2WFD
| Structure of the human cytosolic leucyl-tRNA synthetase editing domain | Descriptor: | LEUCYL-TRNA SYNTHETASE, CYTOPLASMIC | Authors: | Seiradake, E, Mao, W, Hernandez, V, Baker, S.J, Plattner, J.J, Alley, M.R.K, Cusack, S. | Deposit date: | 2009-04-03 | Release date: | 2009-05-19 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (3.25 Å) | Cite: | Crystal Structures of the Human and Fungal Cytosolic Leucyl-tRNA Synthetase Editing Domains: A Structural Basis for the Rational Design of Antifungal Benzoxaboroles. J.Mol.Biol., 390, 2009
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2VTW
| Structure of the C-terminal head domain of the fowl adenovirus type 1 short fibre | Descriptor: | FIBER PROTEIN 2, GLYCEROL, SULFATE ION | Authors: | ElBakkouri, M, Seiradake, E, Cusack, S, Ruigrok, R.W.H, Schoehn, G. | Deposit date: | 2008-05-16 | Release date: | 2008-06-17 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure of the C-Terminal Head Domain of the Fowl Adenovirus Type 1 Short Fibre. Virology, 378, 2008
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2WFH
| The Human Slit 2 Dimerization Domain D4 | Descriptor: | SLIT HOMOLOG 2 PROTEIN C-PRODUCT, SULFATE ION | Authors: | Seiradake, E, von Philipsborn, A.C, Henry, M, Fritz, M, Lortat-Jacob, H, Jamin, M, Hemrika, W, Bastmeyer, M, Cusack, S, McCarthy, A.A. | Deposit date: | 2009-04-06 | Release date: | 2009-04-21 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structure and functional relevance of the Slit2 homodimerization domain. EMBO Rep., 10, 2009
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2WFE
| Structure of the Candida albicans cytosolic leucyl-tRNA synthetase editing domain | Descriptor: | CYTOSOLIC LEUCYL-TRNA SYNTHETASE | Authors: | Seiradake, E, Mao, W, Hernandez, V, Baker, S.J, Plattner, J.J, Alley, M.R.K, Cusack, S. | Deposit date: | 2009-04-04 | Release date: | 2009-05-19 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal Structures of the Human and Fungal Cytosolic Leucyl-tRNA Synthetase Editing Domains: A Structural Basis for the Rational Design of Antifungal Benzoxaboroles. J.Mol.Biol., 390, 2009
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2VY8
| The 627-domain from influenza A virus polymerase PB2 subunit with Glu- 627 | Descriptor: | POLYMERASE BASIC PROTEIN 2 | Authors: | Tarendeau, F, Crepin, T, Guilligay, D, Ruigrok, R, Cusack, S, Hart, D. | Deposit date: | 2008-07-19 | Release date: | 2008-09-09 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Host Determinant Residue Lysine 627 Lies on the Surface of a Discrete, Folded Domain of Influenza Virus Polymerase Pb2 Subunit Plos Pathog., 4, 2008
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2VY6
| Two domains from the C-terminal region of influenza A virus polymerase PB2 subunit | Descriptor: | POLYMERASE BASIC PROTEIN 2 | Authors: | Tarendeau, F, Crepin, T, Guilligay, D, Ruigrok, R, Cusack, S, Hart, D. | Deposit date: | 2008-07-18 | Release date: | 2008-09-09 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Host Determinant Residue Lysine 627 Lies on the Surface of a Discrete, Folded Domain of Influenza Virus Polymerase Pb2 Subunit Plos Pathog., 4, 2008
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2W4S
| novel RNA-binding domain in Cryptosporidium parvum at 2.5 angstrom resolution | Descriptor: | Ankyrin-repeat protein | Authors: | Varrot, A, Mackereth, C, Mourao, A, Sattler, M, Cusack, S. | Deposit date: | 2008-12-02 | Release date: | 2009-12-29 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Structure and RNA Recognition by the Snrna and Snorna Transport Factor Phax. RNA, 16, 2010
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2W69
| Influenza polymerase fragment | Descriptor: | MANGANESE (II) ION, POLYMERASE ACIDIC PROTEIN, SULFATE ION | Authors: | Dias, A, Bouvier, D, Crepin, T, McCarthy, A.A, Hart, D.J, Baudin, F, Cusack, S, Ruigrok, R.W.H. | Deposit date: | 2008-12-17 | Release date: | 2009-02-03 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | The CAP-Snatching Endonuclease of Influenza Virus Polymerase Resides in the Pa Subunit Nature, 458, 2009
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2WFG
| Structure of the Candida albicans cytosolic leucyl-tRNA synthetase editing domain bound to a benzoxaborole-AMP adduct | Descriptor: | CYTOSOLIC LEUCYL-TRNA SYNTHETASE, [(1S,3S,5R,6R,8R)-6-(6-AMINOPURIN-9-YL)-4'-ETHYLAMINO-3'-FLUORO-SPIRO[2,4,7-TRIOXA-3-BORANUIDABICYCLO[3.3.0]OCTANE-3,7'-8-OXA-7-BORANUIDABICYCLO[4.3.0]NONA-1,3,5-TRIENE]-8-YL]METHYL DIHYDROGEN PHOSPHATE | Authors: | Seiradake, E, Mao, W, Hernandez, V, Baker, S.J, Plattner, J.J, Alley, M.R.K, Cusack, S. | Deposit date: | 2009-04-05 | Release date: | 2009-05-19 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal Structures of the Human and Fungal Cytosolic Leucyl-tRNA Synthetase Editing Domains: A Structural Basis for the Rational Design of Antifungal Benzoxaboroles. J.Mol.Biol., 390, 2009
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2WJY
| Crystal structure of the complex between human nonsense mediated decay factors UPF1 and UPF2 Orthorhombic form | Descriptor: | REGULATOR OF NONSENSE TRANSCRIPTS 1, SULFATE ION, ZINC ION | Authors: | Clerici, M, Mourao, A, Gutsche, I, Gehring, N.H, Hentze, M.W, Kulozik, A, Kadlec, J, Sattler, M, Cusack, S. | Deposit date: | 2009-06-01 | Release date: | 2009-07-07 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Unusual Bipartite Mode of Interaction between the Nonsense-Mediated Decay Factors, Upf1 and Upf2. Embo J., 28, 2009
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2WJV
| Crystal structure of the complex between human nonsense mediated decay factors UPF1 and UPF2 | Descriptor: | REGULATOR OF NONSENSE TRANSCRIPTS 1, REGULATOR OF NONSENSE TRANSCRIPTS 2, SULFATE ION, ... | Authors: | Clerici, M, Mourao, A, Gutsche, I, Gehring, N.H, Hentze, M.W, Kulozik, A, Kadlec, J, Sattler, M, Cusack, S. | Deposit date: | 2009-06-01 | Release date: | 2009-07-07 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Unusual Bipartite Mode of Interaction between the Nonsense-Mediated Decay Factors, Upf1 and Upf2. Embo J., 28, 2009
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2XI5
| N-terminal endonuclease domain of La Crosse virus L-protein | Descriptor: | MANGANESE (II) ION, RNA POLYMERASE L | Authors: | Reguera, J, Weber, F, Cusack, S. | Deposit date: | 2010-06-28 | Release date: | 2010-10-06 | Last modified: | 2012-07-18 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Bunyaviridae RNA Polymerases (L-Protein) Have an N-Terminal, Influenza-Like Endonuclease Domain, Essential for Viral CAP-Dependent Transcription. Plos Pathog., 6, 2010
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2XI7
| N-terminal endonuclease domain of La Crosse virus L-protein | Descriptor: | 2-4-DIOXO-4-PHENYLBUTANOIC ACID, MANGANESE (II) ION, RNA POLYMERASE L | Authors: | Reguera, J, Weber, F, Cusack, S. | Deposit date: | 2010-06-28 | Release date: | 2010-10-06 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Bunyaviridae RNA Polymerases (L-Protein) Have an N-Terminal, Influenza-Like Endonuclease Domain, Essential for Viral CAP-Dependent Transcription. Plos Pathog., 6, 2010
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3ZIU
| Crystal structure of Mycoplasma mobile Leucyl-tRNA Synthetase with Leu-AMS in the active site | Descriptor: | 5'-O-(L-leucylsulfamoyl)adenosine, GLYCEROL, LEUCYL-TRNA SYNTHETASE | Authors: | Li, L, Palencia, A, Lukk, T, Li, Z, Luthey-Schulten, Z.A, Cusack, S, Martinis, S.A, Boniecki, M.T. | Deposit date: | 2013-01-10 | Release date: | 2013-02-27 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.07 Å) | Cite: | Leucyl-tRNA Synthetase Editing Domain Functions as a Molecular Rheostat to Control Codon Ambiguity in Mycoplasma Pathogens. Proc.Natl.Acad.Sci.USA, 110, 2013
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4A2Q
| Structure of duck RIG-I tandem CARDs and helicase domain | Descriptor: | RETINOIC ACID INDUCIBLE PROTEIN I | Authors: | Kowalinski, E, Lunardi, T, McCarthy, A.A, Cusack, S. | Deposit date: | 2011-09-28 | Release date: | 2011-10-19 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Structural Basis for the Activation of Innate Immune Pattern Recognition Receptor Rig-I by Viral RNA. Cell(Cambridge,Mass.), 147, 2011
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4ARC
| Ternary complex of E. coli leucyl-tRNA synthetase, tRNA(leu) and leucine in the editing conformation | Descriptor: | LEUCINE, LEUCINE--TRNA LIGASE, MAGNESIUM ION, ... | Authors: | Palencia, A, Crepin, T, Vu, M.T, Lincecum Jr, T.L, Martinis, S.A, Cusack, S. | Deposit date: | 2012-04-23 | Release date: | 2012-06-13 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural Dynamics of the Aminoacylation and Proofreading Functional Cycle of Bacterial Leucyl-tRNA Synthetase Nat.Struct.Mol.Biol., 19, 2012
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4AQ7
| Ternary complex of E. coli leucyl-tRNA synthetase, tRNA(leu) and leucyl-adenylate analogue in the aminoacylation conformation | Descriptor: | E. COLI TRNALEU UAA ISOACCEPTOR, LEUCINE, LEUCINE--TRNA LIGASE, ... | Authors: | Palencia, A, Crepin, T, Vu, M.T, Lincecum Jr, T.L, Martinis, S.A, Cusack, S. | Deposit date: | 2012-04-13 | Release date: | 2012-06-13 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural Dynamics of the Aminoacylation and Proofreading Functional Cycle of Bacterial Leucyl-tRNA Synthetase Nat.Struct.Mol.Biol., 19, 2012
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4A2V
| Structure of duck RIG-I C-terminal domain (CTD) | Descriptor: | GLYCEROL, RETINOIC ACID INDUCIBLE PROTEIN I, ZINC ION | Authors: | Kowalinski, E, Lunardi, T, McCarthy, A.A, Cusack, S. | Deposit date: | 2011-09-29 | Release date: | 2011-10-19 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.44 Å) | Cite: | Structural Basis for the Activation of Innate Immune Pattern Recognition Receptor Rig-I by Viral RNA. Cell(Cambridge,Mass.), 147, 2011
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4A2W
| Structure of full-length duck RIG-I | Descriptor: | RETINOIC ACID INDUCIBLE PROTEIN I | Authors: | Kowalinski, E, Lunardi, T, McCarthy, A.A, Cusack, S. | Deposit date: | 2011-09-29 | Release date: | 2011-10-19 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (3.7 Å) | Cite: | Structural Basis for the Activation of Innate Immune Pattern Recognition Receptor Rig-I by Viral RNA. Cell(Cambridge,Mass.), 147, 2011
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4A2X
| Structure of duck RIG-I C-terminal domain (CTD) with 14-mer dSRNA | Descriptor: | 5'-R(*CP*GP*CP*GP*UP*UP*GP*UP*UP*CP*UP*CP*CP*CP)-3', 5'-R(*GP*GP*GP*AP*GP*AP*AP*CP*AP*AP*CP*GP*CP*GP)-3', RETINOIC ACID INDUCIBLE PROTEIN I, ... | Authors: | Kowalinski, E, Lunardi, T, McCarthy, A.A, Cusack, S. | Deposit date: | 2011-09-29 | Release date: | 2011-10-19 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (4 Å) | Cite: | Structural basis for the activation of innate immune pattern-recognition receptor RIG-I by viral RNA. Cell, 147, 2011
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4AQQ
| Dodecahedron formed of penton base protein from adenovirus Ad3 | Descriptor: | CALCIUM ION, L2 PROTEIN III (PENTON BASE) | Authors: | Burmeister, W.P, Szolajska, E, Zochowska, M, Nerlo, B, Andreev, I, Schoehn, G, Andrieu, J.-P, Fender, P, Naskalska, A, Zubieta, C, Cusack, S, Chroboczek, J. | Deposit date: | 2012-04-19 | Release date: | 2012-10-24 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (4.75 Å) | Cite: | The Structural Basis for the Integrity of Adenovirus Ad3 Dodecahedron. Plos One, 7, 2012
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4A36
| Structure of duck RIG-I helicase domain bound to 19-mer dsRNA and ATP transition state analogue | Descriptor: | 5'-R(*GP*CP*AP*UP*GP*CP*GP*AP*CP*CP*UP*CP*UP*GP *UP*UP*UP*GP*A)-3', 5'-R(*UP*CP*AP*AP*AP*CP*AP*GP*AP*GP*GP*UP*CP*GP *CP*AP*UP*GP*C)-3', ADENOSINE-5'-DIPHOSPHATE, ... | Authors: | Kowalinski, E, Lunardi, T, McCarthy, A.A, Cusack, S. | Deposit date: | 2011-09-30 | Release date: | 2011-10-19 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.7 Å) | Cite: | Structural Basis for the Activation of Innate Immune Pattern Recognition Receptor Rig-I by Viral RNA. Cell(Cambridge,Mass.), 147, 2011
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4AR2
| Dodecahedron formed of penton base protein from adenovirus Ad3 | Descriptor: | CALCIUM ION, FIBER PROTEIN, L2 PROTEIN III (PENTON BASE) | Authors: | Burmeister, W.P, Szolajska, E, Zochowska, M, Nerlo, B, Andreev, I, Schoehn, G, Andrieu, J.-P, Fender, P, Naskalska, A, Zubieta, C, Cusack, S, Chroboczek, J. | Deposit date: | 2012-04-20 | Release date: | 2012-10-24 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.8 Å) | Cite: | The Structural Basis for the Integrity of Adenovirus Ad3 Dodecahedron. Plos One, 7, 2012
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4A2P
| Structure of duck RIG-I helicase domain | Descriptor: | RETINOIC ACID INDUCIBLE PROTEIN I | Authors: | Kowalinski, E, Lunardi, T, McCarthy, A.A, Cusack, S. | Deposit date: | 2011-09-28 | Release date: | 2011-10-19 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural Basis for the Activation of Innate Immune Pattern Recognition Receptor Rig-I by Viral RNA. Cell(Cambridge,Mass.), 147, 2011
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4AVL
| Influenza strain pH1N1 2009 polymerase subunit PA endonuclease in complex with dTMP | Descriptor: | MANGANESE (II) ION, POLYMERASE PA, THYMIDINE-5'-PHOSPHATE | Authors: | Kowalinski, E, Zubieta, C, Wolkerstorfer, A, Szolar, O.H.J, Ruigrok, R.W.H, Cusack, S. | Deposit date: | 2012-05-28 | Release date: | 2012-08-22 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.87 Å) | Cite: | Structural Analysis of Specific Metal Chelating Inhibitor Binding to the Endonuclease Domain of Influenza Ph1N1 (2009) Polymerase. Plos Pathog., 8, 2012
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