5GUY
 
 | | Structural and functional study of chuY from E. coli CFT073 strain | | Descriptor: | Uncharacterized protein chuY | | Authors: | Kim, H, Choi, J, HA, S.C, Chaurasia, A.K, Kim, D, Kim, K.K. | | Deposit date: | 2016-08-31 | | Release date: | 2017-03-08 | | Method: | X-RAY DIFFRACTION (2.399 Å) | | Cite: | Structural and functional study of ChuY from Escherichia coli strain CFT073
Biochem. Biophys. Res. Commun., 482, 2017
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6IOZ
 | | Structural insights of idursulfase beta | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Kim, H, Kim, D, Hong, J, Lee, K, Seo, J, Oh, B.H. | | Deposit date: | 2018-11-01 | | Release date: | 2018-11-28 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Structural insights of idursulfase beta
To Be Published
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5WY8
 | | Crystal structure of PTP delta Ig1-Ig3 in complex with IL1RAPL1 Ig1-Ig3 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-1 receptor accessory protein-like 1, ... | | Authors: | Kim, H.M, Won, S.Y, Kim, D. | | Deposit date: | 2017-01-11 | | Release date: | 2017-11-22 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (3.07 Å) | | Cite: | LAR-RPTP Clustering Is Modulated by Competitive Binding between Synaptic Adhesion Partners and Heparan Sulfate
Front Mol Neurosci, 10, 2017
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5J6X
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4RCA
 | | Crystal structure of human PTPdelta and human Slitrk1 complex | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Receptor-type tyrosine-protein phosphatase delta, SLIT and NTRK-like protein 1, ... | | Authors: | Kim, H.M, Park, B.S, Kim, D, Lee, S.G. | | Deposit date: | 2014-09-15 | | Release date: | 2014-11-19 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.9908 Å) | | Cite: | Structural basis for LAR-RPTP/Slitrk complex-mediated synaptic adhesion.
Nat Commun, 5, 2014
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4RCW
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2Q9T
 | | High-resolution structure of the DING protein from Pseudomonas fluorescens | | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, DING, ... | | Authors: | Moniot, S, Ahn, S, Elias, M, Kim, D, Scott, K, Chabriere, E. | | Deposit date: | 2007-06-14 | | Release date: | 2008-06-17 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.43 Å) | | Cite: | Structure-function relationships in a bacterial DING protein.
Febs Lett., 581, 2007
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4QR0
 | | Crystal structure of Streptococcus pyogenes Cas2 at pH 5.6 | | Descriptor: | CRISPR-associated endoribonuclease Cas2 | | Authors: | Bae, E, Ka, D, Kim, D. | | Deposit date: | 2014-06-30 | | Release date: | 2014-11-26 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structural and functional characterization of Streptococcus pyogenes Cas2 protein under different pH conditions
Biochem.Biophys.Res.Commun., 451, 2014
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4QR1
 | | Crystal structure of Streptococcus pyogenes Cas2 at pH 6.5 | | Descriptor: | CRISPR-associated endoribonuclease Cas2 | | Authors: | Bae, E, Ka, D, Kim, D. | | Deposit date: | 2014-06-30 | | Release date: | 2014-11-26 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.193 Å) | | Cite: | Structural and functional characterization of Streptococcus pyogenes Cas2 protein under different pH conditions
Biochem.Biophys.Res.Commun., 451, 2014
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4QR2
 | | Crystal structure of Streptococcus pyogenes Cas2 at pH 7.5 | | Descriptor: | CRISPR-associated endoribonuclease Cas2 | | Authors: | Bae, E, Ka, D, Kim, D. | | Deposit date: | 2014-06-30 | | Release date: | 2014-11-26 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structural and functional characterization of Streptococcus pyogenes Cas2 protein under different pH conditions
Biochem.Biophys.Res.Commun., 451, 2014
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7YQ8
 | | Cryo-EM structure of human topoisomerase II beta in complex with DNA and etoposide | | Descriptor: | (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol -5-yl 4,6-O-[(1R)-ethylidene]-beta-D-glucopyranoside, 50-mer DNA, DNA topoisomerase 2-beta, ... | | Authors: | Naganuma, M, Ehara, H, Kim, D, Nakagawa, R, Cong, A, Bu, H, Jeong, J, Jang, J, Schellenberg, M.J, Bunch, H, Sekine, S. | | Deposit date: | 2022-08-05 | | Release date: | 2024-01-03 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | ERK2-topoisomerase II regulatory axis is important for gene activation in immediate early genes.
Nat Commun, 14, 2023
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8AZZ
 | | KRAS-G12V in complex with BI-2865 | | Descriptor: | (4S)-2-azanyl-4-methyl-4-[3-[4-[(1S)-1-[(2S)-1-methylpyrrolidin-1-ium-2-yl]ethoxy]pyrimidin-2-yl]-1,2,4-oxadiazol-5-yl]-6,7-dihydro-5H-1-benzothiophene-3-carbonitrile, 1,2-ETHANEDIOL, GTPase KRas, ... | | Authors: | Boettcher, J, Herdeis, L. | | Deposit date: | 2022-09-06 | | Release date: | 2023-06-21 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.02 Å) | | Cite: | Pan-KRAS inhibitor disables oncogenic signalling and tumour growth.
Nature, 619, 2023
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8AZR
 | | KRAS in complex with precursor 1 | | Descriptor: | (4~{S})-2-azanyl-4-[3-[6-[(2~{S})-2,4-dimethylpiperazin-1-yl]pyridin-2-yl]-1,2,4-oxadiazol-5-yl]-4-methyl-6,7-dihydro-5~{H}-1-benzothiophene-3-carbonitrile, 1,2-ETHANEDIOL, GTPase KRas, ... | | Authors: | Boettcher, J, Herdeis, L. | | Deposit date: | 2022-09-06 | | Release date: | 2023-06-07 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Pan-KRAS inhibitor disables oncogenic signalling and tumour growth.
Nature, 619, 2023
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8AZV
 | | KRAS in complex with BI-2865 | | Descriptor: | (4S)-2-azanyl-4-methyl-4-[3-[4-[(1S)-1-[(2S)-1-methylpyrrolidin-1-ium-2-yl]ethoxy]pyrimidin-2-yl]-1,2,4-oxadiazol-5-yl]-6,7-dihydro-5H-1-benzothiophene-3-carbonitrile, 1,2-ETHANEDIOL, GTPase KRas, ... | | Authors: | Boettcher, J, Herdeis, L. | | Deposit date: | 2022-09-06 | | Release date: | 2023-06-07 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.05 Å) | | Cite: | Pan-KRAS inhibitor disables oncogenic signalling and tumour growth.
Nature, 619, 2023
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8B00
 | | KRAS-G13D in complex with BI-2865 | | Descriptor: | (4S)-2-azanyl-4-methyl-4-[3-[4-[(1S)-1-[(2S)-1-methylpyrrolidin-1-ium-2-yl]ethoxy]pyrimidin-2-yl]-1,2,4-oxadiazol-5-yl]-6,7-dihydro-5H-1-benzothiophene-3-carbonitrile, 1,2-ETHANEDIOL, GTPase KRas, ... | | Authors: | Boettcher, J, Herdeis, L. | | Deposit date: | 2022-09-06 | | Release date: | 2023-06-07 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.04 Å) | | Cite: | Pan-KRAS inhibitor disables oncogenic signalling and tumour growth.
Nature, 619, 2023
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8AZY
 | | KRAS-G12D in complex with BI-2865 | | Descriptor: | (4S)-2-azanyl-4-methyl-4-[3-[4-[(1S)-1-[(2S)-1-methylpyrrolidin-1-ium-2-yl]ethoxy]pyrimidin-2-yl]-1,2,4-oxadiazol-5-yl]-6,7-dihydro-5H-1-benzothiophene-3-carbonitrile, 1,2-ETHANEDIOL, GTPase KRas, ... | | Authors: | Boettcher, J, Herdeis, L. | | Deposit date: | 2022-09-06 | | Release date: | 2023-06-07 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.09 Å) | | Cite: | Pan-KRAS inhibitor disables oncogenic signalling and tumour growth.
Nature, 619, 2023
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8AZX
 | | KRAS-G12C in complex with BI-2865 | | Descriptor: | (4S)-2-azanyl-4-methyl-4-[3-[4-[(1S)-1-[(2S)-1-methylpyrrolidin-1-ium-2-yl]ethoxy]pyrimidin-2-yl]-1,2,4-oxadiazol-5-yl]-6,7-dihydro-5H-1-benzothiophene-3-carbonitrile, 1,2-ETHANEDIOL, GTPase KRas, ... | | Authors: | Boettcher, J, Herdeis, L. | | Deposit date: | 2022-09-06 | | Release date: | 2023-06-07 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.04 Å) | | Cite: | Pan-KRAS inhibitor disables oncogenic signalling and tumour growth.
Nature, 619, 2023
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8ONV
 | | KRAS-G13D in complex with BI-2493 | | Descriptor: | (7~{S})-2'-azanyl-3-[2-[(2~{S})-2-methylpiperazin-1-yl]pyrimidin-4-yl]spiro[5,6-dihydro-4~{H}-1,2-benzoxazole-7,4'-6,7-dihydro-5~{H}-1-benzothiophene]-3'-carbonitrile, 1,2-ETHANEDIOL, GTPase KRas, ... | | Authors: | Boettcher, J, Herdeis, L. | | Deposit date: | 2023-04-04 | | Release date: | 2023-06-07 | | Last modified: | 2023-07-19 | | Method: | X-RAY DIFFRACTION (1.01 Å) | | Cite: | Pan-KRAS inhibitor disables oncogenic signalling and tumour growth.
Nature, 619, 2023
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3ZHK
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3ZHD
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3ZHL
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2N8N
 | | Solution structure of translation initiation factor | | Descriptor: | Translation initiation factor IF-1 | | Authors: | Kim, D, Lee, K, Lee, B. | | Deposit date: | 2015-10-21 | | Release date: | 2016-10-26 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Structure and dynamics study of translation initiation factor 1 from Staphylococcus aureus suggests its RNA binding mode
Biochim.Biophys.Acta, 1865, 2017
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3IQY
 | | Active site mutants of B. subtilis SecA | | Descriptor: | Protein translocase subunit secA, SULFATE ION | | Authors: | Kim, D, Hunt, J.F. | | Deposit date: | 2009-08-21 | | Release date: | 2010-08-11 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | ATPase Active-Site Electrostatic Interactions Control the Global Conformation of the 100 kDa SecA Translocase.
J.Am.Chem.Soc., 135, 2013
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3IQM
 | | Active site mutants of B. subtilis SecA | | Descriptor: | Protein translocase subunit secA, SULFATE ION | | Authors: | Kim, D, Hunt, J.F. | | Deposit date: | 2009-08-20 | | Release date: | 2010-08-11 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (3.4 Å) | | Cite: | ATPase Active-Site Electrostatic Interactions Control the Global Conformation of the 100 kDa SecA Translocase.
J.Am.Chem.Soc., 135, 2013
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6P5G
 | | Photoactive Yellow Protein PYP Dark Full | | Descriptor: | Photoactive yellow protein | | Authors: | Pandey, S, Schmidt, M. | | Deposit date: | 2019-05-30 | | Release date: | 2019-09-18 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Time-resolved serial femtosecond crystallography at the European XFEL.
Nat.Methods, 17, 2020
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