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7BLR
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BU of 7blr by Molmil
Vps35/Vps29 arch of fungal membrane-assembled retromer:Vps5 (SNX-BAR) complex.
Descriptor: Vacuolar protein sorting-associated protein 29, Vacuolar protein sorting-associated protein 35
Authors:Leneva, N, Kovtun, O, Morado, D.R, Briggs, J.A.G, Owen, D.J.
Deposit date:2021-01-18
Release date:2021-02-10
Last modified:2021-04-07
Method:ELECTRON MICROSCOPY (9.3 Å)
Cite:Architecture and mechanism of metazoan retromer:SNX3 tubular coat assembly.
Sci Adv, 7, 2021
7BLP
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BU of 7blp by Molmil
Vps35/Vps29 arch of fungal membrane-assembled retromer:Grd19 complex
Descriptor: Vacuolar protein sorting-associated protein 29, Vacuolar protein sorting-associated protein 35
Authors:Leneva, N, Kovtun, O, Morado, D.R, Briggs, J.A.G, Owen, D.J.
Deposit date:2021-01-18
Release date:2021-02-10
Last modified:2021-04-07
Method:ELECTRON MICROSCOPY (9.5 Å)
Cite:Architecture and mechanism of metazoan retromer:SNX3 tubular coat assembly.
Sci Adv, 7, 2021
7BLO
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BU of 7blo by Molmil
VPS26 dimer region of metazoan membrane-assembled retromer:SNX3 complex modelled with human proteins
Descriptor: 2-(BUTANOYLOXY)-1-{[(HYDROXY{[2,3,4,6-TETRAHYDROXY-5-(PHOSPHONOOXY)CYCLOHEXYL]OXY}PHOSPHORYL)OXY]METHYL}ETHYL BUTANOATE, C-term (residues 493-54) of Wls (fitted sequence corresponds to hDMT1-II), Sorting nexin-3, ...
Authors:Leneva, N, Kovtun, O, Morado, D.R, Briggs, J.A.G, Owen, D.J.
Deposit date:2021-01-18
Release date:2021-03-03
Last modified:2021-04-07
Method:ELECTRON MICROSCOPY (9.5 Å)
Cite:Architecture and mechanism of metazoan retromer:SNX3 tubular coat assembly.
Sci Adv, 7, 2021
7BLQ
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BU of 7blq by Molmil
Vps26 dimer region of the fungal membrane-assembled retromer:Grd19 complex.
Descriptor: 2-(BUTANOYLOXY)-1-{[(HYDROXY{[2,3,4,6-TETRAHYDROXY-5-(PHOSPHONOOXY)CYCLOHEXYL]OXY}PHOSPHORYL)OXY]METHYL}ETHYL BUTANOATE, Sorting nexin-3, The C-terminal portion of Kex2 cargo, ...
Authors:Leneva, N, Kovtun, O, Morado, D.R, Briggs, J.A.G, Owen, D.J.
Deposit date:2021-01-18
Release date:2021-03-03
Last modified:2021-04-07
Method:ELECTRON MICROSCOPY (9.2 Å)
Cite:Architecture and mechanism of metazoan retromer:SNX3 tubular coat assembly.
Sci Adv, 7, 2021
6QH5
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BU of 6qh5 by Molmil
AP2 clathrin adaptor mu2T156-phosphorylated core in closed conformation
Descriptor: AP-2 complex subunit alpha, AP-2 complex subunit beta, AP-2 complex subunit mu, ...
Authors:Wrobel, A.G, Owen, D.J, McCoy, A.J, Evans, P.R.
Deposit date:2019-01-15
Release date:2019-09-04
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.56 Å)
Cite:Temporal Ordering in Endocytic Clathrin-Coated Vesicle Formation via AP2 Phosphorylation.
Dev.Cell, 50, 2019
7Z5C
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BU of 7z5c by Molmil
Chimera of AP2 with FCHO2 linker domain as a fusion on Cmu2 subunit
Descriptor: AP-2 complex subunit alpha-2, AP-2 complex subunit beta, AP-2 complex subunit mu, ...
Authors:Kane Dickson, V, Qu, K, Owen, D.J, Briggs, J.A, Zaccai, N.R.
Deposit date:2022-03-09
Release date:2022-05-11
Method:ELECTRON MICROSCOPY (4.16 Å)
Cite:FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P 2 -dependent switch.
Sci Adv, 8, 2022
1NAF
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BU of 1naf by Molmil
Crystal structure of the human GGA1 GAT domain
Descriptor: ADP-ribosylation factor binding protein GGA1
Authors:Collins, B.M, Watson, P.J, Owen, D.J.
Deposit date:2002-11-27
Release date:2003-03-25
Last modified:2018-02-14
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The Structure of the GGA1-GAT Domain Reveals the Molecular Basis for ARF Binding and Membrane Association of GGAs
Dev.Cell, 4, 2003
1NA8
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BU of 1na8 by Molmil
Crystal structure of ADP-ribosylation factor binding protein GGA1
Descriptor: ADP-ribosylation factor binding protein GGA1
Authors:Lui, W.W, Collins, B.M, Hirst, J, Motley, A, Millar, C, Schu, P, Owen, D.J, Robinson, M.S.
Deposit date:2002-11-27
Release date:2003-07-29
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Binding partners for the COOH-terminal appendage domains of the GGAs and gamma-adaptin
Mol.Cell.Biol., 14, 2003
1OM9
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BU of 1om9 by Molmil
Structure of the GGA1-appendage in complex with the p56 binding peptide
Descriptor: 15-mer peptide fragment of p56, ADP-ribosylation factor binding protein GGA1
Authors:Collins, B.M, Praefcke, G.J.K, Robinson, M.S, Owen, D.J.
Deposit date:2003-02-25
Release date:2003-07-29
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for binding of accessory proteins by the appendage domain of GGAs
Nat.Struct.Biol., 10, 2003
1R4X
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BU of 1r4x by Molmil
Crystal Structure Analys of the Gamma-COPI Appendage domain
Descriptor: Coatomer gamma subunit, MAGNESIUM ION
Authors:Watson, P.J, Frigerio, G, Collins, B.M, Duden, R, Owen, D.J.
Deposit date:2003-10-09
Release date:2003-10-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Gamma-COP appendage domain - structure and function
Traffic, 5, 2004
5JP2
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BU of 5jp2 by Molmil
Fcho1 Mu homology domain (Danio Rerio) with bound Eps15 peptide
Descriptor: Epidermal growth factor receptor substrate 15, F-BAR domain only protein 1, ZINC ION
Authors:McCoy, A.J, Wrobel, A, Owen, D.J.
Deposit date:2016-05-03
Release date:2016-06-08
Last modified:2016-06-15
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Transient Fcho1/2Eps15/RAP-2 Nanoclusters Prime the AP-2 Clathrin Adaptor for Cargo Binding.
Dev.Cell, 37, 2016
1UTC
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BU of 1utc by Molmil
Clathrin terminal domain complexed with TLPWDLWTT
Descriptor: AMPHIPHYSIN, CLATHRIN HEAVY CHAIN
Authors:Miele, A.E, Evans, P.R, Owen, D.J.
Deposit date:2003-12-08
Release date:2004-02-25
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Two distinct interaction motifs in amphiphysin bind two independent sites on the clathrin terminal domain beta-propeller.
Nat. Struct. Mol. Biol., 11, 2004
6H7W
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BU of 6h7w by Molmil
Model of retromer-Vps5 complex assembled on membrane.
Descriptor: Putative vacuolar protein sorting-associated protein, Vacuolar protein sorting-associated protein 26-like protein, Vacuolar protein sorting-associated protein 29, ...
Authors:Kovtun, O, Leneva, N, Ariotti, N, Rohan, T.S, Owen, D.J, Briggs, J.A.G, Collins, B.M.
Deposit date:2018-07-31
Release date:2018-09-26
Last modified:2018-10-10
Method:ELECTRON MICROSCOPY (11.4 Å)
Cite:Structure of the membrane-assembled retromer coat determined by cryo-electron tomography.
Nature, 561, 2018
7OIT
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BU of 7oit by Molmil
Crystal structure of AP2 Mu2 in complex with FCHO2 WxxPhi motif (P3221 crystal form)
Descriptor: AP-2 complex subunit mu, F-BAR domain only protein 2, GLYCEROL
Authors:Zaccai, N.R, Kelly, B.T, Evans, P.R, Owen, D.J.
Deposit date:2021-05-12
Release date:2022-06-01
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P 2 -dependent switch.
Sci Adv, 8, 2022
7OHO
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BU of 7oho by Molmil
Crystal structure of AP2 FCHO2 chimera
Descriptor: AP-2 complex subunit alpha-2, AP-2 complex subunit beta,F-BAR domain only protein 2, AP-2 complex subunit mu, ...
Authors:Zaccai, N.R, Kelly, B.T, Evans, P.R, Owen, D.J.
Deposit date:2021-05-11
Release date:2022-06-01
Method:X-RAY DIFFRACTION (2.88 Å)
Cite:FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P 2 -dependent switch.
Sci Adv, 8, 2022
7OG1
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BU of 7og1 by Molmil
AP2 clathrin adaptor core in complex with cargo peptide and FCHO2
Descriptor: AP-2 complex subunit alpha-2, AP-2 complex subunit beta, AP-2 complex subunit mu, ...
Authors:Zaccai, N.R, Kelly, B.T, Evans, P.R, Owen, D.J.
Deposit date:2021-05-05
Release date:2022-06-01
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P 2 -dependent switch.
Sci Adv, 8, 2022
7OIQ
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BU of 7oiq by Molmil
Crystal structure of AP2 Mu2 in complex with FCHO2 WxxPhi motif (C2 crystal form)
Descriptor: AP-2 complex subunit mu, F-BAR domain only protein 2
Authors:Zaccai, N.R, Kelly, B.T, Evans, P.R, Owen, D.J.
Deposit date:2021-05-12
Release date:2022-06-01
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P 2 -dependent switch.
Sci Adv, 8, 2022
7OHI
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BU of 7ohi by Molmil
FCHO1-peptide-AP2 alpha ear complex
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, AP-2 complex subunit alpha-2, F-BAR domain only protein 1, ...
Authors:Zaccai, N.R, Kelly, B.T, Evans, P.R, Owen, D.J.
Deposit date:2021-05-11
Release date:2022-06-01
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.41 Å)
Cite:FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P 2 -dependent switch.
Sci Adv, 8, 2022
7OI5
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BU of 7oi5 by Molmil
Crystal structure of AP2 Mu2 - FCHO2 chimera (GST cleaved)
Descriptor: AP-2 complex subunit mu,F-BAR domain only protein 2, GLYCEROL
Authors:Zaccai, N.R, Kelly, B.T, Evans, P.R, Owen, D.J.
Deposit date:2021-05-11
Release date:2022-06-01
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P 2 -dependent switch.
Sci Adv, 8, 2022
7OFP
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BU of 7ofp by Molmil
Apo Structure of Mu2 Adaptin Subunit (Ap50) Of AP2 Clathrin Adaptor
Descriptor: AP-2 complex subunit mu, CITRIC ACID, GLYCEROL
Authors:Zaccai, N.R, Kelly, B.T, Evans, P.R, Owen, D.J.
Deposit date:2021-05-05
Release date:2022-06-01
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P 2 -dependent switch.
Sci Adv, 8, 2022
7OHZ
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BU of 7ohz by Molmil
Crystal structure of AP2 Mu2 - FCHO2 chimera (His6-tagged)
Descriptor: AP-2 complex subunit mu,F-BAR domain only protein 2
Authors:Zaccai, N.R, Kelly, B.T, Evans, P.R, Owen, D.J.
Deposit date:2021-05-11
Release date:2022-06-01
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P 2 -dependent switch.
Sci Adv, 8, 2022
6QH6
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BU of 6qh6 by Molmil
AP2 clathrin adaptor core with two cargo peptides in open+ conformation
Descriptor: AP-2 complex subunit alpha, AP-2 complex subunit beta, AP-2 complex subunit mu, ...
Authors:Wrobel, A.G, Owen, D.J, McCoy, A.J, Evans, P.R.
Deposit date:2019-01-15
Release date:2019-09-04
Last modified:2022-12-07
Method:X-RAY DIFFRACTION (5 Å)
Cite:Temporal Ordering in Endocytic Clathrin-Coated Vesicle Formation via AP2 Phosphorylation.
Dev.Cell, 50, 2019
6QH7
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BU of 6qh7 by Molmil
AP2 clathrin adaptor mu2T156-phosphorylated core with two cargo peptides in open+ conformation
Descriptor: ADAPTOR-RELATED PROTEIN COMPLEX 2, MU 2 SUBUNIT, C-TERMINAL DOMAIN, ...
Authors:Wrobel, A.G, Owen, D.J, McCoy, A.J, Evans, P.R.
Deposit date:2019-01-15
Release date:2019-09-04
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Temporal Ordering in Endocytic Clathrin-Coated Vesicle Formation via AP2 Phosphorylation.
Dev.Cell, 50, 2019
1GYW
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BU of 1gyw by Molmil
Gamma-adaptin appendage domain from clathrin adaptor AP1 A753D mutant
Descriptor: ADAPTER-RELATED PROTEIN COMPLEX 1 GAMMA 1 SUBUNIT, CHLORIDE ION
Authors:Evans, P.R, Miele, A.E, Owen, D.J, McMahon, H.M, Kent, H.M.
Deposit date:2002-04-30
Release date:2002-08-22
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Gamma-adaptin appendage domain: structure and binding site for Eps15 and gamma-synergin.
Structure, 10, 2002
1GYV
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BU of 1gyv by Molmil
Gamma-adaptin appendage domain from clathrin adaptor AP1, L762E mutant
Descriptor: ADAPTER-RELATED PROTEIN COMPLEX 1 GAMMA 1 SUBUNIT
Authors:Evans, P.R, Owen, D.J, McMahon, H.M, Kent, H.M.
Deposit date:2002-04-30
Release date:2002-08-22
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:Gamma-adaptin appendage domain: structure and binding site for Eps15 and gamma-synergin.
Structure, 10, 2002

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