7OIT

Crystal structure of AP2 Mu2 in complex with FCHO2 WxxPhi motif (P3221 crystal form)

This is a non-PDB format compatible entry.

Summary for 7OIT

• Entry DOI: 10.2210/pdb7oit/pdb
• Descriptor: AP-2 complex subunit mu, F-BAR domain only protein 2, GLYCEROL, ... (4 entities in total)
• Functional Keywords: clathrin-mediated endocytosis (cme), protein recycling, plasma membrane, endocytosis
• Biological source: Rattus norvegicus (Rat); More
• Total number of polymer chains: 2
• Total formula weight: 34083.83

Authors

Zaccai, N.R.,Kelly, B.T.,Evans, P.R.,Owen, D.J. (deposition date: 2021-05-12, release date: 2022-06-01)

• Primary citation: Zaccai, N.R.,Kadlecova, Z.,Dickson, V.K.,Korobchevskaya, K.,Kamenicky, J.,Kovtun, O.,Umasankar, P.K.,Wrobel, A.G.,Kaufman, J.G.G.,Gray, S.R.,Qu, K.,Evans, P.R.,Fritzsche, M.,Sroubek, F.,Honing, S.,Briggs, J.A.G.,Kelly, B.T.,Owen, D.J.,Traub, L.M.; FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P 2 -dependent switch.; Sci Adv, 8:eabn2018-eabn2018, 2022; PubMed: 35486718; DOI: 10.1126/sciadv.abn2018

Experimental method

X-RAY DIFFRACTION (1.65 Å)