2XFE
| vCBM60 in complex with galactobiose | Descriptor: | CALCIUM ION, CARBOHYDRATE BINDING MODULE, beta-D-galactopyranose-(1-4)-beta-D-galactopyranose | Authors: | Montanier, C, Flint, J.E, Bolam, D.N, Xie, H, Liu, Z, Rogowski, A, Weiner, D.P, Nurizzo, D, Roberts, S.M, Turkenburg, J.P, Davies, G.J, Gilbert, H.J. | Deposit date: | 2010-05-21 | Release date: | 2010-06-16 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | Circular Permutation Provides an Evolutionary Link between Two Families of Calcium-Dependent Carbohydrate Binding Modules. J.Biol.Chem., 285, 2010
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2XHJ
| Circular permutation provides an evolutionary link between two families of calcium-dependent carbohydrate binding modules. SeMet form of vCBM60. | Descriptor: | CALCIUM ION, CALCIUM-DEPENDENT CARBOHYDRATE BINDING MODULE | Authors: | Montanier, C, Flint, J.E, Bolam, D.N, Xie, H, Liu, Z, Rogowski, A, Weiner, D, Ratnaparkhe, S, Nurizzo, D, Roberts, S.M, Turkenburg, J.P, Davies, G.J, Gilbert, H.J. | Deposit date: | 2010-06-16 | Release date: | 2010-07-21 | Last modified: | 2019-05-08 | Method: | X-RAY DIFFRACTION (1.73 Å) | Cite: | Circular Permutation Provides an Evolutionary Link between Two Families of Calcium-Dependent Carbohydrate Binding Modules J.Biol.Chem., 285, 2010
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1H5P
| Solution structure of the human Sp100b SAND domain by heteronuclear NMR. | Descriptor: | NUCLEAR AUTOANTIGEN SP100-B | Authors: | Bottomley, M.J, Liu, Z, Collard, M.W, Huggenvik, J.I, Gibson, T.J, Sattler, M. | Deposit date: | 2001-05-24 | Release date: | 2001-07-06 | Last modified: | 2018-03-28 | Method: | SOLUTION NMR | Cite: | The SAND domain structure defines a novel DNA-binding fold in transcriptional regulation. Nat. Struct. Biol., 8, 2001
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2XHH
| Circular permutation provides an evolutionary link between two families of calcium-dependent carbohydrate binding modules | Descriptor: | (2S)-2-hydroxybutanedioic acid, CALCIUM ION, CARBOHYDRATE BINDING MODULE | Authors: | Montanier, C, Flint, J.E, Bolam, D.N, Xie, H, Liu, Z, Rogowski, A, Weiner, D, Ratnaparkhe, S, Nurizzo, D, Roberts, S.M, Turkenburg, J.P, Davies, G.J, Gilbert, H.J. | Deposit date: | 2010-06-16 | Release date: | 2010-07-21 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Circular Permutation Provides an Evolutionary Link between Two Families of Calcium-Dependent Carbohydrate Binding Modules J.Biol.Chem., 285, 2010
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2XFD
| vCBM60 in complex with cellobiose | Descriptor: | CALCIUM ION, CARBOHYDRATE BINDING MODULE, GLYCEROL, ... | Authors: | Montanier, C, Flint, J.E, Bolam, D.N, Xie, H, Liu, Z, Rogowski, A, Weiner, D.P, Nurizzo, D, Roberts, S.M, Turkenburg, J.P, Davies, G.J, Gilbert, H.J. | Deposit date: | 2010-05-21 | Release date: | 2010-06-16 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.19 Å) | Cite: | Circular Permutation Provides an Evolutionary Link between Two Families of Calcium-Dependent Carbohydrate Binding Modules. J.Biol.Chem., 285, 2010
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8VQ3
| CDK2-CyclinE1 in complex with allosteric inhibitor I-198. | Descriptor: | (8R)-N-[(2S,3R)-3-(cyclohexylmethoxy)-1-(morpholin-4-yl)-1-oxobutan-2-yl]-2-[(1S)-2,2-dimethylcyclopropane-1-carbonyl]-6-(1,3-thiazole-5-carbonyl)-2,6-diazaspiro[3.4]octane-8-carboxamide, Cyclin-dependent kinase 2, G1/S-specific cyclin-E1 | Authors: | Hirschi, M, Johnson, E, Zhang, Y, Liu, Z, Brodsky, O, Won, S.J, Nagata, A, Petroski, M.D, Majmudar, J.D, Niessen, S, VanArsdale, T, Gilbert, A.M, Hayward, M.M, Stewart, A.E, Nager, A.R, Melillo, B, Cravatt, B. | Deposit date: | 2024-01-17 | Release date: | 2024-01-31 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.84 Å) | Cite: | Expanding the ligandable proteome by paralog hopping with covalent probes. Biorxiv, 2024
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8VQ4
| CDK2-CyclinE1 in complex with allosteric inhibitor I-125A. | Descriptor: | (8R)-6-(1-benzyl-1H-pyrazole-4-carbonyl)-N-[(2S,3R)-3-(2-cyclohexylethoxy)-1-(methylamino)-1-oxobutan-2-yl]-2-[(1S)-2,2-dimethylcyclopropane-1-carbonyl]-2,6-diazaspiro[3.4]octane-8-carboxamide, Cyclin-dependent kinase 2, G1/S-specific cyclin-E1 | Authors: | Hirschi, M, Johnson, E, Zhang, Y, Liu, Z, Brodsky, O, Won, S.J, Nagata, A, Petroski, M.D, Majmudar, J.D, Niessen, S, VanArsdale, T, Gilbert, A.M, Hayward, M.M, Stewart, A.E, Nager, A.R, Melillo, B, Cravatt, B. | Deposit date: | 2024-01-17 | Release date: | 2024-01-31 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Expanding the ligandable proteome by paralog hopping with covalent probes. Biorxiv, 2024
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3NGM
| Crystal structure of lipase from Gibberella zeae | Descriptor: | Extracellular lipase | Authors: | Lou, Z.Y, Li, M, Sun, Y.N, Liu, Y, Liu, Z, Rao, Z.H. | Deposit date: | 2010-06-12 | Release date: | 2011-05-25 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structure of a secreted lipase from Gibberella zeae reveals a novel "double-lock" mechanism Protein Cell, 1, 2010
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1MOT
| NMR Structure Of Extended Second Transmembrane Domain Of Glycine Receptor alpha1 Subunit in SDS Micelles | Descriptor: | Glycine Receptor alpha-1 CHAIN | Authors: | Yushmanov, V.E, Mandal, P.K, Liu, Z, Tang, P, Xu, Y. | Deposit date: | 2002-09-09 | Release date: | 2003-09-23 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | NMR Structure and Backbone Dynamics of the Extended Second Transmembrane Domain of the Human Neuronal Glycine Receptor Alpha1 Subunit Biochemistry, 42, 2003
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1W9G
| Structure of ERH (Enhencer of Rudimentary Gene) | Descriptor: | ENHANCER OF RUDIMENTARY HOMOLOG | Authors: | Wan, C, Tempel, W, Liu, Z, Wang, B.-C, Rose, R.B. | Deposit date: | 2004-10-13 | Release date: | 2005-04-06 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure of the Conserved Transcriptional Repressor Enhancer of Rudimentary Homolog Biochemistry, 44, 2005
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2GR9
| Crystal structure of P5CR complexed with NADH | Descriptor: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, GLUTAMIC ACID, Pyrroline-5-carboxylate reductase 1 | Authors: | Meng, Z, Lou, Z, Liu, Z, Rao, Z. | Deposit date: | 2006-04-23 | Release date: | 2006-10-03 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Crystal structure of human pyrroline-5-carboxylate reductase J.Mol.Biol., 359, 2006
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2GRA
| crystal structure of Human Pyrroline-5-carboxylate Reductase complexed with nadp | Descriptor: | GLUTAMIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Pyrroline-5-carboxylate reductase 1 | Authors: | Meng, Z, Lou, Z, Liu, Z, Rao, Z. | Deposit date: | 2006-04-23 | Release date: | 2006-10-03 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Crystal structure of human pyrroline-5-carboxylate reductase J.Mol.Biol., 359, 2006
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1P0R
| Solution Structure of UBL5 a human Ubiquitin-Like Protein | Descriptor: | ubiquitin-like 5 | Authors: | McNally, T, Huang, Q, Janis, R.S, Liu, Z, Olejniczak, E.T, Reilly, R.M. | Deposit date: | 2003-04-10 | Release date: | 2003-10-28 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | Structural analysis of UBL5, a novel ubiquitin-like modifier Protein Sci., 12, 2003
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2GER
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1XOX
| SOLUTION STRUCTURE OF HUMAN SURVIVIN | Descriptor: | Apoptosis inhibitor survivin, ZINC ION | Authors: | Sun, C, Nettesheim, D, Liu, Z, Olejniczak, E.T. | Deposit date: | 2004-10-07 | Release date: | 2005-01-18 | Last modified: | 2022-03-02 | Method: | SOLUTION NMR | Cite: | Solution structure of human survivin and its binding interface with smac/diablo Biochemistry, 44, 2005
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6PZP
| Crystal structure of caspase-1 in complex with VX-765 | Descriptor: | Caspase-1, N-(4-amino-3-chlorobenzene-1-carbonyl)-3-methyl-L-valyl-N-[(2S)-1-carboxy-3-oxopropan-2-yl]-L-prolinamide | Authors: | Yang, J, Liu, Z, Xiao, T.S. | Deposit date: | 2019-08-01 | Release date: | 2020-08-05 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | Crystal structure of caspase-1 in complex with VX-765 To Be Published
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1ZGH
| Methionyl-tRNA formyltransferase from Clostridium thermocellum | Descriptor: | Methionyl-tRNA formyltransferase, UNKNOWN ATOM OR ION | Authors: | Yang, H, Kataeva, I, Xu, H, Zhao, M, Chang, J, Liu, Z, Chen, L, Tempel, W, Habel, J, Zhou, W, Lee, D, Lin, D, Chang, S, Arendall III, W.B, Richardson, J.S, Richardson, D.C, Rose, J.P, Wang, B, Southeast Collaboratory for Structural Genomics (SECSG) | Deposit date: | 2005-04-21 | Release date: | 2005-05-03 | Last modified: | 2017-10-11 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Methionyl-tRNA formyltransferase from Clostridium thermocellum To be published
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5CRZ
| Crystal Structure of the first bromodomain of human BRD4 in complex with benzo[cd]indol-2(1H)-one ligand | Descriptor: | 1,2-ETHANEDIOL, 2-chloro-N-(1-ethyl-2-oxo-1,2-dihydrobenzo[cd]indol-6-yl)-4-fluorobenzenesulfonamide, Bromodomain-containing protein 4, ... | Authors: | Zhang, Y, Song, M, Liu, Z, Xue, X, Xu, Y. | Deposit date: | 2015-07-23 | Release date: | 2016-01-13 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.12 Å) | Cite: | Discovery of Benzo[cd]indol-2(1H)-ones as Potent and Specific BET Bromodomain Inhibitors: Structure-Based Virtual Screening, Optimization, and Biological Evaluation J.Med.Chem., 59, 2016
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5DX4
| Crystal Structure of the first bromodomain of human BRD4 in complex with benzo[cd]indol-2(1H)-one ligand | Descriptor: | 1,2-ETHANEDIOL, 5-bromo-N-(1-ethyl-2-oxo-1,2-dihydrobenzo[cd]indol-6-yl)-2-methoxybenzenesulfonamide, Bromodomain-containing protein 4, ... | Authors: | Zhang, Y, Song, M, Liu, Z, Xue, X, Xu, Y. | Deposit date: | 2015-09-23 | Release date: | 2016-01-13 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Discovery of Benzo[cd]indol-2(1H)-ones as Potent and Specific BET Bromodomain Inhibitors: Structure-Based Virtual Screening, Optimization, and Biological Evaluation J.Med.Chem., 59, 2016
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4Y7K
| Structure of an archaeal mechanosensitive channel in closed state | Descriptor: | Large conductance mechanosensitive channel protein,Riboflavin synthase | Authors: | Li, J, Liu, Z. | Deposit date: | 2015-02-15 | Release date: | 2015-08-26 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Mechanical coupling of the multiple structural elements of the large-conductance mechanosensitive channel during expansion Proc.Natl.Acad.Sci.USA, 112, 2015
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3HAG
| Crystal structure of the Hepatitis E Virus-like Particle | Descriptor: | Capsid protein | Authors: | Guu, T.S.Y, Liu, Z, Ye, Q, Mata, D.A, Li, K, Yin, C, Zhang, J, Tao, Y.J. | Deposit date: | 2009-05-01 | Release date: | 2009-09-01 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Structure of the hepatitis E virus-like particle suggests mechanisms for virus assembly and receptor binding. Proc.Natl.Acad.Sci.USA, 106, 2009
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3J7W
| Capsid Expansion Mechanism Of Bacteriophage T7 Revealed By Multi-State Atomic Models Derived From Cryo-EM Reconstructions | Descriptor: | Major capsid protein 10A | Authors: | Guo, F, Liu, Z, Fang, P.A, Zhang, Q, Wright, E.T, Wu, W, Zhang, C, Vago, F, Ren, Y, Jakata, J, Chiu, W, Serwer, P, Jiang, W. | Deposit date: | 2014-08-12 | Release date: | 2014-10-15 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Capsid expansion mechanism of bacteriophage T7 revealed by multistate atomic models derived from cryo-EM reconstructions. Proc.Natl.Acad.Sci.USA, 111, 2014
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3J9Z
| Activation of GTP Hydrolysis in mRNA-tRNA Translocation by Elongation Factor G | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Li, W, Liu, Z, Koripella, R.K, Langlois, R, Sanyal, S, Frank, J. | Deposit date: | 2015-03-27 | Release date: | 2015-07-01 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Activation of GTP hydrolysis in mRNA-tRNA translocation by elongation factor G. Sci Adv, 1, 2015
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6A6B
| cryo-em structure of alpha-synuclein fiber | Descriptor: | Alpha-synuclein | Authors: | Li, Y.W, Zhao, C.Y, Luo, F, Liu, Z, Gui, X, Luo, Z, Zhang, X, Li, D, Liu, C, Li, X. | Deposit date: | 2018-06-27 | Release date: | 2018-07-11 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.07 Å) | Cite: | Amyloid fibril structure of alpha-synuclein determined by cryo-electron microscopy Cell Res., 28, 2018
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5T43
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