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1WQ1

RAS-RASGAP COMPLEX

Summary for 1WQ1
Entry DOI10.2210/pdb1wq1/pdb
DescriptorH-RAS, P120GAP, MAGNESIUM ION, ... (6 entities in total)
Functional Keywordsras, gap, signal transduction, growth regulation, gtp hydrolysis, transition state, complex (gtp-binding-gtpase activation), complex (gtp-binding-gtpase activation) complex, complex (gtp-binding/gtpase activation)
Biological sourceHomo sapiens (human)
More
Cellular locationCell membrane; Lipid-anchor; Cytoplasmic side: P01112
Cytoplasm: P20936
Total number of polymer chains2
Total formula weight57649.95
Authors
Scheffzek, K.,Ahmadian, M.R.,Kabsch, W.,Wiesmueller, L.,Lautwein, A.,Schmitz, F.,Wittinghofer, A. (deposition date: 1997-07-03, release date: 1998-07-15, Last modification date: 2023-08-09)
Primary citationScheffzek, K.,Ahmadian, M.R.,Kabsch, W.,Wiesmuller, L.,Lautwein, A.,Schmitz, F.,Wittinghofer, A.
The Ras-RasGAP complex: structural basis for GTPase activation and its loss in oncogenic Ras mutants.
Science, 277:333-338, 1997
Cited by
PubMed: 9219684
DOI: 10.1126/science.277.5324.333
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.5 Å)
Structure validation

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