6VRQ
| Crystal structure of gl12A21 Fab in complex with anti-idiotypic iv12 Fab | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Aljedani, S.S, Weidle, C, Pancera, M. | Deposit date: | 2020-02-08 | Release date: | 2021-02-17 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.57 Å) | Cite: | Development of a VRC01-class germline targeting immunogen derived from anti-idiotypic antibodies. Cell Rep, 35, 2021
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6VJN
| Structure of NHP D11A.B5Fab in complex with 16055 V2b peptide | Descriptor: | D11A.B5 Fab Heavy chain, D11A.B5 Fab Light chain, SODIUM ION, ... | Authors: | Singh, S, Liban, T.J, Pancera, M. | Deposit date: | 2020-01-16 | Release date: | 2021-01-20 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structurally related but genetically unrelated antibody lineages converge on an immunodominant HIV-1 Env neutralizing determinant following trimer immunization. Plos Pathog., 17, 2021
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6WAS
| Structure of D19.PA8 Fab in complex with 1FD6 16055 V1V2 scaffold | Descriptor: | 1FD6 16055 V1V2 scaffold, 2-acetamido-2-deoxy-beta-D-glucopyranose, GN1_PA8 Fab Heavy chain, ... | Authors: | Singh, S, Liban, T.J, Pancera, M. | Deposit date: | 2020-03-26 | Release date: | 2021-03-31 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.904 Å) | Cite: | Structurally related but genetically unrelated antibody lineages converge on an immunodominant HIV-1 Env neutralizing determinant following trimer immunization. Plos Pathog., 17, 2021
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7MU4
| Crystal Structure of HPV L1-directed D24.M01Fab | Descriptor: | D24.M01 Fab Heavy Chain, D24.M01 Fab Light Chain, DI(HYDROXYETHYL)ETHER | Authors: | Singh, S, Pancera, M. | Deposit date: | 2021-05-14 | Release date: | 2022-05-18 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | Structural Characterisation of Immune Responses to HPV Vaccination To Be Published
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7M3I
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7MX8
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7MYT
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5UTY
| Crystal Structure of a Stabilized DS-SOSIP.mut4 BG505 gp140 HIV-1 Env Trimer, Containing Mutations I201C-P433C (DS), L154M, N300M, N302M, T320L in Complex with Human Antibodies PGT122 and 35O22 at 4.1 Angstrom | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 35O22 Fab heavy chain, ... | Authors: | Xu, K, Chuang, G.-Y, Pancera, M, Kwong, P.D. | Deposit date: | 2017-02-15 | Release date: | 2017-03-29 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (3.412 Å) | Cite: | Structure-Based Design of a Soluble Prefusion-Closed HIV-1 Env Trimer with Reduced CD4 Affinity and Improved Immunogenicity. J. Virol., 91, 2017
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7RQQ
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7RQR
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7RQP
| Structure of PfCSP NPNV binding antibody L9 | Descriptor: | L9 Heavy Chain, L9 Kappa Chain | Authors: | Hurlburt, N.K, Pancera, M. | Deposit date: | 2021-08-06 | Release date: | 2022-03-02 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.98 Å) | Cite: | The light chain of the L9 antibody is critical for binding circumsporozoite protein minor repeats and preventing malaria. Cell Rep, 38, 2022
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6OL5
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6OL7
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8EMZ
| Structure of GII.17 norovirus in complex with Nanobody 2 | Descriptor: | 1,2-ETHANEDIOL, GII.17 P domain, Nanobody 2 | Authors: | Kher, G, Sabin, C, Pancera, M, Koromyslova, A, Hansman, G. | Deposit date: | 2022-09-28 | Release date: | 2023-03-15 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Direct Blockade of the Norovirus Histo-Blood Group Antigen Binding Pocket by Nanobodies. J.Virol., 97, 2023
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8EN5
| Structure of GII.4 norovirus in complex with Nanobody 56 | Descriptor: | 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GII.4 P domain, ... | Authors: | Kher, G, Sabin, C, Pancera, M, Koromyslova, A, Hansman, G. | Deposit date: | 2022-09-28 | Release date: | 2023-03-15 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Direct Blockade of the Norovirus Histo-Blood Group Antigen Binding Pocket by Nanobodies. J.Virol., 97, 2023
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8EN6
| Structure of GII.4 norovirus in complex with Nanobody 76 | Descriptor: | 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, GII.4 P domain, ... | Authors: | Kher, G, Sabin, C, Pancera, M, Koromyslova, A, Hansman, G. | Deposit date: | 2022-09-28 | Release date: | 2023-03-15 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Direct Blockade of the Norovirus Histo-Blood Group Antigen Binding Pocket by Nanobodies. J.Virol., 97, 2023
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8EN3
| Structure of GII.17 norovirus in complex with Nanobody 45 | Descriptor: | 1,2-ETHANEDIOL, Capsid protein VP1, Nanobody 45 | Authors: | Kher, G, Sabin, C, Pancera, M, Koromyslova, A, Hansman, G. | Deposit date: | 2022-09-28 | Release date: | 2023-03-15 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Direct Blockade of the Norovirus Histo-Blood Group Antigen Binding Pocket by Nanobodies. J.Virol., 97, 2023
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8EN4
| Structure of GII.4 norovirus in complex with Nanobody 53 | Descriptor: | 1,2-ETHANEDIOL, Nanobody 53, VP1 | Authors: | Kher, G, Sabin, C, Koromyslova, A, Pancera, M, Hansman, G. | Deposit date: | 2022-09-28 | Release date: | 2023-03-15 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Direct Blockade of the Norovirus Histo-Blood Group Antigen Binding Pocket by Nanobodies. J.Virol., 97, 2023
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8EN0
| Structure of GII.17 norovirus in complex with Nanobody 7 | Descriptor: | Capsid protein VP1, Nanobody 7 | Authors: | Kher, G, Sabin, C, Koromyslova, A, Pancera, M, Hansman, G. | Deposit date: | 2022-09-28 | Release date: | 2023-03-15 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.99 Å) | Cite: | Direct Blockade of the Norovirus Histo-Blood Group Antigen Binding Pocket by Nanobodies. J.Virol., 97, 2023
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8EMY
| Structure of GII.4 norovirus in complex with Nanobody 82 | Descriptor: | 1,2-ETHANEDIOL, GII.4 P domain, Nanobody 82 | Authors: | Kher, G, Sabin, C, Pancera, M, Koromyslova, A, Hansman, G. | Deposit date: | 2022-09-28 | Release date: | 2023-03-15 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Direct Blockade of the Norovirus Histo-Blood Group Antigen Binding Pocket by Nanobodies. J.Virol., 97, 2023
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8EN2
| Structure of GII.10 norovirus in complex with Nanobody 34 | Descriptor: | 1,2-ETHANEDIOL, GII.10 P domain, Nanobody 34 | Authors: | Kher, G, Sabin, C, Koromyslova, A, Pancera, M, Hansman, G. | Deposit date: | 2022-09-28 | Release date: | 2023-03-15 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Direct Blockade of the Norovirus Histo-Blood Group Antigen Binding Pocket by Nanobodies. J.Virol., 97, 2023
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8EN1
| Structure of GII.4 norovirus in complex with Nanobody 30 | Descriptor: | GII.4 P domain, Nanobody 30 | Authors: | Kher, G, Sabin, C, Pancera, M, Koromyslova, A, Hansman, G. | Deposit date: | 2022-09-28 | Release date: | 2023-03-15 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Direct Blockade of the Norovirus Histo-Blood Group Antigen Binding Pocket by Nanobodies. J.Virol., 97, 2023
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6C5V
| An anti-gH/gL antibody that neutralizes dual-tropic infection defines a site of vulnerability on Epstein-Barr virus | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody Fab AMMO1 heavy chain, Antibody Fab AMMO1 light chain, ... | Authors: | Snijder, J, Ortego, M.S, Weidle, C, Stuart, A.B, Gray, M.A, McElrath, M.J, Pancera, M, Veesler, D, McGuire, A.T, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | Deposit date: | 2018-01-16 | Release date: | 2018-05-02 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (4.8 Å) | Cite: | An Antibody Targeting the Fusion Machinery Neutralizes Dual-Tropic Infection and Defines a Site of Vulnerability on Epstein-Barr Virus. Immunity, 48, 2018
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7RDW
| Crystal Structure of FH1 Fab bound to HXb2 HIV-1 gp120 core | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, AMMONIUM ION, ... | Authors: | Weidle, C, Pancera, M. | Deposit date: | 2021-07-12 | Release date: | 2022-05-25 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.55 Å) | Cite: | Characterization of a vaccine-elicited human antibody with sequence homology to VRC01-class antibodies that binds the C1C2 gp120 domain. Sci Adv, 8, 2022
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7RAQ
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