3I2T
Crystal structure of the unliganded Drosophila Epidermal Growth Factor Receptor ectodomain
Summary for 3I2T
Entry DOI | 10.2210/pdb3i2t/pdb |
Descriptor | Epidermal growth factor receptor, isoform A, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total) |
Functional Keywords | drosophila, egfr, ectodomain, unliganded, autoinhibited, atp-binding, nucleotide-binding, tyrosine-protein kinase, transferase |
Biological source | Drosophila melanogaster (Fruit fly) |
Total number of polymer chains | 1 |
Total formula weight | 65060.16 |
Authors | Alvarado, D.,Klein, D.E.,Lemmon, M.A. (deposition date: 2009-06-29, release date: 2009-09-08, Last modification date: 2023-09-06) |
Primary citation | Alvarado, D.,Klein, D.E.,Lemmon, M.A. ErbB2 resembles an autoinhibited invertebrate epidermal growth factor receptor. Nature, 461:287-291, 2009 Cited by PubMed: 19718021DOI: 10.1038/nature08297 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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