7OFP

Apo Structure of Mu2 Adaptin Subunit (Ap50) Of AP2 Clathrin Adaptor

Summary for 7OFP

• Entry DOI: 10.2210/pdb7ofp/pdb
• Descriptor: AP-2 complex subunit mu, GLYCEROL, CITRIC ACID, ... (4 entities in total)
• Functional Keywords: clathrin-mediated endocytosis (cme), yxxphi motif, pi(4, 5)p2, protein recycling, plasma membrane, endocytosis
• Biological source: Rattus norvegicus (Rat)
• Total number of polymer chains: 2
• Total formula weight: 66537.70

Authors

Zaccai, N.R.,Kelly, B.T.,Evans, P.R.,Owen, D.J. (deposition date: 2021-05-05, release date: 2022-06-01, Last modification date: 2024-01-31)

• Primary citation: Zaccai, N.R.,Kadlecova, Z.,Dickson, V.K.,Korobchevskaya, K.,Kamenicky, J.,Kovtun, O.,Umasankar, P.K.,Wrobel, A.G.,Kaufman, J.G.G.,Gray, S.R.,Qu, K.,Evans, P.R.,Fritzsche, M.,Sroubek, F.,Honing, S.,Briggs, J.A.G.,Kelly, B.T.,Owen, D.J.,Traub, L.M.; FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P 2 -dependent switch.; Sci Adv, 8:eabn2018-eabn2018, 2022; PubMed: 35486718; DOI: 10.1126/sciadv.abn2018

Experimental method

X-RAY DIFFRACTION (1.92 Å)