1PYI
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1D66
| DNA RECOGNITION BY GAL4: STRUCTURE OF A PROTEIN/DNA COMPLEX | Descriptor: | CADMIUM ION, DNA (5'-D(*CP*CP*GP*GP*AP*GP*GP*AP*CP*AP*GP*TP*CP*CP*TP*CP*C P*GP*G)-3'), DNA (5'-D(*CP*CP*GP*GP*AP*GP*GP*AP*CP*TP*GP*TP*CP*CP*TP*CP*C P*GP*G)-3'), ... | Authors: | Marmorstein, R, Carey, M, Ptashne, M, Harrison, S.C. | Deposit date: | 1992-03-06 | Release date: | 1992-03-06 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | DNA recognition by GAL4: structure of a protein-DNA complex. Nature, 356, 1992
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1MX2
| Structure of F71N mutant of p18INK4c | Descriptor: | Cyclin-dependent kinase 6 inhibitor | Authors: | Marmorstein, R, Venkataramani, R.N, MacLachlan, T.K, Chai, X, El-Deiery, W.S. | Deposit date: | 2002-10-01 | Release date: | 2002-10-16 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Structure-based design of p18INK4c proteins with increased thermodynamic stability and cell cycle inhibitory activity J.Biol.Chem., 277, 2002
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1MX6
| Structure of p18INK4c (F92N) | Descriptor: | Cyclin-dependent kinase 6 inhibitor | Authors: | Marmorstein, R, Venkataramani, R.N, MacLachlan, T.K, Chai, X, El-Deiry, W.S. | Deposit date: | 2002-10-01 | Release date: | 2002-10-16 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure-based design of p18INK4c proteins with increased thermodynamic stability and cell cycle inhibitory activity J.Biol.Chem., 277, 2002
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1MX4
| Structure of p18INK4c (F82Q) | Descriptor: | Cyclin-dependent kinase 6 inhibitor | Authors: | Marmorstein, R, Venkataramani, R.N, MacLachlan, T.K, Chai, X, El-Deiry, W.S. | Deposit date: | 2002-10-01 | Release date: | 2002-10-16 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure-based design of p18INK4c proteins with increased thermodynamic stability and cell cycle inhibitory activity J.Biol.Chem., 277, 2002
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2QQG
| Hst2 bound to ADP-HPD, acetyllated histone H4 and nicotinamide | Descriptor: | 5'-O-[(S)-{[(S)-{[(2R,3R,4S)-3,4-DIHYDROXYPYRROLIDIN-2-YL]METHOXY}(HYDROXY)PHOSPHORYL]OXY}(HYDROXY)PHOSPHORYL]ADENOSINE, Histone H4, NAD-dependent deacetylase HST2, ... | Authors: | Marmorstein, R, Sanders, B, Zhao, K, Slama, J. | Deposit date: | 2007-07-26 | Release date: | 2007-10-09 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structural basis for nicotinamide inhibition and base exchange in sir2 enzymes. Mol.Cell, 25, 2007
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4ZBJ
| UBN1 peptide bound to H3.3/H4/Asf1 | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, Histone H3, ... | Authors: | Marmorstein, R, Ricketts, M.D, Tang, Y. | Deposit date: | 2015-04-14 | Release date: | 2015-07-15 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.248 Å) | Cite: | Ubinuclein-1 confers histone H3.3-specific-binding by the HIRA histone chaperone complex. Nat Commun, 6, 2015
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5T53
| MOLECULAR BASIS FOR COHESIN ACETYLATION BY ESTABLISHMENT OF SISTER CHROMATID COHESION N-ACETYLTRANSFERASE ESCO1 | Descriptor: | ACETYL COENZYME *A, N-acetyltransferase ESCO1, ZINC ION | Authors: | Marmorstein, R, Rivera-Colon, Y, Liszczak, G.P, Olia, A.S, Maguire, A. | Deposit date: | 2016-08-30 | Release date: | 2016-11-09 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.699 Å) | Cite: | Molecular Basis for Cohesin Acetylation by Establishment of Sister Chromatid Cohesion N-Acetyltransferase ESCO1. J. Biol. Chem., 291, 2016
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2I32
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2OD9
| Structural Basis for Nicotinamide Inhibition and Base Exchange in Sir2 Enzymes | Descriptor: | 5'-O-[(S)-{[(S)-{[(2R,3R,4S)-3,4-DIHYDROXYPYRROLIDIN-2-YL]METHOXY}(HYDROXY)PHOSPHORYL]OXY}(HYDROXY)PHOSPHORYL]ADENOSINE, H4 peptide, NAD-dependent deacetylase HST2, ... | Authors: | Marmorstein, R, Sanders, B.D. | Deposit date: | 2006-12-21 | Release date: | 2007-02-27 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structural basis for nicotinamide inhibition and base exchange in sir2 enzymes. Mol.Cell, 25, 2007
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2QQF
| Hst2 bound to ADP-HPD and Acetylated histone H4 | Descriptor: | 5'-O-[(S)-{[(S)-{[(2R,3R,4S)-3,4-DIHYDROXYPYRROLIDIN-2-YL]METHOXY}(HYDROXY)PHOSPHORYL]OXY}(HYDROXY)PHOSPHORYL]ADENOSINE, Histone H4, NAD-dependent deacetylase HST2, ... | Authors: | Marmorstein, R, Sanders, B.D, Zhao, K, Slama, J. | Deposit date: | 2007-07-26 | Release date: | 2007-10-09 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural basis for nicotinamide inhibition and base exchange in sir2 enzymes. Mol.Cell, 25, 2007
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7STX
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2FQ3
| Structure and function of the SWIRM domain, a conserved protein module found in chromatin regulatory complexes | Descriptor: | Transcription regulatory protein SWI3 | Authors: | Da, G, Lenkart, J, Zhao, K, Shiekhattar, R, Cairns, B.R, Marmorstein, R. | Deposit date: | 2006-01-17 | Release date: | 2006-02-07 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structure and function of the SWIRM domain, a conserved protein module found in chromatin regulatory complexes Proc.Natl.Acad.Sci.Usa, 103, 2006
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3TO7
| Crystal structure of yeast Esa1 HAT domain bound to coenzyme A with active site lysine acetylated | Descriptor: | CACODYLIC ACID, COENZYME A, GLYCEROL, ... | Authors: | Yuan, H, Ding, E.C, Marmorstein, R. | Deposit date: | 2011-09-04 | Release date: | 2011-11-09 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | MYST protein acetyltransferase activity requires active site lysine autoacetylation. Embo J., 31, 2011
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3TOB
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3TO9
| Crystal structure of yeast Esa1 E338Q HAT domain bound to coenzyme A with active site lysine acetylated | Descriptor: | 1,2-ETHANEDIOL, CACODYLIC ACID, COENZYME A, ... | Authors: | Yuan, H, Ding, E.C, Marmorstein, R. | Deposit date: | 2011-09-04 | Release date: | 2011-11-09 | Last modified: | 2012-01-18 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | MYST protein acetyltransferase activity requires active site lysine autoacetylation. Embo J., 31, 2011
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5J8C
| Human MOF C316S, E350Q crystal structure | Descriptor: | CHLORIDE ION, Histone acetyltransferase KAT8, SODIUM ION, ... | Authors: | McCullough, C.E, Marmorstein, R. | Deposit date: | 2016-04-07 | Release date: | 2016-07-20 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.17 Å) | Cite: | Structural and Functional Role of Acetyltransferase hMOF K274 Autoacetylation. J.Biol.Chem., 291, 2016
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5J8F
| Human MOF K274P crystal structure | Descriptor: | CHLORIDE ION, Histone acetyltransferase KAT8, ZINC ION | Authors: | McCullough, C.E, Marmorstein, R. | Deposit date: | 2016-04-07 | Release date: | 2016-07-20 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural and Functional Role of Acetyltransferase hMOF K274 Autoacetylation. J.Biol.Chem., 291, 2016
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2GEQ
| Crystal Structure of a p53 Core Dimer Bound to DNA | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5'-D(*GP*CP*GP*TP*GP*AP*GP*CP*AP*TP*GP*CP*TP*CP*AP*C)-3', Cellular tumor antigen p53, ... | Authors: | Ho, W.C, Fitzgerald, M.X, Marmorstein, R. | Deposit date: | 2006-03-20 | Release date: | 2006-05-23 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure of the p53 Core Domain Dimer Bound to DNA. J.Biol.Chem., 281, 2006
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2QIY
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6O07
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1SZD
| Structural basis for nicotinamide cleavage and ADP-ribose transfer by NAD+-dependent Sir2 histone/protein deacetylases | Descriptor: | ADENOSINE-5-DIPHOSPHORIBOSE, CHLORIDE ION, GLYCEROL, ... | Authors: | Zhao, K, Harshaw, R, Chai, X, Marmorstein, R. | Deposit date: | 2004-04-05 | Release date: | 2004-06-15 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structural basis for nicotinamide cleavage and ADP-ribose transfer by NAD(+)-dependent Sir2 histone/protein deacetylases. Proc.Natl.Acad.Sci.Usa, 101, 2004
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2R7G
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2RC4
| Crystal Structure of the HAT domain of the human MOZ protein | Descriptor: | ACETYL COENZYME *A, Histone acetyltransferase MYST3, ZINC ION | Authors: | Holbert, M.A, Sikorski, T, Snowflack, D, Marmorstein, R. | Deposit date: | 2007-09-19 | Release date: | 2007-11-13 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | The human monocytic leukemia zinc finger histone acetyltransferase domain contains DNA-binding activity implicated in chromatin targeting. J.Biol.Chem., 282, 2007
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1SZC
| Structural basis for nicotinamide cleavage and ADP-ribose transfer by NAD+-dependent Sir2 histone/protein deacetylases | Descriptor: | CARBA-NICOTINAMIDE-ADENINE-DINUCLEOTIDE, CHLORIDE ION, GLYCEROL, ... | Authors: | Zhao, K, Harshaw, R, Chai, X, Marmorstein, R. | Deposit date: | 2004-04-05 | Release date: | 2004-06-15 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structural basis for nicotinamide cleavage and ADP-ribose transfer by NAD(+)-dependent Sir2 histone/protein deacetylases. Proc.Natl.Acad.Sci.Usa, 101, 2004
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