4P8E
| Structure of ribB complexed with substrate (Ru5P) and metal ions | Descriptor: | 1,2-ETHANEDIOL, 3,4-dihydroxy-2-butanone 4-phosphate synthase, RIBULOSE-5-PHOSPHATE, ... | Authors: | Islam, Z, Kumar, A, Singh, S, Salmon, L, Karthikeyan, S. | Deposit date: | 2014-03-31 | Release date: | 2015-03-25 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.04 Å) | Cite: | Structural Basis for Competitive Inhibition of 3,4-Dihydroxy-2-butanone-4-phosphate Synthase from Vibrio cholerae. J.Biol.Chem., 290, 2015
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4P6C
| Structure of ribB complexed with inhibitor 4PEH | Descriptor: | 3,4-dihydroxy-2-butanone 4-phosphate synthase, 4-PHOSPHO-D-ERYTHRONOHYDROXAMIC ACID | Authors: | Islam, Z, Kumar, A, Singh, S, Salmon, L, Karthikeyan, S. | Deposit date: | 2014-03-24 | Release date: | 2015-03-25 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Structural Basis for Competitive Inhibition of 3,4-Dihydroxy-2-butanone-4-phosphate Synthase from Vibrio cholerae. J.Biol.Chem., 290, 2015
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4P6D
| Structure of ribB complexed with PO4 ion | Descriptor: | 1,2-ETHANEDIOL, 3,4-dihydroxy-2-butanone 4-phosphate synthase, PHOSPHATE ION | Authors: | Islam, Z, Kumar, A, Singh, S, Salmon, L, Karthikeyan, S. | Deposit date: | 2014-03-24 | Release date: | 2015-03-25 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.59 Å) | Cite: | Structural Basis for Competitive Inhibition of 3,4-Dihydroxy-2-butanone-4-phosphate Synthase from Vibrio cholerae. J.Biol.Chem., 290, 2015
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4P6P
| Structure of ribB complexed with inhibitor (4PEH) and metal ions | Descriptor: | 3,4-dihydroxy-2-butanone 4-phosphate synthase, 4-PHOSPHO-D-ERYTHRONOHYDROXAMIC ACID, ZINC ION | Authors: | Islam, Z, Kumar, A, Singh, S, Salmon, L, Karthikeyan, S. | Deposit date: | 2014-03-25 | Release date: | 2015-03-25 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.862 Å) | Cite: | Structural Basis for Competitive Inhibition of 3,4-Dihydroxy-2-butanone-4-phosphate Synthase from Vibrio cholerae. J.Biol.Chem., 290, 2015
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4P77
| Structure of ribB complexed with substrate Ru5P | Descriptor: | 3,4-dihydroxy-2-butanone 4-phosphate synthase, GLYCEROL, RIBULOSE-5-PHOSPHATE | Authors: | Islam, Z, Kumar, A, Singh, S, Salmon, L, Karthikeyan, S. | Deposit date: | 2014-03-26 | Release date: | 2015-03-25 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.04 Å) | Cite: | Structural Basis for Competitive Inhibition of 3,4-Dihydroxy-2-butanone-4-phosphate Synthase from Vibrio cholerae. J.Biol.Chem., 290, 2015
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4P8J
| Structure of ribB | Descriptor: | 3,4-dihydroxy-2-butanone 4-phosphate synthase, GLYCEROL | Authors: | Islam, Z, Kumar, A, Singh, S, Salmon, L, Karthikeyan, S. | Deposit date: | 2014-03-31 | Release date: | 2015-03-25 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | Structural Basis for Competitive Inhibition of 3,4-Dihydroxy-2-butanone-4-phosphate Synthase from Vibrio cholerae. J.Biol.Chem., 290, 2015
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289D
| TARGETING THE MINOR GROOVE OF DNA: CRYSTAL STRUCTURES OF TWO COMPLEXES BETWEEN FURAN DERIVATIVES OF BERENIL AND THE DNA DODECAMER D(CGCGAATTCGCG)2 | Descriptor: | 2,5-BIS{[4-(N-CYCLOPROPYLDIAMINOMETHYL)PHENYL]}FURAN, DNA (5'-R(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3') | Authors: | Trent, J.O, Clark, G.R, Kumar, A, Wilson, W.D, Boykin, D.W, Hall, J.E, Tidwell, R.R, Blagburn, B.L, Neidle, S. | Deposit date: | 1996-10-10 | Release date: | 1996-12-17 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Targeting the minor groove of DNA: crystal structures of two complexes between furan derivatives of berenil and the DNA dodecamer d(CGCGAATTCGCG)2. J.Med.Chem., 39, 1996
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7F7D
| Crystal structure of Non-specific class-C acid phosphatase from Sphingobium sp. RSMS bound to Adenosine at pH 5.5 | Descriptor: | ADENOSINE, Acid phosphatase, DI(HYDROXYETHYL)ETHER, ... | Authors: | Gaur, N.K, Kumar, A, Sunder, S, Mukhopadhyaya, R, Makde, R.D. | Deposit date: | 2021-06-28 | Release date: | 2022-07-06 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Non-Specific Class-c acidphosphatase from Sphingobium sp. RSMS To Be Published
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7F7A
| Crystal structure of Non-specific class-C acid phosphatase from Sphingobium sp. RSMS bound to Adenine at pH 9 | Descriptor: | ADENINE, Acid phosphatase, MAGNESIUM ION | Authors: | Gaur, N.K, Kumar, A, Sunder, S, Mukhopadhyaya, R, Makde, R.D. | Deposit date: | 2021-06-28 | Release date: | 2022-07-06 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Non-Specific Class-c acidphosphatase from Sphingobium sp. RSMS To Be Published
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7F7B
| Crystal structure of Non-specific class-C acid phosphatase from Sphingobium sp. RSMS bound to BIS-TRIS at pH 5.5 | Descriptor: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Acid phosphatase, MAGNESIUM ION, ... | Authors: | Gaur, N.K, Kumar, A, Sunder, S, Mukhopadhyaya, R, Makde, R.D. | Deposit date: | 2021-06-28 | Release date: | 2022-07-06 | Method: | X-RAY DIFFRACTION (2.34 Å) | Cite: | Non-Specific Class-c acidphosphatase from Sphingobium sp. RSMS To Be Published
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7F7C
| Crystal structure of Non-specific class-C acid phosphatase from Sphingobium sp. RSMS bound to Adenosine at pH 5.5 | Descriptor: | ADENOSINE, Acid phosphatase, MAGNESIUM ION, ... | Authors: | Gaur, N.K, Kumar, A, Sunder, S, Mukhopadhyaya, R, Makde, R.D. | Deposit date: | 2021-06-28 | Release date: | 2022-07-06 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Non-Specific Class-c acidphosphatase from Sphingobium sp. RSMS To Be Published
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7FCR
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7FCS
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2NDC
| Solution Structure of BMAP-28(1-18) | Descriptor: | Cathelicidin-5 | Authors: | Agadi, N, Kumar, A. | Deposit date: | 2016-05-12 | Release date: | 2017-09-13 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structure, Function And Membrane Interaction Studies Of Two Synthetic Antimicrobial Peptides Using Solution And Solid State NMR To be Published
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2NDE
| Solution Structure of Mutant of BMAP-28(1-18) | Descriptor: | Cathelicidin-5 | Authors: | Agadi, N, Kumar, A. | Deposit date: | 2016-05-12 | Release date: | 2017-09-13 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structure, Function And Membrane Interaction Studies of Two Synthetic Peptides Using Solution And Solid State NMR To be Published
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2L94
| Structure of the HIV-1 frameshift site RNA bound to a small molecule inhibitor of viral replication | Descriptor: | N'-{(Z)-amino[4-(amino{[3-(dimethylammonio)propyl]iminio}methyl)phenyl]methylidene}-N,N-dimethylpropane-1,3-diaminium, RNA_(45-MER) | Authors: | Marcheschi, R.J, Tonelli, M, Kumar, A, Butcher, S.E. | Deposit date: | 2011-01-29 | Release date: | 2011-06-15 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structure of the HIV-1 Frameshift Site RNA Bound to a Small Molecule Inhibitor of Viral Replication. Acs Chem.Biol., 6, 2011
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5BOK
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2C8V
| Insights into the role of nucleotide-dependent conformational change in nitrogenase catalysis: Structural characterization of the nitrogenase Fe protein Leu127 deletion variant with bound MgATP | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, FE2/S2 (INORGANIC) CLUSTER, MAGNESIUM ION, ... | Authors: | Sen, S, Krishnakumar, A, McClead, J, Johnson, M.K, Seefeldt, L.C, Szilagyi, R.K, Peters, J.W. | Deposit date: | 2005-12-08 | Release date: | 2006-06-01 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Insights Into the Role of Nucleotide-Dependent Conformational Change in Nitrogenase Catalysis: Structural Characterization of the Nitrogenase Fe Protein Leu127 Deletion Variant with Bound Mgatp. J.Inorg.Biochem., 100, 2006
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2MHC
| NMR structure of the catalytic domain of the large serine resolvase TnpX | Descriptor: | TnpX | Authors: | Headey, S.J, Sivakumaran, A, Adams, V, Rodgers, A.J.W, Rood, J.I, Scanlon, M.J, Wilce, M.C.J. | Deposit date: | 2013-11-20 | Release date: | 2014-11-26 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution Structure and DNA Binding of the Catalytic of the Large Serine Resolvase Tnpx To be Published
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4V3J
| Structural and functional characterization of a novel monotreme- specific protein from the milk of the platypus | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, MONOTREME LACTATING PROTEIN | Authors: | Kumar, A, Newman, J, Polekina, G, Adams, T.E, Sharp, J.A, Peat, T.S, Nicholas, K.R. | Deposit date: | 2014-10-20 | Release date: | 2016-01-20 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | Structural characterization of a novel monotreme-specific protein with antimicrobial activity from the milk of the platypus. Acta Crystallogr F Struct Biol Commun, 74, 2018
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8ILU
| Crystal structure of mouse Galectin-3 in complex with small molecule inhibitor | Descriptor: | (2R,3R,4R,5R,6S)-2-(hydroxymethyl)-6-[2-(2-methyl-1,3-benzothiazol-6-yl)-1,2,4-triazol-3-yl]-4-[4-[3,4,5-tris(fluoranyl)phenyl]-1,2,3-triazol-1-yl]oxane-3,5-diol, Galectin-3, SODIUM ION, ... | Authors: | Kumar, A, Jinal, S, Raman, S, Ghosh, K. | Deposit date: | 2023-03-04 | Release date: | 2024-03-06 | Last modified: | 2024-09-18 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Identification of benzothiazole derived monosaccharides as potent, selective, and orally bioavailable inhibitors of human and mouse galectin-3; a rare example of using a S-O binding interaction for drug design Bioorg.Med.Chem., 101, 2024
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3U21
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2OOK
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2Q3L
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5F9W
| Crystal structure of broadly neutralizing VH1-46 germline-derived CD4-binding site-directed antibody CH235 in complex with HIV-1 clade A/E 93TH057 gp120 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of CH235-lineage antibody CH235, Light chain of CH235-lineage antibody CH235, ... | Authors: | Chen, L, Zhou, T, Kwong, P.D. | Deposit date: | 2015-12-10 | Release date: | 2016-03-09 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.8911 Å) | Cite: | Maturation Pathway from Germline to Broad HIV-1 Neutralizer of a CD4-Mimic Antibody. Cell, 165, 2016
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