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3DSX
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BU of 3dsx by Molmil
Crystal structure of RabGGTase(DELTA LRR; DELTA IG)in complex with di-prenylated peptide Ser-Cys(GG)-Ser-Cys(GG) derivated from Rab7
Descriptor: CALCIUM ION, GERAN-8-YL GERAN, Geranylgeranyl transferase type-2 subunit alpha, ...
Authors:Guo, Z, Yu, S, Goody, R.S, Alexandrov, K, Blankenfeldt, W.
Deposit date:2008-07-14
Release date:2008-09-09
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structures of RabGGTase-substrate/product complexes provide insights into the evolution of protein prenylation
Embo J., 27, 2008
3DSW
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BU of 3dsw by Molmil
Crystal structure of RabGGTase(DELTA LRR; DELTA IG)in complex with mono-prenylated peptide Ser-Cys(GG)-Ser-Cys derivated from Rab7
Descriptor: CALCIUM ION, GERAN-8-YL GERAN, Geranylgeranyl transferase type-2 subunit alpha, ...
Authors:Guo, Z, Yu, S, Goody, R.S, Alexandrov, K, Blankenfeldt, W.
Deposit date:2008-07-14
Release date:2008-09-09
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structures of RabGGTase-substrate/product complexes provide insights into the evolution of protein prenylation
Embo J., 27, 2008
3DST
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BU of 3dst by Molmil
Crystal structure of RabGGTase(DELTA LRR; DELTA IG)in complex with geranylgeranyl pyrophosphate
Descriptor: CALCIUM ION, GERANYLGERANYL DIPHOSPHATE, Geranylgeranyl transferase type-2 subunit alpha, ...
Authors:Guo, Z, Yu, S, Goody, R.S, Alexandrov, K, Blankenfeldt, W.
Deposit date:2008-07-14
Release date:2008-09-09
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structures of RabGGTase-substrate/product complexes provide insights into the evolution of protein prenylation
Embo J., 27, 2008
3DSV
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BU of 3dsv by Molmil
Crystal structure of RabGGTase(DELTA LRR; DELTA IG)in complex with mono-prenylated peptide Ser-Cys-Ser-Cys(GG) derivated from Rab7
Descriptor: CALCIUM ION, GERAN-8-YL GERAN, Geranylgeranyl transferase type-2 subunit alpha, ...
Authors:Guo, Z, Yu, S, Goody, R.S, Alexandrov, K, Blankenfeldt, W.
Deposit date:2008-07-14
Release date:2008-09-09
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structures of RabGGTase-substrate/product complexes provide insights into the evolution of protein prenylation
Embo J., 27, 2008
3DSU
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BU of 3dsu by Molmil
Crystal structure of RabGGTase(DELTA LRR; DELTA IG)in complex with farnesyl pyrophosphate
Descriptor: CALCIUM ION, FARNESYL DIPHOSPHATE, Geranylgeranyl transferase type-2 subunit alpha, ...
Authors:Guo, Z, Yu, S, Goody, R.S, Alexandrov, K, Blankenfeldt, W.
Deposit date:2008-07-14
Release date:2008-09-09
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structures of RabGGTase-substrate/product complexes provide insights into the evolution of protein prenylation
Embo J., 27, 2008
5P21
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BU of 5p21 by Molmil
REFINED CRYSTAL STRUCTURE OF THE TRIPHOSPHATE CONFORMATION OF H-RAS P21 AT 1.35 ANGSTROMS RESOLUTION: IMPLICATIONS FOR THE MECHANISM OF GTP HYDROLYSIS
Descriptor: C-H-RAS P21 PROTEIN, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
Authors:Pai, E.F, Wittinghofer, A, Kabsch, W.
Deposit date:1990-04-30
Release date:1992-01-15
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Refined crystal structure of the triphosphate conformation of H-ras p21 at 1.35 A resolution: implications for the mechanism of GTP hydrolysis.
EMBO J., 9, 1990
2TMK
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BU of 2tmk by Molmil
YEAST THYMIDYLATE KINASE COMPLEXED WITH 3'-AZIDO-3'-DEOXYTHYMIDINE MONOPHOSPHATE (AZT-MP)
Descriptor: 3'-AZIDO-3'-DEOXYTHYMIDINE-5'-MONOPHOSPHATE, SULFATE ION, THYMIDYLATE KINASE
Authors:Lavie, A, Schlichting, I.
Deposit date:1997-06-12
Release date:1998-06-17
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of thymidylate kinase reveals the cause behind the limiting step in AZT activation.
Nat.Struct.Biol., 4, 1997
7OK3
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BU of 7ok3 by Molmil
Crystal Structure of KRasG13C in Complex with Nucleotide-based Covalent Inhibitor edaGDP
Descriptor: Isoform 2B of GTPase KRas, edaGDP
Authors:Goebel, L, Mueller, M.P, Rauh, D.
Deposit date:2021-05-17
Release date:2022-08-03
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Targeting oncogenic KRasG13C with nucleotide-based covalent inhibitors.
Elife, 12, 2023
7OK4
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BU of 7ok4 by Molmil
Crystal Structure of KRasG13C in Complex with Nucleotide-based covalent Inhibitor bdaGDP
Descriptor: Isoform 2B of GTPase KRas, bdaGDP
Authors:Goebel, L, Mueller, M.P, Rauh, D.
Deposit date:2021-05-17
Release date:2022-08-03
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Targeting oncogenic KRasG13C with nucleotide-based covalent inhibitors.
Elife, 12, 2023
1TMK
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BU of 1tmk by Molmil
YEAST THYMIDYLATE KINASE COMPLEXED WITH THYMIDINE MONOPHOSPHATE (DTMP)
Descriptor: SULFATE ION, THYMIDINE-5'-PHOSPHATE, THYMIDYLATE KINASE
Authors:Lavie, A, Schlichting, I.
Deposit date:1997-06-12
Release date:1998-06-17
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of thymidylate kinase reveals the cause behind the limiting step in AZT activation.
Nat.Struct.Biol., 4, 1997
1EK0
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BU of 1ek0 by Molmil
GPPNHP-BOUND YPT51 AT 1.48 A RESOLUTION
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, NICKEL (II) ION, ...
Authors:Esters, H, Scheidig, A.J.
Deposit date:2000-03-06
Release date:2000-04-17
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:High-resolution crystal structure of S. cerevisiae Ypt51(DeltaC15)-GppNHp, a small GTP-binding protein involved in regulation of endocytosis.
J.Mol.Biol., 298, 2000
4UKD
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BU of 4ukd by Molmil
UMP/CMP KINASE FROM SLIME MOLD COMPLEXED WITH ADP, UDP, BERYLLIUM FLUORIDE
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM DIFLUORIDE, MAGNESIUM ION, ...
Authors:Schlichting, I, Reinstein, J.
Deposit date:1997-05-20
Release date:1998-05-20
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structures of active conformations of UMP kinase from Dictyostelium discoideum suggest phosphoryl transfer is associative.
Biochemistry, 36, 1997
2BCG
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BU of 2bcg by Molmil
Structure of doubly prenylated Ypt1:GDI complex
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GERAN-8-YL GERAN, GTP-binding protein YPT1, ...
Authors:Pylypenko, O, Rak, A, Alexandrov, K.
Deposit date:2005-10-19
Release date:2006-01-17
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Structure of doubly prenylated Ypt1:GDI complex and the mechanism of GDI-mediated Rab recycling
Embo J., 25, 2006
1WQ1
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BU of 1wq1 by Molmil
RAS-RASGAP COMPLEX
Descriptor: ALUMINUM FLUORIDE, GUANOSINE-5'-DIPHOSPHATE, H-RAS, ...
Authors:Scheffzek, K, Ahmadian, M.R, Kabsch, W, Wiesmueller, L, Lautwein, A, Schmitz, F, Wittinghofer, A.
Deposit date:1997-07-03
Release date:1998-07-15
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The Ras-RasGAP complex: structural basis for GTPase activation and its loss in oncogenic Ras mutants.
Science, 277, 1997
2EVW
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BU of 2evw by Molmil
Crystal structure analysis of a fluorescent form of H-Ras p21 in complex with R-caged GTP
Descriptor: GTPase HRas, GUANOSINE 5'-TRIPHOSPHATE P3-[1-(2-NITROPHENYL)ETHYL ESTER], MAGNESIUM ION, ...
Authors:Klink, B.U.
Deposit date:2005-11-01
Release date:2006-05-30
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.05 Å)
Cite:A newly designed microspectrofluorometer for kinetic studies on protein crystals in combination with x-ray diffraction.
Biophys.J., 91, 2006
4TMK
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BU of 4tmk by Molmil
COMPLEX OF E. COLI THYMIDYLATE KINASE WITH THE BISUBSTRATE INHIBITOR TP5A
Descriptor: P1-(5'-ADENOSYL)P5-(5'-THYMIDYL)PENTAPHOSPHATE, PROTEIN (THYMIDYLATE KINASE)
Authors:Lavie, A, Ostermann, N, Schlichting, I.
Deposit date:1998-08-31
Release date:1998-11-25
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Structural basis for efficient phosphorylation of 3'-azidothymidine monophosphate by Escherichia coli thymidylate kinase.
Proc.Natl.Acad.Sci.USA, 95, 1998
1KY2
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BU of 1ky2 by Molmil
GPPNHP-BOUND YPT7P AT 1.6 A RESOLUTION
Descriptor: GTP-BINDING PROTEIN YPT7P, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
Authors:Constantinescu, A.-T, Rak, A, Scheidig, A.J.
Deposit date:2002-02-02
Release date:2002-06-05
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Rab-subfamily-specific regions of Ypt7p are structurally different from other RabGTPases.
Structure, 10, 2002
1KY3
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BU of 1ky3 by Molmil
GDP-BOUND YPT7P AT 1.35 A RESOLUTION
Descriptor: GTP-BINDING PROTEIN YPT7P, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
Authors:Constantinescu, A.-T, Rak, A, Scheidig, A.J.
Deposit date:2002-02-02
Release date:2002-06-05
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Rab-subfamily-specific regions of Ypt7p are structurally different from other RabGTPases.
Structure, 10, 2002
1NF1
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BU of 1nf1 by Molmil
THE GAP RELATED DOMAIN OF NEUROFIBROMIN
Descriptor: PROTEIN (NEUROFIBROMIN)
Authors:Scheffzek, K, Ahmadian, M.R, Wiesmueller, L, Kabsch, W, Stege, P, Schmitz, F, Wittinghofer, A.
Deposit date:1998-07-08
Release date:1999-07-20
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural analysis of the GAP-related domain from neurofibromin and its implications.
EMBO J., 17, 1998
3SK2
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BU of 3sk2 by Molmil
Crystal structure of phenazine resistance protein EhpR from Enterobacter agglomerans (Erwinia herbicola, Pantoea agglomerans) Eh1087 in complex with griseoluteic acid
Descriptor: 6-formyl-9-methoxyphenazine-1-carboxylic acid, EhpR
Authors:Blankenfeldt, W, Yu, S.
Deposit date:2011-06-22
Release date:2011-08-31
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.01 Å)
Cite:Atomic resolution structure of EhpR: phenazine resistance in Enterobacter agglomerans Eh1087 follows principles of bleomycin / mitomycin C resistance in other bacteria.
Bmc Struct.Biol., 11, 2011
3SK1
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BU of 3sk1 by Molmil
Crystal structure of phenazine resistance protein EhpR from Enterobacter agglomerans (Erwinia herbicola, Pantoea agglomerans) Eh1087, apo form
Descriptor: EhpR
Authors:Blankenfeldt, W, Yu, S.
Deposit date:2011-06-22
Release date:2011-08-31
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Atomic resolution structure of EhpR: phenazine resistance in Enterobacter agglomerans Eh1087 follows principles of bleomycin / mitomycin C resistance in other bacteria.
Bmc Struct.Biol., 11, 2011
5TMP
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BU of 5tmp by Molmil
COMPLEX OF E. COLI THYMIDYLATE KINASE WITH THE BISUBSTRATE INHIBITOR AZTP5A
Descriptor: P1-(5'-ADENOSYL)P5-(5'-(3'AZIDO-3'-DEOXYTHYMIDYL))PENTAPHOSPHATE, PROTEIN (THYMIDYLATE KINASE)
Authors:Lavie, A, Ostermann, N, Schlichting, I.
Deposit date:1998-09-01
Release date:1998-11-25
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Structural basis for efficient phosphorylation of 3'-azidothymidine monophosphate by Escherichia coli thymidylate kinase.
Proc.Natl.Acad.Sci.USA, 95, 1998
4F38
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BU of 4f38 by Molmil
Crystal structure of geranylgeranylated RhoA in complex with RhoGDI in its active GPPNHP-bound form
Descriptor: GERAN-8-YL GERAN, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
Authors:Guo, Z, Tnimov, Z, Alexandrov, K.
Deposit date:2012-05-09
Release date:2012-05-23
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Quantitative Analysis of Prenylated RhoA Interaction with Its Chaperone, RhoGDI.
J.Biol.Chem., 287, 2012
621P
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BU of 621p by Molmil
THREE-DIMENSIONAL STRUCTURES OF H-RAS P21 MUTANTS: MOLECULAR BASIS FOR THEIR INABILITY TO FUNCTION AS SIGNAL SWITCH MOLECULES
Descriptor: H-RAS P21 PROTEIN, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
Authors:Krengel, U, Scherer, A, Kabsch, W, Wittinghofer, A, Pai, E.F.
Deposit date:1991-06-06
Release date:1994-01-31
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Three-dimensional structures of H-ras p21 mutants: molecular basis for their inability to function as signal switch molecules.
Cell(Cambridge,Mass.), 62, 1990
721P
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BU of 721p by Molmil
THREE-DIMENSIONAL STRUCTURES OF H-RAS P21 MUTANTS: MOLECULAR BASIS FOR THEIR INABILITY TO FUNCTION AS SIGNAL SWITCH MOLECULES
Descriptor: H-RAS P21 PROTEIN, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
Authors:Krengel, U, Scherer, A, Kabsch, W, Wittinghofer, A, Pai, E.F.
Deposit date:1991-06-06
Release date:1994-01-31
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Three-dimensional structures of H-ras p21 mutants: molecular basis for their inability to function as signal switch molecules.
Cell(Cambridge,Mass.), 62, 1990

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