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3HCT
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BU of 3hct by Molmil
Crystal structure of TRAF6 in complex with Ubc13 in the P1 space group
Descriptor: TNF receptor-associated factor 6, Ubiquitin-conjugating enzyme E2 N, ZINC ION
Authors:Yin, Q, Lin, S.-C, Lamothe, B, Lu, M, Lo, Y.-C, Hura, G, Zheng, L, Rich, R.L, Campos, A.D, Myszka, D.G, Lenardo, M.J, Darnay, B.G, Wu, H.
Deposit date:2009-05-06
Release date:2009-05-26
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:E2 interaction and dimerization in the crystal structure of TRAF6.
Nat.Struct.Mol.Biol., 16, 2009
8YBX
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BU of 8ybx by Molmil
Structure of the FADD/Caspase-8/cFLIP death effector domain assembly
Descriptor: CASP8 and FADD-like apoptosis regulator subunit p43, Caspase-8 subunit p10, FAS-associated death domain protein
Authors:Lin, S.-C, Yang, C.-Y.
Deposit date:2024-02-16
Release date:2024-05-15
Method:ELECTRON MICROSCOPY (3.68 Å)
Cite:Deciphering DED assembly mechanisms in FADD-procaspase-8-cFLIP complexes regulating apoptosis.
Nat Commun, 15, 2024
8YD7
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BU of 8yd7 by Molmil
Structure of FADD/Caspase-8/cFLIP death effector domain assembly
Descriptor: CASP8 and FADD-like apoptosis regulator subunit p12, Caspase-8, FAS-associated death domain protein, ...
Authors:Lin, S.-C, Yang, C.-Y.
Deposit date:2024-02-19
Release date:2024-05-15
Method:X-RAY DIFFRACTION (3.32 Å)
Cite:Deciphering DED assembly mechanisms in FADD-procaspase-8-cFLIP complexes regulating apoptosis.
Nat Commun, 15, 2024
8YD8
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BU of 8yd8 by Molmil
Structure of FADD/Caspase-8/cFLIP death effector domain assembly
Descriptor: CASP8 and FADD-like apoptosis regulator subunit p43, Caspase-8, FAS-associated death domain protein
Authors:Lin, S.-C, Yang, C.-Y.
Deposit date:2024-02-19
Release date:2024-05-15
Method:X-RAY DIFFRACTION (3.11 Å)
Cite:Deciphering DED assembly mechanisms in FADD-procaspase-8-cFLIP complexes regulating apoptosis.
Nat Commun, 15, 2024
3MOP
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BU of 3mop by Molmil
The ternary Death Domain complex of MyD88, IRAK4, and IRAK2
Descriptor: Interleukin-1 receptor-associated kinase 4, Interleukin-1 receptor-associated kinase-like 2, Myeloid differentiation primary response protein MyD88
Authors:Lin, S.-C, Lo, Y.-C, Wu, H.
Deposit date:2010-04-23
Release date:2010-06-02
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Helical assembly in the MyD88-IRAK4-IRAK2 complex in TLR/IL-1R signalling.
Nature, 465, 2010
1FT4
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BU of 1ft4 by Molmil
PHOTOCHEMICALLY-ENHANCED BINDING OF SMALL MOLECULES TO THE TUMOR NECROSIS FACTOR RECEPTOR-1
Descriptor: 5-(3-MORPHOLIN-4-YL-PROPYL)-2-(3-NITRO-PHENYL)-4-THIOXO-4,5-DIHYDRO-1-THIA-3B,5-DIAZA-CYCLOPENTA[A]PENTALEN-6-ONE, SOLUBLE TUMOR NECROSIS FACTOR RECEPTOR 1
Authors:Muckelbauer, J.K, Chang, C.-H.
Deposit date:2000-09-11
Release date:2001-10-12
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Photochemically enhanced binding of small molecules to the tumor necrosis factor receptor-1 inhibits the binding of TNF-alpha.
Proc.Natl.Acad.Sci.USA, 98, 2001
2POI
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BU of 2poi by Molmil
Crystal structure of XIAP BIR1 domain (I222 form)
Descriptor: Baculoviral IAP repeat-containing protein 4, ZINC ION
Authors:Lin, S.
Deposit date:2007-04-26
Release date:2007-07-03
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:XIAP Induces NF-kappaB Activation via the BIR1/TAB1 Interaction and BIR1 Dimerization.
Mol.Cell, 26, 2007
2POM
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BU of 2pom by Molmil
TAB1 with manganese ion
Descriptor: MANGANESE (II) ION, Mitogen-activated protein kinase kinase kinase 7-interacting protein 1
Authors:Lin, S.C.
Deposit date:2007-04-26
Release date:2007-07-03
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:XIAP Induces NF-kappaB Activation via the BIR1/TAB1 Interaction and BIR1 Dimerization.
Mol.Cell, 26, 2007
2POP
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BU of 2pop by Molmil
The Crystal Structure of TAB1 and BIR1 complex
Descriptor: Baculoviral IAP repeat-containing protein 4, Mitogen-activated protein kinase kinase kinase 7-interacting protein 1, ZINC ION
Authors:Lin, S.C.
Deposit date:2007-04-27
Release date:2007-07-03
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:XIAP Induces NF-kappaB Activation via the BIR1/TAB1 Interaction and BIR1 Dimerization.
Mol.Cell, 26, 2007
2QRA
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BU of 2qra by Molmil
Crystal structure of XIAP BIR1 domain (P21 form)
Descriptor: Baculoviral IAP repeat-containing protein 4, ETHANOL, ZINC ION
Authors:Lin, S.-C.
Deposit date:2007-07-27
Release date:2007-09-18
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of the BIR1 domain of XIAP in two crystal forms
J.Mol.Biol., 372, 2007
4KBY
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BU of 4kby by Molmil
mSTING/c-di-GMP
Descriptor: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), Stimulator of interferon genes protein
Authors:Chin, K.H, Su, Y.C, Tu, J.L, Chou, S.H.
Deposit date:2013-04-24
Release date:2013-05-29
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.36 Å)
Cite:Novel c-di-GMP recognition modes of the mouse innate immune adaptor protein STING
Acta Crystallogr.,Sect.D, 69, 2013
4KC0
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BU of 4kc0 by Molmil
mSTING
Descriptor: Stimulator of interferon genes protein
Authors:Chin, K.H, Su, Y.C, Tu, J.L, Chou, S.H.
Deposit date:2013-04-24
Release date:2013-05-29
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Novel c-di-GMP recognition modes of the mouse innate immune adaptor protein STING
Acta Crystallogr.,Sect.D, 69, 2013
5GYJ
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BU of 5gyj by Molmil
Structure of catalytically active sortase from Clostridium difficile
Descriptor: Putative peptidase C60B, sortase B
Authors:Yin, J.-C, Fei, C.-H, Hsiao, Y.-Y, Nix, J.C, Huang, I.-H, Wang, S.
Deposit date:2016-09-22
Release date:2017-01-04
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.801 Å)
Cite:Structural Insights into Substrate Recognition by Clostridium difficile Sortase.
Front Cell Infect Microbiol, 6, 2016
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