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7CV9
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BU of 7cv9 by Molmil
RNA methyltransferase METTL4
Descriptor: GLYCEROL, Methyltransferase-like protein 2, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Luo, Q, Ma, J.
Deposit date:2020-08-25
Release date:2021-09-01
Last modified:2022-10-12
Method:X-RAY DIFFRACTION (2.455 Å)
Cite:Structural insights into molecular mechanism for N6-adenosine methylation by MT-A70 family methyltransferase METTL4
Nat Commun, 13, 2022
7CV7
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BU of 7cv7 by Molmil
RNA methyltransferase METTL4
Descriptor: Methyltransferase-like protein 2, S-ADENOSYLMETHIONINE
Authors:Luo, Q, Ma, J.
Deposit date:2020-08-25
Release date:2021-09-01
Last modified:2022-10-12
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural insights into molecular mechanism for N6-adenosine methylation by MT-A70 family methyltransferase METTL4
Nat Commun, 13, 2022
5J87
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BU of 5j87 by Molmil
Discovery of N-(3-(5-((3-acrylamido-4-(morpholine-4-carbonyl)phenyl)amino)-1-methyl-6-oxo-1,6-dihydropyridin-3-yl)-2-methylphenyl)-4-(tert-butyl)benzamide (CHMFL-BTK-01) as a Highly Selective Irreversible BTK Kinase Inhibitor
Descriptor: N-[3-(5-{[3-(acryloylamino)-4-(morpholine-4-carbonyl)phenyl]amino}-1-methyl-6-oxo-1,6-dihydropyridin-3-yl)-2-methylphenyl]-4-tert-butylbenzamide, Tyrosine-protein kinase BTK
Authors:Yun, C.H, Zhang, S.
Deposit date:2016-04-07
Release date:2017-04-19
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:Discovery of N-(3-(5-((3-acrylamido-4-(morpholine-4-carbonyl)phenyl)amino)-1-methyl-6-oxo-1,6-dihydropyridin-3-yl)-2-methylphenyl)-4-(tert-butyl)benzamide (CHMFL-BTK-01) as a highly selective irreversible Bruton's tyrosine kinase (BTK) inhibitor.
Eur J Med Chem, 131, 2017
6J99
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BU of 6j99 by Molmil
Cryo-EM structure of human DOT1L in complex with an H2B-monoubiquitinated nucleosome
Descriptor: DNA (144-MER), DNA (145-MER), Histone H2A, ...
Authors:Yao, T, Huang, J.
Deposit date:2019-01-22
Release date:2019-02-27
Last modified:2019-04-10
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structural basis of the crosstalk between histone H2B monoubiquitination and H3 lysine 79 methylation on nucleosome.
Cell Res., 29, 2019
5YUD
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BU of 5yud by Molmil
Flagellin derivative in complex with the NLR protein NAIP5
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Baculoviral IAP repeat-containing protein 1e, Phase 2 flagellin,Flagellin
Authors:Yang, X.R, Yang, F, Wang, W.G, Lin, G.Z.
Deposit date:2017-11-21
Release date:2018-01-03
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (4.28 Å)
Cite:Structural basis for specific flagellin recognition by the NLR protein NAIP5.
Cell Res., 28, 2018
1P9Z
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BU of 1p9z by Molmil
The Solution Structure of Antifungal Peptide Distinct With a Five-disulfide Motif from Eucommia ulmoides Oliver
Descriptor: Eucommia Antifungal peptide 2
Authors:Huang, R.H, Xiang, Y, Tu, G.Z, Zhang, Y, Wang, D.C.
Deposit date:2003-05-13
Release date:2004-05-25
Last modified:2019-12-25
Method:SOLUTION NMR
Cite:Solution Structure of Eucommia Antifungal Peptide: A Novel Structural Model Distinct with a Five-Disulfide Motif.
Biochemistry, 43, 2004
8HM0
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BU of 8hm0 by Molmil
F8-A22-E4 complex of MPXV in trimeric form
Descriptor: DNA polymerase, DNA polymerase processivity factor component A20, E4R
Authors:Li, Y.N, Shen, Y.P, Hu, Z.W, Yan, R.H.
Deposit date:2022-12-02
Release date:2023-05-31
Last modified:2023-12-13
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural basis for the assembly of the DNA polymerase holoenzyme from a monkeypox virus variant.
Sci Adv, 9, 2023
8HLZ
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BU of 8hlz by Molmil
F8-A22-E4 complex of MPXV in hexameric form
Descriptor: DNA polymerase, DNA polymerase processivity factor component A20, E4R
Authors:Li, Y.N, Shen, Y.P, Hu, Z.W, Yan, R.H.
Deposit date:2022-12-02
Release date:2023-05-31
Last modified:2023-12-13
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural basis for the assembly of the DNA polymerase holoenzyme from a monkeypox virus variant.
Sci Adv, 9, 2023
8K8H
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BU of 8k8h by Molmil
Crystal structure of the CysR-CTLD3 fragment of human DEC205
Descriptor: Lymphocyte antigen 75
Authors:Qian, Y, Kong, D, Yu, B, He, Y.
Deposit date:2023-07-29
Release date:2024-02-28
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:Interaction of human dendritic cell receptor DEC205/CD205 with keratins.
J.Biol.Chem., 300, 2024
7X77
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BU of 7x77 by Molmil
Ectodomain structure of per os infectivity factor 5
Descriptor: Per os infectivity factor 5
Authors:Cao, S, Li, Z, Fu, Y.
Deposit date:2022-03-09
Release date:2022-06-22
Last modified:2022-08-10
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Characterization of Per Os Infectivity Factor 5 (PIF5) Reveals the Essential Role of Intramolecular Interactions in Baculoviral Oral Infectivity.
J.Virol., 96, 2022
1YGY
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BU of 1ygy by Molmil
Crystal Structure of D-3-Phosphoglycerate dehydrogenase From Mycobacterium tuberculosis
Descriptor: D-3-phosphoglycerate dehydrogenase, L(+)-TARTARIC ACID
Authors:Dey, S, Grant, G.A, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC)
Deposit date:2005-01-05
Release date:2005-01-25
Last modified:2019-07-10
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structure of Mycobacterium tuberculosis D-3-Phosphoglycerate Dehydrogenase: EXTREME ASYMMETRY IN A TETRAMER OF IDENTICAL SUBUNITS
J.Biol.Chem., 280, 2005
7XPQ
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BU of 7xpq by Molmil
Crystal Structure of UDP-Glc/GlcNAc 4-Epimerase with NAD/UDP-GlcNAc
Descriptor: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, UDP-glucose 4-epimerase, URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE
Authors:Chen, Y.H, Wang, X.C, Zhang, C.R.
Deposit date:2022-05-05
Release date:2023-05-17
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:A maize epimerase modulates cell wall synthesis and glycosylation during stomatal morphogenesis.
Nat Commun, 14, 2023
7XPO
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BU of 7xpo by Molmil
Crystal Structure of UDP-Glc/GlcNAc 4-Epimerase with NAD/UDP-Glc
Descriptor: GLYCEROL, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, UDP-glucose 4-epimerase, ...
Authors:Chen, Y.H, Wang, X.C, Zhang, C.R.
Deposit date:2022-05-05
Release date:2023-05-17
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:A maize epimerase modulates cell wall synthesis and glycosylation during stomatal morphogenesis.
Nat Commun, 14, 2023
7XPP
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BU of 7xpp by Molmil
Crystal Structure of UDP-Glc/GlcNAc 4-Epimerase with NAD
Descriptor: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, UDP-glucose 4-epimerase
Authors:Chen, Y.H, Wang, X.C, Zhang, C.R.
Deposit date:2022-05-05
Release date:2023-05-24
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A maize epimerase modulates cell wall synthesis and glycosylation during stomatal morphogenesis.
Nat Commun, 14, 2023
7YNY
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BU of 7yny by Molmil
Crystal structure of baculovirus LEF-3 from Helicoverpa armigera nucleopolyhedrovirus
Descriptor: Lef3
Authors:Yin, J, Li, Z, Cao, S.
Deposit date:2022-08-01
Release date:2023-01-25
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3.51 Å)
Cite:Structural transitions during the cooperative assembly of baculovirus single-stranded DNA-binding protein on ssDNA.
Nucleic Acids Res., 50, 2022
7YPO
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BU of 7ypo by Molmil
Cryo-EM structure of baculovirus LEF-3 in complex with ssDNA
Descriptor: DNA (28-MER), Lef3
Authors:Yin, J, Fu, Y, Rao, G, Li, Z, Cao, S.
Deposit date:2022-08-04
Release date:2023-01-25
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural transitions during the cooperative assembly of baculovirus single-stranded DNA-binding protein on ssDNA.
Nucleic Acids Res., 50, 2022
7YPQ
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BU of 7ypq by Molmil
Cryo-EM structure of one baculovirus LEF-3 molecule in complex with ssDNA
Descriptor: DNA (5'-D(P*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3'), Lef3
Authors:Fu, Y, Rao, G, Yin, J, Li, Z, Cao, S.
Deposit date:2022-08-04
Release date:2023-01-25
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural transitions during the cooperative assembly of baculovirus single-stranded DNA-binding protein on ssDNA.
Nucleic Acids Res., 50, 2022
7VS3
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BU of 7vs3 by Molmil
The crystal structure of rat calcium-dependent activator protein for secretion (CAPS) C2PH
Descriptor: Calcium-dependent secretion activator 1, SULFATE ION
Authors:Zhou, H, Wei, Z.Q, Zhang, L, Ren, Y.J, Ma, C.
Deposit date:2021-10-25
Release date:2023-02-15
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.595 Å)
Cite:The C 2 and PH domains of CAPS constitute an effective PI(4,5)P2-binding unit essential for Ca 2+ -regulated exocytosis.
Structure, 31, 2023
7WZ6
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BU of 7wz6 by Molmil
Crystal structure of MyoD-E47
Descriptor: Isoform E47 of Transcription factor E2-alpha, Myoblast determination protein 1
Authors:Zhong, J, Huang, Y, Ma, J.
Deposit date:2022-02-17
Release date:2022-06-22
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structural basis of the bHLH domains of MyoD-E47 heterodimer.
Biochem.Biophys.Res.Commun., 621, 2022
5WYX
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BU of 5wyx by Molmil
Crystal structure of human TLR8 in complex with CU-CPT8m
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 7-(3-methylphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide, ...
Authors:Tanji, H, Ohto, U, Shimizu, T.
Deposit date:2017-01-16
Release date:2017-12-13
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Small-molecule inhibition of TLR8 through stabilization of its resting state
Nat. Chem. Biol., 14, 2018
5ZHH
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BU of 5zhh by Molmil
Structure of Inositol monophosphatase from Anabaena (Nostoc) sp. PCC 7120
Descriptor: Inositol-1-monophosphatase
Authors:Zhang, S.R, Wang, F.K.
Deposit date:2018-03-13
Release date:2019-04-03
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Structure of Inositol monophosphatase from Anabaena (Nostoc) sp. PCC 7120
To Be Published
8JKD
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BU of 8jkd by Molmil
Cryo-EM structure of CCHFV envelope protein Gc trimer in complex with Gc13 Fab
Descriptor: Glycoprotein C
Authors:Chong, T, Cao, S.
Deposit date:2023-06-01
Release date:2024-01-24
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Neutralizing monoclonal antibodies against the Gc fusion loop region of Crimean-Congo hemorrhagic fever virus.
Plos Pathog., 20, 2024
8JLW
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BU of 8jlw by Molmil
CCHFV envelope protein Gc in complex with Gc8
Descriptor: Glycoprotein C,CCHFV envelope protein Gc fusion loops, Mouse antibody Gc8 heavy chain, Mouse antibody Gc8 light chain
Authors:Chong, T, Cao, S.
Deposit date:2023-06-03
Release date:2024-01-24
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Neutralizing monoclonal antibodies against the Gc fusion loop region of Crimean-Congo hemorrhagic fever virus.
Plos Pathog., 20, 2024
8JLX
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BU of 8jlx by Molmil
CCHFV envelope protein Gc in complex with Gc13
Descriptor: Glycoprotein C,CCHFV Gc fusion loops, Mouse antibody Gc13 heavy chain, Mouse antibody Gc13 light chain
Authors:Chong, T, Cao, S.
Deposit date:2023-06-03
Release date:2024-01-24
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Neutralizing monoclonal antibodies against the Gc fusion loop region of Crimean-Congo hemorrhagic fever virus.
Plos Pathog., 20, 2024
7XC6
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BU of 7xc6 by Molmil
Photobacterium phosphoreum fatty acid reductase complex LuxC-LuxE
Descriptor: Long-chain acyl-protein thioester reductase, LuxE
Authors:Tian, Q, Huo, Y, Wang, L.
Deposit date:2022-03-23
Release date:2022-04-20
Last modified:2022-08-10
Method:ELECTRON MICROSCOPY (2.79 Å)
Cite:Cryo-EM structure of the fatty acid reductase LuxC-LuxE complex provides insights into bacterial bioluminescence.
J.Biol.Chem., 298, 2022

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