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1P2P
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BU of 1p2p by Molmil
STRUCTURE OF PORCINE PANCREATIC PHOSPHOLIPASE A2 AT 2.6 ANGSTROMS RESOLUTION AND COMPARISON WITH BOVINE PHOSPHOLIPASE A2
Descriptor: CALCIUM ION, PHOSPHOLIPASE A2
Authors:Dijkstra, B.W, Renetseder, R, Kalk, K.H, Hol, W.G.J, Drenth, J.
Deposit date:1983-06-27
Release date:1983-09-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of porcine pancreatic phospholipase A2 at 2.6 A resolution and comparison with bovine phospholipase A2.
J.Mol.Biol., 168, 1983
1MU7
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BU of 1mu7 by Molmil
Crystal Structure of a Human Tyrosyl-DNA Phosphodiesterase (Tdp1)-Tungstate Complex
Descriptor: GLYCEROL, TUNGSTATE(VI)ION, Tyrosyl-DNA Phosphodiesterase
Authors:Davies, D.R, Interthal, H, Champoux, J.J, Hol, W.G.J.
Deposit date:2002-09-23
Release date:2003-01-07
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Insights Into Substrate Binding and Catalytic Mechanism of Human Tyrosyl-DNA Phosphodiesterase (Tdp1) from Vanadate- and Tungstate-Inhibited Structures
J.Mol.Biol., 324, 2003
1MU9
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BU of 1mu9 by Molmil
Crystal Structure of a Human Tyrosyl-DNA Phosphodiesterase (Tdp1)-Vanadate Complex
Descriptor: GLYCEROL, Tyrosyl-DNA Phosphodiesterase, VANADATE ION
Authors:Davies, D.R, Interthal, H, Champoux, J.J, Hol, W.G.J.
Deposit date:2002-09-23
Release date:2003-01-07
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Insights Into Substrate Binding and Catalytic Mechanism of Human Tyrosyl-DNA Phosphodiesterase (Tdp1) from Vanadate- and Tungstate-Inhibited Structures
J.Mol.Biol., 324, 2002
1IVY
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BU of 1ivy by Molmil
PHYSIOLOGICAL DIMER HPP PRECURSOR
Descriptor: 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Rudenko, G, Bonten, E, D'Azzo, A, Hol, W.G.J.
Deposit date:1996-06-12
Release date:1997-04-21
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Three-dimensional structure of the human 'protective protein': structure of the precursor form suggests a complex activation mechanism.
Structure, 3, 1995
1NOL
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BU of 1nol by Molmil
OXYGENATED HEMOCYANIN (SUBUNIT TYPE II)
Descriptor: CALCIUM ION, COPPER (II) ION, HEMOCYANIN (SUBUNIT TYPE II), ...
Authors:Hazes, B, Hol, W.G.J.
Deposit date:1995-10-17
Release date:1996-03-08
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of deoxygenated Limulus polyphemus subunit II hemocyanin at 2.18 A resolution: clues for a mechanism for allosteric regulation.
Protein Sci., 2, 1993
5V49
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BU of 5v49 by Molmil
Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor (Chem 1917)
Descriptor: GLYCEROL, METHIONINE, Methionyl-tRNA synthetase, ...
Authors:Barros-Alvarez, X, Hol, W.G.J.
Deposit date:2017-03-08
Release date:2017-07-26
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Optimization of a binding fragment targeting the "enlarged methionine pocket" leads to potent Trypanosoma brucei methionyl-tRNA synthetase inhibitors.
Bioorg. Med. Chem. Lett., 27, 2017
5USF
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BU of 5usf by Molmil
Leishmania donovani tyrosyl-tRNA synthetase in complex with nanobody and inhibitor
Descriptor: 5'-O-[N-(L-TYROSYL)SULFAMOYL]ADENOSINE, Immunoglobulin heavy chain variable region, Tyrosyl-tRNA synthetase, ...
Authors:Barros-Alvarez, X, Hol, W.G.J.
Deposit date:2017-02-13
Release date:2017-05-17
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Leishmania donovani tyrosyl-tRNA synthetase structure in complex with a tyrosyl adenylate analog and comparisons with human and protozoan counterparts.
Biochimie, 138, 2017
1P9W
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BU of 1p9w by Molmil
Crystal Structure of Vibrio cholerae putative NTPase EpsE
Descriptor: General secretion pathway protein E, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ZINC ION
Authors:Robien, M.A, Krumm, B.E, Sandkvist, M, Hol, W.G.J.
Deposit date:2003-05-12
Release date:2003-10-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of the extracellular protein secretion NTPase EpsE of Vibrio cholerae
J.Mol.Biol., 333, 2003
1M66
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Crystal Structure of Leishmania mexicana GPDH Complexed with Inhibitor 2-bromo-6-chloro-purine
Descriptor: 2-BROMO-6-CHLORO-PURINE, Glycerol-3-phosphate dehydrogenase, PALMITIC ACID
Authors:Choe, J, Suresh, S, Wisedchaisri, G, Kennedy, K.J, Gelb, M.H, Hol, W.G.J.
Deposit date:2002-07-12
Release date:2002-12-11
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Anomalous differences of light elements in determining precise binding modes of ligands to glycerol-3-phosphate dehydrogenase
Chem.Biol., 9, 2002
1P9R
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BU of 1p9r by Molmil
Crystal Structure of Vibrio cholerae putative NTPase EpsE
Descriptor: CHLORIDE ION, General secretion pathway protein E, ZINC ION
Authors:Robien, M.A, Krumm, B.E, Sandkvist, M, Hol, W.G.J.
Deposit date:2003-05-12
Release date:2003-10-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of the extracellular protein secretion NTPase EpsE of Vibrio cholerae
J.Mol.Biol., 333, 2003
1N1E
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Crystal structure of Leishmania mexicana Glycerol-3-phosphate dehydrogenase complexed with DHAP and NAD
Descriptor: ADENOSINE 5'-(TRIHYDROGEN DIPHOSPHATE) P'-5'-ESTER WITH 3-(AMINOCARBONYL)-4-(1-HYDROXYL-2-OXO-3-PHOSPHONOOXY-PROPYL)-1-BETA-D-RIBOFURANOSYLPYRIDINIUM INNER SALT, glycerol-3-phosphate dehydrogenase
Authors:Choe, J, Hol, W.G.J.
Deposit date:2002-10-17
Release date:2003-05-27
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Leishmania mexicana Glycerol-3-phosphate Dehydrogenase Showed Conformational Changes Upon Binding a Bi-substrate Adduct
J.Mol.Biol., 320, 2003
1N57
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Crystal Structure of Chaperone Hsp31
Descriptor: Chaperone Hsp31, MAGNESIUM ION
Authors:Quigley, P.M, Korotkov, K, Baneyx, F, Hol, W.G.J.
Deposit date:2002-11-04
Release date:2003-03-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The 1.6A Crystal Structure of the Class of Chaperone Represented by Escherichia coli Hsp31 Reveals a Putative Catalytic Triad
Proc.Natl.Acad.Sci.USA, 100, 2003
1PZJ
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BU of 1pzj by Molmil
Cholera Toxin B-Pentamer Complexed With Nitrophenyl Galactoside 5
Descriptor: Cholera Toxin B Subunit, N-{3-[4-(3-AMINO-PROPYL)-PIPERAZIN-1-YL]-PROPYL}-3-NITRO-5-(GALACTOPYRANOSYL)-ALPHA-BENZAMIDE, N-{3-[4-(3-AMINO-PROPYL)-PIPERAZIN-1-YL]-PROPYL}-3-NITRO-5-(GALACTOPYRANOSYL)-BETA-BENZAMIDE
Authors:Mitchell, D.D, Pickens, J.C, Korotkov, K, Fan, E, Hol, W.G.J.
Deposit date:2003-07-11
Release date:2004-03-09
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.46 Å)
Cite:3,5-Substituted phenyl galactosides as leads in designing effective cholera toxin antagonists; synthesis and crystallographic studies
Bioorg.Med.Chem., 12, 2004
1M67
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Crystal Structure of Leishmania mexicana GPDH Complexed with Inhibitor 2-bromo-6-hydroxy-purine
Descriptor: 2-BROMO-6-HYDROXY-PURINE, Glycerol-3-phosphate dehydrogenase, PALMITIC ACID
Authors:Choe, J, Suresh, S, Wisedchaisri, G, Kennedy, K.J, Gelb, M.H, Hol, W.G.J.
Deposit date:2002-07-12
Release date:2002-12-11
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Anomalous differences of light elements in determining precise binding modes of ligands to glycerol-3-phosphate dehydrogenase
Chem.Biol., 9, 2002
1PZI
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BU of 1pzi by Molmil
Heat-Labile Enterotoxin B-Pentamer Complexed With Nitrophenyl Galactoside 2a
Descriptor: Heat-labile Enterotoxin B subunit, N-(2-MORPHOLIN-4-YL-1-MORPHOLIN-4-YLMETHYL-ETHYL)-3-NITRO-5-(3,4,5-TRIHYDROXY-6-HYDROXYMETHYL-TETRAHYDRO-PYRAN-2-YLOXY)-BENZAMIDE
Authors:Mitchell, D.D, Pickens, J.C, Korotkov, K, Fan, E, Hol, W.G.J.
Deposit date:2003-07-11
Release date:2004-03-09
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:3,5-Substituted phenyl galactosides as leads in designing effective cholera toxin antagonists; synthesis and crystallographic studies
Bioorg.Med.Chem., 12, 2004
1PZK
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BU of 1pzk by Molmil
Cholera Toxin B-Pentamer Complexed With N-Acyl Phenyl Galactoside 9h
Descriptor: Cholera Toxin B Subunit, N-{3-[4-(3-AMINO-PROPYL)-PIPERAZIN-1-YL]-PROPYL}-3-(2-THIOPHEN-2-YL-ACETYLAMINO)-5-(3,4,5-TRIHYDROXY-6-HYDROXYMETHYL-TETRAHYDRO-PYRAN-2-YLOXY)-BENZAMIDE
Authors:Mitchell, D.D, Pickens, J.C, Korotkov, K, Fan, E, Hol, W.G.J.
Deposit date:2003-07-11
Release date:2004-03-09
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:3,5-Substituted phenyl galactosides as leads in designing effective cholera toxin antagonists; synthesis and crystallographic studies
Bioorg.Med.Chem., 12, 2004
1PV2
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BU of 1pv2 by Molmil
Native Form 2 E.coli Chaperone Hsp31
Descriptor: Chaperone protein hchA
Authors:Quigley, P.M, Korotkov, K, Baneyx, F, Hol, W.G.J.
Deposit date:2003-06-26
Release date:2004-01-13
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.71 Å)
Cite:A new native EcHsp31 structure suggests a key role of structural flexibility for chaperone function.
Protein Sci., 13, 2004
3P2P
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BU of 3p2p by Molmil
ENHANCED ACTIVITY AND ALTERED SPECIFICITY OF PHOSPHOLIPASE A2 BY DELETION OF A SURFACE LOOP
Descriptor: CALCIUM ION, PHOSPHOLIPASE A2
Authors:Dijkstra, B.W, Thunnissen, M.M.G.M, Kalk, K.H, Drenth, J.
Deposit date:1989-11-29
Release date:1990-01-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Enhanced activity and altered specificity of phospholipase A2 by deletion of a surface loop.
Science, 244, 1989
2QAC
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BU of 2qac by Molmil
The closed MTIP-MyosinA-tail complex from the malaria parasite invasion machinery
Descriptor: Myosin A tail domain interacting protein MTIP, Myosin-A
Authors:Bosch, J, Turley, S, Roach, C.M, Daly, T.M, Bergman, L.W, Hol, W.G.J, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:2007-06-14
Release date:2007-06-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The Closed MTIP-Myosin A-Tail Complex from the Malaria Parasite Invasion Machinery.
J.Mol.Biol., 372, 2007
2QV8
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BU of 2qv8 by Molmil
Structure of the minor pseudopilin EpsH from the Type 2 Secretion System of Vibrio cholerae
Descriptor: General secretion pathway protein H
Authors:Yanez, M.E, Korotkov, K.V, Abendroth, J, Hol, W.G.J.
Deposit date:2007-08-07
Release date:2008-02-26
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of the minor pseudopilin EpsH from the Type 2 secretion system of Vibrio cholerae.
J.Mol.Biol., 377, 2008
3KSV
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BU of 3ksv by Molmil
Hypothetical protein from Leishmania major
Descriptor: Uncharacterized protein, ZINC ION
Authors:Han, G.W, Merritt, E.A, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:2009-11-23
Release date:2010-01-12
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Hypothetical protein (HIT family) from Leishmania major
To be Published
3KPA
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Ubiquitin fold modifier conjugating enzyme from Leishmania major (probable)
Descriptor: probable Ubiquitin fold modifier conjugating enzyme
Authors:Han, G.W, Le Trong, I, Merritt, E.A, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:2009-11-16
Release date:2009-12-01
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Ubiquitin fold modifier conjugating enzyme from Leishmania major (probable)
To be Published
3NYV
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BU of 3nyv by Molmil
Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with non-specific inhibitor WHI-P180
Descriptor: 4-[3-HYDROXYANILINO]-6,7-DIMETHOXYQUINAZOLINE, Calmodulin-domain protein kinase 1
Authors:Larson, E.T, Merritt, E.A, Medical Structural Genomics of Pathogenic Protozoa (MSGPP)
Deposit date:2010-07-15
Release date:2010-07-28
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Binding modes of non-specific inhibitors of Calcium-Dependent Protein Kinase 1 (CDPK1) from T. gondii and C. parvum
To be Published
2I4S
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BU of 2i4s by Molmil
PDZ domain of EpsC from Vibrio cholerae, residues 204-305
Descriptor: General secretion pathway protein C
Authors:Korotkov, K.V, Krumm, B, Bagdasarian, M, Hol, W.G.J.
Deposit date:2006-08-22
Release date:2006-10-17
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Structural and Functional Studies of EpsC, a Crucial Component of the Type 2 Secretion System from Vibrio cholerae.
J.Mol.Biol., 363, 2006
2I6V
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PDZ domain of EpsC from Vibrio cholerae, residues 219-305
Descriptor: General secretion pathway protein C
Authors:Korotkov, K.V, Krumm, B, Bagdasarian, M, Hol, W.G.J.
Deposit date:2006-08-29
Release date:2006-10-17
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Structural and Functional Studies of EpsC, a Crucial Component of the Type 2 Secretion System from Vibrio cholerae.
J.Mol.Biol., 363, 2006

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