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3NYV

Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with non-specific inhibitor WHI-P180

Summary for 3NYV
Entry DOI10.2210/pdb3nyv/pdb
Related3i79 3i7b 3i7c 3mwu 3n51 3ncg
DescriptorCalmodulin-domain protein kinase 1, 4-[3-HYDROXYANILINO]-6,7-DIMETHOXYQUINAZOLINE (3 entities in total)
Functional Keywordsserine/threonine protein kinase, transferase, calcium-binding, atp-binding, calmodulin, ef hand, bumped kinase inhibitor, structural genomics, medical structural genomics of pathogenic protozoa, msgpp, transferase-transferase inhibitor complex, transferase/transferase inhibitor
Biological sourceToxoplasma gondii
Total number of polymer chains1
Total formula weight56274.54
Authors
Larson, E.T.,Merritt, E.A.,Medical Structural Genomics of Pathogenic Protozoa (MSGPP) (deposition date: 2010-07-15, release date: 2010-07-28, Last modification date: 2023-11-22)
Primary citationLarson, E.T.,Ojo, K.K.,Kim, J.E.,Verlinde, C.L.M.J.,Buckner, F.S.,Hol, W.G.J.,Merritt, E.A.,Van Voorhis, W.C.
Binding modes of non-specific inhibitors of Calcium-Dependent Protein Kinase 1 (CDPK1) from T. gondii and C. parvum
To be Published,
Experimental method
X-RAY DIFFRACTION (1.88 Å)
Structure validation

217705

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