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3I2T
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BU of 3i2t by Molmil
Crystal structure of the unliganded Drosophila Epidermal Growth Factor Receptor ectodomain
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Epidermal growth factor receptor, ...
Authors:Alvarado, D, Klein, D.E, Lemmon, M.A.
Deposit date:2009-06-29
Release date:2009-09-08
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:ErbB2 resembles an autoinhibited invertebrate epidermal growth factor receptor.
Nature, 461, 2009
3LTG
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BU of 3ltg by Molmil
Crystal structure of the Drosophila Epidermal Growth Factor Receptor ectodomain complexed with a low affinity Spitz mutant
Descriptor: Epidermal growth factor receptor, Protein spitz
Authors:Alvarado, D, Klein, D.E, Lemmon, M.A.
Deposit date:2010-02-15
Release date:2010-08-25
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structural basis for negative cooperativity in growth factor binding to an EGF receptor.
Cell(Cambridge,Mass.), 142, 2010
3LTF
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BU of 3ltf by Molmil
Crystal Structure of the Drosophila Epidermal Growth Factor Receptor ectodomain in complex with Spitz
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Epidermal growth factor receptor, ...
Authors:Alvarado, D, Klein, D.E, Lemmon, M.A.
Deposit date:2010-02-15
Release date:2010-08-25
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural basis for negative cooperativity in growth factor binding to an EGF receptor.
Cell(Cambridge,Mass.), 142, 2010
3GOP
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BU of 3gop by Molmil
Crystal structure of the EGF receptor juxtamembrane and kinase domains
Descriptor: Epidermal growth factor receptor
Authors:Choi, S.H, Alvarado, D, Moravcevic, K, Lemmon, M.A.
Deposit date:2009-03-19
Release date:2009-07-07
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The juxtamembrane region of the EGF receptor functions as an activation domain.
Mol.Cell, 34, 2009
4WPC
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BU of 4wpc by Molmil
Crystal structure of Rgd1p F-BAR domain in complex with inositol phosphate
Descriptor: INOSITOL HEXAKISPHOSPHATE, RHO GTPase-activating protein RGD1
Authors:Moravcevic, K, Lemmon, M.A.
Deposit date:2014-10-17
Release date:2014-12-24
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.34 Å)
Cite:Comparison of Saccharomyces cerevisiae F-BAR Domain Structures Reveals a Conserved Inositol Phosphate Binding Site.
Structure, 23, 2015
4WPE
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BU of 4wpe by Molmil
Crystal Structure of Hof1p F-BAR domain
Descriptor: Cytokinesis protein 2
Authors:Lemmon, M.A, Moravcevic, K.
Deposit date:2014-10-17
Release date:2014-12-24
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Comparison of Saccharomyces cerevisiae F-BAR Domain Structures Reveals a Conserved Inositol Phosphate Binding Site.
Structure, 23, 2015
5CUS
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BU of 5cus by Molmil
Crystal Structure of sErbB3-Fab3379 Complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab LC region of KTN3379, IgG H chain, ...
Authors:Lee, S, Schlessinger, J.
Deposit date:2015-07-25
Release date:2015-10-14
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Inhibition of ErbB3 by a monoclonal antibody that locks the extracellular domain in an inactive configuration.
Proc.Natl.Acad.Sci.USA, 112, 2015
7LS0
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BU of 7ls0 by Molmil
Structure of the Human ALK GRD bound to AUG
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ALK tyrosine kinase receptor fused with ALK and LTK ligand 2, CITRIC ACID
Authors:Stayrook, S, Li, T, Klein, D.E.
Deposit date:2021-02-17
Release date:2021-11-24
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Structural basis for ligand reception by anaplastic lymphoma kinase.
Nature, 600, 2021
7LRZ
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BU of 7lrz by Molmil
Structure of the Human ALK GRD
Descriptor: ALK tyrosine kinase receptor
Authors:Stayrook, S, Li, T, Klein, D.E.
Deposit date:2021-02-17
Release date:2021-11-24
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Structural basis for ligand reception by anaplastic lymphoma kinase.
Nature, 600, 2021
7MK7
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BU of 7mk7 by Molmil
Augmentor domain of augmentor-beta
Descriptor: ALK and LTK ligand 1,Maltodextrin-binding protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
Authors:Krimmer, S.G, Reshetnyak, A.V, Puleo, D.E, Schlessinger, J.
Deposit date:2021-04-21
Release date:2021-11-24
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.42815185 Å)
Cite:Structural basis for ligand reception by anaplastic lymphoma kinase.
Nature, 600, 2021
7LIR
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BU of 7lir by Molmil
Structure of the invertebrate ALK GRD
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ALK tyrosine kinase receptor homolog scd-2, ...
Authors:Stayrook, S, Li, T, Klein, D.E.
Deposit date:2021-01-27
Release date:2021-11-24
Last modified:2021-12-15
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis for ligand reception by anaplastic lymphoma kinase.
Nature, 600, 2021

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