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7XUG
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BU of 7xug by Molmil
cryo-EM structure of HK022 putRNA-less E.coli RNA polymerase elongation complex
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Hwang, S, Kang, J.Y.
Deposit date:2022-05-18
Release date:2022-08-10
Last modified:2022-08-31
Method:ELECTRON MICROSCOPY (3.57 Å)
Cite:Structural basis of transcriptional regulation by a nascent RNA element, HK022 putRNA.
Nat Commun, 13, 2022
7XUI
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BU of 7xui by Molmil
Cryo-EM structure of sigma70 bound HK022 putRNA-associated E.coli RNA polymerase elongation complex
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Hwang, S, Kang, J.Y.
Deposit date:2022-05-18
Release date:2022-08-10
Last modified:2022-08-31
Method:ELECTRON MICROSCOPY (3.61 Å)
Cite:Structural basis of transcriptional regulation by a nascent RNA element, HK022 putRNA.
Nat Commun, 13, 2022
2L0O
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BU of 2l0o by Molmil
DsbB3 peptide structure in 100% TFE
Descriptor: Oxidoreductase that catalyzes reoxidation of DsbA protein disulfide isomerase I
Authors:Hwang, S, Hilty, C.
Deposit date:2010-07-08
Release date:2011-03-09
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Folding determinants of disulfide bond forming protein B explored by solution nuclear magnetic resonance spectroscopy.
Proteins, 79, 2011
2L0M
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BU of 2l0m by Molmil
DsbB2 peptide structure in 100% TFE
Descriptor: Oxidoreductase that catalyzes reoxidation of DsbA protein disulfide isomerase I
Authors:Hwang, S, Hilty, C.
Deposit date:2010-07-08
Release date:2011-03-09
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Folding determinants of disulfide bond forming protein B explored by solution nuclear magnetic resonance spectroscopy.
Proteins, 79, 2011
2L0N
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BU of 2l0n by Molmil
DsbB3 peptide structure in 70% TFE
Descriptor: Oxidoreductase that catalyzes reoxidation of DsbA protein disulfide isomerase I
Authors:Hwang, S, Hilty, C.
Deposit date:2010-07-08
Release date:2011-03-09
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Folding determinants of disulfide bond forming protein B explored by solution nuclear magnetic resonance spectroscopy.
Proteins, 79, 2011
2L0L
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BU of 2l0l by Molmil
DsbB2 peptide structure in 70% TFE
Descriptor: Oxidoreductase that catalyzes reoxidation of DsbA protein disulfide isomerase I
Authors:Hwang, S, Hilty, C.
Deposit date:2010-07-08
Release date:2011-03-09
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Folding determinants of disulfide bond forming protein B explored by solution nuclear magnetic resonance spectroscopy.
Proteins, 79, 2011
6E08
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BU of 6e08 by Molmil
Crystal structure of G6PD in complex with structural NADP
Descriptor: GLYCEROL, Glucose-6-phosphate 1-dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Rahighi, S, Mochly Rosen, D, Wakatsuki, S.
Deposit date:2018-07-06
Release date:2018-07-25
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Correcting glucose-6-phosphate dehydrogenase deficiency with a small-molecule activator.
Nat Commun, 9, 2018
6E07
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BU of 6e07 by Molmil
Crystal structure of Canton G6PD in complex with structural NADP
Descriptor: GLYCEROL, Glucose-6-phosphate 1-dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Rahighi, S, Mochly-Rosen, D, Wakatsuki, S.
Deposit date:2018-07-06
Release date:2018-07-25
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Correcting glucose-6-phosphate dehydrogenase deficiency with a small-molecule activator.
Nat Commun, 9, 2018
7MSL
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BU of 7msl by Molmil
Structure of anti-CRISPR AcrIIC4 from Haemophilus parainfluenzae
Descriptor: AcrIIC4, IODIDE ION
Authors:Pan, C, Maxwell, K.L, Moraes, T.F.
Deposit date:2021-05-11
Release date:2022-03-23
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Structural and Mechanistic Insight into CRISPR-Cas9 Inhibition by Anti-CRISPR Protein AcrIIC4 Hpa.
J.Mol.Biol., 434, 2022
7XUE
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BU of 7xue by Molmil
Cryo-EM structure of HK022 putRNA-associated E.coli RNA polymerase elongation complex
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Hwang, S.H, Kang, J.Y.
Deposit date:2022-05-18
Release date:2022-08-10
Last modified:2022-08-31
Method:ELECTRON MICROSCOPY (3.17 Å)
Cite:Structural basis of transcriptional regulation by a nascent RNA element, HK022 putRNA.
Nat Commun, 13, 2022
8F3K
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BU of 8f3k by Molmil
Anti-CRISPR protein AcrIIC5 inhibits CRISPR-Cas9 by acting as a DNA mimic
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACRIIC5Nch, AMMONIUM ION, ...
Authors:Shah, M, Sungwon, H, Davidson, A.R, Maxwell, K.L, Moraes, T.F.
Deposit date:2022-11-10
Release date:2023-03-08
Last modified:2023-04-12
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Anti-CRISPR Protein AcrIIC5 Inhibits CRISPR-Cas9 by Occupying the Target DNA Binding Pocket.
J.Mol.Biol., 435, 2023
6XVF
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BU of 6xvf by Molmil
Crystal structure of bovine cytochrome bc1 in complex with tetrahydro-quinolone inhibitor JAG021
Descriptor: 1,2-DIHEXANOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, ...
Authors:Amporndanai, K, Hasnain, S.S, Antonyuk, S.V.
Deposit date:2020-01-21
Release date:2020-07-22
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Potent Tetrahydroquinolone Eliminates Apicomplexan Parasites.
Front Cell Infect Microbiol, 10, 2020
7NAM
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BU of 7nam by Molmil
LRP6_E1 in complex with Lr-EET-3.5
Descriptor: Low-density lipoprotein receptor-related protein 6, SODIUM ION, Trypsin inhibitor 2, ...
Authors:Hansen, S, Hannoush, R.N.
Deposit date:2021-06-21
Release date:2022-06-29
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Directed evolution identifies high-affinity cystine-knot peptide agonists and antagonists of Wnt/ beta-catenin signaling.
Proc.Natl.Acad.Sci.USA, 119, 2022
8CTG
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BU of 8ctg by Molmil
Extracellular architecture of an engineered canonical Wnt signaling ternary complex
Descriptor: Frizzled-8, Low-density lipoprotein receptor-related protein 6, PALMITOLEIC ACID, ...
Authors:Tsutsumi, N, Jude, K.M, Garcia, K.C.
Deposit date:2022-05-14
Release date:2023-03-15
Last modified:2023-03-22
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structure of the Wnt-Frizzled-LRP6 initiation complex reveals the basis for coreceptor discrimination.
Proc.Natl.Acad.Sci.USA, 120, 2023
8DVM
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BU of 8dvm by Molmil
Crystal structure of LRP6 E3E4 in complex with disulfide constrained peptide E3.6
Descriptor: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Thakur, A.K, Liau, N.P.D, Sudhamsu, J, Hannoush, R.N.
Deposit date:2022-07-29
Release date:2023-03-29
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2 Å)
Cite:Synthetic Multivalent Disulfide-Constrained Peptide Agonists Potentiate Wnt1/ beta-Catenin Signaling via LRP6 Coreceptor Clustering.
Acs Chem.Biol., 18, 2023
8DVL
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BU of 8dvl by Molmil
Crystal structure of LRP6 E3E4 in complex with disulfide constrained peptide E3.18
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Thakur, A.K, Liau, N.P.D, Sudhamsu, J, Hannoush, R.N.
Deposit date:2022-07-29
Release date:2023-03-29
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Synthetic Multivalent Disulfide-Constrained Peptide Agonists Potentiate Wnt1/ beta-Catenin Signaling via LRP6 Coreceptor Clustering.
Acs Chem.Biol., 18, 2023
8DVN
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BU of 8dvn by Molmil
Crystal structure of LRP6 E3E4 in complex with disulfide constrained peptide E3.10
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Thakur, A.K, Liau, N.P.D, Sudhamsu, J, Hannoush, R.N.
Deposit date:2022-07-29
Release date:2023-03-29
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.53 Å)
Cite:Synthetic Multivalent Disulfide-Constrained Peptide Agonists Potentiate Wnt1/ beta-Catenin Signaling via LRP6 Coreceptor Clustering.
Acs Chem.Biol., 18, 2023
6VA7
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BU of 6va7 by Molmil
Crystal structure of glucose-6-phosphate dehydrogenase P396L mutant in complex with catalytic NADP+
Descriptor: Glucose-6-phosphate 1-dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Horikoshi, N, Mochly-Rosen, D, Wakatsuki, S.
Deposit date:2019-12-17
Release date:2021-01-27
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.07 Å)
Cite:Long-range structural defects by pathogenic mutations in most severe glucose-6-phosphate dehydrogenase deficiency.
Proc.Natl.Acad.Sci.USA, 118, 2021
6VA8
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BU of 6va8 by Molmil
Crystal structure of glucose-6-phosphate dehydrogenase F381L mutant in complex with catalytic NADP+
Descriptor: Glucose-6-phosphate 1-dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Horikoshi, N, Mochly-Rosen, D, Wakatsuki, S.
Deposit date:2019-12-17
Release date:2021-01-27
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.95 Å)
Cite:Long-range structural defects by pathogenic mutations in most severe glucose-6-phosphate dehydrogenase deficiency.
Proc.Natl.Acad.Sci.USA, 118, 2021
6VA9
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BU of 6va9 by Molmil
Crystal structure of glucose-6-phosphate dehydrogenase R393H mutant in complex with catalytic NADP+
Descriptor: Glucose-6-phosphate 1-dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Horikoshi, N, Mochly-Rosen, D, Wakatsuki, S.
Deposit date:2019-12-17
Release date:2021-01-27
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.95 Å)
Cite:Long-range structural defects by pathogenic mutations in most severe glucose-6-phosphate dehydrogenase deficiency.
Proc.Natl.Acad.Sci.USA, 118, 2021
6VAQ
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BU of 6vaq by Molmil
Crystal structure of glucose-6-phosphate dehydrogenase V394L mutant in complex with catalytic NADP+
Descriptor: Glucose-6-phosphate 1-dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Horikoshi, N, Mochly-Rosen, D, Wakatsuki, S.
Deposit date:2019-12-17
Release date:2021-01-27
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Long-range structural defects by pathogenic mutations in most severe glucose-6-phosphate dehydrogenase deficiency.
Proc.Natl.Acad.Sci.USA, 118, 2021
6VA0
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BU of 6va0 by Molmil
Crystal structure of glucose-6-phosphate dehydrogenase W509A mutant in complex with catalytic NADP+
Descriptor: Glucose-6-phosphate 1-dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Horikoshi, N, Mochly-Rosen, D, Wakatsuki, S.
Deposit date:2019-12-16
Release date:2021-01-27
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Long-range structural defects by pathogenic mutations in most severe glucose-6-phosphate dehydrogenase deficiency.
Proc.Natl.Acad.Sci.USA, 118, 2021
8FFE
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BU of 8ffe by Molmil
Crystal structure of LRP6 E1E2 domains bound to YW210.09 Fab and engineered XWnt8 peptide
Descriptor: GLYCEROL, Low-density lipoprotein receptor-related protein 6, SODIUM ION, ...
Authors:Jude, K.M, Tsutsumi, N, Waghray, D, Garcia, K.C.
Deposit date:2022-12-08
Release date:2023-03-08
Last modified:2023-03-22
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Structure of the Wnt-Frizzled-LRP6 initiation complex reveals the basis for coreceptor discrimination.
Proc.Natl.Acad.Sci.USA, 120, 2023
2N7H
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BU of 2n7h by Molmil
Hybrid structure of the Type 1 Pilus of Uropathogenic E.coli
Descriptor: FimA
Authors:Habenstein, B, Loquet, A, Giller, K, Vasa, S, Becker, S, Habeck, M, Lange, A.
Deposit date:2015-09-11
Release date:2015-09-23
Last modified:2015-10-14
Method:SOLID-STATE NMR
Cite:Hybrid Structure of the Type 1 Pilus of Uropathogenic Escherichia coli.
Angew.Chem.Int.Ed.Engl., 54, 2015
8G4Y
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BU of 8g4y by Molmil
Structure of ZNRF3 ECD bound to peptide MK1-3.6.10
Descriptor: E3 ubiquitin-protein ligase ZNRF3, MK1-3.6.10
Authors:Harris, S.F, Wu, P.
Deposit date:2023-02-10
Release date:2023-12-20
Method:X-RAY DIFFRACTION (1.41 Å)
Cite:Potent and selective binders of the E3 ubiquitin ligase ZNRF3 stimulate Wnt signaling and intestinal organoid growth.
Cell Chem Biol, 2023

 

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