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1DUZ
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BU of 1duz by Molmil
HUMAN CLASS I HISTOCOMPATIBILITY ANTIGEN (HLA-A 0201) IN COMPLEX WITH A NONAMERIC PEPTIDE FROM HTLV-1 TAX PROTEIN
Descriptor: BETA-2 MICROGLOBULIN, HLA-A*0201, HTLV-1 OCTAMERIC TAX PEPTIDE
Authors:Khan, A.R, Baker, B.M, Ghosh, P, Biddison, W.E, Wiley, D.C.
Deposit date:2000-01-19
Release date:2000-02-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The structure and stability of an HLA-A*0201/octameric tax peptide complex with an empty conserved peptide-N-terminal binding site.
J.Immunol., 164, 2000
1DUY
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BU of 1duy by Molmil
CRYSTAL STRUCTURE OF HLA-A*0201/OCTAMERIC TAX PEPTIDE COMPLEX
Descriptor: BETA-2 MICROGLOBULIN, HLA-A2*0201, HTLV-1 OCTAMERIC TAX PEPTIDE
Authors:Khan, A.R, Baker, B.M, Ghosh, P, Biddison, W.E, Wiley, D.C.
Deposit date:2000-01-19
Release date:2000-02-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:The structure and stability of an HLA-A*0201/octameric tax peptide complex with an empty conserved peptide-N-terminal binding site.
J.Immunol., 164, 2000
1TVB
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BU of 1tvb by Molmil
Crystal structure of Melanoma Antigen gp100(209-217) Bound to Human Class I MHC HLA-A2
Descriptor: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
Authors:Borbulevych, O.Y, Baker, B.M.
Deposit date:2004-06-29
Release date:2005-04-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Increased Immunogenicity of an Anchor-Modified Tumor-Associated Antigen Is Due to the Enhanced Stability of the Peptide/MHC Complex: Implications for Vaccine Design
J.Immunol., 174, 2005
1TVH
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BU of 1tvh by Molmil
Crystal structure of Modified Melanoma Antigen gp100(209-T2M) Bound to Human Class I MHC HLA-A2
Descriptor: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
Authors:Borbulevych, O.Y, Baker, B.M.
Deposit date:2004-06-29
Release date:2005-04-19
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.802 Å)
Cite:Increased Immunogenicity of an Anchor-Modified Tumor-Associated Antigen Is Due to the Enhanced Stability of the Peptide/MHC Complex: Implications for Vaccine Design
J.Immunol., 174, 2005
1QRN
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BU of 1qrn by Molmil
CRYSTAL STRUCTURE OF HUMAN A6 TCR COMPLEXED WITH HLA-A2 BOUND TO ALTERED HTLV-1 TAX PEPTIDE P6A
Descriptor: BETA-2 MICROGLOBULIN, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, A-2 ALPHA CHAIN, ...
Authors:Ding, Y.H, Baker, B.M, Garboczi, D.N, Biddison, W.E, Wiley, D.C.
Deposit date:1999-06-14
Release date:1999-10-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Four A6-TCR/peptide/HLA-A2 structures that generate very different T cell signals are nearly identical.
Immunity, 11, 1999
2GIT
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BU of 2git by Molmil
Human Class I MHC HLA-A2 in complex with the modified HTLV-1 TAX (Y5K-4-[3-Indolyl]-butyric acid) peptide
Descriptor: Beta-2-microglobulin, FORMIC ACID, GLYCEROL, ...
Authors:Borbulevych, O.Y, Baker, B.M.
Deposit date:2006-03-29
Release date:2006-10-03
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:T Cell Receptor Recognition via Cooperative Conformational Plasticity.
J.Mol.Biol., 363, 2006
2GT9
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BU of 2gt9 by Molmil
Human Class I MHC HLA-A2 in complex with the decameric Melan-A/MART-1(26-35) peptide
Descriptor: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
Authors:Borbulevych, O.Y, Baker, B.M.
Deposit date:2006-04-27
Release date:2007-06-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structures of MART-1(26/27-35) Peptide/HLA-A2 Complexes Reveal a Remarkable Disconnect between Antigen Structural Homology and T Cell Recognition
J.Mol.Biol., 372, 2007
2GTW
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BU of 2gtw by Molmil
Human Class I MHC HLA-A2 in complex with the nonameric Melan-A/MART-1(27-35) peptide having A27L substitution
Descriptor: Beta-2-microglobulin, FORMIC ACID, GLYCEROL, ...
Authors:Borbulevych, O.Y, Baker, B.M.
Deposit date:2006-04-28
Release date:2007-06-12
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.548 Å)
Cite:Structures of MART-1(26/27-35) Peptide/HLA-A2 Complexes Reveal a Remarkable Disconnect between Antigen Structural Homology and T Cell Recognition
J.Mol.Biol., 372, 2007
2GJ6
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BU of 2gj6 by Molmil
The complex between TCR A6 and human Class I MHC HLA-A2 with the modified HTLV-1 TAX (Y5K-4-[3-Indolyl]-butyric acid) peptide
Descriptor: 3-INDOLEBUTYRIC ACID, A6-Tcr, Beta-2-microglobulin, ...
Authors:Borbulevych, O.Y, Baker, B.M.
Deposit date:2006-03-30
Release date:2006-10-03
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.56 Å)
Cite:T Cell Receptor Recognition via Cooperative Conformational Plasticity.
J.Mol.Biol., 363, 2006
2GUO
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BU of 2guo by Molmil
Human Class I MHC HLA-A2 in complex with the native nonameric Melan-A/MART-1(27-35) peptide
Descriptor: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
Authors:Borbulevych, O.Y, Baker, B.M.
Deposit date:2006-05-01
Release date:2007-06-12
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structures of MART-1(26/27-35) Peptide/HLA-A2 Complexes Reveal a Remarkable Disconnect between Antigen Structural Homology and T Cell Recognition
J.Mol.Biol., 372, 2007
2GTZ
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BU of 2gtz by Molmil
Human Class I MHC HLA-A2 in complex with the nonameric Melan-A/MART-1(27-35) peptide having A28L substitution
Descriptor: Beta-2-microglobulin, GLYCEROL, HLA-A*0201 heavy chain, ...
Authors:Borbulevych, O.Y, Baker, B.M.
Deposit date:2006-04-28
Release date:2007-06-12
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structures of MART-1(26/27-35) Peptide/HLA-A2 Complexes Reveal a Remarkable Disconnect between Antigen Structural Homology and T Cell Recognition
J.Mol.Biol., 372, 2007
6D78
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BU of 6d78 by Molmil
The complex between high-affinity TCR DMF5(alpha-D26Y,beta-L98W) and human Class I MHC HLA-A2 with the bound MART-1(27-35)peptide
Descriptor: Beta-2-microglobulin, DMF5 alpha chain,DMF5 alpha chain, DMF5 beta chain,DMF5 beta chain, ...
Authors:Hellman, L.M, Singh, N.K.
Deposit date:2018-04-24
Release date:2019-04-03
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.347 Å)
Cite:Improving T Cell Receptor On-Target Specificity via Structure-Guided Design.
Mol. Ther., 27, 2019
6DKP
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BU of 6dkp by Molmil
The complex among DMF5(alpha-D26Y, alpha-Y50A,beta-L98W) TCR, human Class I MHC HLA-A2 and MART-1(26-35)(A27L) peptide
Descriptor: Beta-2-microglobulin, DMF5 T-cell Receptor Alpha Chain fusion, DMF5 T-cell Receptor Beta Chain fusion, ...
Authors:Hellman, L.M, Singh, N.K.
Deposit date:2018-05-30
Release date:2019-04-10
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.966 Å)
Cite:Improving T Cell Receptor On-Target Specificity via Structure-Guided Design.
Mol. Ther., 27, 2019
6HH2
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BU of 6hh2 by Molmil
Rab29 small GTPase bound to GDP
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ras-related protein Rab-7L1
Authors:Khan, A.R, McGrath, E, Waschbusch, D.
Deposit date:2018-08-24
Release date:2019-09-11
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.449 Å)
Cite:LRRK2 binds to the Rab32 subfamily in a GTP-dependent mannerviaits armadillo domain.
Small GTPases, 2019
6HDU
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BU of 6hdu by Molmil
Crystal structure of human Rab38 in complex with GTP
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Ras-related protein Rab-38
Authors:McGrath, E, Waschbusch, D, Khan, A.R.
Deposit date:2018-08-19
Release date:2019-08-28
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.793 Å)
Cite:LRRK2 binds to the Rab32 subfamily in a GTP-dependent mannerviaits armadillo domain.
Small GTPases, 2019
6FF8
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BU of 6ff8 by Molmil
Crystal structure of uncomplexed Rab32 in the active GTP-bound state at 2.13 Angstrom resolution
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Ras-related protein Rab-32
Authors:Khan, A.R, Kecman, T.
Deposit date:2018-01-04
Release date:2019-01-30
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:LRRK2 binds to the Rab32 subfamily in a GTP-dependent mannerviaits armadillo domain.
Small GTPases, 2019
4JFD
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BU of 4jfd by Molmil
Preservation of peptide specificity during TCR-MHC contact dominated affinity enhancement of a melanoma-specific TCR
Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ...
Authors:Rizkallah, P.J, Cole, D.K, Madura, F, Sewell, A.K.
Deposit date:2013-02-28
Release date:2013-05-29
Last modified:2013-07-17
Method:X-RAY DIFFRACTION (2.46 Å)
Cite:T-cell receptor specificity maintained by altered thermodynamics.
J.Biol.Chem., 288, 2013
4JFF
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BU of 4jff by Molmil
Preservation of peptide specificity during TCR-MHC contact dominated affinity enhancement of a melanoma-specific TCR
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
Authors:Rizkallah, P.J, Cole, D.K, Madura, F, Sewell, A.K.
Deposit date:2013-02-28
Release date:2013-05-29
Last modified:2014-04-02
Method:X-RAY DIFFRACTION (2.43 Å)
Cite:T-cell receptor specificity maintained by altered thermodynamics.
J.Biol.Chem., 288, 2013
4JFE
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BU of 4jfe by Molmil
Preservation of peptide specificity during TCR-MHC contact dominated affinity enhancement of a melanoma-specific TCR
Descriptor: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
Authors:Rizkallah, P.J, Cole, D.K, Madura, F, Sewell, A.K.
Deposit date:2013-02-28
Release date:2013-05-29
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:T-cell receptor specificity maintained by altered thermodynamics.
J.Biol.Chem., 288, 2013
4MS8
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BU of 4ms8 by Molmil
42F3 TCR pCPB9/H-2Ld Complex
Descriptor: 42F3 alpha, 42F3 beta, H-2 class I histocompatibility antigen, ...
Authors:Birnbaum, M.E, Adams, J.J, Garcia, K.C.
Deposit date:2013-09-18
Release date:2014-09-24
Last modified:2018-09-26
Method:X-RAY DIFFRACTION (1.922 Å)
Cite:Structural interplay between germline interactions and adaptive recognition determines the bandwidth of TCR-peptide-MHC cross-reactivity.
Nat. Immunol., 17, 2016
4L3E
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BU of 4l3e by Molmil
The complex between high affinity TCR DMF5(alpha-D26Y,beta-L98W) and human Class I MHC HLA-A2 with the bound MART-1(26-35)(A27L) peptide
Descriptor: Beta-2-microglobulin, DMF5 alpha chain, DMF5 beta chain, ...
Authors:Hellman, L.M.
Deposit date:2013-06-05
Release date:2014-06-11
Last modified:2014-08-27
Method:X-RAY DIFFRACTION (2.557 Å)
Cite:Computational design of the affinity and specificity of a therapeutic T cell receptor.
PLOS COMPUT.BIOL., 10, 2014
4MXQ
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BU of 4mxq by Molmil
42F3 TCR pCPC5/H-2Ld Complex
Descriptor: 42F3 alpha VmVh chimera, 42F3 beta VmVh chimera, H-2 class I histocompatibility antigen, ...
Authors:Birnbaum, M.E, Adams, J.J, Garcia, K.C.
Deposit date:2013-09-26
Release date:2015-08-19
Last modified:2018-09-26
Method:X-RAY DIFFRACTION (2.596 Å)
Cite:Structural interplay between germline interactions and adaptive recognition determines the bandwidth of TCR-peptide-MHC cross-reactivity.
Nat. Immunol., 17, 2016
4MVB
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BU of 4mvb by Molmil
42F3 pCPB7/H-2Ld Complex
Descriptor: 42F3 alpha VmCh, 42F3 beta VmCh, H-2 class I histocompatibility antigen, ...
Authors:Birnbaum, M.E, Adams, J.J, Garcia, K.C.
Deposit date:2013-09-23
Release date:2015-08-19
Last modified:2018-09-26
Method:X-RAY DIFFRACTION (3.088 Å)
Cite:Structural interplay between germline interactions and adaptive recognition determines the bandwidth of TCR-peptide-MHC cross-reactivity.
Nat. Immunol., 17, 2016
4N0C
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BU of 4n0c by Molmil
42F3 TCR pCPE3/H-2Ld complex
Descriptor: 42F3 VmCh alpha, 42F3 VmCh beta, H-2 class I histocompatibility antigen, ...
Authors:Birnbaum, M.E, Adams, J.J, Garcia, K.C.
Deposit date:2013-10-01
Release date:2015-08-19
Last modified:2018-09-26
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural interplay between germline interactions and adaptive recognition determines the bandwidth of TCR-peptide-MHC cross-reactivity.
Nat. Immunol., 17, 2016
4N5E
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BU of 4n5e by Molmil
42F3 TCR pCPA12/H-2Ld complex
Descriptor: 42F3 alpha VmCh, 42F3 beta VmCh, H-2 class I histocompatibility antigen, ...
Authors:Birnbaum, M.E, Adams, J.J, Garcia, K.C.
Deposit date:2013-10-09
Release date:2015-08-19
Last modified:2018-09-26
Method:X-RAY DIFFRACTION (3.059 Å)
Cite:Structural interplay between germline interactions and adaptive recognition determines the bandwidth of TCR-peptide-MHC cross-reactivity.
Nat. Immunol., 17, 2016

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