1NF1
THE GAP RELATED DOMAIN OF NEUROFIBROMIN
Summary for 1NF1
Entry DOI | 10.2210/pdb1nf1/pdb |
Descriptor | PROTEIN (NEUROFIBROMIN) (1 entity in total) |
Functional Keywords | neurofibromin, type i neurofibromatosis, nf1, ras, gap, signal transduction, cancer, growth regulation, gtp hydrolysis, patient mutation, arginine finger, signaling protein |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus : P21359 |
Total number of polymer chains | 1 |
Total formula weight | 37982.67 |
Authors | Scheffzek, K.,Ahmadian, M.R.,Wiesmueller, L.,Kabsch, W.,Stege, P.,Schmitz, F.,Wittinghofer, A. (deposition date: 1998-07-08, release date: 1999-07-20, Last modification date: 2023-12-27) |
Primary citation | Scheffzek, K.,Ahmadian, M.R.,Wiesmuller, L.,Kabsch, W.,Stege, P.,Schmitz, F.,Wittinghofer, A. Structural analysis of the GAP-related domain from neurofibromin and its implications. EMBO J., 17:4313-4327, 1998 Cited by PubMed: 9687500DOI: 10.1093/emboj/17.15.4313 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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