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7P60
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BU of 7p60 by Molmil
Structure of homomeric LRRC8A Volume-Regulated Anion Channel in complex with synthetic nanobody Sb4 at 1:0.5 ratio
Descriptor: Volume-regulated anion channel subunit LRRC8A, synthetic nanobody Sb4
Authors:Deneka, D, Rutz, S, Sawicka, M.
Deposit date:2021-07-15
Release date:2021-09-15
Last modified:2021-10-13
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Allosteric modulation of LRRC8 channels by targeting their cytoplasmic domains.
Nat Commun, 12, 2021
7P5V
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BU of 7p5v by Molmil
Structure of homomeric LRRC8A Volume-Regulated Anion Channel in complex with synthetic nanobody Sb1
Descriptor: Synthetic nanobody Sb1, Volume-regulated anion channel subunit LRRC8A
Authors:Deneka, D, Rutz, S, Sawicka, M.
Deposit date:2021-07-15
Release date:2021-09-15
Last modified:2021-10-13
Method:ELECTRON MICROSCOPY (3.06 Å)
Cite:Allosteric modulation of LRRC8 channels by targeting their cytoplasmic domains.
Nat Commun, 12, 2021
7P5Y
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BU of 7p5y by Molmil
Structure of homomeric LRRC8A Volume-Regulated Anion Channel in complex with synthetic nanobody Sb3
Descriptor: Volume-regulated anion channel subunit LRRC8A, synthetic nanobody Sb3
Authors:Deneka, D, Rutz, S, Sawicka, M.
Deposit date:2021-07-15
Release date:2021-09-15
Last modified:2021-10-13
Method:ELECTRON MICROSCOPY (3.29 Å)
Cite:Allosteric modulation of LRRC8 channels by targeting their cytoplasmic domains.
Nat Commun, 12, 2021
7P5W
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BU of 7p5w by Molmil
Structure of homomeric LRRC8A Volume-Regulated Anion Channel in complex with synthetic nanobody Sb2
Descriptor: Volume-regulated anion channel subunit LRRC8A, synthetic nanobody Sb2
Authors:Deneka, D, Rutz, S, Sawicka, M.
Deposit date:2021-07-15
Release date:2021-09-15
Last modified:2021-10-13
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Allosteric modulation of LRRC8 channels by targeting their cytoplasmic domains.
Nat Commun, 12, 2021
7P6K
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BU of 7p6k by Molmil
Structure of homomeric LRRC8A Volume-Regulated Anion Channel in complex with synthetic nanobody Sb5
Descriptor: Volume-regulated anion channel subunit LRRC8A, synthetic nanobody Sb5
Authors:Deneka, D, Rutz, S, Sawicka, M.
Deposit date:2021-07-16
Release date:2021-09-15
Last modified:2021-10-13
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Allosteric modulation of LRRC8 channels by targeting their cytoplasmic domains.
Nat Commun, 12, 2021
7ZK3
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BU of 7zk3 by Molmil
Structure of 1PBC- and calcium-bound mTMEM16A(ac) chloride channel at 2.85 A resolution
Descriptor: 1-Hydroxy-3-(trifluoromethyl)pyrido[1,2-a]benzimidazole-4-carbonitrile, Anoctamin-1, CALCIUM ION
Authors:Lam, A.K.M, Rutz, S, Dutzler, R.
Deposit date:2022-04-12
Release date:2022-05-25
Last modified:2022-06-01
Method:ELECTRON MICROSCOPY (2.85 Å)
Cite:Inhibition mechanism of the chloride channel TMEM16A by the pore blocker 1PBC.
Nat Commun, 13, 2022
8B40
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BU of 8b40 by Molmil
Structure of homomeric LRRC8C Volume-Regulated Anion Channel
Descriptor: Volume-regulated anion channel subunit LRRC8C
Authors:Sawicka, M, Dutzler, R.
Deposit date:2022-09-19
Release date:2022-12-14
Last modified:2023-02-01
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Structure of a volume-regulated heteromeric LRRC8A/C channel.
Nat.Struct.Mol.Biol., 30, 2023
8B41
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BU of 8b41 by Molmil
Structure of heteromeric LRRC8A/C (1:1 co-transfected) Volume-Regulated Anion Channel in complex with synthetic nanobody Sb1
Descriptor: Synthetic nanobody Sb1, Volume-regulated anion channel subunit LRRC8A, Volume-regulated anion channel subunit LRRC8C
Authors:Sawicka, M, Dutzler, R.
Deposit date:2022-09-19
Release date:2022-12-14
Last modified:2023-02-01
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structure of a volume-regulated heteromeric LRRC8A/C channel.
Nat.Struct.Mol.Biol., 30, 2023
8B42
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BU of 8b42 by Molmil
Structure of heteromeric LRRC8A/C Volume-Regulated Anion Channel.
Descriptor: Volume-regulated anion channel subunit LRRC8A, Volume-regulated anion channel subunit LRRC8C
Authors:Sawicka, M, Dutzler, R.
Deposit date:2022-09-19
Release date:2022-12-14
Last modified:2023-07-26
Method:ELECTRON MICROSCOPY (6.6 Å)
Cite:Structure of a volume-regulated heteromeric LRRC8A/C channel.
Nat.Struct.Mol.Biol., 30, 2023
8BEN
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BU of 8ben by Molmil
LRR domain Structure of the LRRC8C protein
Descriptor: Volume-regulated anion channel subunit LRRC8C
Authors:Sawicka, M, Dutzler, R.
Deposit date:2022-10-21
Release date:2022-12-14
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure of a volume-regulated heteromeric LRRC8A/C channel.
Nat.Struct.Mol.Biol., 30, 2023
8TLM
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BU of 8tlm by Molmil
Structure of a class A GPCR/Fab complex
Descriptor: C-C chemokine receptor type 8, Green fluorescent protein fusion, Fab heavy chain, ...
Authors:Sun, D, Johnson, M, Masureel, M.
Deposit date:2023-07-27
Release date:2023-12-20
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural basis of antibody inhibition and chemokine activation of the human CC chemokine receptor 8.
Nat Commun, 14, 2023
8U1U
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BU of 8u1u by Molmil
Structure of a class A GPCR/agonist complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, C-C motif chemokine 1,C-C chemokine receptor type 8,EGFP fusion protein, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Sun, D, Johnson, M, Masureel, M.
Deposit date:2023-09-02
Release date:2023-12-20
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural basis of antibody inhibition and chemokine activation of the human CC chemokine receptor 8.
Nat Commun, 14, 2023

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