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3I2T

Crystal structure of the unliganded Drosophila Epidermal Growth Factor Receptor ectodomain

Summary for 3I2T
Entry DOI10.2210/pdb3i2t/pdb
DescriptorEpidermal growth factor receptor, isoform A, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
Functional Keywordsdrosophila, egfr, ectodomain, unliganded, autoinhibited, atp-binding, nucleotide-binding, tyrosine-protein kinase, transferase
Biological sourceDrosophila melanogaster (Fruit fly)
Total number of polymer chains1
Total formula weight65060.16
Authors
Alvarado, D.,Klein, D.E.,Lemmon, M.A. (deposition date: 2009-06-29, release date: 2009-09-08, Last modification date: 2023-09-06)
Primary citationAlvarado, D.,Klein, D.E.,Lemmon, M.A.
ErbB2 resembles an autoinhibited invertebrate epidermal growth factor receptor.
Nature, 461:287-291, 2009
Cited by
PubMed: 19718021
DOI: 10.1038/nature08297
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.7 Å)
Structure validation

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