5J3Y
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![BU of 5j3y by Molmil](/molmil-images/mine/5j3y) | Crystal structure of S. pombe Dcp2:Dcp1 mRNA decapping complex | Descriptor: | mRNA decapping complex subunit 2, mRNA-decapping enzyme subunit 1 | Authors: | Valkov, E, Muthukumar, S, Chang, C.T, Jonas, S, Weichenrieder, O, Izaurralde, E. | Deposit date: | 2016-03-31 | Release date: | 2016-05-18 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.288 Å) | Cite: | Structure of the Dcp2-Dcp1 mRNA-decapping complex in the activated conformation. Nat.Struct.Mol.Biol., 23, 2016
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5J3T
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![BU of 5j3t by Molmil](/molmil-images/mine/5j3t) | Crystal structure of S. pombe Dcp2:Dcp1:Edc1 mRNA decapping complex | Descriptor: | Edc1, FORMIC ACID, MAGNESIUM ION, ... | Authors: | Valkov, E, Muthukumar, S, Chang, C.T, Jonas, S, Weichenrieder, O, Izaurralde, E. | Deposit date: | 2016-03-31 | Release date: | 2016-05-18 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structure of the Dcp2-Dcp1 mRNA-decapping complex in the activated conformation. Nat.Struct.Mol.Biol., 23, 2016
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5J3Q
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![BU of 5j3q by Molmil](/molmil-images/mine/5j3q) | Crystal structure of S. pombe Dcp1:Edc1 mRNA decapping complex | Descriptor: | Edc1, mRNA-decapping enzyme subunit 1 | Authors: | Valkov, E, Muthukumar, S, Chang, C.T, Jonas, S, Weichenrieder, O, Izaurralde, E. | Deposit date: | 2016-03-31 | Release date: | 2016-05-18 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.87 Å) | Cite: | Structure of the Dcp2-Dcp1 mRNA-decapping complex in the activated conformation. Nat.Struct.Mol.Biol., 23, 2016
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2Y92
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![BU of 2y92 by Molmil](/molmil-images/mine/2y92) | Crystal structure of MAL adaptor protein | Descriptor: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, TOLL/INTERLEUKIN-1 RECEPTOR DOMAIN-CONTAINING ADAPTER PROTEIN, | Authors: | Valkov, E, Stamp, A, Martin, J.L, Kobe, B. | Deposit date: | 2011-02-11 | Release date: | 2011-09-14 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.01 Å) | Cite: | Crystal Structure of Toll-Like Receptor Adaptor Mal/Tirap Reveals the Molecular Basis for Signal Transduction and Disease Protection. Proc.Natl.Acad.Sci.USA, 108, 2011
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3DLR
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![BU of 3dlr by Molmil](/molmil-images/mine/3dlr) | |
5C5W
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![BU of 5c5w by Molmil](/molmil-images/mine/5c5w) | 1.25 A resolution structure of an RNA 20-mer | Descriptor: | RNA (5'-R(P*CP*CP*UP*GP*AP*GP*UP*UP*CP*AP*AP*UP*UP*CP*UP*AP*GP*CP*G)-3') | Authors: | Stewart, M, Valkov, E. | Deposit date: | 2015-06-22 | Release date: | 2015-10-14 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.25 Å) | Cite: | 1.25 angstrom resolution structure of an RNA 20-mer that binds to the TREX2 complex. Acta Crystallogr.,Sect.F, 71, 2015
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4WPX
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![BU of 4wpx by Molmil](/molmil-images/mine/4wpx) | Chaetomium theromophilum TREX2 CID domain complex | Descriptor: | Cell division control protein 31-like protein, Putative SAC3 family protein, Putative uncharacterized protein | Authors: | Valkov, E, Stewart, M. | Deposit date: | 2014-10-21 | Release date: | 2015-06-17 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (3.31 Å) | Cite: | Structural Characterization of the Chaetomium thermophilum TREX-2 Complex and its Interaction with the mRNA Nuclear Export Factor Mex67:Mtr2. Structure, 23, 2015
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6FNY
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![BU of 6fny by Molmil](/molmil-images/mine/6fny) | CRYSTAL STRUCTURE OF A CHOLINE SULFATASE FROM SINORHIZOBIUM MELLILOTI | Descriptor: | CALCIUM ION, Choline-sulfatase | Authors: | Valkov, E, Van Loo, B, Hollfelder, F, Hyvonen, M. | Deposit date: | 2018-02-05 | Release date: | 2018-02-28 | Last modified: | 2018-04-04 | Method: | X-RAY DIFFRACTION (2.79 Å) | Cite: | Structural and Mechanistic Analysis of the Choline Sulfatase from Sinorhizobium melliloti: A Class I Sulfatase Specific for an Alkyl Sulfate Ester. J. Mol. Biol., 430, 2018
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4UPK
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![BU of 4upk by Molmil](/molmil-images/mine/4upk) | |
4AF0
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![BU of 4af0 by Molmil](/molmil-images/mine/4af0) | Crystal structure of cryptococcal inosine monophosphate dehydrogenase | Descriptor: | INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE, INOSINIC ACID, MYCOPHENOLIC ACID, ... | Authors: | Valkov, E, Stamp, A, Morrow, C.A, Kobe, B, Fraser, J.A. | Deposit date: | 2012-01-15 | Release date: | 2012-10-24 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | De Novo GTP Biosynthesis is Critical for Virulence of the Fungal Pathogen Cryptococcus Neoformans Plos Pathog., 8, 2012
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8FY4
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![BU of 8fy4 by Molmil](/molmil-images/mine/8fy4) | Structure of NOT1:NOT10:NOT11 module of the chicken CCR4-NOT complex | Descriptor: | CCR4-NOT transcription complex subunit 1, CCR4-NOT transcription complex subunit 10, CCR4-NOT transcription complex subunit 11 | Authors: | Lea, S.M, Deme, J.C, Raisch, T, Levdansky, Y, Valkov, E. | Deposit date: | 2023-01-25 | Release date: | 2023-08-30 | Method: | ELECTRON MICROSCOPY (2.57 Å) | Cite: | Structure and assembly of the NOT10:11 module of the CCR4-NOT complex. Commun Biol, 6, 2023
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8FY3
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![BU of 8fy3 by Molmil](/molmil-images/mine/8fy3) | Structure of NOT1:NOT10:NOT11 module of the human CCR4-NOT complex | Descriptor: | CCR4-NOT transcription complex subunit 1, CCR4-NOT transcription complex subunit 10, CCR4-NOT transcription complex subunit 11 | Authors: | Lea, S.M, Deme, J.C, Raisch, T, Pekovic, F, Valkov, E. | Deposit date: | 2023-01-25 | Release date: | 2023-07-26 | Last modified: | 2023-08-02 | Method: | ELECTRON MICROSCOPY (2.88 Å) | Cite: | Structure and assembly of the NOT10:11 module of the CCR4-NOT complex. Commun Biol, 6, 2023
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5FU7
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![BU of 5fu7 by Molmil](/molmil-images/mine/5fu7) | drosophila nanos NBR peptide bound to the NOT module of the human CCR4-NOT complex | Descriptor: | CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1, CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 2, CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 3, ... | Authors: | Raisch, T, Bhandari, D, Sabath, K, Helms, S, Valkov, E, Weichenrieder, O, Izaurralde, E. | Deposit date: | 2016-01-21 | Release date: | 2016-03-23 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Distinct Modes of Recruitment of the Ccr4-not Complex by Drosophila and Vertebrate Nanos Embo J., 35, 2016
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5FU6
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![BU of 5fu6 by Molmil](/molmil-images/mine/5fu6) | NOT module of the human CCR4-NOT complex (Crystallization mutant) | Descriptor: | CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1, CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 2, CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 3 | Authors: | Raisch, T, Bhandari, D, Sabath, K, Helms, S, Valkov, E, Weichenrieder, O, Izaurralde, E. | Deposit date: | 2016-01-21 | Release date: | 2016-03-23 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Distinct Modes of Recruitment of the Ccr4-not Complex by Drosophila and Vertebrate Nanos Embo J., 35, 2016
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6S8R
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![BU of 6s8r by Molmil](/molmil-images/mine/6s8r) | D. melanogaster RNA helicase Me31B in complex with GIGYF | Descriptor: | ACETATE ION, ATP-dependent RNA helicase me31b, GIGYF family protein CG11148 | Authors: | Peter, D, Valkov, E. | Deposit date: | 2019-07-10 | Release date: | 2019-09-04 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.41 Å) | Cite: | Molecular basis for GIGYF-Me31B complex assembly in 4EHP-mediated translational repression. Genes Dev., 33, 2019
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6S8S
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![BU of 6s8s by Molmil](/molmil-images/mine/6s8s) | |
3OZI
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![BU of 3ozi by Molmil](/molmil-images/mine/3ozi) | Crystal structure of the TIR domain from the flax disease resistance protein L6 | Descriptor: | COBALT (II) ION, L6tr | Authors: | Ve, T, Bernoux, M, Williams, S, Valkov, E, Warren, C, Hatters, D, Ellis, J.G, Dodds, P.N, Kobe, B. | Deposit date: | 2010-09-25 | Release date: | 2011-04-27 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural and Functional Analysis of a Plant Resistance Protein TIR Domain Reveals Interfaces for Self-Association, Signaling, and Autoregulation. Cell Host Microbe, 9, 2011
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4WPM
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![BU of 4wpm by Molmil](/molmil-images/mine/4wpm) | |
4WP6
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![BU of 4wp6 by Molmil](/molmil-images/mine/4wp6) | Structure of the Mex67 LRR domain from Chaetomium thermophilum | Descriptor: | mRNA export protein | Authors: | Aibara, S, Valkov, E, Lamers, M, Stewart, M. | Deposit date: | 2014-10-17 | Release date: | 2015-07-15 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural characterization of the principal mRNA-export factor Mex67-Mtr2 from Chaetomium thermophilum. Acta Crystallogr.,Sect.F, 71, 2015
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4LJ0
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![BU of 4lj0 by Molmil](/molmil-images/mine/4lj0) | Nab2 Zn fingers complexed with polyadenosine | Descriptor: | ACETATE ION, MAGNESIUM ION, Nab2, ... | Authors: | Stewart, M, Kuhlmann, S.I, Valkov, E. | Deposit date: | 2013-07-04 | Release date: | 2013-10-09 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Structural basis for the molecular recognition of polyadenosine RNA by Nab2 Zn fingers. Nucleic Acids Res., 42, 2014
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4X2O
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![BU of 4x2o by Molmil](/molmil-images/mine/4x2o) | Sac3N peptide bound to Mex67:Mtr2 | Descriptor: | Putative SAC3 family protein, Putative mRNA export protein, Putative uncharacterized protein | Authors: | Aibara, S, Valkov, E, Stewart, M. | Deposit date: | 2014-11-26 | Release date: | 2015-06-17 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structural Characterization of the Chaetomium thermophilum TREX-2 Complex and its Interaction with the mRNA Nuclear Export Factor Mex67:Mtr2. Structure, 23, 2015
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4WP5
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![BU of 4wp5 by Molmil](/molmil-images/mine/4wp5) | |
4X2M
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![BU of 4x2m by Molmil](/molmil-images/mine/4x2m) | Structure of Mtr2 | Descriptor: | Mtr2 | Authors: | Aibara, S, Valkov, E, Stewart, M. | Deposit date: | 2014-11-26 | Release date: | 2015-07-15 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural characterization of the principal mRNA-export factor Mex67-Mtr2 from Chaetomium thermophilum. Acta Crystallogr.,Sect.F, 71, 2015
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4X2H
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![BU of 4x2h by Molmil](/molmil-images/mine/4x2h) | Sac3N peptide bound to Mex67:Mtr2 | Descriptor: | Putative mRNA export protein, Putative uncharacterized protein, SER-SER-VAL-PHE-GLY-ALA-PRO-ALA | Authors: | Aibara, S, Valkov, E, Stewart, M. | Deposit date: | 2014-11-26 | Release date: | 2015-06-17 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural Characterization of the Chaetomium thermophilum TREX-2 Complex and its Interaction with the mRNA Nuclear Export Factor Mex67:Mtr2. Structure, 23, 2015
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5NVN
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![BU of 5nvn by Molmil](/molmil-images/mine/5nvn) | Crystal structure of the human 4EHP-4E-BP1 complex | Descriptor: | Eukaryotic translation initiation factor 4E type 2, Eukaryotic translation initiation factor 4E-binding protein 1, FORMIC ACID | Authors: | Peter, D, Sandmeir, F, Valkov, E. | Deposit date: | 2017-05-04 | Release date: | 2017-07-26 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | GIGYF1/2 proteins use auxiliary sequences to selectively bind to 4EHP and repress target mRNA expression. Genes Dev., 31, 2017
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