8WUL
Crystal structure of affinity enhanced TCR in complex with HLA-A*11:01 bound to KRAS-G12V peptide (VVGAVGVGK)
Summary for 8WUL
| Entry DOI | 10.2210/pdb8wul/pdb |
| Descriptor | TCR alpha chain, TCR beta chain, MHC class I antigen, ... (6 entities in total) |
| Functional Keywords | t cell receptor, kras-g12v, hla-a*11:01, immune system |
| Biological source | Mus musculus More |
| Total number of polymer chains | 20 |
| Total formula weight | 374749.94 |
| Authors | Zhang, M.Y.,Luo, L.J.,Xu, W.,Guan, F.H.,Wang, X.Y.,Zhu, P.,Zhang, J.H.,Zhou, X.Y.,Wang, F.,Ye, S. (deposition date: 2023-10-20, release date: 2024-05-01, Last modification date: 2024-05-15) |
| Primary citation | Zhang, M.,Xu, W.,Luo, L.,Guan, F.,Wang, X.,Zhu, P.,Zhang, J.,Zhou, X.,Wang, F.,Ye, S. Identification and affinity enhancement of T-cell receptor targeting a KRAS G12V cancer neoantigen. Commun Biol, 7:512-512, 2024 Cited by PubMed: 38684865DOI: 10.1038/s42003-024-06209-2 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.36 Å) |
Structure validation
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