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2NBO
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BU of 2nbo by Molmil
Solution structure of the F87M/L110M variant of transthyretin in the monomeric state
Descriptor: Transthyretin
Authors:Kim, J, Oroz, J, Zweckstetter, M.
Deposit date:2016-03-09
Release date:2017-02-22
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Mechanistic basis for the recognition of a misfolded protein by the molecular chaperone Hsp90.
Nat. Struct. Mol. Biol., 24, 2017
6AIL
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BU of 6ail by Molmil
CRYSTAL STRUCTURE AT 1.3 ANGSTROMS RESOLUTION OF A NOVEL UDG, UdgX, FROM Mycobacterium smegmatis
Descriptor: IRON/SULFUR CLUSTER, Uracil DNA glycosylase X
Authors:Ahn, W.C, Aroli, S, Varshney, V, Woo, E.J.
Deposit date:2018-08-24
Release date:2019-05-29
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.335 Å)
Cite:Covalent binding of uracil DNA glycosylase UdgX to abasic DNA upon uracil excision.
Nat.Chem.Biol., 15, 2019
6AJO
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BU of 6ajo by Molmil
Complex form of Uracil DNA glycosylase X and uracil-DNA.
Descriptor: DNA (5'-D(P*(ORP)P*TP*T)-3'), IRON/SULFUR CLUSTER, PHOSPHATE ION, ...
Authors:Ahn, W.C, Aroli, S, Varshney, U, Woo, E.J.
Deposit date:2018-08-28
Release date:2019-05-29
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.269 Å)
Cite:Covalent binding of uracil DNA glycosylase UdgX to abasic DNA upon uracil excision.
Nat.Chem.Biol., 15, 2019
6AJR
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BU of 6ajr by Molmil
Complex form of Uracil DNA glycosylase X and uracil
Descriptor: IRON/SULFUR CLUSTER, URACIL, Uracil DNA glycosylase superfamily protein
Authors:Ahn, W.C, Aroli, S, Varshney, U, Woo, E.J.
Deposit date:2018-08-28
Release date:2019-05-29
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.341 Å)
Cite:Covalent binding of uracil DNA glycosylase UdgX to abasic DNA upon uracil excision.
Nat.Chem.Biol., 15, 2019
3KC6
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BU of 3kc6 by Molmil
Crystal structure of the large c-terminal domain of polymerase basic protein 2 from influenza virus a/viet nam/1203/2004 (h5n1)
Descriptor: 1,2-ETHANEDIOL, Polymerase PB2
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2009-10-20
Release date:2010-03-09
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Biological and structural characterization of a host-adapting amino acid in influenza virus.
Plos Pathog., 6, 2010
3KHW
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BU of 3khw by Molmil
Crystal structure of the large c-terminal domain of polymerase basic protein 2 from influenza virus a/mexico/indre4487/2009(h1n1)
Descriptor: GLYCEROL, Polymerase PB2
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2009-10-31
Release date:2010-03-09
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Biological and structural characterization of a host-adapting amino acid in influenza virus.
Plos Pathog., 6, 2010
4HQQ
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BU of 4hqq by Molmil
Crystal structure of RV144-elicited antibody CH58
Descriptor: CH58 Fab heavy chain, CH58 Fab light chain
Authors:McLellan, J.S, Haynes, B.F, Kwong, P.D.
Deposit date:2012-10-25
Release date:2013-02-06
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Vaccine Induction of Antibodies against a Structurally Heterogeneous Site of Immune Pressure within HIV-1 Envelope Protein Variable Regions 1 and 2.
Immunity, 38, 2013
4HPY
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BU of 4hpy by Molmil
Crystal structure of RV144-elicited antibody CH59 in complex with V2 peptide
Descriptor: CH59 Fab heavy chain, CH59 Fab light chain, Envelope glycoprotein gp160, ...
Authors:McLellan, J.S, Gorman, J, Haynes, B.F, Kwong, P.D.
Deposit date:2012-10-24
Release date:2013-02-06
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Vaccine Induction of Antibodies against a Structurally Heterogeneous Site of Immune Pressure within HIV-1 Envelope Protein Variable Regions 1 and 2.
Immunity, 38, 2013
4HPO
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BU of 4hpo by Molmil
Crystal structure of RV144-elicited antibody CH58 in complex with V2 peptide
Descriptor: CH58 Fab heavy chain, CH58 Fab light chain, Envelope glycoprotein gp160, ...
Authors:McLellan, J.S, Gorman, J, Haynes, B.F, Kwong, P.D.
Deposit date:2012-10-24
Release date:2013-02-06
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.694 Å)
Cite:Vaccine Induction of Antibodies against a Structurally Heterogeneous Site of Immune Pressure within HIV-1 Envelope Protein Variable Regions 1 and 2.
Immunity, 38, 2013
2KI2
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BU of 2ki2 by Molmil
Solution Structure of ss-DNA Binding Protein 12RNP2 Precursor, HP0827(O25501_HELPY) form Helicobacter pylori
Descriptor: Ss-DNA binding protein 12RNP2
Authors:Ma, C, Lee, J, Kim, J, Park, S, Kwon, A, Lee, B.
Deposit date:2009-04-20
Release date:2009-10-20
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:NMR solution structure of HP0827 (O25501_HELPY) from Helicobacter pylori: model of the possible RNA-binding site
J.Biochem., 146, 2009
4QF1
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BU of 4qf1 by Molmil
Crystal structure of unliganded CH59UA, the inferred unmutated ancestor of the RV144 anti-HIV antibody lineage producing CH59
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CH59UA Fab fragment of heavy chain, CHLORIDE ION, ...
Authors:Wiehe, K, Easterhoff, D, Luo, K, Nicely, N.I, Bradley, T, Jaeger, F.H, Dennison, S.M, Zhang, R, Lloyd, K.E, Stolarchuk, C, Parks, R, Sutherland, L.L, Scearce, R.M, Morris, L, Kaewkungwal, J, Nitayaphan, S, Pitisuttithum, P, Rerks-Ngarm, S, Michael, N, Kim, J, Kelsoe, G, Montefiori, D.C, Tomaras, G, Bonsignori, M, Santra, S, Kepler, T.B, Alam, S.M, Moody, M.A, Liao, H.-X, Haynes, B.F.
Deposit date:2014-05-19
Release date:2015-02-18
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Antibody Light-Chain-Restricted Recognition of the Site of Immune Pressure in the RV144 HIV-1 Vaccine Trial Is Phylogenetically Conserved.
Immunity, 41, 2014
4NCS
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BU of 4ncs by Molmil
Human sialidase 2 in complex with 2,3-difluorosialic acid (covalent intermediate)
Descriptor: (2S,3S,4R,5R,6R)-5-acetamido-2,3-bis(fluoranyl)-4-oxidanyl-6-[(1S,2S)-1,2,3-tris(oxidanyl)propyl]oxane-2-carboxylic acid, PHOSPHATE ION, Sialidase-2
Authors:Buchini, S, Gallat, F.-X, Greig, I.R, Kim, J.-H, Wakatsuki, S, Chavas, L.M.G, Withers, S.G.
Deposit date:2013-10-25
Release date:2013-12-25
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.201 Å)
Cite:Tuning mechanism-based inactivators of neuraminidases: mechanistic and structural insights.
Angew.Chem.Int.Ed.Engl., 53, 2014
7DP1
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BU of 7dp1 by Molmil
Crystal structure of FMN and NADPH-dependent nitroreductase NfnB mutant Y88A derived from sphigopyxis sp. strain HMH
Descriptor: FLAVIN MONONUCLEOTIDE, Nitroreductase family protein
Authors:Kim, S.H, Park, S, Rhee, S.
Deposit date:2020-12-17
Release date:2021-09-08
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.003496 Å)
Cite:Structure and substrate specificity determinants of NfnB, a dinitroaniline herbicide-catabolizing nitroreductase from Sphingopyxis sp. strain HMH.
J.Biol.Chem., 297, 2021
7DP0
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BU of 7dp0 by Molmil
Crystal structure of FMN and NADPH-dependent nitroreductase NfnB from sphigopyxis sp. strain HMH
Descriptor: FLAVIN MONONUCLEOTIDE, Nitroreductase family protein
Authors:Kim, S.H, Park, S, Rhee, S.
Deposit date:2020-12-17
Release date:2021-09-08
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.10004139 Å)
Cite:Structure and substrate specificity determinants of NfnB, a dinitroaniline herbicide-catabolizing nitroreductase from Sphingopyxis sp. strain HMH.
J.Biol.Chem., 297, 2021
7DP2
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BU of 7dp2 by Molmil
Crystal structure of FMN and NADPH-dependent nitroreductase NfnB mutant Y88F derived from sphigopyxis sp. strain HMH
Descriptor: FLAVIN MONONUCLEOTIDE, Nitroreductase family protein
Authors:Kim, S.H, Park, S, Rhee, S.
Deposit date:2020-12-17
Release date:2021-09-08
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.40008736 Å)
Cite:Structure and substrate specificity determinants of NfnB, a dinitroaniline herbicide-catabolizing nitroreductase from Sphingopyxis sp. strain HMH.
J.Biol.Chem., 297, 2021
2B9L
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BU of 2b9l by Molmil
Crystal structure of prophenoloxidase activating factor-II from the beetle Holotrichia diomphalia
Descriptor: CALCIUM ION, SULFATE ION, alpha-L-fucopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)][alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Piao, S, Song, Y.-L, Park, S.Y, Lee, B.L, Oh, B.-H, Ha, N.-C.
Deposit date:2005-10-12
Release date:2006-01-03
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of a clip-domain serine protease and functional roles of the clip domains.
Embo J., 24, 2005
8EPA
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BU of 8epa by Molmil
Structure of interleukin receptor common gamma chain (IL2Rgamma) in complex with two antibodies
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cytokine receptor common subunit gamma, REGN7257 Fab heavy chain, ...
Authors:Franklin, M.C, Romero Hernandez, A.
Deposit date:2022-10-05
Release date:2023-01-25
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Blocking common gamma chain cytokine signaling ameliorates T cell-mediated pathogenesis in disease models.
Sci Transl Med, 15, 2023
8EX8
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BU of 8ex8 by Molmil
Human S1P transporter Spns2 in an outward-facing partially occluded conformation (state 2)
Descriptor: Sphingosine-1-phosphate transporter SPNS2
Authors:Ahmed, S, Zhao, H, Dai, Y, Lee, C.H.
Deposit date:2022-10-24
Release date:2023-05-31
Last modified:2023-06-28
Method:ELECTRON MICROSCOPY (4.17 Å)
Cite:Structural and functional insights into Spns2-mediated transport of sphingosine-1-phosphate.
Cell, 186, 2023
8EX7
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BU of 8ex7 by Molmil
Human S1P transporter Spns2 in an outward-facing partially occluded conformation (state 3)
Descriptor: Sphingosine-1-phosphate transporter SPNS2
Authors:Ahmed, S, Zhao, H, Dai, Y, Lee, C.H.
Deposit date:2022-10-24
Release date:2023-05-31
Last modified:2023-06-28
Method:ELECTRON MICROSCOPY (3.53 Å)
Cite:Structural and functional insights into Spns2-mediated transport of sphingosine-1-phosphate.
Cell, 186, 2023
8EX6
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BU of 8ex6 by Molmil
Human S1P transporter Spns2 in an inward-facing open conformation (state 1*)
Descriptor: (2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate, Sphingosine-1-phosphate transporter SPNS2
Authors:Ahmed, S, Zhao, H, Dai, Y, Lee, C.H.
Deposit date:2022-10-24
Release date:2023-05-31
Last modified:2023-06-28
Method:ELECTRON MICROSCOPY (3.54 Å)
Cite:Structural and functional insights into Spns2-mediated transport of sphingosine-1-phosphate.
Cell, 186, 2023
8EX4
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BU of 8ex4 by Molmil
Human S1P transporter Spns2 in an inward-facing open conformation (state 1)
Descriptor: (2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate, Sphingosine-1-phosphate transporter SPNS2
Authors:Ahmed, S, Zhao, H, Dai, Y, Lee, C.H.
Deposit date:2022-10-24
Release date:2023-05-31
Last modified:2023-06-28
Method:ELECTRON MICROSCOPY (2.93 Å)
Cite:Structural and functional insights into Spns2-mediated transport of sphingosine-1-phosphate.
Cell, 186, 2023
8EX5
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BU of 8ex5 by Molmil
Human S1P transporter Spns2 in an outward-facing open conformation (state 4)
Descriptor: Sphingosine-1-phosphate transporter SPNS2
Authors:Ahmed, S, Zhao, H, Dai, Y, Lee, C.H.
Deposit date:2022-10-24
Release date:2023-05-31
Last modified:2023-06-28
Method:ELECTRON MICROSCOPY (3.47 Å)
Cite:Structural and functional insights into Spns2-mediated transport of sphingosine-1-phosphate.
Cell, 186, 2023
5F5R
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BU of 5f5r by Molmil
TRAP1N-ADPNP
Descriptor: Heat shock protein 75 kDa, mitochondrial, MAGNESIUM ION, ...
Authors:Tsai, F.T.F, Lee, S, Sung, N, Lee, J, Chang, C, Joachimiak, A.
Deposit date:2015-12-04
Release date:2016-03-02
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Mitochondrial Hsp90 is a ligand-activated molecular chaperone coupling ATP binding to dimer closure through a coiled-coil intermediate.
Proc.Natl.Acad.Sci.USA, 113, 2016
1O9A
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BU of 1o9a by Molmil
Solution structure of the complex of 1F12F1 from fibronectin with B3 from FnBB from S. dysgalactiae
Descriptor: FIBRONECTIN, FIBRONECTIN BINDING PROTEIN
Authors:Schwarz-Linek, U, Werner, J.M, Pickford, A.R, Pilka, E.S, Gurusiddappa, S, Briggs, J.A.G, Hook, M, Campbell, I.D, Potts, J.R.
Deposit date:2002-12-11
Release date:2003-05-08
Last modified:2018-01-24
Method:SOLUTION NMR
Cite:Pathogenic bacteria attach to human fibronectin through a tandem beta-zipper.
Nature, 423, 2003
2MX0
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BU of 2mx0 by Molmil
Solution structure of HP0268 from Helicobacter pylori
Descriptor: Uncharacterized protein HP_0268
Authors:Lee, K.Y.
Deposit date:2014-12-05
Release date:2015-12-09
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structure-based functional identification of Helicobacter pylori HP0268 as a nuclease with both DNA nicking and RNase activities
Nucleic Acids Res., 43, 2015

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