for the inhibition of coronaviral main proteases by ensitrelvir. Structure, 31, 2023
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8HUX
| Crystal structure of SARS-Cov-2 main protease P132H mutant in complex with S217622 | Descriptor: | 3C-like proteinase nsp5, 6-[(6-chloranyl-2-methyl-indazol-5-yl)amino]-3-[(1-methyl-1,2,4-triazol-3-yl)methyl]-1-[[2,4,5-tris(fluoranyl)phenyl]methyl]-1,3,5-triazine-2,4-dione | Authors: | Li, W.W, Zhang, J, Li, J. | Deposit date: | 2022-12-24 | Release date: | 2023-06-21 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.74 Å) | Cite: | Structural basis for the inhibition of coronaviral main proteases by ensitrelvir. Structure, 31, 2023
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8HUT
| Crystal structure of MERS main protease in complex with S217622 | Descriptor: | 6-[(6-chloranyl-2-methyl-indazol-5-yl)amino]-3-[(1-methyl-1,2,4-triazol-3-yl)methyl]-1-[[2,4,5-tris(fluoranyl)phenyl]methyl]-1,3,5-triazine-2,4-dione, ORF1a | Authors: | Lin, C, Zhang, J, Li, J. | Deposit date: | 2022-12-24 | Release date: | 2023-06-21 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | Structural basis for the inhibition of coronaviral main proteases by ensitrelvir. Structure, 31, 2023
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2L43
| Structural basis for histone code recognition by BRPF2-PHD1 finger | Descriptor: | Histone H3.3,LINKER,Bromodomain-containing protein 1, ZINC ION | Authors: | Qin, S, Zhang, J, Wu, J, Shi, Y. | Deposit date: | 2010-10-01 | Release date: | 2011-08-31 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Recognition of unmodified histone H3 by the first PHD finger of Bromodomain-PHD finger protein 2 provides insights into the regulation of histone acetyltransferases MOZ and MORF To be Published
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1C39
| STRUCTURE OF CATION-DEPENDENT MANNOSE 6-PHOSPHATE RECEPTOR BOUND TO PENTAMANNOSYL PHOSPHATE | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 6-O-phosphono-alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose, CATION-DEPENDENT MANNOSE-6-PHOSPHATE RECEPTOR, ... | Authors: | Olson, L.J, Zhang, J, Lee, Y.C, Dahms, N.M, Kim, J.J.-P. | Deposit date: | 1999-07-25 | Release date: | 2000-01-14 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structural basis for recognition of phosphorylated high mannose oligosaccharides by the cation-dependent mannose 6-phosphate receptor. J.Biol.Chem., 274, 1999
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8HQH
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