6W7J
| Structure of Tdp1 catalytic domain in complex with inhibitor XZ635p | Descriptor: | 1,2-ETHANEDIOL, 4-{[2-(2-hydroxyphenyl)imidazo[1,2-a]pyridin-3-yl]amino}benzene-1,2-dicarboxylic acid, Tyrosyl-DNA phosphodiesterase 1 | Authors: | Lountos, G.T, Zhao, X.Z, Kiselev, E, Tropea, J.E, Needle, D, Pommier, Y, Burke, T.R, Waugh, D.S. | Deposit date: | 2020-03-19 | Release date: | 2021-03-24 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.489 Å) | Cite: | Tdp1 catalytic domain To Be Published
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8DVH
| Crystal structure of ATP-dependent Lon protease from Bacillus subtillis (BsLonBA) | Descriptor: | Lon protease 2, N-[(1R)-1-(DIHYDROXYBORYL)-3-METHYLBUTYL]-N-(PYRAZIN-2-YLCARBONYL)-L-PHENYLALANINAMIDE, SODIUM ION | Authors: | Sekula, B, Li, M, Gustchina, A, Wlodawer, A. | Deposit date: | 2022-07-29 | Release date: | 2022-11-09 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Unique Structural Fold of LonBA Protease from Bacillus subtilis, a Member of a Newly Identified Subfamily of Lon Proteases. Int J Mol Sci, 23, 2022
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2IF5
| Structure of the POZ domain of human LRF, a master regulator of oncogenesis | Descriptor: | PRASEODYMIUM ION, Zinc finger and BTB domain-containing protein 7A | Authors: | Schubot, F.D, Waugh, D.S, Tropea, J. | Deposit date: | 2006-09-20 | Release date: | 2006-11-21 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure of the POZ domain of human LRF, a master regulator of oncogenesis. Biochem.Biophys.Res.Commun., 351, 2006
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6PC1
| Crystal structure of Helicobacter pylori PPX/GppA (E143A) in complex with ppGpp | Descriptor: | (2S)-2-hydroxybutanedioic acid, 1,2-ETHANEDIOL, GUANOSINE-5',3'-TETRAPHOSPHATE, ... | Authors: | Song, H, Wang, C, Shaw, G.X, Ji, X. | Deposit date: | 2019-06-15 | Release date: | 2019-11-20 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.76 Å) | Cite: | Structure and activity of PPX/GppA homologs from Escherichia coli and Helicobacter pylori. Febs J., 287, 2020
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6PC0
| Crystal structure of Helicobacter pylori PPX/GppA | Descriptor: | (2S)-2-hydroxybutanedioic acid, 1,2-ETHANEDIOL, D-MALATE, ... | Authors: | Song, H, Wang, C, Shaw, G.X, Ji, X. | Deposit date: | 2019-06-15 | Release date: | 2019-11-20 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structure and activity of PPX/GppA homologs from Escherichia coli and Helicobacter pylori. Febs J., 287, 2020
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6PBZ
| Crystal structure of Escherichia coli GppA | Descriptor: | CHLORIDE ION, Guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase | Authors: | Song, H, Shaw, G.X, Wang, C, Ji, X. | Deposit date: | 2019-06-15 | Release date: | 2019-11-20 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.475 Å) | Cite: | Structure and activity of PPX/GppA homologs from Escherichia coli and Helicobacter pylori. Febs J., 287, 2020
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6PC3
| Crystal structure of Helicobacter pylori PPX/GppA in complex with GSP | Descriptor: | 1,2-ETHANEDIOL, 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, CHLORIDE ION, ... | Authors: | Song, H, Wang, C, Shaw, G.X, Ji, X. | Deposit date: | 2019-06-15 | Release date: | 2019-11-20 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure and activity of PPX/GppA homologs from Escherichia coli and Helicobacter pylori. Febs J., 287, 2020
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6PC2
| Crystal structure of Helicobacter pylori PPX/GppA in complex with GNP | Descriptor: | Guanosine pentaphosphate phosphohydrolase, MAGNESIUM ION, PHOSPHATE ION, ... | Authors: | Song, H, Wang, C, Shaw, G.X, Ji, X. | Deposit date: | 2019-06-15 | Release date: | 2019-11-20 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structure and activity of PPX/GppA homologs from Escherichia coli and Helicobacter pylori. Febs J., 287, 2020
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1RC5
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1RC7
| Crystal structure of RNase III Mutant E110K from Aquifex Aeolicus complexed with ds-RNA at 2.15 Angstrom Resolution | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5'-R(*GP*GP*CP*GP*CP*GP*CP*GP*CP*C)-3', Ribonuclease III | Authors: | Blaszczyk, J, Gan, J, Ji, X. | Deposit date: | 2003-11-03 | Release date: | 2004-03-30 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Noncatalytic Assembly of Ribonuclease III with Double-Stranded RNA. Structure, 12, 2004
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6XBC
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6XBB
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3IEU
| Crystal Structure of ERA in Complex with GDP | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GTP-binding protein era, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Tu, C, Ji, X. | Deposit date: | 2009-07-23 | Release date: | 2009-08-25 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure of ERA in complex with the 3' end of 16S rRNA: implications for ribosome biogenesis Proc.Natl.Acad.Sci.USA, 106, 2009
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3IEV
| Crystal Structure of ERA in Complex with MgGNP and the 3' End of 16S rRNA | Descriptor: | 5'-R(P*AP*UP*CP*AP*CP*CP*UP*CP*CP*UP*UP*A)-3', GTP-binding protein era, MAGNESIUM ION, ... | Authors: | Tu, C, Ji, X. | Deposit date: | 2009-07-23 | Release date: | 2009-08-25 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure of ERA in complex with the 3' end of 16S rRNA: implications for ribosome biogenesis Proc.Natl.Acad.Sci.USA, 106, 2009
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3IO2
| Crystal structure of the Taz2 domain of p300 | Descriptor: | Histone acetyltransferase p300, SULFATE ION, ZINC ION | Authors: | Miller, M, Dauter, Z, Wlodawer, A. | Deposit date: | 2009-08-13 | Release date: | 2009-11-24 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure of the Taz2 domain of p300: insights into ligand binding. Acta Crystallogr.,Sect.D, 65, 2009
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2K5S
| YmoA | Descriptor: | Modulating protein ymoA | Authors: | McFeeters, R.L, Byrd, R. | Deposit date: | 2008-06-30 | Release date: | 2008-12-09 | Last modified: | 2022-03-16 | Method: | SOLUTION NMR | Cite: | The high-precision solution structure of Yersinia modulating
protein YmoA provides insight into interaction with H-NS Biochemistry, 46, 2007
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2K8F
| Structural Basis for the Regulation of p53 Function by p300 | Descriptor: | Cellular tumor antigen p53, Histone acetyltransferase p300 | Authors: | Bai, Y, Feng, H, Jenkins, L.M, Durell, S.R, Wiodawer, A, Appella, E. | Deposit date: | 2008-09-08 | Release date: | 2009-03-03 | Last modified: | 2021-10-20 | Method: | SOLUTION NMR | Cite: | Structural Basis for p300 Taz2-p53 TAD1 Binding and Modulation by Phosphorylation. Structure, 17, 2009
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1I4S
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1JFZ
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1HUF
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7R97
| Crystal structure of postcleavge complex of Escherichia coli RNase III | Descriptor: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, ... | Authors: | Dharavath, S, Shaw, G.X, Ji, X. | Deposit date: | 2021-06-28 | Release date: | 2022-07-20 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.804 Å) | Cite: | Structural basis for Dicer-like function of an engineered RNase III variant and insights into the reaction trajectory of two-Mg 2+ -ion catalysis. Rna Biol., 19, 2022
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1N5B
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7KDR
| Crystal structure of Escherichia coli HPPK in complex with bisubstrate inhibitor HP-75 | Descriptor: | 1,2-ETHANEDIOL, 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, 5'-{[(2R,4R)-1-{2-[(2-amino-7,7-dimethyl-4-oxo-3,4,7,8-tetrahydropteridine-6-carbonyl)amino]ethyl}-2-carboxypiperidin-4-yl]sulfonyl}-5'-deoxyadenosine, ... | Authors: | Shaw, G.X, Shi, G, Ji, X. | Deposit date: | 2020-10-09 | Release date: | 2020-12-02 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.488 Å) | Cite: | Bisubstrate inhibitors of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase: Transition state analogs for high affinity binding. Bioorg.Med.Chem., 29, 2021
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7KDO
| Crystal structure of Escherichia coli HPPK in complex with bisubstrate inhibitor HP-73 | Descriptor: | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, 5'-S-[(2R,4R)-1-{2-[(2-amino-7,7-dimethyl-4-oxo-3,4,7,8-tetrahydropteridine-6-carbonyl)amino]ethyl}-2-carboxypiperidin-4-yl]-5'-thioadenosine | Authors: | Shaw, G.X, Shi, G, Ji, X. | Deposit date: | 2020-10-09 | Release date: | 2020-12-02 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Bisubstrate inhibitors of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase: Transition state analogs for high affinity binding. Bioorg.Med.Chem., 29, 2021
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1Z0V
| Crystal Structure of A. fulgidus Lon proteolytic domain | Descriptor: | Putative protease La homolog type | Authors: | Dauter, Z, Botos, I, LaRonde-LeBlanc, N, Wlodawer, A. | Deposit date: | 2005-03-02 | Release date: | 2005-08-02 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Pathological crystallography: case studies of several unusual macromolecular crystals. Acta Crystallogr.,Sect.D, 61, 2005
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