4AQ7

Ternary complex of E. coli leucyl-tRNA synthetase, tRNA(leu) and leucyl-adenylate analogue in the aminoacylation conformation

Summary for 4AQ7

Entry DOI	10.2210/pdb4aq7/pdb
Related	2AJG 2AJH 2AJI 4ARC 4ARI 4AS1
Descriptor	LEUCINE--TRNA LIGASE, E. COLI TRNALEU UAA ISOACCEPTOR, ZINC ION, ... (7 entities in total)
Functional Keywords	ligase-rna complex, ligase, nucleotide(atp)-binding, protein biosynthesis, class i aminoacyl-trna synthetase, atp-binding, metal-binding, ligase/rna
Biological source	ESCHERICHIA COLI More
Cellular location	Cytoplasm: P07813
Total number of polymer chains	4
Total formula weight	256271.75
Authors	Palencia, A.,Crepin, T.,Vu, M.T.,Lincecum Jr, T.L.,Martinis, S.A.,Cusack, S. (deposition date: 2012-04-13, release date: 2012-06-13, Last modification date: 2023-12-20)
Primary citation	Palencia, A.,Crepin, T.,Vu, M.T.,Lincecum Jr, T.L.,Martinis, S.A.,Cusack, S. Structural Dynamics of the Aminoacylation and Proofreading Functional Cycle of Bacterial Leucyl-tRNA Synthetase Nat.Struct.Mol.Biol., 19:677-, 2012 Cited by PubMed: 22683997 DOI: 10.1038/NSMB.2317 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation