7RQQ

Structure of chimeric antibody F10heavy_L9light with PfCSP peptide NANPNVDP

Summary for 7RQQ

• Entry DOI: 10.2210/pdb7rqq/pdb
• Related: 7RQP
• Descriptor: F10 Heavy Chain, L9 Kappa Chain, PfCSP peptide NANPNVDP, ... (6 entities in total)
• Functional Keywords: malaria, antibody, immune system
• Biological source: Homo sapiens; More
• Total number of polymer chains: 3
• Total formula weight: 49193.68

Authors

Hurlburt, N.K.,Pancera, M. (deposition date: 2021-08-06, release date: 2022-03-02, Last modification date: 2023-10-18)

• Primary citation: Wang, L.T.,Hurlburt, N.K.,Schon, A.,Flynn, B.J.,Flores-Garcia, Y.,Pereira, L.S.,Kiyuka, P.K.,Dillon, M.,Bonilla, B.,Zavala, F.,Idris, A.H.,Francica, J.R.,Pancera, M.,Seder, R.A.; The light chain of the L9 antibody is critical for binding circumsporozoite protein minor repeats and preventing malaria.; Cell Rep, 38:110367-110367, 2022; PubMed: 35172158; DOI: 10.1016/j.celrep.2022.110367

Experimental method

X-RAY DIFFRACTION (1.89 Å)