2WV5
 
 | | Crystal structure of foot-and-mouth disease virus 3C protease in complex with a decameric peptide corresponding to the VP1-2A cleavage junction with a GLN to Glu substitution at P1 | | Descriptor: | FOOT AND MOUTH DISEASE VIRUS (SEROTYPE A) VARIANT VP1 CAPSID PROTEIN, PICORNAIN 3C | | Authors: | Zunszain, P.A, Knox, S.R, Sweeney, T.R, Yang, J, Roque-Rosell, N, Belsham, G.J, Leatherbarrow, R.J, Curry, S. | | Deposit date: | 2009-10-13 | | Release date: | 2009-10-27 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Insights Into Cleavage Specificity from the Crystal Structure of Foot-and-Mouth Disease Virus 3C Protease Complexed with a Peptide Substrate.
J.Mol.Biol., 395, 2010
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7CLT
 | | Crystal structure of the EFhd1/Swiprosin-2, a mitochondrial actin-binding protein | | Descriptor: | CALCIUM ION, EF-hand domain-containing protein D1, GLYCEROL, ... | | Authors: | Mun, S.A, Park, J, Park, K.R, Lee, Y, Kang, J.Y, Park, T, Jin, M, Yang, J, Jun, C.D, Eom, S.H. | | Deposit date: | 2020-07-22 | | Release date: | 2021-01-06 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.07380986 Å) | | Cite: | Structural and Biochemical Characterization of EFhd1/Swiprosin-2, an Actin-Binding Protein in Mitochondria.
Front Cell Dev Biol, 8, 2020
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1SYK
 | | Crystal structure of E230Q mutant of cAMP-dependent protein kinase reveals unexpected apoenzyme conformation | | Descriptor: | cAMP-dependent protein kinase, alpha-catalytic subunit | | Authors: | Wu, J, Yang, J, Madhusudan, N, Xuong, N.H, Ten Eyck, L.F, Taylor, S.S. | | Deposit date: | 2004-04-01 | | Release date: | 2005-05-17 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Crystal structure of the E230Q mutant of cAMP-dependent
protein kinase reveals an unexpected apoenzyme conformation and an
extended N-terminal A helix.
Protein Sci., 14, 2005
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1VYU
 | | Beta3 subunit of Voltage-gated Ca2+-channel | | Descriptor: | CALCIUM CHANNEL BETA-3 SUBUNIT | | Authors: | Chen, Y.-H, Li, M.-H, Zhang, Y, He, L.-L, Yamada, Y, Fitzmaurice, A, Yang, S, Zhang, H, Liang, T, Yang, J. | | Deposit date: | 2004-05-07 | | Release date: | 2004-06-15 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural Basis of the Alpha(1)-Beta Subunit Interaction of Voltage-Gated Ca(2+) Channels
Nature, 429, 2004
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1VYT
 | | beta3 subunit complexed with aid | | Descriptor: | CALCIUM CHANNEL BETA-3 SUBUNIT, VOLTAGE-DEPENDENT L-TYPE CALCIUM CHANNEL ALPHA-1C SUBUNIT | | Authors: | Chen, Y.-H, Li, M.-H, Zhang, Y, He, L.-L, Yamada, Y, Fitzmaurice, A, Yang, S, Zhang, H, Tong, L, Yang, J. | | Deposit date: | 2004-05-07 | | Release date: | 2004-06-15 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structural Basis of the Alpha(1)-Beta Subunit Interaction of Voltage-Gated Ca(2+) Channels
Nature, 429, 2004
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1VYV
 | | beta4 subunit of Ca2+ channel | | Descriptor: | CALCIUM CHANNEL BETA-4SUBUNIT | | Authors: | Chen, Y.-H, Li, M.-H, Zhang, Y, He, L.-L, Yamada, Y, Fitzmaurice, A, Yang, S, Zhang, H, Liang, T, Yang, J. | | Deposit date: | 2004-05-07 | | Release date: | 2004-06-15 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structural Basis of the Alpha(1)-Beta Subunit Interaction of Voltage-Gated Ca(2+) Channels
Nature, 429, 2004
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8HNS
 | | Crystal structure of an anti-CRISPR protein AcrIIC4 in apo form | | Descriptor: | GLYCEROL, anti-CRISPR protein AcrIIC4 | | Authors: | Sun, W, Cheng, Z, Yang, J, Wang, Y. | | Deposit date: | 2022-12-08 | | Release date: | 2023-07-19 | | Last modified: | 2023-08-02 | | Method: | X-RAY DIFFRACTION (2.54 Å) | | Cite: | AcrIIC4 inhibits type II-C Cas9 by preventing R-loop formation.
Proc.Natl.Acad.Sci.USA, 120, 2023
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5LCW
 | | Cryo-EM structure of the Anaphase-promoting complex/Cyclosome, in complex with the Mitotic checkpoint complex (APC/C-MCC) at 4.2 angstrom resolution | | Descriptor: | Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ... | | Authors: | Alfieri, C, Chang, L, Zhang, Z, Yang, J, Maslen, S, Skehel, M, Barford, D. | | Deposit date: | 2016-06-22 | | Release date: | 2016-08-10 | | Last modified: | 2019-10-23 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | Molecular basis of APC/C regulation by the spindle assembly checkpoint.
Nature, 536, 2016
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6JCJ
 | | Structure of crolibulin in complex with tubulin | | Descriptor: | (4R)-2,7,8-triamino-4-(3-bromo-4,5-dimethoxyphenyl)-4H-1-benzopyran-3-carbonitrile, CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, ... | | Authors: | Zhang, Z, Yang, J. | | Deposit date: | 2019-01-29 | | Release date: | 2019-03-13 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Molecular mechanism of crolibulin in complex with tubulin provides a rationale for drug design.
Biochem. Biophys. Res. Commun., 511, 2019
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5MZ6
 | | Cryo-EM structure of a Separase-Securin complex from Caenorhabditis elegans at 3.8 A resolution | | Descriptor: | Interactor of FizzY protein, SEParase | | Authors: | Boland, A, Martin, T.G, Zhang, Z, Yang, J, Bai, X.C, Chang, L, Scheres, S.H.W, Barford, D. | | Deposit date: | 2017-01-31 | | Release date: | 2017-03-08 | | Last modified: | 2019-12-11 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Cryo-EM structure of a metazoan separase-securin complex at near-atomic resolution.
Nat. Struct. Mol. Biol., 24, 2017
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3MWH
 | | The 1.4 Ang crystal structure of the ArsD arsenic metallochaperone provides insights into its interactions with the ArsA ATPase | | Descriptor: | Arsenical resistance operon trans-acting repressor arsD, GLYCEROL | | Authors: | Ye, J, Ajees, A.A, Yang, J, Rosen, B.P. | | Deposit date: | 2010-05-05 | | Release date: | 2010-05-26 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | The 1.4 A crystal structure of the ArsD arsenic metallochaperone provides insights into its interaction with the ArsA ATPase.
Biochemistry, 49, 2010
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2WV4
 | | Crystal structure of foot-and-mouth disease virus 3C protease in complex with a decameric peptide corresponding to the VP1-2A cleavage junction | | Descriptor: | FOOT AND MOUTH DISEASE VIRUS (SEROTYPE A) VARIANT VP1 CAPSID PROTEIN, PICORNAIN 3C | | Authors: | Zunszain, P.A, Knox, S.R, Sweeney, T.R, Yang, J, Roque-Rosell, N, Belsham, G.J, Leatherbarrow, R.J, Curry, S. | | Deposit date: | 2009-10-13 | | Release date: | 2009-10-27 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Insights Into Cleavage Specificity from the Crystal Structure of Foot-and-Mouth Disease Virus 3C Protease Complexed with a Peptide Substrate.
J.Mol.Biol., 395, 2010
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6TGB
 | | CryoEM structure of the binary DOCK2-ELMO1 complex | | Descriptor: | Dedicator of cytokinesis protein 2, Engulfment and cell motility protein 1 | | Authors: | Chang, L, Yang, J, Chang, J.H, Zhang, Z, Boland, A, McLaughlin, S.H, Abu-Thuraia, A, Killoran, R.C, Smith, M.J, Cote, J.F, Barford, D. | | Deposit date: | 2019-11-15 | | Release date: | 2020-07-29 | | Method: | ELECTRON MICROSCOPY (5.5 Å) | | Cite: | Structure of the DOCK2-ELMO1 complex provides insights into regulation of the auto-inhibited state.
Nat Commun, 11, 2020
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6TKY
 | | Crystal structure of the DHR2 domain of DOCK10 in complex with CDC42 | | Descriptor: | Cell division control protein 42 homolog, Dedicator of cytokinesis protein 10, GLYCEROL | | Authors: | Barford, D, Fan, D, Cronin, N, Yang, J. | | Deposit date: | 2019-11-29 | | Release date: | 2020-01-22 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.55 Å) | | Cite: | Structural basis for CDC42 and RAC activation by the dual specificity GEF DOCK10
Biorxiv, 2022
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6TM1
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6TGC
 | | CryoEM structure of the ternary DOCK2-ELMO1-RAC1 complex. | | Descriptor: | Dedicator of cytokinesis protein 2, Engulfment and cell motility protein 1, Ras-related C3 botulinum toxin substrate 1 | | Authors: | Chang, L, Yang, J, Chang, J.H, Zhang, Z, Boland, A, McLaughlin, S.H, Abu-Thuraia, A, Killoran, R.C, Smith, M.J, Cote, J.F, Barford, D. | | Deposit date: | 2019-11-15 | | Release date: | 2020-07-29 | | Last modified: | 2023-07-26 | | Method: | ELECTRON MICROSCOPY (4.1 Å) | | Cite: | Structure of the DOCK2-ELMO1 complex provides insights into regulation of the auto-inhibited state.
Nat Commun, 11, 2020
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2YIN
 | | STRUCTURE OF THE COMPLEX BETWEEN Dock2 AND Rac1. | | Descriptor: | DEDICATOR OF CYTOKINESIS PROTEIN 2, RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 1 | | Authors: | Kulkarni, K.A, Yang, J, Zhang, Z, Barford, D. | | Deposit date: | 2011-05-16 | | Release date: | 2011-05-25 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Multiple Factors Confer Specific Cdc42 and Rac Protein Activation by Dedicator of Cytokinesis (Dock) Nucleotide Exchange Factors.
J.Biol.Chem., 286, 2011
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7N17
 | | Structure of TAX-4_R421W apo open state | | Descriptor: | 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Cyclic nucleotide-gated cation channel | | Authors: | Zheng, X, Li, H, Hu, Z, Su, D, Yang, J. | | Deposit date: | 2021-05-27 | | Release date: | 2022-03-16 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Structural and functional characterization of an achromatopsia-associated mutation in a phototransduction channel.
Commun Biol, 5, 2022
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7N16
 | | Structure of TAX-4_R421W apo closed state | | Descriptor: | 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Cyclic nucleotide-gated cation channel, SODIUM ION | | Authors: | Zheng, X, Li, H, Hu, Z, Su, D, Yang, J. | | Deposit date: | 2021-05-27 | | Release date: | 2022-03-16 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Structural and functional characterization of an achromatopsia-associated mutation in a phototransduction channel.
Commun Biol, 5, 2022
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7N15
 | | Structure of TAX-4_R421W w/cGMP open state | | Descriptor: | 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHATE, 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CYCLIC GUANOSINE MONOPHOSPHATE, ... | | Authors: | Zheng, X, Li, H, Hu, Z, Su, D, Yang, J. | | Deposit date: | 2021-05-27 | | Release date: | 2022-03-16 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Structural and functional characterization of an achromatopsia-associated mutation in a phototransduction channel.
Commun Biol, 5, 2022
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3HFH
 | | Crystal structure of tandem FF domains | | Descriptor: | Transcription elongation regulator 1 | | Authors: | Lu, M, Yang, J, Ren, Z, Subir, S, Bedford, M.T, Jacobson, R.H, McMurray, J.S, Chen, X. | | Deposit date: | 2009-05-11 | | Release date: | 2009-08-18 | | Last modified: | 2017-11-01 | | Method: | X-RAY DIFFRACTION (2.703 Å) | | Cite: | Crystal Structure of the Three Tandem FF Domains of the Transcription Elongation Regulator CA150.
J.Mol.Biol., 393, 2009
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3HRO
 | | Crystal structure of a C-terminal coiled coil domain of Transient receptor potential (TRP) channel subfamily P member 2 (TRPP2, polycystic kidney disease 2) | | Descriptor: | Transient receptor potential (TRP) channel subfamily P member 2 (TRPP2), also called Polycystin-2 or polycystic kidney disease 2(PKD2) | | Authors: | Yu, Y, Ulbrich, M.H, Li, M.-H, Buraei, Z, Chen, X.-Z, Ong, A.C.M, Tong, L, Isacoff, E.Y, Yang, J. | | Deposit date: | 2009-06-09 | | Release date: | 2009-07-28 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural and molecular basis of the assembly of the TRPP2/PKD1 complex.
Proc.Natl.Acad.Sci.USA, 106, 2009
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3HRN
 | | crystal structure of a C-terminal coiled coil domain of Transient receptor potential (TRP) channel subfamily P member 2 (TRPP2, polycystic kidney disease 2) | | Descriptor: | Transient receptor potential (TRP) channel subfamily P member 2 (TRPP2) | | Authors: | Yu, Y, Ulbrich, M.H, Li, M.-H, Buraei, Z, Chen, X.-Z, Ong, A.C.M, Tong, L, Isacoff, E.Y, Yang, J. | | Deposit date: | 2009-06-09 | | Release date: | 2009-07-28 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural and molecular basis of the assembly of the TRPP2/PKD1 complex.
Proc.Natl.Acad.Sci.USA, 106, 2009
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2LGX
 | | NMR structure for Kindle-2 N-terminus | | Descriptor: | Fermitin family homolog 2 | | Authors: | Perera, H.D, Ma, Y, Yang, J, Hirbawi, J, Plow, E.F, Qin, J. | | Deposit date: | 2011-08-03 | | Release date: | 2011-11-30 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Membrane Binding of the N-Terminal Ubiquitin-Like Domain of kindlin-2 Is Crucial for Its Regulation of Integrin Activation.
Structure, 19, 2011
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6IGB
 | | the structure of Pseudomonas aeruginosa Periplasmic gluconolactonase, PpgL | | Descriptor: | ACETATE ION, Periplasmic gluconolactonase, PpgL, ... | | Authors: | Song, Y.J, Shen, Y.L, Wang, K.L, Li, T, Zhu, Y.B, Li, C.C, He, L.H, Zhao, N.L, Zhao, C, Yang, J, Huang, Q, Mu, X.Y. | | Deposit date: | 2018-09-25 | | Release date: | 2018-11-21 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.651 Å) | | Cite: | Structural and Functional Insights into PpgL, a Metal-Independent beta-Propeller Gluconolactonase That Contributes toPseudomonas aeruginosaVirulence.
Infect.Immun., 87, 2019
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