2R7G

Structure of the retinoblastoma protein pocket domain in complex with adenovirus E1A CR1 domain

Summary for 2R7G

Entry DOI	10.2210/pdb2r7g/pdb
Descriptor	Retinoblastoma-associated protein, Early E1A 32 kDa protein, SULFATE ION, ... (4 entities in total)
Functional Keywords	retinoblastoma protein, e1a, e2f displacement, transcription repressor, cell cycle
Biological source	Homo sapiens (human) More
Cellular location	Nucleus : P06400 Host nucleus : P03255
Total number of polymer chains	5
Total formula weight	85243.78
Authors	Liu, X.,Marmorstein, R. (deposition date: 2007-09-07, release date: 2007-10-02, Last modification date: 2024-02-21)
Primary citation	Liu, X.,Marmorstein, R. Structure of the retinoblastoma protein bound to adenovirus E1A reveals the molecular basis for viral oncoprotein inactivation of a tumor suppressor Genes Dev., 21:2711-2716, 2007 Cited by PubMed: 17974914 DOI: 10.1101/gad.1590607 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.671 Å)

Structure validation